Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.

Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.

Abstract: Various illustrative embodiments disclosed herein generally pertain to detecting defects by using a radio-frequency debugging signal transmitted by a transmitting antenna array towards a receiving antenna located in a far-field region of the transmitting antenna array. The radio-frequency debugging signal, which is configured to provide information pertaining to a signal radiation distribution of the transmitting antenna array, is received in the receiving antenna and conveyed to a test unit. The test unit digitizes the received radio-frequency debugging signal to obtain a digital dataset and applies a back-propagation algorithm to the digital dataset for deriving a reconstructed near-field representation of the transmitting array.

Abstract: Various illustrative embodiments disclosed herein generally pertain to an RF reflector incorporating a number of reflection apodization elements, each of which is mounted upon a signal reflecting surface of the RF reflector with an inner edge in substantial contact with an inner portion of the signal reflecting surface and an outer edge elevated above a peripheral portion of the signal reflecting surface. The outer edge is elevated to a height corresponding to a quarter-wavelength of a predefined wavelength. This arrangement bestows a gradually variant reflectance characteristic to the RF reflector, with the inner edge of each reflection apodization element providing substantially the same amount of reflectance as the signal reflecting surface of the RF reflector and the outer edge providing substantially no reflectance at the peripheral portion of the signal reflecting surface.

Abstract: The disclosure relates to substituted pyridines, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.

Abstract: Compounds of formula (I), pharmaceutically acceptable salts thereof, and uses of the compounds of formula (I) for treating bacterial infections are disclosed.

Abstract: The present disclosure relates to substituted pyridinones, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.

Abstract: The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.

Abstract: A bow label for a beverage container is disclosed herein. The bow label may include a first sheet at least partially attached to the beverage container. The bow label also may include a second sheet at least partially attached to the first sheet. The first sheet and the second sheet may include a first configuration and a second configuration. In addition, the bow label may include a pull cord disposed between and at least partially attached to the first sheet and the second sheet. In this manner, movement of the pull cord may move the first sheet and the second sheet between the first configuration and the second configuration. In some instances, the second configuration may include a bow-like shape.

Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.

Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.

Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.

Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.

Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.

Abstract: Compounds of formula (I), pharmaceutically acceptable salts thereof, and uses of the compounds of formula (I) for treating bacterial infections are disclosed.

Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.

Abstract: A bow label for a beverage container is disclosed herein. The bow label may include a first sheet at least partially attached to the beverage container. The bow label also may include a second sheet at least partially attached to the first sheet. The first sheet and the second sheet may include a first configuration and a second configuration. In addition, the bow label may include a pull cord disposed between and at least partially attached to the first sheet and the second sheet. In this manner, movement of the pull cord may move the first sheet and the second sheet between the first configuration and the second configuration. In some instances, the second configuration may include a bow-like shape.

Abstract: Compounds of formula (I), pharmaceutically acceptable salts thereof, and uses of the compounds of formula (I) for treating bacterial infections are disclosed.

Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.

Abstract: Analyte separation systems for use in conjunction with chromatography separation devices and techniques are described. Disclosed systems include modular components that can provide for individualized design of separation schemes to better fit the needs of the user. In addition, the systems can be automated for efficient use of time. The system can include a mixing module for combination of fractions with an agent that can improve the recovery of the analyte from the fraction. Other modules can remove materials from the fluid flow through the system as waste or for recapture. Additional modules can be combined so as to provide parallel processing of multiple streams, which can further improve efficiency of the system.