Patents by Inventor Gregory Endress

Gregory Endress has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel human growth factors
    Publication number: 20050026254
    Abstract: The present invention relates to huXAG-1, huXAG-2 and huXAG-3 proteins which are novel human growth factors. In particular, isolated nucleic acid molecules are provided encoding the huXAG-1, huXAG-2 and huXAG-3 proteins. huXAG-1, huXAG-2 and huXAG-3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of huXAG-1, huXAG-2 or huXAG-3 activity. Also provided are diagnostic and therapeutic uses of huXAG-1. huXAG-2 and huXAG-3.
    Type: Application
    Filed: August 20, 2004
    Publication date: February 3, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Guo-Liang Yu, Patrick Dillon, Reinhard Ebner, Gregory Endress
  • 47 human secreted proteins
    Publication number: 20040253684
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: July 7, 2004
    Publication date: December 16, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Reinhard Ebner, Craig A. Rosen, Gregory A. Endress, Daniel R. Soppet, Jian Ni, Roxanne D. Duan, Paul A. Moore, Yanggu Shi, David W. LaFleur, Henrik S. Olsen, Kimberly A. Florence
  • Human growth factors
    Patent number: 6818412
    Abstract: The present invention relates to huXAG-1, huXAG-2 and huXAG-3 proteins which are novel human growth factors. In particular, isolated nucleic acid molecules are provided encoding the huXAG-1, huXAG-2 and huXAG-3 proteins. huXAG-1, huXAG-2 and huXAG-3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of huXAG-1, huXAG-2 or huXAG-3 activity. Also provided are diagnostic and therapeutic uses of huXAG-1. huXAG-2 and huXAG-3.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: November 16, 2004
    Assignee: Human Genome Sciences, Inc.
    Inventors: Guo-Liang Yu, Patrick J. Dillon, Reinhard Ebner, Gregory A. Endress
  • Prostate derived Ets factor
    Publication number: 20040197345
    Abstract: The present invention relates to a novel human protein called Prostate Derived Ets Factor, and isolated polynucleotides encoding this protein. Also provided are vectors, host cells, antibodies, and recombinant methods for producing this human protein. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to this novel human protein.
    Type: Application
    Filed: May 5, 2004
    Publication date: October 7, 2004
    Applicants: Human Genome Sciences, Inc., Beth Israel Deaconess Medical Center
    Inventors: Towia Aron Libermann, Joerg Peter Oettgen, Charles A. Kunsch, Gregory A. Endress, Craig A. Rosen
  • 125 human secreted proteins
    Publication number: 20040185440
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: March 28, 2001
    Publication date: September 23, 2004
    Inventors: Ping Feng, Steven M. Ruben, Craig A. Rosen, Reinhard Ebner, Henrik S. Olsen, Jian Ni, Ying-Fei Wei, Daniel R. Soppet, Paul A. Moore, Hla Kyaw, David W. LaFleur, Yanggu Shi, Fouad Janat, Gregory A. Endress, Kenneth C. Carter
  • 101 human secreted proteins
    Publication number: 20040157258
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: March 15, 2004
    Publication date: August 12, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Roxanne Duan, Steven M. Ruben, Kimberly A. Florence, John M. Greene, Craig A. Rosen, Paul Young, Ann M. Ferrie, Guo-Liang Yu, Fouad Janat, Jian Ni, Kenneth C. Carter, Gregory A. Endress, Ping Feng, David W. Lafleur, Yanggu Shi
  • 94 human secreted proteins
    Publication number: 20040146930
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: March 16, 2004
    Publication date: July 29, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Craig A. Rosen, Ying-Fei Wei, Paul Young, Kimberly Florence, Daniel R. Soppet, Laurie A. Brewer, Gregory A. Endress, Kenneth C. Carter, Michael Mucenski, Reinhard Ebner, David W. LaFleur, Henrik Olsen, Yanggu Shi, Paul A. Moore, George Komatsoulis
  • Cancer-linked genes as targets for chemotherapy
    Publication number: 20040072192
    Abstract: Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with processes for assaying potential antitumor agents based on their modulation of the expression of these cancer-linked genes. Also disclosed are antibodies that react with the disclosed polypeptides and methods of diagnosing and treating cancer using the gene sequences. A novel gene and polypeptide are also disclosed.
    Type: Application
    Filed: October 15, 2003
    Publication date: April 15, 2004
    Inventors: Paul E Young, Stephen K Horrigan, Zoe Weaver, Gregory Endress
  • 31 human secreted proteins
    Publication number: 20040048294
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: June 27, 2003
    Publication date: March 11, 2004
    Applicant: Human Genome Sciences,Inc.
    Inventors: Steven M. Ruben, Craig A. Rosen, Roxanne D. Duan, Yanggu Shi, David W. LaFleur, Paul E. Young, Jian Ni, George Komatsoulis, Gregory A. Endress, Daniel R. Soppet
  • 95 human secreted proteins
    Publication number: 20040048304
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: September 3, 2003
    Publication date: March 11, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Craig A. Rosen, Guo-Liang Yu, Paul Young, Ping Feng, Daniel R. Soppet, Ying-Fei Wei, Gregory A. Endress, Roxanne Duan, Hla Kyaw, Reinhard Ebner, David W. LaFleur, Henrik Olsen, Yanggu Shi, Paul A. Moore
  • 125 human secreted proteins
    Publication number: 20040038277
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: July 18, 2003
    Publication date: February 26, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Craig A. Rosen, Ping Feng, Steven M. Ruben, Reinhard Ebner, Henrik Olsen, Jian Ni, Ying-Fei Wei, Daniel R. Soppet, Paul A. Moore, Hla Kyaw, David W. LaFleur, Yanggu Shi, Fouad Janat, Gregory A. Endress, Kenneth C. Carter, Charles E. Birse
  • 19 human secreted proteins
    Publication number: 20040024192
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: May 23, 2003
    Publication date: February 5, 2004
    Inventors: Kenneth C. Carter, Ping Feng, Craig A. Rosen, Steven M. Ruben, Gregory A. Endress
  • HUMAN PROTEIN HFXJW48
    Publication number: 20040014954
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: May 15, 2002
    Publication date: January 22, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Paul E. Young, Laurie A. Brewer, Reinhard Ebner, Henrik S. Olsen, Kimberly A. Florence, Craig A. Rosen, Roxanne D. Duan, Paul A. Moore, Yanggu Shi, David W. LaFleur, Charles Florence, Daniel R. Soppet, Gregory A. Endress, Ping Feng, George A. Komatsoulis
  • 186 human secreted proteins
    Publication number: 20030225248
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: June 10, 2002
    Publication date: December 4, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Craig A. Rosen, Daniel R. Soppet, Kenneth C. Carter, Daniel P. Bednarik, Gregory A. Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul E. Young, John M. Greene, Ann M. Ferrie, Roxanne Duan, Jing-Shan Hu, Kimberly A. Florence, Henrik S. Olsen, Carrie L. Fischer, Reinhard Ebner, Laurie A. Brewer, Paul A. Moore, Yanggu Shi, David W. LaFleur, Yi Li, Zhizhen Zeng, Hla Kyaw
  • 125 human secreted proteins
    Publication number: 20030211472
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: March 28, 2001
    Publication date: November 13, 2003
    Inventors: Ping Feng, Steven M. Ruben, Craig A. Rosen, Reinhard Ebner, Henrik S. Olsen, Jian Ni, Ying-Fei Wei, Daniel R. Soppet, Paul A. Moore, Hla Kyaw, David W. LaFleur, Yanggu Shi, Fouad Janat, Gregory A. Endress, Kenneth C. Carter
  • 83 human secreted proteins
    Publication number: 20030199683
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: March 30, 2001
    Publication date: October 23, 2003
    Inventors: Steven M. Ruben, Ping Feng, David W. LaFleur, Paul A. Moore, Yanggu Shi, Hla Kyaw, Yi Li, Zhizhen Zeng, Kenneth C. Carter, Gregory A. Endress, Ying-Fei Wei, Ping Fan, Craig A. Rosen
  • Secreted protein HEMCM42
    Publication number: 20030195346
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: February 5, 2002
    Publication date: October 16, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Craig A. Rosen, Kenneth C. Carter, Patrick J. Dillon, Gregory A. Endress, Guo-Liang Yu, Jian Ni, Ping Feng
  • Antibodies to secreted protein HCEJQ69
    Patent number: 6627741
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: September 30, 2003
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Craig A. Rosen, Ying-Fei Wei, Paul Young, Kimberly Florence, Daniel R. Soppet, Laurie A. Brewer, Gregory A. Endress, Kenneth C. Carter, Michael Mucenski, Reinhard Ebner, David W. LaFleur, Henrik Olsen, Yanggu Shi, Paul A. Moore, George Komatsoulis
  • 207 human secreted proteins
    Publication number: 20030181692
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: August 22, 2001
    Publication date: September 25, 2003
    Inventors: Jian Ni, Reinhard Ebner, David W. LaFleur, Paul A. Moore, Henrik S. Olsen, Craig A. Rosen, Steven M. Ruben, Daniel R. Soppet, Paul E. Young, Yanggu Shi, Kimberly A. Florence, Ying-Fei Wei, Charles Florence, Jing-Shan Hu, Yi Li, Hla Kyaw, Carrie L. Fischer, Ann M. Ferrie, Ping Fan, Ping Feng, Gregory A. Endress, Patrick J. Dillon, Kenneth C. Carter, Laurie A. Brewer, Guo-Liang Yu, Zhizhen Zeng, John M. Greene
  • 186 human secreted proteins
    Publication number: 20030175858
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: June 18, 2001
    Publication date: September 18, 2003
    Inventors: Steven M. Ruben, Craig A. Rosen, Daniel R. Soppet, Kenneth C. Carter, Daniel P. Bednarik, Gregory A. Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul E. Young, John M. Greene, Ann M. Ferrie, D. Roxanne Duan, Jing-Shan Hu, Kimberly A. Florence, Henrik S. Olsen, Carrie L. Fischer, Reinhard Ebner, Laurie A. Brewer, Paul A. Moore, Yanggu Shi, David W. LaFleur, Yi Li, ZhiZhen Zeng, Hla Kyaw