Patents by Inventor Gregory Endress
Gregory Endress has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20070020724Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: July 9, 2004Publication date: January 25, 2007Inventors: Steven Ruben, Jian Ni, Craig Rosen, Ying-Fei Wei, Paul Young, Kimberly Florence, Daniel Soppet, Laurie Brewer, Gregory Endress, Kenneth Carter, Michael Mucenski, Reinhard Ebner, David LaFleur, Henrik Olsen, Yanggu Shi, Paul Moore, George Komatsoulis
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Publication number: 20070014787Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: March 15, 2006Publication date: January 18, 2007Applicant: Human Genome Sciences, Inc.Inventors: Steven Ruben, George Komatsoulis, D. Duan, Craig Rosen, Paul Moore, Yanggu Shi, David LaFleur, Reinhard Ebner, Henrik Olsen, Laurie Brewer, Kimberly Florence, Paul Young, Michael Mucenski, Gregory Endress, Daniel Soppet
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Publication number: 20060223077Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: September 20, 2005Publication date: October 5, 2006Applicant: Human Genome Sciences, Inc.Inventors: Jian Ni, Reinhard Ebner, David LaFleur, Paul Moore, Henrik Olsen, Craig Rosen, Steven Ruben, Daniel Soppet, Paul Young, Yanggu Shi, Kimberly Florence, Ying-Fei Wei, Charles Florence, Jing-Shan Hu, Yi Li, Hla Kyaw, Carrie Fischer, Ann Ferrie, Ping Fan, Ping Feng, Gregory Endress, Patrick Dillon, Kenneth Carter, Laurie Brewer, Guo-Liang Yu, Zhizhen Zeng, John Greene
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Publication number: 20060205654Abstract: The present invention relates to huXAG-1, huXAG-2 and huXAG-3 proteins which are novel human growth factors. In particular, isolated nucleic acid molecules are provided encoding the huXAG-1, huXAG-2 and huXAG-3 proteins. huXAG-1, huXAG-2 and huXAG-3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of huXAG-1, huXAG-2 or huXAG-3 activity. Also provided are diagnostic and therapeutic uses of huXAG-1. huXAG-2 and huXAG-3.Type: ApplicationFiled: March 7, 2006Publication date: September 14, 2006Applicant: Human Genome Sciences, Inc.Inventors: Guo-Liang Yu, Patrick Dillon, Reinhard Ebner, Gregory Endress
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Publication number: 20060188962Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.Type: ApplicationFiled: April 17, 2006Publication date: August 24, 2006Applicant: Human Genome Sciences, Inc.Inventors: Kenneth Carter, Ping Feng, Craig Rosen, Steven Ruben, Gregory Endress
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Publication number: 20060147982Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.Type: ApplicationFiled: March 2, 2006Publication date: July 6, 2006Applicant: Human Genome Sciences, Inc.Inventors: Steven Ruben, Craig Rosen, Kenneth Carter, Patrick Dillon, Gregory Endress, Guo-Liang Yu, Jian Ni, Ping Feng
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Patent number: 7060801Abstract: The present invention relates to huXAG-1, huXAG-2 and huXAG-3 proteins which are novel human growth factors. In particular, isolated nucleic acid molecules are provided encoding the huXAG-1, huXAG-2 and huXAG-3 proteins. huXAG-1, huXAG-2 and huXAG-3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of huXAG-1, huXAG-2 or huXAG-3 activity. Also provided are diagnostic and therapeutic uses of huXAG-1. huXAG-2 and huXAG-3.Type: GrantFiled: August 20, 2004Date of Patent: June 13, 2006Assignee: Human Genome Sciences, Inc.Inventors: Guo-Liang Yu, Patrick J. Dillon, Reinhard Ebner, Gregory A. Endress
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Patent number: 7053190Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.Type: GrantFiled: October 19, 2001Date of Patent: May 30, 2006Assignee: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, Craig A. Rosen, Carrie L. Fischer, Daniel R. Soppet, Kenneth C. Carter, Daniel P. Bednarik, Gregory A. Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul E. Young, John M. Greene, Ann M. Ferrie, Roxanne Duan, Jing-Shan Hu, Kimberly A. Florence, Henrik S. Olsen, Reinhard Ebner, Laurie A. Brewer, Yanggu Shi
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Publication number: 20060099575Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: September 12, 2001Publication date: May 11, 2006Inventors: Steven Ruben, Ann Ferrie, Craig Rosen, Kimberly Florence, Kenneth Carter, Daniel Soppet, Guo-Liang Yu, Charles Florence, Paul Young, Jian Ni, Gregory Endress, Ping Feng, Fouad Janat, Charles Birse
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Publication number: 20060084082Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: June 6, 2005Publication date: April 20, 2006Applicant: Human Genome Sciences, Inc.Inventors: Steven Ruben, Craig Rosen, Daniel Soppet, Kenneth Carter, Daniel Bednarik, Gregory Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul Young, John Greene, Ann Ferrie, D. Duan, Jing-Shan Hu, Kimberly Florence, Henrik Olsen, Carrie Fischer, Reinhard Ebner, Laurie Brewer, Paul Moore, Yanggu Shi, David LaFleur, Yi Li, ZhiZhen Zeng, Hla Kyaw
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Publication number: 20060079670Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: September 20, 2005Publication date: April 13, 2006Applicant: Human Genome Sciences, Inc.Inventors: George Komatsoulis, Craig Rosen, Steven Ruben, Roxanne Duan, Paul Moore, Yanggu Shi, David LaFleur, Ying-Fei Wei, Jian Ni, Kimberly Florence, Paul Young, Laurie Brewer, Daniel Soppet, Gregory Endress, Reinhard Ebner, Henrik Olsen, Michael Mucenski
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Patent number: 7001992Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.Type: GrantFiled: February 5, 2002Date of Patent: February 21, 2006Assignee: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, Craig A. Rosen, Gregory A. Endress
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Publication number: 20060025574Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.Type: ApplicationFiled: September 15, 2005Publication date: February 2, 2006Applicant: Human Genome Sciences, Inc.Inventors: Steven Ruben, Craig Rosen, Kenneth Carter, Patrick Dillon, Gregory Endress, Guo-Liang Yu, Jian Ni, Ping Feng
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Publication number: 20050239059Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: September 12, 2001Publication date: October 27, 2005Inventors: Steven Ruben, Ann Ferrie, Craig Rosen, Kimberly Florence, Kenneth Carter, Daniel Soppet, Guo-Liang Yu, Charles Florence, Paul Young, Jian Ni, Gregory Endress, Ping Feng, Fouad Janat, Charles Birse
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Patent number: 6953667Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: GrantFiled: January 25, 2002Date of Patent: October 11, 2005Assignee: Human Genome Sciences, Inc.Inventors: Paul A. Moore, Steven M. Ruben, Henrik S. Olsen, Yanggu Shi, Craig A. Rosen, Kimberly A. Florence, Daniel R. Soppet, David W. LaFleur, Gregory A. Endress, Reinhard Ebner, George Komatsoulis, Roxanne D. Duan
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Publication number: 20050215775Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.Type: ApplicationFiled: November 2, 2004Publication date: September 29, 2005Applicant: Human Genome Sciences, Inc.Inventors: Steven Ruben, Craig Rosen, Carrie Fischer, Daniel Soppet, Kenneth Carter, Daniel Bednarik, Gregory Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul Young, John Greene, Ann Ferrie, D. Duan, Jing-Shan Hu, Kimberly Florence, Henrik Olsen, Reinhard Ebner, Laurie Brewer, Yanggu Shi
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Publication number: 20050095612Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.Type: ApplicationFiled: June 15, 2004Publication date: May 5, 2005Applicant: Human Genome Sciences, Inc.Inventors: Steven Ruben, Paul Young, Laurie Brewer, Reinhard Ebner, Henrik Olsen, Kimberly Florence, Craig Rosen, Roxanne Duan, Paul Moore, Yanggu Shi, David LaFleur, Charles Florence, Daniel Soppet, Gregory Endress, Ping Feng, George Komatsoulis
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Publication number: 20050069943Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.Type: ApplicationFiled: November 3, 2004Publication date: March 31, 2005Applicant: Human Genome Sciences, Inc.Inventors: Roxanne Duan, Steven Ruben, Kimberly Florence, John Greene, Craig Rosen, Paul Young, Ann Ferrie, Guo-Liang Yu, Fouad Janat, Jian Ni, Kenneth Carter, Gregory Endress, Ping Feng, David LaFleur, Yanggu Shi
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Publication number: 20050064454Abstract: Processes for assaying potential antitumor agents based on their modulation of the expression of specified genes, or sets, of suspected cancer cell genes are disclosed, along with methods for diagnosing cancerous, or potentially cancerous, conditions as a result of the expression, or patterns of expression, of such genes, or sets of genes. Also disclosed are methods for determining functionally related genes, or gene sets, as well as methods for treating cancer based on targeting expression products of such genes, or gene sets, and determining genes involved in the cancerous process.Type: ApplicationFiled: May 11, 2004Publication date: March 24, 2005Inventors: Paul Young, Meena Augustus, Kenneth Carter, Reinhard Ebner, Gregory Endress, Stephen Horrigan, Daniel Soppet, Zoe Weaver
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Publication number: 20050037467Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: September 9, 2004Publication date: February 17, 2005Applicant: Human Genome Sciences, Inc.Inventors: Steven Ruben, Ping Feng, David LaFleur, Paul Moore, Yanggu Shi, Hla Kyaw, Yi Li, ZhiZhen Zeng, Kenneth Carter, Gregory Endress, Ying-Fei Wei, Ping Fan, Craig Rosen