Patents by Inventor Gregory Conn

Gregory Conn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210182332
    Abstract: A device, system and method for anonymously comparing query images to reference images is provided. A computing device receives, from at least one camera, a query image. The computing device generates a query characteristic vector associated with the query image. The computing device applies a mathematical operator on the query characteristic vector to obtain a query vector. The computing device compares the query vector to a reference vector, the reference vector obtained by applying a complementary mathematical operator on a reference characteristic vector associated with a reference image, the complementary mathematical operator comprising a complement of the mathematical operator. The computing device, in response to the comparing indicating a match between the query vector and the reference vector, provides a notification of the match.
    Type: Application
    Filed: December 12, 2019
    Publication date: June 17, 2021
    Inventors: Roger DONALDSON, Gregory CONN
  • Publication number: 20200330491
    Abstract: A composition and method for activating immune cells ex-vivo, or inducing an immune response in a subject including a composition comprising at least one chiral cationic lipid. The chiral cationic lipid in one embodiment comprises a nonsteroidal cationic lipid having a structure represented by formula (I); wherein in R1 is a quaternary ammonium group, Y1 is a space chosen from a hydrocarbon chain, an ester, a ketone, and a peptide, C* is a chiral carbon, R2 and R3 are independently chosen from a saturated fatty acid, an unsaturated fatty acid, an ester-linked hydrocarbon, phosphor-diesters, and combination thereof.
    Type: Application
    Filed: June 12, 2020
    Publication date: October 22, 2020
    Inventors: Elizabeth Ann Vasievich, Weihsu Claire Chen, Kenya N. Toney Johnson, Gregory Conn, Frank Bedu-Addo, Leaf Huang
  • Patent number: 10702541
    Abstract: A composition and method for activating immune cells ex-vivo, or inducing an immune response in a subject including a composition comprising at least one chiral cationic lipid. The chiral cationic lipid in one embodiment comprises a nonsteroidal cationic lipid having a structure represented by formula (I); wherein in R1 is a quaternary ammonium group, Y1 is a spacer chosen from a hydrocarbon chain, an ester, a ketone, and a peptide, C* is a chiral carbon, R2 and R3 are independently chosen from a saturated fatty acid, an unsaturated fatty acid, an ester-linked hydrocarbon, phosphor-diesters, and combinations thereof.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: July 7, 2020
    Assignee: PDS Biotechnology Corporation
    Inventors: Elizabeth Ann Vasievich, Weihsu Claire Chen, Kenya N. Toney Johnson, Gregory Conn, Frank Bedu-Addo, Leaf Huang
  • Publication number: 20190275145
    Abstract: The present disclosure provides vaccine formulations comprising at least one peptide antigen assembly and at least one adjuvant. The disclosure also provides methods of inducing an immune response in a mammal and methods of treating a disease in a mammal utilizing the vaccine formulations.
    Type: Application
    Filed: March 21, 2019
    Publication date: September 12, 2019
    Inventors: Frank Bedu-Addo, Gregory Conn, Eric Jacobson, Carol Mercer, Kenya Johnson
  • Publication number: 20180015114
    Abstract: A composition and method for activating immune cells ex-vivo, or inducing an immune response in a subject including a composition comprising at least one chiral cationic lipid. The chiral cationic lipid in one embodiment comprises a nonsteroidal cationic lipid having a structure represented by formula (I); wherein in R1 is a quaternary ammonium group, Y1 is a spacer chosen from a hydrocarbon chain, an ester, a ketone, and a peptide, C* is a chiral carbon, R2 and R3 are independently chosen from a saturated fatty acid, an unsaturated fatty acid, an ester-linked hydrocarbon, phosphor-diesters, and combinations thereof.
    Type: Application
    Filed: September 12, 2017
    Publication date: January 18, 2018
    Inventors: Elizabeth Ann Vasievich, Weihsu Claire Chen, Kenya N. Toney Johnson, Gregory Conn, Frank Bedu-Addo, Leaf Huang
  • Patent number: 9789129
    Abstract: Compositions and methods for treating immune cells and activating immune responses are disclosed. The compositions comprise one or more optically active chiral cationic lipids.
    Type: Grant
    Filed: April 14, 2009
    Date of Patent: October 17, 2017
    Assignee: PDS Biotechnology Corporation
    Inventors: Elizabeth Ann Vasievich, Weihsu Claire Chen, Kenya Toney Johnson, Gregory Conn, Frank Bedu-Addo, Leaf Huang
  • Publication number: 20150110823
    Abstract: The present disclosure provides vaccine formulations comprising at least one peptide antigen assembly and at least one adjuvant. The disclosure also provides methods of inducing an immune response in a mammal and methods of treating a disease in a mammal utilizing the vaccine formulations.
    Type: Application
    Filed: September 12, 2012
    Publication date: April 23, 2015
    Applicant: PDS BIOTECHNOLOGY CORPORATION
    Inventors: Frank Bedu-Addo, Gregory Conn, Eric Jacobson, Carol Mercer, Kenya Johnson
  • Publication number: 20150093410
    Abstract: The present invention provides compositions and methods for stimulating an immune response using cationic lipids alone or in combination with antigens.
    Type: Application
    Filed: November 3, 2014
    Publication date: April 2, 2015
    Inventors: Weihsu CHEN, Weili YAN, Kenya JOHNSON, Gregory CONN, Frank BEDU-ADDO, Leaf HUANG
  • Patent number: 8877206
    Abstract: The present invention provides compositions and methods for stimulating an immune response using cationic lipids alone or in combination with antigens.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: November 4, 2014
    Assignee: PDS Biotechnology Corporation
    Inventors: Weihsu Chen, Weili Yan, Kenya Toney, Gregory Conn, Frank Bedu-Addo, Leaf Huang
  • Publication number: 20110110972
    Abstract: Compositions and methods for treating immune cells and activating immune responses are disclosed. The compositions comprise one or more optically active chiral cationic lipids.
    Type: Application
    Filed: April 14, 2009
    Publication date: May 12, 2011
    Applicant: PDS BIOTECHNOLOGY CORPORATION
    Inventors: Elizabeth Ann Vasievich, Weihsu Claire Chen, Kenya Toney Johnson, Gregory Conn, Frank Bedu-addo, Leaf Huang
  • Publication number: 20090017057
    Abstract: The present invention provides compositions and methods for stimulating an immune response using cationic lipids alone or in combination with antigens.
    Type: Application
    Filed: March 17, 2008
    Publication date: January 15, 2009
    Applicant: PDS BIOTECHNOLOGY CORPORATION
    Inventors: Weihsu Chen, Weili Yan, Kenya Toney, Gregory Conn, Frank Bedu-Addo, Leaf Huang
  • Patent number: 6841658
    Abstract: The invention is directed to methods for purifying Troponin I, particularly recombinant Tropnin I produced in a bacterial expression system. Recombinant Tropnin I can be advantageously purified after reversibly protecting the free sulfhydryl groups, e.g., by forming sulfates. In a specific example, Tropnin I reacted with sodium tetrafhionate yielded sulfitolyzed Tropnin I, which was purified by chromatography on an anion exchanger, followed by hydrophobic interaction chromatography. Facile deprotection of the sulfhydryl groups yields a highly purified product ready for refolding.
    Type: Grant
    Filed: November 30, 2001
    Date of Patent: January 11, 2005
    Assignee: Akzo Nobel NV
    Inventors: Gregory Conn, Brian Reardon, Xianfang Zeng, Chenming Zhang
  • Publication number: 20030138907
    Abstract: The invention is directed to methods for purifying Troponin I, particularly recombinant Troponin I produced in a bacterial expression system. Recombinant Troponin I can be advantageously purified after reversibly protecting the free sulfhydryl groups, e.g., by forming sulfates. In a specific example, Tropnin I reacted with sodium tetrafhionate yields sulfitolyzed Tropnin I, which was purified by chromatography on an anion exchanger, followed by hydrophobic interaction chromatography. Facile deprotection of the sulfhydryl groups yields a highly purified product ready for refolding.
    Type: Application
    Filed: November 4, 2002
    Publication date: July 24, 2003
    Inventors: Gregory Conn, Brian Reardon, Xianfang Zeng, Chenming Zhang
  • Publication number: 20030105017
    Abstract: The invention is directed to methods for purifying Troponin I, particularly recombinant Tropnin I produced in a bacterial expression system. Recombinant Tropnin I can be advantageously purified after reversibly protecting the free sulfhydryl groups, e.g., by forming sulfates. In a specific example, Tropnin I reacted with sodium tetrafhionate yielded sulfitolyzed Tropnin I, which was purified by chromatography on an anion exchanger, followed by hydrophobic interaction chromatography. Facile deprotection of the sulfhydryl groups yields a highly purified product ready for refolding.
    Type: Application
    Filed: September 26, 2002
    Publication date: June 5, 2003
    Inventors: Gregory Conn, Brian Reardon, Xianfang Zeng, Chenming Zhang
  • Publication number: 20020064835
    Abstract: The invention is directed to methods for purifying Troponin I, particularly recombinant Tropnin I produced in a bacterial expression system. Recombinant Tropnin I can be advantageously purified after reversibly protecting the free sulfhydryl groups, e.g., by forming sulfates. In a specific example, Tropnin I reacted with sodium tetrafhionate yielded sulfitolyzed Tropnin I, which was purified by chromatography on an anion exchanger, followed by hydrophobic interaction chromatography. Facile deprotection of the sulfhydryl groups yields a highly purified product ready for refolding.
    Type: Application
    Filed: July 10, 2001
    Publication date: May 30, 2002
    Applicant: Diosynth RTP, Inc.
    Inventors: Gregory Conn, Brian Reardon, Xianfang Zeng, Chenming Zhang
  • Patent number: 6393809
    Abstract: A motor-driven and controlled packaging machine for forming pouches from a web of material. The controls allow the machine to be run with either a continuously or intermittently advancing web. Seal bars are mounted on moveable carriages which move with the web as they form the seals. A web unwind is servo controlled to minimize the amount of festoon section needed when operating in intermittent mode. Each registration-related component of the machine has a dedicated sensor for independently registering each component with the web. Accordingly, the machine may regain registration with minimal web waste and can be quickly and easily repositioned for different pouch sizes.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: May 28, 2002
    Assignee: Klockner Bartelt, Inc.
    Inventors: James E. Todd, Thomas E. Brooker, Gregory A. Conn
  • Publication number: 20020055145
    Abstract: The invention is directed to methods for purifying Troponin I, particularly recombinant Tropnin I produced in a bacterial expression system. Recombinant Tropnin I can be advantageously purified after reversibly protecting the free sulfhydryl groups, e.g., by forming sulfates. In a specific example, Tropnin I reacted with sodium tetrafhionate yielded sulfitolyzed Tropnin I, which was purified by chromatography on an anion exchanger, followed by hydrophobic interaction chromatography. Facile deprotection of the sulfhydryl groups yields a highly purified product ready for refolding.
    Type: Application
    Filed: November 30, 2001
    Publication date: May 9, 2002
    Applicant: Diosynth RTP, Inc.
    Inventors: Gregory Conn, Brian Reardon, Xianfang Zeng, Chenming Zhang
  • Patent number: 6381919
    Abstract: A packaging machine for forming pouches from a web of material having web tension control. A second pair of infeed rolls allows web tension through a sealing section to be controlled. An unwind reel is power-driven according to downstream web demand to thereby minimize tension spikes through the infeed section. The power unwind further minimizes the amount of festoon area needed. An entire packaging machine may be provided using modules. The registration-related operations of each section are independently controlled so that each module need only coordinate input and/or output speeds with interfacing sections.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: May 7, 2002
    Assignee: Klockner-Bartelt, Inc.
    Inventors: James E. Todd, Thomas E. Brooker, Gregory A. Conn
  • Patent number: 6272815
    Abstract: A motor-driven and controlled packaging machine for forming pouches from a web of material. The controls allow the machine to be run with either a continuously or intermittently advancing web. Seal bars are mounted on moveable carriages which move with the web as they form the seals. A web unwind is servo controlled to minimize the amount of festoon section needed when operating in intermittent mode. Each registration-related component of the machine has a dedicated sensor for independently registering each component with the web. Accordingly, the machine may regain registration with minimal web waste and can be quickly and easily repositioned for different pouch sizes.
    Type: Grant
    Filed: November 3, 1998
    Date of Patent: August 14, 2001
    Assignee: Klockner-Bartelt, Inc.
    Inventors: James E. Todd, Thomas E. Brooker, Gregory A. Conn
  • Publication number: 20010010142
    Abstract: A packaging machine for forming pouches from a web of material having web tension control. A second pair of infeed rolls allows web tension through a sealing section to be controlled. An unwind reel is power-driven according to downstream web demand to thereby minimize tension spikes through the infeed section. The power unwind further minimizes the amount of festoon area needed. An entire packaging machine may be provided using modules. The registration-related operations of each section are independently controlled so that each module need only coordinate input and/or output speeds with interfacing sections.
    Type: Application
    Filed: March 15, 2001
    Publication date: August 2, 2001
    Applicant: Klockner-Bartelt, Inc.
    Inventors: James E. Todd, Thomas E. Brooker, Gregory A. Conn