Patents by Inventor Gregory M. Whited

Gregory M. Whited has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220411301
    Abstract: The present disclosure is generally related to the fields of biology, inorganic chemistry, organic chemistry, molecular biology, enzymology, chlorinated water treatment processes and the like. More particularly, certain embodiments are related to reducing cyanuric acid concentrations in aqueous liquids, such as chlorinated swimming pool water, chlorinated hot tub water and the like.
    Type: Application
    Filed: October 14, 2020
    Publication date: December 29, 2022
    Inventors: Kelly Gardner Aukema, Rajdeep S. Dhaliwal, Feng Guo, Meng Hong Heng, Katherine Hoffman, Jacob Andrew Latone, Lawrence Philip Wackett, Gregory M. Whited
  • Publication number: 20220389474
    Abstract: The present disclosure is generally related to the fields of biology, molecular biology, genetics, microbial host cells, industrial enzyme production, and the like. More particularly, certain embodiments of the disclosure are related to microbial host cells for the production of heterologous proteins, which microbial host cells are well-suited for growth in submerged cultures for the large-scale production of heterologous cyanuric acid hydrolases and biuret hydrolases.
    Type: Application
    Filed: October 14, 2020
    Publication date: December 8, 2022
    Inventors: Sharief Barends, Cristina Bongiorni, Feng Guo, Lori Ann Maggio-Hall, Lawrence Philip Wackett, Gregory M. Whited
  • Publication number: 20220331219
    Abstract: Compositions comprising mevalonolactone, mevalonic add, mevalonate, salts of mevalonic acid, mevalonolactone monohydrate, or any combination thereof and methods of use are provided for topical application for skin care, skin supplement, hair care, and oral care. More specifically, the present disclosure is directed towards compositions comprising mevalonolactone, mevalonic acid, mevalonate, salts of mevalonic acid, mevalonolactone monohydrate, or any combination thereof for providing a skin care benefit and/or multiple skin care benefits.
    Type: Application
    Filed: August 25, 2020
    Publication date: October 20, 2022
    Inventors: Heli ANGLENIUS, Carole GHERARDI, Laura Tiina Maria HUUSKONEN, Juho JÄRVINEN, Henrik Max JENSEN, Hannu KOIVIKKO, Jyrki KUUSISTO, Tero Tuomas MENTUNEN, Juha NURMI, Piera Mattia PERICU, Pertti Matias SÄRELÄ, Jani SIITONEN, Kirsti TIIHONEN, Gregory M. WHITED
  • Publication number: 20220324786
    Abstract: Compositions and methods are provided for producing crystalline forms of organic acids or salts or lactones thereof from an aqueous solution. More specifically, methods are provided for producing a crystalline form of a salt of mevalonic acid (also referred to as X-MVA) from an aqueous solution, comprising subjecting the aqueous solution comprising said X-MVA to a purification step to produce a purified solution and crystallizing said X-MVA from said purified solution by water solvent crystallization. Methods are also provided for producing mevalonolactone from an aqueous solution comprising X-MVA, comprising subjecting the aqueous solution comprising said X-MVA to cation exchange thereby converting said aqueous solution comprising X-MVA to an aqueous solution comprising mevalonolactone (MVL). Methods are also provided for producing mevalonolactone monohydrate crystals.
    Type: Application
    Filed: August 25, 2020
    Publication date: October 13, 2022
    Inventors: Juho JÄRVINEN, Hannu KOIVIKKO, Jyrki KUUSISTO, Tero Tuomas MENTUNEN, Juha NURMI, Pertti Matias SÄRELÄ, Jani SIITONEN, Gregory M. WHITED
  • Patent number: 10774345
    Abstract: The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a non-flammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity.
    Type: Grant
    Filed: August 15, 2017
    Date of Patent: September 15, 2020
    Assignees: Danisco US Inc., The Goodyear Tire & Rubber Company
    Inventors: Anthony R. Calabria, Marguerite A. Cervin, Gopal K. Chotani, Richard La Duca, Joseph C. McAuliffe, Michael C. Miller, Timothy A. Sabo, Karl J. Sanford, Erin. L. Spring, Gregory M. Whited
  • Patent number: 10626420
    Abstract: The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: April 21, 2020
    Assignees: Danisco US Inc., The Goodyear Tire & Rubber Company
    Inventors: Marguerite A. Cervin, Gopal K. Chotani, Frank J. Feher, Richard La Duca, Joseph C. McAuliffe, Andrei Miasnikov, Caroline M. Peres, Aaron S. Puhala, Karl J. Sanford, Fernando Valle, Gregory M. Whited
  • Publication number: 20180273982
    Abstract: The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells.
    Type: Application
    Filed: January 17, 2018
    Publication date: September 27, 2018
    Applicants: Danisco US Inc., The Goodyear Tire & Rubber Company
    Inventors: Marguerite A. CERVIN, Gopal K. CHOTANI, Frank J. FEHER, Richard LA DUCA, Joseph C. MCAULIFFE, Andrei MIASNIKOV, Caroline M. PERES, Aaron S. PUHALA, Karl J. SANFORD, Fernando VALLE, Gregory M. WHITED
  • Publication number: 20180066287
    Abstract: The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a non-flammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity.
    Type: Application
    Filed: August 15, 2017
    Publication date: March 8, 2018
    Inventors: Anthony R. CALABRIA, Marguerite A. CERVIN, Gopal K. CHOTANI, Richard LA DUCA, Joseph C. MCAULIFFE, Michael C. MILLER, Timothy A. SABO, Karl J. SANFORD, Erin L. Spring, Gregory M. WHITED
  • Patent number: 9909144
    Abstract: The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells.
    Type: Grant
    Filed: January 4, 2016
    Date of Patent: March 6, 2018
    Assignees: Danisco US Inc., The Goodyear Tire & Rubber Company
    Inventors: Marguerite A. Cervin, Gopal K. Chotani, Frank J. Feher, Richard La Duca, Joseph C. McAuliffe, Andrei Miasnikov, Caroline M. Peres, Aaron S. Puhala, Karl J. Sanford, Fernando Valle, Gregory M. Whited
  • Patent number: 9777294
    Abstract: The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a non-flammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: October 3, 2017
    Assignees: Danisco US Inc., The Goodyear Tire & Rubber Company
    Inventors: Anthony R. Calabria, Marguerite A. Cervin, Gopal K. Chotani, Richard La Duca, Joseph C. McAuliffe, Michael C. Miller, Timothy A. Sabo, Karl J. Sanford, Erin L. Spring, Gregory M. Whited
  • Publication number: 20160281113
    Abstract: The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells.
    Type: Application
    Filed: January 4, 2016
    Publication date: September 29, 2016
    Inventors: Marguerite A. Cervin, Gopal K. Chotani, Frank J. Feher, Richard La Duca, Joseph C. McAuliffe, Andrei Miasnikov, Caroline M. Peres, Aaron S. Puhala, Karl J. Sanford, Fernando Valle, Gregory M. Whited
  • Publication number: 20160281112
    Abstract: The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a nonflammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity.
    Type: Application
    Filed: December 17, 2015
    Publication date: September 29, 2016
    Inventors: Anthony R. CALABRIA, Marguerite A. CERVIN, Gopal K. CHOTANI, Richard LA DUCA, Joseph C. MCAULIFFE, Michael C. MILLER, Timothy A. SABO, Karl J. SANFORD, Erin L. WEBSTER, Gregory M. WHITED
  • Patent number: 9296850
    Abstract: It has been found that certain cells in culture can convert more than about 0.002 percent of the carbon available in the cell culture medium into isoprene. These cells have a heterologous nucleic acid that (i) encodes an isoprene synthase polypeptide and (ii) is operably linked to a promoter. The isoprene produced in such a cultured medium can then be recovered and polymerized into synthetic rubbers and other useful polymeric materials. The synthetic isoprene containing polymers of this invention offer the benefit of being verifiable as to being derived from non-petrochemical based resources. They can also be analytically distinguished from rubbers that come from natural sources. The present invention more specifically discloses a polyisoprene polymer which is comprised of repeat units that are derived from isoprene monomer, wherein the polyisoprene polymer has ?13C value of greater than ?22%.
    Type: Grant
    Filed: January 26, 2015
    Date of Patent: March 29, 2016
    Assignees: The Goodyear Tire & Rubber Company, Danisco US, Inc.
    Inventors: Frank J. Feher, Gregory M. Whited, Gopal K. Chotani, Fernando Valle, Carol Fioresi, Karl J. Sanford, Joseph McAuliffe, Marguerite Cervin, Aaron S. Puhala, Andrei Miasnikov, Ilana S. Aldor
  • Patent number: 9282746
    Abstract: The present invention provides methods and compositions comprising at least one perhydrolase enzyme for cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions for generation of peracids. The present invention finds particular use in applications involving cleaning, bleaching and disinfecting.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: March 15, 2016
    Assignee: Danisco US Inc.
    Inventors: Neelam S. Amin, Matthew G. Boston, Richard R. Bott, Maguerite A. Cervin, Edward M. Concar, Marc E. Gustwiller, Brian E. Jones, Klaus Liebeton, Gregory S. Miracle, Hiroshi Oh, Ayrookaran J. Poulose, Sandra W. Ramer, Jeffrey J. Scheibel, Walter Weyler, Gregory M. Whited
  • Patent number: 9260727
    Abstract: The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells.
    Type: Grant
    Filed: August 30, 2012
    Date of Patent: February 16, 2016
    Assignees: DANISCO US INC., THE GOODYEAR TIRE & RUBBER COMPANY
    Inventors: Marguerite A. Cervin, Gopal K. Chotani, Frank J. Feher, Richard La Duca, Joseph C. McAuliffe, Andrei Miasnikov, Caroline M. Peres, Aaron S. Puhala, Karl J. Sanford, Fernando Valle, Gregory M. Whited
  • Patent number: 9249070
    Abstract: The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a nonflammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity.
    Type: Grant
    Filed: May 20, 2013
    Date of Patent: February 2, 2016
    Assignees: DANISCO US INC., THE GOODYEAR TIRE & RUBBER COMPANY
    Inventors: Anthony R. Calabria, Marguerite A. Cervin, Gopal K. Chotani, Richard La Duca, Joseph C. McAuliffe, Michael C. Miller, Timothy A. Sabo, Karl J. Sanford, Erin L. Spring, Gregory M. Whited
  • Publication number: 20160002672
    Abstract: The invention provides for compositions and methods for the production of isoprene, isoprenoid precursor, and/or isoprenoids in cells via the expression (e.g., heterologous expression) of phosphomevalonate decarboxylases and/or isopentenyl kinases.
    Type: Application
    Filed: December 20, 2013
    Publication date: January 7, 2016
    Inventors: Zachary Q. BECK, Jörg MAMPEL, Guido MEURER, Michael C. MILLER, Karl J. SANFORD, Dmitrii V. VAVILINE, Walter WEYLER, Gregory M. WHITED
  • Patent number: 9121039
    Abstract: The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells. The invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity. Additionally, the invention provides methods of producing isoprene by culturing cells under conditions suitable for isoprene production while maintaining cell viability and/or metabolic activity.
    Type: Grant
    Filed: September 16, 2013
    Date of Patent: September 1, 2015
    Assignees: Danisco US Inc., The Goodyear Tire & Rubber Company
    Inventors: Gopal K. Chotani, Joseph C. McAuliffe, Caroline M. Peres, Gregory M. Whited
  • Publication number: 20150203620
    Abstract: It has been found that certain cells in culture can convert more than about 0.002 percent of the carbon available in the cell culture medium into isoprene. These cells have a heterologous nucleic acid that (i) encodes an isoprene synthase polypeptide and (ii) is operably linked to a promoter. The isoprene produced in such a cultured medium can then be recovered and polymerized into synthetic rubbers and other useful polymeric materials. The synthetic isoprene containing polymers of this invention offer the benefit of being verifiable as to being derived from non-petrochemical based resources. They can also be analytically distinguished from rubbers that come from natural sources. The present invention more specifically discloses a polyisoprene polymer which is comprised of repeat units that are derived from isoprene monomer, wherein the polyisoprene polymer has ?13C value of greater than ?22%.
    Type: Application
    Filed: January 26, 2015
    Publication date: July 23, 2015
    Applicants: DANISCO US INC., THE GOODYEAR TIRE & RUBBER COMPANY
    Inventors: Frank J. Feher, Gregory M. Whited, Gopal K. Chotani, Fernando Valle, Carol Fioresi, Karl J. Sanford, Joseph McAuliffe, Marguerite Cervin, Aaron S. Puhala, Andrei Miasnikov, Ilana S. Aldor
  • Publication number: 20150191712
    Abstract: The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved catalytic activity and/or solubility. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in microbial host cells. Biosynthetically produced isoprene of the present invention finds use in the manufacture of rubber and elastomers.
    Type: Application
    Filed: November 17, 2014
    Publication date: July 9, 2015
    Inventors: Richard R. BOTT, Marguerite A. Cervin, James T. Kellis, JR., Joseph C. Mcauliffe, Andrei Miasnikov, Caroline M. Peres, Christopher L. Rife, Derek H. Wells, Walter Weyler, Gregory M. Whited