Abstract: An irradiation device includes a fluid treatment chamber configured to receive a biological fluid container, the fluid treatment chamber having opposing first and second sides, at least one light source disposed adjacent at least one of the first and second sides of the fluid treatment chamber, and an overflow reservoir in fluid communication with the fluid treatment chamber to receive fluid leaking from the biological fluid container. The device also includes a non-contact sensor disposed adjacent the overflow reservoir and configured to generate a signal according to leaked fluid in the overflow reservoir, an indicator, and a controller coupled to the at least one light source, the non-contact sensor and the indicator, the controller configured to activate the indicator upon receipt of the signal from the sensor and to deactivate the at least one light source subsequent to receipt of the signal from the sensor.

Abstract: A dispenser includes a housing having a cavity. A container is provided within the cavity and includes a volatile material therein. The dispenser further includes a resistive heating wire. The container is in thermal communication with at least a portion of the resistive heating wire.

Abstract: A fluid circuit for use with a fluid processing assembly, the fluid circuit comprising an umbilicus having a first end, a second end, an axis of rotation, and a cross-sectional circumference; a one-piece bearing secured to the umbilicus at a location between the first and second ends, the bearing having an axis of rotation and including an inner lumen which directly engages the umbilicus and includes a plurality of traction features, which bear against the umbilicus to prevent relative rotation of the bearing and the umbilicus; and the plurality of traction features comprising a first traction feature configured to engage the umbilicus at a first set of lengths between the first and second ends and a second traction feature configured to engage the umbilicus at a second set of lengths between the first and second ends.

Abstract: A fluid circuit for use with a fluid processing assembly, the fluid circuit comprising an umbilicus having a first end, a second end, an axis of rotation, and a cross-sectional circumference; a one-piece bearing secured to the umbilicus at a location between the first and second ends, the bearing having an axis of rotation and including an inner lumen which directly engages the umbilicus and includes a plurality of traction features, which bear against the umbilicus to prevent relative rotation of the bearing and the umbilicus; and the plurality of traction features comprising a first traction feature configured to engage the umbilicus at a first set of lengths between the first and second ends and a second traction feature configured to engage the umbilicus at a second set of lengths between the first and second ends.

Abstract: A device for irradiation of a biological product/substance is provided comprising a base; a tray having a first and second side associated with the base and configured to receive a container holding the biological product/substance to be irradiated; a first array of radiation-emitting bulbs mounted in the device adjacent the first side of the tray; a second array of radiation-emitting bulbs mounted in device adjacent a second side of the tray; a first filter mounted in the device between the tray and the first array of radiation-emitting bulbs for blocking and/or reflecting radiation emitted by the first array of a selected wavelength; and a second filter mounted in the device beneath the second array of radiation-emitting bulbs for blocking and/or reflecting radiation emitted by the second array of the selected wavelength.

Abstract: An irradiation device includes a fluid treatment chamber configured to receive a biological fluid container, the fluid treatment chamber having opposing first and second sides, at least one light source disposed adjacent at least one of the first and second sides of the fluid treatment chamber, and an overflow reservoir in fluid communication with the fluid treatment chamber to receive fluid leaking from the biological fluid container. The device also includes a non-contact sensor disposed adjacent the overflow reservoir and configured to generate a signal according to leaked fluid in the overflow reservoir, an indicator, and a controller coupled to the at least one light source, the non-contact sensor and the indicator, the controller configured to activate the indicator upon receipt of the signal from the sensor and to deactivate the at least one light source subsequent to receipt of the signal from the sensor.

Abstract: A fluid circuit for use with a fluid processing assembly, the fluid circuit comprising an umbilicus having a first end, a second end, an axis of rotation, and a cross-sectional circumference; a one-piece bearing secured to the umbilicus at a location between the first and second ends, the bearing having an axis of rotation and including an inner lumen which directly engages the umbilicus and includes a plurality of traction features, which bear against the umbilicus to prevent relative rotation of the bearing and the umbilicus; and the plurality of traction features comprising a first traction feature configured to engage the umbilicus at a first length between the first and second ends and a second traction feature configured to engage the umbilicus at a second length between the first and second ends.

Abstract: A fluid circuit for use with a fluid processing assembly, the fluid circuit comprising an umbilicus having a first end, a second end, an axis of rotation, and a cross-sectional circumference; a one-piece bearing secured to the umbilicus at a location between the first and second ends, the bearing having an axis of rotation and including an inner lumen which directly engages the umbilicus and includes a plurality of traction features, which bear against the umbilicus to prevent relative rotation of the bearing and the umbilicus; and the plurality of traction features comprising a first traction feature configured to engage the umbilicus at a first length between the first and second ends and a second traction feature configured to engage the umbilicus at a second length between the first and second ends.

Abstract: Fluid separation chambers are provided for rotation about an axis in a fluid processing system. The fluid separation chamber may be provided with first and second stages, with the first and second stages being positioned at different axial locations. In another embodiment, at least one of the stages may be provided with a non-uniform outer diameter about the rotational axis, which may define a generally spiral-shaped profile or a different profile for fractionating a fluid or fluid component. One or more of the stages may also have a varying outer diameter along the axis. The profile of the chamber may be provided by the chamber itself (in the case of rigid chambers) or by an associated fixture or centrifuge apparatus (in the case of flexible chambers).

Abstract: A drive assembly for a centrifugal processing system is provided for rotating the yoke assembly (36) about a first axis at a first angular velocity and rotating the chamber assembly (30) coaxially with the yoke assembly at a second angular velocity A drive motor (60) is provided for rotating the yoke assembly at the first angular velocity A stationary gear (70) is mounted coaxially with the yoke assembly, with a drive linkage (72) comprising a shaft (74) secured to the yoke assembly so as to be rotatable therewith. The shaft is operatively connected on its first end to the stationary gear (70), so that the shaft rotates about its axis as the yoke assembly (36) rotates relative to the stationary gear. The shaft (74) is rotatably connected on its second end to the chamber assembly (30), so that when the shaft is rotated, the shaft rotates the chamber assembly.

Abstract: A drive assembly for a centrifugal processing system is provided for rotating the yoke assembly (36) about a first axis at a first angular velocity and rotating the chamber assembly (30) coaxially with the yoke assembly at a second angular velocity A drive motor (54) is provided for rotating the yoke assembly at the first angular velocity and simultaneously rotating the chamber assembly at the second angular velocity by a sun gear (66) mounted to the chamber assembly for rotation about the first axis and a planetary gear (64) mounted to the yoke assembly that is operatively connected to the sun gear such as to impart rotation to the sun gear as it orbits thereabout upon rotation of the yoke assembly.

Abstract: Fluid separation chambers are provided for rotation about an axis in a fluid processing system. The fluid separation chamber may be provided with first and second stages, with the first and second stages being positioned at different axial locations. In another embodiment, at least one of the stages may be provided with a non-uniform outer diameter about the rotational axis, which may define a generally spiral-shaped profile or a different profile for fractionating a fluid or fluid component. One or more of the stages may also have a varying outer diameter along the axis. The profile of the chamber may be provided by the chamber itself (in the case of rigid chambers) or by an associated fixture or centrifuge apparatus (in the case of flexible chambers).

Abstract: A sheeting is provided for use with a fluid processing cassette having a valve station with a plurality of fluid flow ports. The sheeting has a generally flexible layer and a biasing member associated with the layer. The sheeting is attached to the cassette such that the biasing member is received within the valve station. The cassette may be used with a fluid processing system having a valve actuator with a piston that is aligned with the cassette during use. In an extended position, the piston presses the sheeting against the port to prevent fluid flow through the valve station. When the piston moves from the extended position to a retracted position, it allows the sheeting to uncover the port, thereby allowing fluid flow through the valve station. The biasing member assists in displacing the sheeting from the port when the piston moves to the retracted position.

Abstract: A drive assembly for a centrifugal processing system is provided for rotating the yoke assembly (36) about a first axis at a first angular velocity and rotating the chamber assembly (30 coaxially with the yoke assembly at a second angular velocity A drive motor (54) is provided for rotating the yoke assembly at the first angular velocity and simultaneously rotating the chamber assembly at the second angular velocity by means of a stationary first gear (64), a second gear (68) mounted to the yoke assembly that operatively engages the first gear, a third gear (74) rotatably mounted to the yoke assembly so as to synchronously rotate with the second gear, and a fourth gear (76) fixed to the chamber assembly that operatively engages the third gear so as to rotate the chamber assembly (30) relative to the yoke assembly (36) upon rotation of the yoke assembly about the first gear.

Abstract: A clamping apparatus is provided for use with a fluid flow device, such as a blood separation system. The clamping apparatus includes a clamp head at least partially defining first and second tube openings each to receive tubing. The clamping apparatus also includes a first actuator coupled to a first flow control member. The first flow control member is configured to be movable via the first actuator relative to the first tube opening to control fluid flow through tubing located in the first tube opening. The clamping apparatus further includes a second actuator coupled to a second flow control member. The second flow control member is movable via the second actuator relative to the second tube opening to control fluid flow through tubing located in the second tube opening.

Abstract: An umbilicus for use in an umbilicus-drive fluid processing centrifuge system is disclosed, together with a method of making it and a fluid flow circuit including such umbilicus. The umbilicus includes an elongated umbilicus body, a first end fitting defining an interior cavity, an adapter received within the interior cavity and having at least one port extension extending into a fluid transmitting lumen of the umbilicus body, the adapter and end fitting including interfering surfaces to enhance torque resistance therebetween.

Abstract: A drive assembly for a centrifugal processing system is provided for rotating the yoke assembly (36) about a first axis at a first angular velocity and rotating the chamber assembly (30 coaxially with the yoke assembly at a second angular velocity A drive motor (54) is provided for rotating the yoke assembly at the first angular velocity and simultaneously rotating the chamber assembly at the second angular velocity by means of a stationary first gear (64), a second gear (68) mounted to the yoke assembly that operatively engages the first gear, a third gear (74) rotatably mounted to the yoke assembly so as to synchronously rotate with the second gear, and a fourth gear (76) fixed to the chamber assembly that operatively engages the third gear so as to rotate the chamber assembly (30) relative to the yoke assembly (36) upon rotation of the yoke assembly about the first gear.

Abstract: A drive assembly for a centrifugal processing system is provided for rotating the yoke assembly (36) about a first axis at a first angular velocity and rotating the chamber assembly (30) coaxially with the yoke assembly at a second angular velocity A drive motor (54) is provided for rotating the yoke assembly at the first angular velocity and simultaneously rotating the chamber assembly at the second angular velocity by means of a sun gear (66) mounted to the chamber assembly for rotation about the first axis and a planetary gear (64) mounted to the yoke assembly that is operatively connected to the sun gear such as to impart rotation to the sun gear as it orbits thereabout upon rotation of the yoke assembly.

Abstract: A drive assembly for a centrifugal processing system is provided for rotating the yoke assembly (36) about a first axis at a first angular velocity and rotating the chamber assembly (30) coaxially with the yoke assembly at a second angular velocity A drive motor (60) is provided for rotating the yoke assembly at the first angular velocity A stationary gear (70 is mounted coaxially with the yoke assembly, with a drive linkage (72) comprising a shaft (74) secured to the yoke assembly so as to be rotatable therewith. The shaft is operatively connected on its first end to the stationary gear (70), so that the shaft rotates about its axis as the yoke assembly (36) rotates relative to the stationary gear. The shaft (74) is rotatably connected on its second end to the chamber assembly (30), so that when the shaft is rotated, the shaft rotates the chamber assembly.