Abstract: A method includes obtaining, at an unmanned aerial vehicle, a flight plan for the unmanned aerial vehicle. The flight plan is based on an aircraft type of an aircraft to be inspected. The method also includes coordinating, with a lighting control device onboard the aircraft, activation of a particular exterior light of the aircraft based on the flight plan such that the particular exterior light activates or deactivates when a particular sensor of the one or more sensors is located (i.e., positioned and oriented) to perform a sensing operation on the particular exterior light. The method further includes performing the sensing operation on the particular exterior light using the particular sensor. The method also includes determining a functionality metric associated with the particular exterior light based on the sensing operation.

Abstract: The present disclosure relates to a syringe including a container, for containing a primary fluid, and at least one secondary fluid chamber configured to contain a secondary fluid. The container comprises a proximal end and a distal end and having a distal end opening at the distal end. The syringe further comprises a stopper, movably arranged within the container; and a plunger engageable with the stopper and configured to apply a force to the stopper to move the stopper within the container towards the distal end of the container, to expel primary fluid from the container through the distal end opening. The plunger is further configured to expel secondary fluid from the at least one secondary fluid chamber towards the distal end opening, to expel at least a portion of a residual volume of primary fluid through the distal end opening. A plunger system and assembly for a syringe and methods of expelling fluid from a syringe are also disclosed.

Abstract: A paint package lid (14, 114) includes a base wall (54) having a lid base wall upper surface (56) and a lid base wall lower surface (58), a container coupling rim (60) disposed radially outwardly with respect to the base wall and having a rim upper surface (62), and a closure well (64, 164) disposed radially inwardly with respect to the base wall. The closure well includes a radially outer wall (82) extending downwardly with respect to the base wall, a lower wall (84) extending radially inwardly with respect to the radially outer wall and establishing a lowermost surface (85) of the lid, and a neck (86, 186) disposed radially inwardly with respect to the radially outer wall and extending upwardly from the lower wall and having a closure coupling (95). Also disclosed is a lid and closure assembly and a paint package (10, 110, 210) including the lid.

Abstract: Methods and systems are disclosed related to determining whether there is a proper fit between a user interface and a face of a user. The methods and systems involve generating seal information associated with a seal region between a face of a user and a current user interface donned on the face of the user. The methods and systems are further related to analyzing the seal information to determine whether a leak exists in the seal region. If the leak exists, the systems and methods include analyzing the seal information to determine a location of the leak within the seal region. The systems and methods further include determining a new user interface to replace the current user interface based on the current user interface and the location of the leak.

Abstract: A method for determining a degree of degradation of a user interface worn by an individual during one or more uses of a respiratory therapy system includes receiving data associated with the user interface. The method further includes determining, based at least in part on the received data, a value of at least one degradation indicator associated with the user interface. The method further includes determining the degree of degradation of the user interface based at least in part on the value of the at least one degradation indicator.

Abstract: The present disclosure is directed to embodiments of a tower structure with at least partially additively manufactured, stacked tower sections. Embodiments of the tower structure have a plurality of stacked tower sections, wherein at least one tower section of the plurality of stacked tower sections includes a wall element having one or more printed layers, and a base holding thereon the one or more printed layers. The present disclosure also is directed to a method of manufacturing a tower structure using a stacked tower sections and additive manufacturing. Embodiments of the method include forming a base of poured concrete or cast material, printing and depositing one or more printed layers to form a wall element, and stacking the plurality of tower sections to form the tower structure.

Abstract: A deck system for cargo compartment may including one or more of the following features: a first deck; a second deck, where at least one of the first deck and the second deck divide the cargo compartment into an upper sub-compartment and a lower sub-compartment; and an actuator that is mechanically coupled to the second deck, where operation of the actuator causes at least a portion of the second deck to move vertically relative to the first deck within the cargo compartment.

Abstract: The present invention relates to protein purification, primarily in the chromatographic field. More closely, the invention relates to affinity chromatography using a split intein system with an improved C-intein tag and N-intein ligand, wherein the target protein may be purified as a tag-less end product with a native N-terminus.

Abstract: To automate time series forecasting machine learning pipeline generation, a data allocation size of time series data may be determined based on one or more characteristics of a time series data set. The time series data may be allocated for use by candidate machine learning pipelines based on the data allocation size. Features for the time series data may be determined and cached by the candidate machine learning pipelines. Predictions of each of the candidate machine learning pipelines using at least the one or more features may be evaluated. A ranked list of machine learning pipelines may be automatically generated from the candidate machine learning pipelines for time series forecasting based upon evaluating predictions of each of the one or more candidate machine learning pipelines.

Abstract: The subject matter of this specification can be embodied in, among other things, a method of igniting an air/fuel mixture in an internal combustion engine includes receiving an air/fuel mixture into a pre-combustion chamber, the pre-combustion chamber enclosing a portion of an igniter, igniting the air/fuel mixture in in the pre-combustion chamber with the igniter to produce a flame, directing the flame to eject the pre-combustion chamber through a collection of passages in a wall of the pre-combustion chamber, toward a peripheral wall of a main combustion chamber of the internal combustion engine, igniting, by the flame, air/fuel mixture in the main combustion chamber adjacent the peripheral wall, and then igniting air/fuel mixture in the main combustion chamber in a central region of the main combustion chamber with a propagating flame front of the ignited air/fuel mixture or a portion of the directed flame adjacent the peripheral wall.

Abstract: Some embodiments of the disclosure include inventive compounds (e.g., compounds of Formula (I)) and compositions (e.g., pharmaceutical compositions) which inhibit IRAK and/or FLT3 and which can be used for treating, for example, certain diseases. Some embodiments include methods of using the inventive compound (e.g., in compositions or in pharmaceutical compositions) for administering and treating (e.g., diseases such as hematopoietic cancers, myelodysplastic syndromes (MDS), acute myeloid leukemia (AML), etc.), Additional embodiments provide disease treatment using combinations of the inventive IRAK and/or FLT3 inhibiting compounds with other therapies, such as cancer therapies.

Abstract: Continuous compression molding machines (CCMMs) and methods of continuous compression molding a consolidated thermoplastic matrix composite material are disclosed herein. The CCMMs include a mold, a heat zone heating structure, a consolidation zone heating structure, and a stress relaxation zone heating structure. The CCMMs also include a press structure, a demold structure, and a supply structure. The methods include providing a thermoplastic matrix composite material (TMCM) that includes a thermoplastic material to a CCMM. During the providing, the methods also include heating the TMCM within a heat zone of the CCMM, cooling and consolidating the TMCM within a consolidation zone of the CCMM, relaxing stress within the TMCM within a stress relaxation zone of the CCMM, demolding the TMCM within a demold zone of the CCMM at a mold temperature that is greater than a glass transition temperature of the thermoplastic material, and periodically compressing the TMCM.

Abstract: A mixture including a thiophosphoric acid product suitable for preparing organometallic and/or ashless antiwear additives having improved copper corrosion performance. The thiophosphoric acid product is distilled and recovered as a condensate of the distillation and having a low level of active sulfur.

Abstract: A mask assembly for use as part of an apparatus for supplying a flow of respiratory gases to a user is disclosed. The mask assembly includes a mask body having an inlet through which said flow of respiratory gases are provided to the interior of said mask body. A mask seal assembly comprising a seal of flexible material and a clip of rigid material is attached to the body. The seal has a first side and a second side. The first side of the seal is shaped to approximately match the contours of a user's face and in use substantially seal against a user's face. The second side is attached to the clip. The clip provides an interface extending substantially the full perimeter or periphery of the mask seal assembly for releasably attaching the mask seal assembly to the mask body. The clip comprises a bridging portion spanning outwards from the perimeter or periphery of the mask body to space at least a portion of the second side of the seal outwards from the perimeter or periphery of the mask body.

Abstract: The subject matter of this specification can be embodied in, among other things, a hydrogen fuel cell anode control system including a hydrogen inlet configured to receive pressurized hydrogen, a hydrogen outlet configured to be fluidically coupled to an anode manifold of a hydrogen fuel cell, a recirculation inlet configured to receive overflow hydrogen from the anode manifold, a hydrogen pressure regulator configured to receive pressurized hydrogen from the hydrogen inlet, a hydrogen recirculation module configured to mix hydrogen received from the hydrogen pressure regulator and the recirculation inlet, and provide a hydrogen mixture to the hydrogen outlet, a differential pressure measurement module configured to measure a differential pressure between the anode manifold and a cathode manifold of the hydrogen fuel cell, and a controller configured to control at least one of the hydrogen pressure regulator or the hydrogen recirculation module based on the measured differential pressure.

Abstract: Disclosed is a surgical fixation device to mount on bone. This device does not utilize screws and achieves stability via applying force to the inner wall of the bore and is therefore faster, easier to use, and less user dependent. The device facilitates fast, easy anchoring system for use with other devices that require rigid fixation to bone. The device provides for intermittent mounting of tools, equipment, and/or accessories to a cylindrical bore in bone for use in surgical applications without compromising surrounding bine structure such as done by the use of bone screws. Rigid fixation to bone is a common requirement for surgical procedures for placement of tools, monitoring systems, positional systems, or used as fiducial markers. The present fixation device removably mounts on bone without the disadvantages associated with bone screws and other fixation devices.

Abstract: A system is provided comprising a robotic instrument for use with a tool. In some versions, the robotic instrument comprises a hand-held portion to be held by a user and a tool support movably coupled to the hand-held portion to support the tool. The robotic instrument further includes an actuator assembly operatively attached to the tool support and the hand-held portion and configured to move the tool support relative to the hand-held portion in a plurality of degrees of freedom. The robotic instrument may includes a handle alignment member extending from the hand-held portion. At least a portion of the handle alignment member and a tool plane defined by the tool are aligned when the tool support has an optimal range of motion relative to the hand-held portion.

Abstract: An interface for positive pressure respiratory therapy includes a mask assembly having a mask seal and a mask shell. The mask assembly is positioned lower than and exposes a bridge of the user's nose. The mask seal includes first and second portions on respective first and second sides of a nasal region that contact opposing sides of the user's nose. The first and second portions each include supports that help maintain a shape of the mask seal. A pair of covers can be supported relative to the mask assembly and adjacent a respective one of the first and second portions of the mask seal. The covers limit expansion of the first and second portions of the mask seal in response to pressurized air within the mask seal. The supports of the first and second portions can transfer load from the mask seal to the covers.

Abstract: An oral product includes a body that is wholly receivable in an oral cavity. The body includes a mouth-soluble polymer matrix, cellulosic fibers embedded in the mouth-soluble polymer matrix, and nicotine or a derivative thereof dispersed in the mouth-soluble polymer matrix. The oral product is adapted to release the nicotine or a derivative thereof from the body when the body is received within the oral cavity and exposed to saliva.

Abstract: A composite skin is attached to an underlying structure by fasteners that are countersunk into the structure. The composite skin comprises a thermoplastic material that has been melted and formed into a countersink in the structure using a heated tool.