Abstract: The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.

Abstract: The present invention relates to compounds of Formula (I): to pharmaceutically acceptable salts thereof, to methods of using them to treat bacterial infections, and to methods for their preparation.

Abstract: A deployable photonic link including a deployable length of optical fiber and an interface module fusion spliced to at least one end of the optical fiber so that the module is directly connected to the fiber. The interface module including at least one of: an input for receiving a first electrical signal including a first radio frequency (RF) signal component; and an output for outputting a second RF signal component. The interface module further including, respectively, at least one of: a device for receiving the first electrical signal from the input and for producing an optical signal modulated with the first RF signal component for transmission in the optical fiber; and a device for receiving a modulated optical signal and for producing therefrom the second RF signal component for output at the output. An interface module may also contain both the input and the output and the devices for receiving RF signals and for receiving modulated optical signals.

Abstract: Methods and systems for communicating expense management information between an expense management system and a mobile device are provided. The methods and systems include one or more applications for a mobile device, such as mobile phone, that enable a user, such as an expense manager for an entity such as a business entity or other organization, to use their mobile device to communicate and exchange data with an expense management system, such as a telecommunications expense management system. The methods and systems enable an expense manager to review and approve invoices, generate graphics to review usage or other data, and conduct data searches relative to the expenses being managed.

Abstract: The present invention relates to compounds of Formula (I); to pharmaceutically acceptable salts thereof, to methods of using them to treat bacterial infections, and to methods for their preparation.

Abstract: Methods of using computer based models for simulating a porous media.

Abstract: An antenna system including: an input port configured to receive tracking mode signals, in two orthogonal polarisations, from a target; a tracking coupler, configured to receive the tracking mode signals from the input port, the tracking coupler including: a first pair of opposed slot couplers configured to extract tracking signals from the tracking mode signals in a first one of the orthogonal polarisations, and a second pair of opposed slot couplers configured to extract tracking signals from the tracking mode signals in a second one of the orthogonal polarisations; and a tracking combiner network configured to combine the extracted tracking signals from the pairs of opposed slot couplers to generate tracking output signals for use in controlling the antenna system to track the target.

Abstract: An apparatus and method to cool compressors, condensing coils, and similar devices. The compressor or condensing coil is cooled by the delivery of water, which may be ambient temperature or chilled. In one embodiment, the water is delivered to a mesh filter or screen via one or more mist spray nozzles. Water conduits may be integrated with the filter frame. The method to control the delivery of the water is designed to conserve water. The control circuit comprises a microcontroller device which contains programming that receives inputs, including but not limited to, outside ambient air temperature, condenser liquid line temperature, relative humidity and electric current, and uses said inputs to provide a stepwise level of control (“solenoid open time”) of water delivery commensurate with outside air temperature and relative humidity.

Abstract: An apparatus and method to cool compressors, condensing coils, and similar devices. The compressor or condensing coil is cooled by the delivery of water, which may be ambient temperature or chilled. In one embodiment, the water is delivered to a mesh filter or screen via one or more mist spray nozzles. Water conduits may be integrated with the filter frame. The method to control the delivery of the water is designed to conserve water. The control circuit comprises a microcontroller device which contains programming that receives inputs, including but not limited to, outside ambient air temperature, condenser liquid line temperature, relative humidity and electric current, and uses said inputs to provide a stepwise level of control (“solenoid open time”) of water delivery commensurate with outside air temperature and relative humidity.

Abstract: A first party provides a key phrase to a second party so that the second party can later initiate and send an electronic communication, such as an email message, to the first party with the key phrase included, typically in a prominent fashion such as in the subject line of the email message. In this way, the first party recipient of the email message can readily tell that the electronic communication was sent by the second party sender of the email message thus providing a measure of trust in the electronic communication.

Abstract: A deployable photonic link including a deployable length of optical fiber and an interface module fusion spliced to at least one end of the optical fiber so that the module is directly connected to the fiber. The interface module including at least one of: an input for receiving a first electrical signal including a first radio frequency (RF) signal component; and an output for outputting a second RF signal component. The interface module further including, respectively, at least one of: a device for receiving the first electrical signal from the input and for producing an optical signal modulated with the first RF signal component for transmission in the optical fiber; and a device for receiving a modulated optical signal and for producing therefrom the second RF signal component for output at the output. An interface module may also contain both the input and the output and the devices for receiving RF signals and for receiving modulated optical signals.

Abstract: A method for modeling fluid depletion in a reservoir is disclosed. A map is divided into cells. For each of the cells a value is stored that is based at least in part on a physical characteristic of the cell. At least one cell that contains a depletion location is identified along with a depletion amount corresponding to that location. An amount of walkers associated with the depletion location is determined. For each walker, a plurality of steps are calculated with each step to an adjacent cell. Each walker starts in the cell containing the depletion location associated with that walker. The visits of all the walkers are recorded by cell. The fluid depletion of each cell is then assessed based at least in part on the number of walker visits for each cell.

Abstract: The present invention relates to compounds of Formula (I); to pharmaceutically acceptable salts thereof, to methods of using them to treat bacterial infections, and to methods for their preparation.

Abstract: Methods, computer programs, and information handling systems for modeling one or more reservoirs are disclosed. The method uses one or more well logs, each for a well at a location and each including one or more Relative amount of Small Size Range of the Size Spectrum of Clastic Particles (RSSRSS) values versus depth. The method includes for one or more well logs: identifying one or more facies units based on RSSRSS values, determining a thickness of one or more facies units. The method includes determining a facies type of one or more facies units, categorizing one or more facies units, and connecting one or more facies units to create a reservoir model.

Abstract: In one aspect, the present invention relates to compounds of Formula (I): to pharmaceutically acceptable salts thereof, to methods of using them to treat bacterial infections, and to method for their preparation.

Abstract: A method for location-based communicating includes defining a first service area and a second service area for a service provider. The method also includes associating, at a memory apparatus accessible to a networked data processing apparatus, the first service area with multiple addresses within the first service area and the second service area with multiple addresses within the second service area.

Abstract: A method for determining absorbent article effectiveness of a virtual absorbent article. The steps of the method include providing a virtual body model, providing a virtual absorbent article model, providing virtual simulation software, running a virtual simulation of deformation of the virtual absorbent article model in proximity with the virtual body model, running a virtual simulation of the fluid balance of the virtual absorbent article model in proximity with the virtual body model, coupling the virtual simulation of deformation of the virtual absorbent article model and the virtual simulation of the fluid balance of the virtual absorbent article model, and determining absorbent article effectiveness of the virtual absorbent article model in proximity with the virtual body model.

Abstract: A method for location-based communicating includes defining a first service area and a second service area for a service provider. The method also includes associating, at a memory apparatus accessible to a networked data processing apparatus, the first service area with multiple addresses within the first service area and the second service area with multiple addresses within the second service area.

Abstract: A method for location-based communicating includes defining a first service area and a second service area for a service provider. The method also includes associating, at a memory apparatus accessible to a networked data processing apparatus, the first service area with multiple locations within the first service area and the second service area with multiple locations within the second service area.

Abstract: In one aspect, the present invention relates to compounds of Formula (I) and to pharmaceutically acceptable salts thereof, wherein: n is 1 to 4; and R3 in each occurrence is independently selected from —X—R5, —W—R6, —C(O)—N(R3a)—S(O)2—R3b, —C(R3a)?N—R3y, C(R3a)?N—N(R3a)—C(O)—R3b, C(R3a)?N—N(R3a)—C(O)2—R3b, —C(R3a)?N—N(R3y)2, —C(R3a)?N—N(R3a)—C(O)—N(R3y)2, —C(NR3a)2)?N—R3y, —C(N(R3a)2)?N—OR3y, —C(N(R3a)2)?N—C(O)—R3b, —C(N(R3a)2?N—S(0)2—R3b, —C(N(R3a)2)?N—CN, —N?C(R3y)2, —N(R3a)—S(O)2—N(R3y)2, —N(R3a)—N(R3y2, —N(R3a)—C(O)—N(R3y)2, —N(R3a)—C(O)—N(R3a)—S(O)2—R3b, —N(R3a)—C(R3a)?N(R3y), —N(R3a)—C(R3a)?N—OR3y, —N(R3a)—C(R3a)?N—C(O)—R3b, —N(R3a)—C(R3a)?N—S(O)2R—3b, —N(R3a)—C(R3a)?N—CN, —N(R3a)—C(N(R3a)2)?N—R3y, —N(R3a)—C(N(R3a)2)?N—OR3y, —N(R3a)—C(N(R3a)2)?N—C(O)—R3b, —N(R3a)—C(N(R3a)2)—N—S(O)2—R3b, —N(R3a)—C(N(R3a)2)—N—CN, —O—C(O)—R3, and —Si(R3b)3; to methods of using them to treat bacterial infections, and to methods for their preparation.