Patents by Inventor Gromoslaw A. Smolen

Gromoslaw A. Smolen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200032353
    Abstract: The present invention provides a novel method to determine the likelihood of effectiveness of a treatment in an individual affected with or at risk for developing cancer. The method involves detecting the presence or absence of Met amplification in an individual. The presence of Met amplification indicates that a Met targeting treatment is likely to be effective. Preferably, the Met targeting treatment is PHA-665752 or PF-02341066. In addition, the present methods allow for the detection of cancer in an individual, wherein the presence of Met amplification indicates that cancer is present and further that it will be treatable, namely with a Met targeting treatment.
    Type: Application
    Filed: October 9, 2019
    Publication date: January 30, 2020
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: Daniel A. Haber, Gromoslaw A. Smolen
  • Publication number: 20140162277
    Abstract: The present invention provides a novel method to determine the likelihood of effectiveness of a treatment in an individual affected with or at risk for developing cancer. The method involves detecting the presence or absence of Met amplification in an individual. The presence of Met amplification indicates that a Met targeting treatment is likely to be effective. Preferably, the Met targeting treatment is PHA-665752 or PF-02341066. In addition, the present methods allow for the detection of cancer in an individual, wherein the presence of Met amplification indicates that cancer is present and further that it will be treatable, namely with a Met targeting treatment.
    Type: Application
    Filed: November 22, 2013
    Publication date: June 12, 2014
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: Daniel A. Haber, Gromoslaw A. Smolen
  • Patent number: 8652786
    Abstract: The present invention provides a novel method to determine the likelihood of effectiveness of a treatment in an individual affected with or at risk for developing cancer. The method involves detecting the presence or absence of Met amplification in an individual. The presence of Met amplification indicates that a Met targeting treatment is likely to be effective. Preferably, the Met targeting treatment is PHA-665752 or PF-02341066. In addition, the present methods allow for the detection of cancer in an individual, wherein the presence of Met amplification indicates that cancer is present and further that it will be treatable, namely with a Met targeting treatment.
    Type: Grant
    Filed: April 5, 2006
    Date of Patent: February 18, 2014
    Assignee: The General Hospital Corporation
    Inventors: Daniel A. Haber, Gromoslaw A. Smolen
  • Publication number: 20080220424
    Abstract: The present invention provides a novel method to determine the likelihood of effectiveness of a treatment in an individual affected with or at risk for developing cancer. The method involves detecting the presence or absence of Met amplification in an individual. The presence of Met amplification indicates that a Met targeting treatment is likely to be effective. Preferably, the Met targeting treatment is PHA-665752 or PF-02341066. In addition, the present methods allow for the detection of cancer in an individual, wherein the presence of Met amplification indicates that cancer is present and further that it will be treatable, namely with a Met targeting treatment.
    Type: Application
    Filed: April 5, 2006
    Publication date: September 11, 2008
    Applicant: The General Hospital Corporation
    Inventors: Daniel A. Haber, Gromoslaw A. Smolen
  • Publication number: 20060246492
    Abstract: The present invention provides a novel method to determine the likelihood of effectiveness of a treatment in an individual affected with or at risk for developing cancer. The method involves detecting the presence or absence of Met amplification in an individual. The presence of Met amplification indicates that a Met targeting treatment is likely to be effective. Preferably, the Met targeting treatment is PHA-665752 or PF-02341066. In addition, the present methods allow for the detection of cancer in an individual, wherein the presence of Met amplification indicates that cancer is present and further that it will be treatable, namely with a Met targeting treatment.
    Type: Application
    Filed: April 5, 2006
    Publication date: November 2, 2006
    Applicant: The General Hospital Corporation
    Inventors: Daniel Haber, Gromoslaw Smolen