Abstract: This invention relates to attenuated pestiviruses characterised in that their enzymatic activity residing in glycoprotein ERNS is inactivated, methods of preparing, using and detecting these.

Abstract: A method for managing an external routine in a computer implemented database management system includes creating a first table for storing external routines in a data store coupled to the database management system. An external routine is stored in the first table so that the database management system is allowed to automatically manage any modification related to the external routine and to control access to the external routine such that administrative support is minimized.

Abstract: The invention belongs to the field of animal health and in particular Bovine Viral Diarrhea Virus (BVDV). The invention provides infectious BVDV clones and methods to produce said BVDV clones. The invention further relates to methods of attenuating said clones, attenuated BVDV clones and vaccines comprising said attenuated clones.

Abstract: The invention belongs to the field of animal health and in particular Bovine Viral Diarrhea Virus (BVDV). The invention provides infectious BVDV clones and methods to produce said BVDV clones. The invention further relates to methods of attenuating said clones, attenuated BVDV clones and vaccines comprising said attenuated clones.

Abstract: A system and associated method for data mining prediction is presented according to which the user selects a database table by means of a graphical user interface. Some records in the table are complete, while other records are incomplete. A subset of records of the database table is determined wherein each record of the subset contains a data value in the column selected for prediction. This subset of records is used to generate a model by means of a data mining algorithm, such as linear regression, radial basis function, decision tree or neural network methods. The resulting model is then utilized to predict the empty data fields in the column. After completing the prediction, the predicted values are entered into the column for display to the user.

Abstract: This invention relates to attenuated pestiviruses characterised in that their enzymatic activity residing in glycoprotein ERNS is inactivated, methods of preparing, using and detecting these.

Abstract: Attenuated pestiviruses, in particular attenuated BVDV, wherein at least one mutation is in the coding sequence for glycoprotein Erns and at least another mutation in the coding sequence for Npro which preferably leads to combined inactivation of the RNase activity residing in glycoprotein Erns in addition to the inactivation of the (hypothesized) immunomodulating activity residing in Npro. Methods for attenuating pestiviruses such as BVDV, nucleic acids encoding the pestiviruses, in particular BVDV, compositions and vaccines comprising the attenuated pestiviruses, in particular BVDV, of the invention.

Abstract: Genes to be compared are listed by their gene expression profiles and processed with a similar sequences algorithm that is a time and intensity invariant correlation function to obtain a data set of gene expression pairs and a match fraction for each pair. A threshold match fraction is chosen and a null set is created to hold indices of genes accounted for. Genes are then assigned to clusters by match fraction value if they have a match fraction greater than the threshold. Genes are then removed from clusters if they are represented in more than one cluster by removing a first gene from a cluster when another cluster has another gene with a higher match fraction with the first gene.

Abstract: This invention relates to attenuated pestiviruses characterised in that their enzymatic activity residing in glycoprotein ERNS is inactivated, methods of preparing, using and detecting these.

Abstract: The invention belongs to the field of animal health and in particular Bovine Viral Diarrhea Virus (BVDV). The invention provides infectious BVDV clones and methods to produce said BVDV clones. The invention further relates to methods of attenuating said clones, attenuated BVDV clones and vaccines comprising said attenuated clones.

Abstract: A system and method determine numerical representations for categorical data fields by taking advantage of the redundancy of the data records to allow automatic discovery of an order of the categories. A categorical data field is recoded by creating separate tables for each numerical data field occurring in the data records. The separate tables are sorted according to the numerical values of the respective data fields. The recoding of the categories is performed based on the average sort order of occurrences of the category in a specific sorted table. The standard deviation of the numerical codes provided by the categories is calculated for each of the separate recoding tables. The recoding table with the maximum standard deviation is selected as the recoding table to perform the recoding of the categories contained in the respective categorical data field of the data records.

Abstract: This invention relates to the use of specifically attenuated live BVD (bovine viral diarrhea) viruses for the preparation of a vaccine for use in the prevention and/or treatment of BVDV infections in breeding stocks of cattle, pregnant cows and for fetal protection in pregnant cows.

Abstract: A system and associated method for data mining prediction is presented according to which the user selects a database table by means of a graphical user interface. Some records in the table are complete, while other records are incomplete. A subset of records of the database table is determined wherein each record of the subset contains a data value in the column selected for prediction. This subset of records is used to generate a model by means of a data mining algorithm, such as linear regression, radial basis function, decision tree or neural network methods. The resulting model is then utilized to predict the empty data fields in the column. After completing the prediction, the predicted values are entered into the column for display to the user.

Abstract: This invention relates to attenuated pestiviruses characterised in that their enzymatic activity residing in glycoprotein ERNS is inactivated, methods of preparing, using and detecting these.

Abstract: The present invention is concerned with a hog cholera virus vaccine comprising a polypeptide characteristic of hog cholera virus. Vector vaccines capable to express a nucleic acid sequence encoding such a polypeptide also from part of the present invention. Said polypeptide and nucleic acid sequence can also be used for the detection of hog cholera virus infection.

Abstract: The present invention is concerned with a hog cholera virus vaccine comprising a polypeptide characteristic of hog cholera virus. Vector vaccines capable to express a nucleic acid sequence encoding such a polypeptide also form part of the present invention. Said polypeptide and nucleic acid sequence can also be used for the detection of hog cholera virus infection.

Abstract: The present invention is concerned with a hog cholera virus vaccine comprising a polypeptide characteristic of hog cholera virus. Vector vaccines capable to express a nucleic acid sequence encoding such a polypeptide also form part of the present invention. Said polypeptide and nucleic acid sequence can also be used for the detection of hog cholera virus infection.