Patents by Inventor Gregory M. Whited
Gregory M. Whited has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150118211Abstract: The invention provides methods, compositions, and kits for removal of biofilms from surfaces. The methods described herein comprise simultaneous or sequential application of a perhydrolase enzyme and a mixture of other enzymes, such as proteases, glucanases, esterases, mannanases, phospholipases, cellulases, and/or amylases, to a biofilm on a surface, to effect removal of the biofilm.Type: ApplicationFiled: November 1, 2013Publication date: April 30, 2015Applicant: Danisco US Inc.Inventors: Christopher C. Barnett, Manoj Kumar, Gregory M. Whited
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Patent number: 8940849Abstract: It has been found that certain cells in culture can convert more than about 0.002 percent of the carbon available in the cell culture medium into isoprene. These cells have a heterologous nucleic acid that (i) encodes an isoprene synthase polypeptide and (ii) is operably linked to a promoter. The isoprene produced in such a cultured medium can then be recovered and polymerized into synthetic rubbers and other useful polymeric materials. The synthetic isoprene containing polymers of this invention offer the benefit of being verifiable as to being derived from non-petrochemical based resources. They can also be analytically distinguished from rubbers that come from natural sources. The present invention more specifically discloses a polyisoprene polymer which is comprised of repeat units that are derived from isoprene monomer, wherein the polyisoprene polymer has ?13C value of greater than ?22‰.Type: GrantFiled: March 11, 2013Date of Patent: January 27, 2015Assignees: The Goodyear Tire & Rubber Company, Danisco US Inc.Inventors: Frank J. Feher, Gregory M. Whited, Gopal K. Chotani, Fernando Valle, Carol Fioresi, Karl J. Sanford, Joseph McAuliffe, Marguerite Cervin, Aaron S. Puhala, Andrei Miasnikov, Ilana S. Aldor
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Patent number: 8916370Abstract: The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved catalytic activity and/or solubility. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in microbial host cells. Biosynthetically produced isoprene of the present invention finds use in the manufacture of rubber and elastomers.Type: GrantFiled: March 30, 2012Date of Patent: December 23, 2014Assignees: Danisco US Inc., The Goodyear Tire & Rubber CompanyInventors: Richard R. Bott, Marguerite A. Cervin, James T. Kellis, Jr., Joseph C. McAuliffe, Andrei Miasnikov, Caroline M. Peres, Christopher Lee Rife, Derek H. Wells, Walter Weyler, Gregory M. Whited
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Patent number: 8906658Abstract: The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a non-flammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity.Type: GrantFiled: January 14, 2013Date of Patent: December 9, 2014Assignees: Danisco US Inc., The Goodyear Tire & Rubber CompanyInventors: Anthony R. Calabria, Marguerite A. Cervin, Gopal K. Chotani, Richard La Duca, Joseph C. McAuliffe, Michael C. Miller, Timothy A. Sabo, Karl J. Sanford, Erin L. Spring, Gregory M. Whited
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Publication number: 20140302003Abstract: The present invention provides methods and compositions comprising at least one perhydrolase enzyme for cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions for generation of peracids. The present invention finds particular use in applications involving cleaning, bleaching and disinfecting.Type: ApplicationFiled: May 8, 2014Publication date: October 9, 2014Applicant: DANISCO US INC.Inventors: Neelam S. Amin, Matthew G. Boston, Richard R. Bott, Maguerite A. Cervin, Edward M. Concar, Marc E. Gustwiller, Brian E. Jones, Klaus Liebeton, Gregory S. Miracle, Hiroshi Oh, Ayrookaran J. Poulose, Sandra W. Ramer, Jeffrey J. Scheibel, Walter Weyler, Gregory M. Whited
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Publication number: 20140234926Abstract: This invention provides for recombinant anaerobic acetogenic bacterial cells having one or more nucleic acids whereby isoprene, mevalonate and/or other industrial bio-products are produced in a substantially oxygen-free culture condition using synthesis gas as energy and/or carbon source.Type: ApplicationFiled: November 27, 2013Publication date: August 21, 2014Applicants: E I Du Pont De Nemours And Company, The Goodyear Tire And Rubber Company, Danisco US IncInventors: ZACHARY Q. BECK, Marguerite A. Cervin, Gopal K. Chotani, Bruce A. Diner, Janine Fan, Caroline M. Peres, Karl J. Sanford, Miles C. Scotcher, Derek H. Wells, Gregory M. Whited
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Patent number: 8772007Abstract: The present invention provides methods and compositions comprising at least one perhydrolase enzyme for cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions for generation of peracids. The present invention finds particular use in applications involving cleaning, bleaching and disinfecting.Type: GrantFiled: December 3, 2004Date of Patent: July 8, 2014Assignee: Danisco US Inc.Inventors: Neelam S. Amin, Matthew G. Boston, Richard R. Bott, Marguerite A. Cervin, Edward M. Concar, Marc E. Gustwiller, Brian E. Jones, Klaus Liebeton, Gregory S. Miracle, Hiroshi Oh, Ayrookaran J. Poulose, Sandra W. Ramer, Jeffrey J. Scheibel, Walter Weyler, Gregory M. Whited
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Publication number: 20140155660Abstract: The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a non-flammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity.Type: ApplicationFiled: May 20, 2013Publication date: June 5, 2014Applicants: The Goodyear Tire & Rubber Company, Danisco US Inc.Inventors: Anthony R. Calabria, Marguerite A. Cervin, Gopal K. Chotani, Richard La Duca, Joseph C. McAuliffe, Michael C. Miller, Timothy A. Sabo, Karl J. Sanford, Erin L. Spring, Gregory M. Whited
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Publication number: 20140128645Abstract: The invention provides for methods for the production of isoprene in recombinant marine bacterial cells via the heterologous expression of isoprene synthase enzymes.Type: ApplicationFiled: December 20, 2012Publication date: May 8, 2014Applicants: The Goodyear Tire & Rubber Company, DANISCO US INC.Inventors: Richard LA DUCA, Karl J. SANFORD, Gregory M. WHITED
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Patent number: 8709785Abstract: The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells.Type: GrantFiled: August 30, 2012Date of Patent: April 29, 2014Assignees: Danisco US Inc., The Goodyear Tire & Rubber CompanyInventors: Marguerite A. Cervin, Gopal K. Chotani, Frank J. Feher, Richard La Duca, Joseph C. McAuliffe, Andrei Miasnikov, Caroline M. Peres, Aaron S. Puhala, Karl J. Sanford, Fernando Valle, Gregory M. Whited
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Publication number: 20140085998Abstract: The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal-containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate.Type: ApplicationFiled: August 23, 2013Publication date: March 27, 2014Applicant: Danisco US Inc.Inventors: Richard R. Bott, Rasmus B. Jensen, Bradley R. Kelemen, Donald E. Ward II, Gregory M. Whited
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Publication number: 20140073026Abstract: The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells. The invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity. Additionally, the invention provides methods of producing isoprene by culturing cells under conditions suitable for isoprene production while maintaining cell viability and/or metabolic activity.Type: ApplicationFiled: September 16, 2013Publication date: March 13, 2014Applicants: THE GOODYEAR TIRE & RUBBER COMPANY, DANISCO US INC.Inventors: Gopal K. CHOTANI, Joseph C. MCAULIFFE, Caroline M. PERES, Gregory M. WHITED
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Patent number: 8597927Abstract: The invention provides methods, compositions, and kits for removal of biofilms from surfaces. The methods described herein comprise simultaneous or sequential application of a perhydrolase enzyme and a mixture of other enzymes, such as proteases, glucanases, esterases, mannanases, phospholipases, cellulases, and/or amylases, to a biofilm on a surface, to effect removal of the biofilm.Type: GrantFiled: December 16, 2008Date of Patent: December 3, 2013Assignee: Danisco US Inc.Inventors: Christopher C. Barnett, Manoj Kumar, Gregory M. Whited
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Patent number: 8569026Abstract: The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells. The invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity. Additionally, the invention provides methods of producing isoprene by culturing cells under conditions suitable for isoprene production while maintaining cell viability and/or metabolic activity.Type: GrantFiled: September 15, 2009Date of Patent: October 29, 2013Assignees: Danisco US Inc., The Goodyear Tire & Rubber CompanyInventors: Gopal K. Chotani, Joseph C. McAuliffe, Caroline M. Peres, Gregory M. Whited
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Publication number: 20130260432Abstract: The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved catalytic activity and/or solubility. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in microbial host cells. Biosynthetically produced isoprene of the present invention finds use in the manufacture of rubber and elastomers.Type: ApplicationFiled: March 30, 2012Publication date: October 3, 2013Applicant: Danisco US Inc.Inventors: Richard R. BOTT, Marguerite A. Cervin, James T. Kellis, JR., Joseph C. McAuliffe, Andrei Miasnikov, Caroline M. Peres, Christopher Lee Rife, Derek H. Wells, Walter Weyler, Gregory M. Whited
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Publication number: 20130253141Abstract: It has been found that certain cells in culture can convert more than about 0.002 percent of the carbon available in the cell culture medium into isoprene. These cells have a heterologous nucleic acid that (i) encodes an isoprene synthase polypeptide and (ii) is operably linked to a promoter. The isoprene produced in such a cultured medium can then be recovered and polymerized into synthetic rubbers and other useful polymeric materials. The synthetic isoprene containing polymers of this invention offer the benefit of being verifiable as to being derived from non-petrochemical based resources. They can also be analytically distinguished from rubbers that come from natural sources. The present invention more specifically discloses a polyisoprene polymer which is comprised of repeat units that are derived from isoprene monomer, wherein the polyisoprene polymer has ?13C value of greater than ?22‰.Type: ApplicationFiled: March 11, 2013Publication date: September 26, 2013Applicants: DANISCO US INC., THE GOODYEAR TIRE & RUBBER COMPANYInventors: Frank J. Feher, Gregory M. Whited, Gopal K. Chotani, Fernando Valle, Carol Fioresi, Karl J. Sanford, Joseph McAuliffe, Marguerite Cervin, Aaron S. Puhala, Andrei Miasnikov, Ilana S. Aldor
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Patent number: 8476041Abstract: A method is disclosed for restoring a Glu+ phenotype to a PTS?/Glu? bacterial cell which was originally capable of utilizing a phosphotransferase transport system (PTS) for carbohydrate transport. Bacterial cells comprising the Glu+ phenotype have modified endogenous chromosomal regulatory regions which are operably linked to polynucleotides encoding galactose permeases and glucokinases.Type: GrantFiled: May 14, 2012Date of Patent: July 2, 2013Assignee: Danisco US Inc.Inventors: Marguerite A. Cervin, Philippe Soucaille, Fernando Valle, Gregory M. Whited
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Patent number: 8420759Abstract: It has been found that certain cells in culture can convert more than about 0.002 percent of the carbon available in the cell culture medium into isoprene. These cells have a heterologous nucleic acid that (i) encodes an isoprene synthase polypeptide and (ii) is operably linked to a promoter. The isoprene produced in such a cultured medium can then be recovered and polymerized into synthetic rubbers and other useful polymeric materials. The synthetic isoprene containing polymers of this invention offer the benefit of being verifiable as to being derived from non-petrochemical based resources. They can also be analytically distinguished from rubbers that come from natural sources. The present invention more specifically discloses a polyisoprene polymer which is comprised of repeat units that are derived from isoprene monomer, wherein the polyisoprene polymer has ?13C value of greater than ?22‰.Type: GrantFiled: June 30, 2009Date of Patent: April 16, 2013Assignees: The Goodyear Tire & Rubber Company, Danisco US, Inc.Inventors: Frank J. Feher, Gregory M. Whited, Gopal K. Chotani, Fernando Valle, Carol Fioresi, Karl J. Sanford, Joseph C. McAuliffe, Marguerite Cervin, Aaron S. Puhala, Andrei Miasnikov, Ilana S. Aldor
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Patent number: 8420360Abstract: The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a non-flammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity.Type: GrantFiled: July 1, 2009Date of Patent: April 16, 2013Assignees: Danisco US Inc., The Goodyear Tire & Rubber CompanyInventors: Anthony R. Calabria, Marguerite A. Cervin, Gopal K. Chotani, Richard La Duca, Joseph C. McAuliffe, Michael C. Miller, Timothy A. Sabo, Karl J. Sanford, Erin L. Webster, Gregory M. Whited
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Publication number: 20130078699Abstract: The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells.Type: ApplicationFiled: August 30, 2012Publication date: March 28, 2013Applicants: The Goodyear Tire & Rubber Company, Danisco US Inc.Inventors: Marguerite A. CERVIN, Gopal K. Chotani, Frank J. Feher, Richard La Duca, Joseph C. McAuliffe, Andrei Miasnikov, Caroline M. Peres, Aaron S. Puhala, Karl J. Sanford, Fernando Valle, Gregory M. Whited