Patents by Inventor Gregory Frost
Gregory Frost has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210118434Abstract: A system, method, and computer program product for determining statement attributions. The system includes at least one processing component, at least one memory component, a feature extractor, a model generator, a model database, and an attribution selector. The method includes receiving a statement, generating at least one pattern that defines a grammatical feature of the statement, and generating a statement model from the at least one pattern. The method also includes determining a similarity value for the statement model and at least one reference model.Type: ApplicationFiled: October 16, 2019Publication date: April 22, 2021Inventors: Stephen Arthur Boxwell, Keith Gregory Frost, Kyle Matthew Brake, Stanley John Vernier
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Patent number: 10936264Abstract: A method, computer program product and computer system to improve print legibility is provided. A processor receives a file to print. A processor generates a print preview of the file, wherein the print preview is generated at an initial scale. A processor generates a preview text for the print preview. A processor determines a legibility metric based for the print preview on a comparison between the preview text for the print preview and text of the file to print. A processor prints the file at a second scale in response to the legibility metric being below a predetermined value, wherein the second scale is larger than the initial scale.Type: GrantFiled: August 16, 2019Date of Patent: March 2, 2021Assignee: International Business Machines CorporationInventors: Stanley John Vernier, Stephen Arthur Boxwell, Kyle Matthew Brake, Keith Gregory Frost
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Patent number: 10929076Abstract: A method, computer program product and computer system to improve print legibility is provided. A processor receives a file to print. A processor generates a print preview of the file, wherein the print preview is generated at an initial scale. A processor generates a preview text for the print preview. A processor determines a legibility metric based for the print preview on a comparison between the preview text for the print preview and text of the file to print. A processor prints the file at a second scale in response to the legibility metric being below a predetermined value, wherein the second scale is larger than the initial scale.Type: GrantFiled: June 20, 2019Date of Patent: February 23, 2021Assignee: International Business Machines CorporationInventors: Stanley John Vernier, Stephen Arthur Boxwell, Kyle Matthew Brake, Keith Gregory Frost
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Publication number: 20200401466Abstract: Methods, systems and computer program products for facilitating real time conversations based on topic determination are provided. Aspects include receiving one or more user topic profiles. Aspects also include receiving an audio recording of a conversation obtained from one or more audio sensors. Aspects also include converting the audio recording of the conversation to text. Aspects also include determining a topic of the conversation by applying a topic model to the text. Aspects also include determining one or more potentially interested users based on the topic of the conversation and the one or more user topic profiles. Aspects also include notifying the one or more potentially interested users that the conversation is occurring.Type: ApplicationFiled: June 20, 2019Publication date: December 24, 2020Inventors: Keith Gregory FROST, Stephen Arthur BOXWELL, Stanley John VERNIER, Kyle Matthew BRAKE
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Publication number: 20200401358Abstract: A method, computer program product and computer system to improve print legibility is provided. A processor receives a file to print. A processor generates a print preview of the file, wherein the print preview is generated at an initial scale. A processor generates a preview text for the print preview. A processor determines a legibility metric based for the print preview on a comparison between the preview text for the print preview and text of the file to print. A processor prints the file at a second scale in response to the legibility metric being below a predetermined value, wherein the second scale is larger than the initial scale.Type: ApplicationFiled: June 20, 2019Publication date: December 24, 2020Inventors: Stanley John Vernier, Stephen Arthur Boxwell, Kyle Matthew Brake, Keith Gregory Frost
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Publication number: 20200401359Abstract: A method, computer program product and computer system to improve print legibility is provided. A processor receives a file to print. A processor generates a print preview of the file, wherein the print preview is generated at an initial scale. A processor generates a preview text for the print preview. A processor determines a legibility metric based for the print preview on a comparison between the preview text for the print preview and text of the file to print. A processor prints the file at a second scale in response to the legibility metric being below a predetermined value, wherein the second scale is larger than the initial scale.Type: ApplicationFiled: August 16, 2019Publication date: December 24, 2020Inventors: Stanley John Vernier, Stephen Arthur Boxwell, Kyle Matthew Brake, Keith Gregory Frost
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Publication number: 20200365186Abstract: An embodiment of the invention may include a method, computer program product and computer system for video editing. The method, computer program product and computer system may include computing device which may receive video data from an imaging device, the video data may include visual and audio data. The computing device may convert the audio data to text and parse the text into textual segments. The computing device may annotate the textual segments with time stamps and analyze the annotated textual segments to identify pre-determined edit commands. The computing device may generate an edit script based on the identified pre-determined edit commands in the textual segments.Type: ApplicationFiled: May 15, 2019Publication date: November 19, 2020Inventors: Keith Gregory Frost, Stephen Arthur Boxwell, Stanley John Vernier, Kyle Matthew Brake
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Patent number: 10832733Abstract: An embodiment of the invention may include a method, computer program product and computer system for video editing. The method, computer program product and computer system may include computing device which may receive video data from an imaging device, the video data may include visual and audio data. The computing device may convert the audio data to text and parse the text into textual segments. The computing device may annotate the textual segments with time stamps and analyze the annotated textual segments to identify pre-determined edit commands. The computing device may generate an edit script based on the identified pre-determined edit commands in the textual segments.Type: GrantFiled: May 15, 2019Date of Patent: November 10, 2020Assignee: International Business Machines CorporationInventors: Keith Gregory Frost, Stephen Arthur Boxwell, Stanley John Vernier, Kyle Matthew Brake
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Patent number: 10811051Abstract: An embodiment of the invention may include a method, computer program product and computer system for video editing. The method, computer program product and computer system may include computing device which may receive video data from an imaging device, the video data may include visual and audio data. The computing device may convert the audio data to text and parse the text into textual segments. The computing device may annotate the textual segments with time stamps and analyze the annotated textual segments to identify pre-determined edit commands. The computing device may generate an edit script based on the identified pre-determined edit commands in the textual segments.Type: GrantFiled: July 11, 2019Date of Patent: October 20, 2020Assignee: International Business Machines CorporationInventors: Keith Gregory Frost, Stephen Arthur Boxwell, Stanley John Vernier, Kyle Matthew Brake
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Publication number: 20200226135Abstract: Embodiments of the present invention are directed to a computer-implemented method for determining topic specific reliability for a question answering system. A non-limiting example of the computer-implemented method includes receiving a topic specific input query by the question answering system. The method further includes detecting a source that provides a reference containing the ground truth answers to the ground truth questions. The method further includes traversing sources detect similar references in other sources and assigning reliability scores for each source based upon ground truth answers in the other sources. The method further includes providing a ranked list of answers based upon the reliability of each source upon for each answer.Type: ApplicationFiled: January 16, 2019Publication date: July 16, 2020Inventors: Keith Gregory Frost, Stanley John Vernier, Kyle Matthew Brake, Stephen Arthur Boxwell
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Publication number: 20200218988Abstract: A computer-implemented method includes generating from a corpus a knowledge graph comprising a plurality of nodes interconnected by a plurality of edges. Each node of the plurality of nodes represents an entity extracted from the corpus. Each edge of the plurality of edges represents a relationship between corresponding entities extracted from the corpus. The knowledge graph includes a plurality of source passages extracted from the corpus from which the plurality of edges was generated. A generative language model is trained, for each edge of the plurality of edges, to associate two or more related entities by utilizing the knowledge graph. Using the trained generative language model, one or more passages representing the edge of the knowledge graph are generated for each edge of the knowledge graph.Type: ApplicationFiled: January 8, 2019Publication date: July 9, 2020Inventors: STEPHEN ARTHUR BOXWELL, KYLE MATTHEW BRAKE, STANLEY JOHN VERNIER, KEITH GREGORY FROST
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Publication number: 20200159757Abstract: A computer-implemented method includes receiving a plurality of question, answer, passage (QAP) triples. Each of the plurality of QAP triples includes a question, an answer to the question and a passage containing the answer to the question. The received plurality of QAP triples is parsed to generate two or more patterns. The generated patterns are merged together to identify clusters of semantically related patterns.Type: ApplicationFiled: November 19, 2018Publication date: May 21, 2020Inventors: STEPHEN ARTHUR BOXWELL, KEITH GREGORY FROST, STANLEY JOHN VERNIER, KYLE MATTHEW BRAKE
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Publication number: 20200159824Abstract: Embodiments relate to an intelligent computer platform to provide a contextual response to an interrogatory. An electronic communication interface or portal is dynamically evaluated by an artificial intelligence (AI) platform. Natural language processing (NLP) is utilized to detect and evaluate a communication, identify an interrogatory within the communication, and determine an intent of the interrogatory. A corresponding factoid pipeline is searched for content related to the intent, and a response to the interrogatory is ascertained, formulated, and presented to the electronic communication interface.Type: ApplicationFiled: November 15, 2018Publication date: May 21, 2020Applicant: International Business Machines CorporationInventors: Stephen Arthur Boxwell, Keith Gregory Frost, Stanley John Vernier, Kyle Matthew Brake
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Publication number: 20120164127Abstract: This disclosure relates to a method of generating conditionally active biologic proteins from wild type proteins, in particular therapeutic proteins, which are reversibly or irreversibly inactivated at the wild type normal physiological conditions. For example, evolved proteins are virtually inactive at body temperature, but are active at lower temperatures.Type: ApplicationFiled: March 9, 2010Publication date: June 28, 2012Inventors: Jay M. Short, Hwai Wen Chang, Gerhard Frey, Gregory Frost
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Publication number: 20110229451Abstract: Provided are modified matrix metalloprotease (MMP) enzymes that exhibit temperature-dependent activity and uses thereof. The MMPs can be used, for example, to treat ECM-mediated diseases or disorders characterized by increased deposition or accumulation of one or more ECM components.Type: ApplicationFiled: March 5, 2010Publication date: September 22, 2011Applicant: HALOZYME, INC.Inventors: Louis Bookbinder, Gregory Frost, Gilbert Keller, Gerhard Frey, Hwai Chang, Jay Short
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Publication number: 20070148156Abstract: The invention relates to the discovery of a novel Chondroitinase Glycoproteins (CHASEGP's), methods of manufacture, and potential uses in conditions where removal of chondroitin sulfates may be of therapeutic benefit. Chondroitinase Glycoproteins require both a substantial portion of the catalytic domain of the CHASEGP polypeptide and asparagine-linked glycosylation for optimal chondroitinase activity. The invention also includes carboxy-terminal deletion variants of CHASEGP that result in secreted variants of the protein to facilitate manufacture of a recombinant CHASEGP. Further described are suitable formulations of a substantially purified recombinant CHASEGP glycoprotein derived from a eukaryotic cell that generate the proper glycosylation required for its optimal activity. CHASEGP is useful for the degradation of glycosaminoglycans and chondroitin sulfate proteoglycans under clinical conditions where their removal is of therapeutic value.Type: ApplicationFiled: December 15, 2003Publication date: June 28, 2007Inventors: Gregory Frost, Anirban Kundu, Louis Bookbinder
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Publication number: 20070134228Abstract: The invention is based on the discovery of methods for purification of an acid active hyaluronidase found in human plasma (hpHAse), including both biochemical and immunoaffinity purification methods The method of immunoaffinity purification of the invention is based on the discovery of a method for identifying antibodies that specifically bind native hpHAse (anti-native hpHAse antibodies), and anti-native hpHAse antibodies identified by this screening method. The invention also features an assay for sensitive detection of HAse activity using biotinylated hyaluronic acid (bHA). Purification and characterization of hpHAse lead to the inventors' additional discovery that hpHAse is encoded by the LuCa-1 gene, which gene is present in the human chromosome at 3p21.3, a region associated with tumor suppression. The invention additionally features methods of treating tumor-bearing patients by administration of hpHAse and/or transformation of cells with hpHAse-encoding DNA.Type: ApplicationFiled: October 3, 2006Publication date: June 14, 2007Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Robert STERN, Gregory FROST, Anthony CSOKA, Tim Wong
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Publication number: 20060247201Abstract: The identification of the HYAL1 hyaluronidase enzyme as a human plasma-derived myeloid colony-stimulating factor (CSF), herein designated CSF5-hyaluronidase, its recombinant production and methods of use are described. This protein may be used for the treatment of myelosuppression as may occur after irradiation, chemotherapy or other diseases where an increase in leukocyte levels may be beneficial. For example, CSF5- may be used to enhance the immune response to viral infection or other diseases associated with immune suppression.Type: ApplicationFiled: May 9, 2006Publication date: November 2, 2006Inventors: Gregory Frost, Per Borgstrom
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Publication number: 20060242915Abstract: A synthetic resin article is provided for use in a fluid diversion system with one or more distribution lines. The article's frame has a top, at least one side, a bottom and an interior. At least one aperture is formed at the top. An intake port is disposed on at least one side of the frame, for engagement with the system distribution line. A drainage structure is disposed on the bottom of the frame for downward drainage of standing water into the surrounding soil or other environment. When the system delivers fluid through the distribution line, it is received in the interior of the frame and drains slowly out through the drainage structure but normally when the system delivers fluid to the interior at a sufficient rate, the fluid rises to the top of the frame and percolates out of the outlet aperture. In preferred embodiments, the top includes a plurality of small outlet gratings for additional percolation.Type: ApplicationFiled: April 29, 2005Publication date: November 2, 2006Inventor: Gregory Frost
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Publication number: 20060104968Abstract: The invention relates to the discovery of novel soluble neutral active Hyaluronidase Glycoproteins (sHASEGPs), methods of manufacture, and their use to facilitate administration of other molecules or to alleviate glycosaminoglycan associated pathologies. Minimally active polypeptide domains of the soluble, neutral active sHASEGP domains are described that include asparagine-linked sugar moieties required for a functional neutral active hyaluronidase domain. Included are modified amino-terminal leader peptides that enhance secretion of sHASEGP. The invention further comprises sialated and pegylated forms of a recombinant sHASEGP to enhance stability and serum pharmacokinetics over naturally occurring slaughterhouse enzymes. Further described are suitable formulations of a substantially purified recombinant sHASEGP glycoprotein derived from a eukaryotic cell that generate the proper glycosylation required for its optimal activity.Type: ApplicationFiled: September 27, 2005Publication date: May 18, 2006Applicant: Halozyme, Inc.Inventors: Louis Bookbinder, Anirban Kundu, Gregory Frost, Michael Haller, Gilbert Keller, Tyler Dylan