Abstract: The present invention provides compounds of any one of Formulae (A), (I-11), (II), and (V) (e.g., compounds of Formula (A-1)-(A-18)), and methods for treating Waldenström's macroglobulinemia (WM) and other B cell neoplams in a subject using the compounds. The methods comprise administering to a subject in need thereof an effective amount of the compounds. Also provided are methods to treat B cell neoplasms using the compounds in combination with inhibitors of Bruton's tyrosine kinase (BTK), interleukin-1 receptor-associated kinase 1 (IRAK1), interleukin-1 receptor-associated kinase 4 (IRAK4), bone marrow on X chromosome kinase (BMX), phosphoinositide 3-kinase (PI3K), transforming growth factor b-activated kinase-1 (TAK1), and/or a Src family kinase.

Abstract: A voltage detector comprising, a first voltage reference generator for generating a first voltage reference signal; a second voltage reference generator for generating a second voltage reference signal, wherein the second voltage reference signal is higher than the first voltage reference signal; a trigger, powered by an input signal to the voltage detector, and having an input for receiving either the first or second voltage reference signal and an output for generating a detection signal; and a switch for selectively connecting the input of the trigger to the first or second voltage reference signal, wherein the switch is operative to connect the input of the trigger to the first voltage reference signal when the detection signal output by the voltage detector is low and is operative to connect the input of the trigger to the second voltage reference signal when the detection signal output by the voltage detector is high, and a voltage detector system for monitoring an input signal and outputting a detectio

Abstract: Driving parameters (e.g., speed, heading direction) that an autonomous driving vehicle (ADV) likely utilize as target driving parameters are grouped into a number of ranges and one of the driving parameters in each range is selected as a driving parameter representative or a target driving parameter representing the respective range or segment. For each of the target driving parameters representing the ranges, a particle swarm optimization method is utilized to derive a set of most optimized coefficients for a controller (e.g., speed controller, steering controller) for controlling an ADV. A driving parameter to coefficient (parameter/coefficient) mapping table is generated to map a particular driving parameter representing a range of driving parameter to a set of one or more coefficients of a particular controller. The parameter/coefficient mapping table is utilized at real-time to configure a controller in response to a particular target driving parameter using the corresponding coefficients.

Abstract: The present invention is directed to compositions and methods for treating hepatitis B virus infection. In particular, the present invention is directed to a combination therapy comprising administration of an HBV capsid assembly inhibitor and an interferon for use in the treatment of hepatitis B virus infections.

Abstract: The present invention provides compounds of any one of Formulae (I) to (V) (e.g., compounds of any one of Formulae (I-1) to (I-9)), and methods for treating Waldenström's macroglobulinemia (WM) and other B cell neoplams in a subject using the compounds. The methods comprise administering to a subject in need thereof an effective amount of the compounds. Also provided are methods to treat B cell neoplasms using the compounds in combination with inhibitors of Bruton's tyrosine kinase (BTK), interleukin-1 receptor-associated kinase 1 (IRAK1), interleukin-1 receptor-associated kinase 4 (IRAK4), bone marrow on X chromosome kinase (BMX), phosphoinositide 3-kinase (PI3K), transforming growth factor b-activated kinase-1 (TAK1), and/or a Src family kinase.

Abstract: The present disclosure provides an access processing method, a base station and a mobile communication terminal. The access processing method includes: receiving an access request carrying a target NAS message from a mobile communication terminal capable of being connected to a first network and a second network, the target NAS message including a first NAS message corresponding to the first network and/or a second NAS message corresponding to the second network; determining a target core network, the target core network being a core network to which the base station is capable of accessing among a first core network corresponding to the first network and a second core network corresponding to the second network; and transmitting the target NAS message to the target core network.

Abstract: A method, device, and electronic terminal for video recording are provided. The method includes: receiving streaming data of a video, and decoding and broadcasting of the video on a webpage of a browser through a video-playing plugin; based on a triggering operation for starting video recording detected on the webpage by the browser, acquiring first image data and first audio data outputted by the video-playing plugin through a data interaction interface between the video-playing plugin and the browser; encoding the first image data and the first audio data to generate second image data and second audio data; synthesizing the second image data and the second audio data to generate and store streaming data of a recorded video.

Abstract: Examples of the present disclosure describe content creation of at least one abstract from extracted content. Input information is received that comprises a link to a landing page and keyword information. The landing page is evaluated and content including at least one of image data and text data is extracted from the landing page. Properties of the content extracted are analyzed. The content extracted is ranked based on the analyzed properties and application of at least two ranking algorithms. A first ranking algorithm applied ranks the content based on relevance to the landing page and a second ranking algorithm applied ranks the content extracted based on relevance to the keyword information. The ranked content is filtered to remove content or portions of content that are determined to be unappealing based on applying filtering rules to the ranked content. At least one abstract is created from the filtered and ranked content.

Abstract: A temperature sensor of a thermal monitoring system is provided for use in power distribution systems. The temperature sensor comprises ceramic printed circuit board (PCB) and a terminal. The ceramic PCB includes a temperature sensing element disposed on a side of the ceramic PCB. The terminal is configured to be fixed directly in contact with a measured point and is directly in touch with the ceramic PCB such that heat is conducted from the terminal, through the ceramic PCB and then to the temperature sensing element. The temperature sensing element is configured to generate an electrical signal in response to the heat such that the electrical signal is sent through a pair of lead wires to a controller for monitoring a temperature. The temperature sensor further comprises an epoxy to seal a portion of the terminal, the ceramic PCB in its entirety and a portion of the pair of lead wires to ensure a desired physical strength and a desired dielectric strength.

Abstract: When generating a control command of an autonomous driving vehicle (ADV), a pitch status and/or a roll status of the road is determined. The control command is adjusted based on the pitch status and the roll status. For example, when an ADV is driving on an uphill or downhill road, a pitch status of the road is determined and a speed control command will be generated based on the pitch status of the road, such that the ADV have a similar acceleration rate as of driving on a flat road. Similarly, when the ADV is driving on a road that is tilted or rolled left or right, a roll status of the road is determined and a steering control command will be generated in view of the roll status of the road, such that the ADV have a similar heading direction as of driving on a flat road.

Abstract: According to one embodiment, a content item is received that was searched and identified based on a first set of one or more keywords determined based on a search query received from a client device over a network. A search is performed in an image store to identify a plurality of images based on the first set of keywords and a second set of one or more keywords associated with the content item. The images are ranked based on a user context obtained at a time when the search query was received. A composite content item is generated by incorporating an image selected from the ranked images with the content item, where the selected image is ranked above a predetermined threshold. The composite content item is transmitted to the client device over the network.

Abstract: A lane departure detection system detects that an autonomous driving vehicle (ADV) is departing from the lane in which the ADV is driving based on sensor data captured when the ADV contact a deceleration curb such as a speed bump laid across the lane. When the ADV contacts the deceleration curb, the lane departure detection system detects and calculates an angle of a moving direction of the ADV vs a longitudinal direction of the deceleration curb. Based on the angle, the system calculates how much the moving direction of the ADV is off compared to a lane direction of the lane. The lane direction is typically substantially perpendicular to the longitudinal direction of the deceleration curb. A control command such as a speed control command and/or a steering control command is generated based on the angle to correct the moving direction of the ADV.

Abstract: A vehicle can include a traction battery and a controller in communication with the battery to determine the battery state using sensed battery electrode capacity to account for battery aging. The sensed battery electrode capacity can be dependent on active lithium ions at a positive electrode of the traction battery. The controller can compare a battery voltage model to measured battery voltage during a vehicle drive cycle, receive sensed current throughput data and open circuit voltage at the battery, and determine if a deviation threshold is exceeded. The controller can also correct electrode capacity using a mean of the measured open-circuit voltage to correct the capacity error to less than one amp-hour or initiate an active lithium capacity correction using a variance of the current throughput to correct the capacity error to less than one amp-hour. This information can be used to control the vehicle and battery usage.

Abstract: A voltage detector (200) for monitoring an input signal and outputting a detection signal at an output when a voltage of the input signal meets a first threshold having: an input configured for receiving the input signal; a voltage reference circuit for receiving an input voltage and producing a reference voltage having a maximum value independent of the input voltage; and a trigger configured to compare the input signal and the reference voltage and to output a detection signal to the output when the voltage of the input signal reaches the first threshold. The voltage reference circuit comprises a reset input connected to either the input or the output and is configured to reduce the reference voltage when a predetermined reset signal is received.

Abstract: In one embodiment, an autonomous driving vehicle (ADV) speed following system determines how much and when to apply a throttle or a brake control of an ADV to maneuver the ADV around, or to avoid, obstacles of a planned route. The speed following system calculates a first torque force to accelerate the ADV, a second torque force to counteract frictional forces and wind resistances to maintain a reference speed, and a third torque force to minimize an initial difference and external disturbances thereafter between predefined target speed and actual speed of the ADV over a planned route. The speed following system determines a throttle-brake torque force based on the first, second, and third torque forces and utilizes the throttle-brake torque force to control a subsequent speed of the ADV.

Abstract: Methods of treatment of conditions or diseases associated with myeloid differentiation primary response (MYD88) protein using a selective HCK inhibitor are provided herein.

Abstract: In one embodiment, it is determined that an ADV is about to decelerate based on perception of a driving environment surrounding the ADV. In addition, if there is another vehicle that is following the ADV, a distance between the ADV and the following vehicle, as well as the speed of the following vehicle, is determined. A deceleration rate that is required for the following vehicle to avoid a collision with the ADV is determined based on the distance between the ADV and the following vehicle and the speed of the following vehicle. If the deceleration rate is greater than a predetermined threshold, a brake light and an emergency light of the ADV are turned on to warn the following vehicle that the ADV is about to rapidly decelerate as it is treated as an emergency situation.

Abstract: With regard to a learning method for a smartwatch to prevent a metal hand from lightening the screen by unintended touch, a mainboard chip firstly finds and learns points which unintendedly touch the screen. Then, the mainboard chip reserves the time Tm which leads to unintended touch on the screen. The mainboard chip judges the present state: at the reserved time Tm, if the display screen is in an ON state, the display screen will keep the ON state. If the display screen is in an OFF state, the display screen will keep the OFF state.

Abstract: According to one embodiment, content keyword elements (CKEs) are determined based on content keywords (CKs) associated with content items. Query keyword elements (QKEs) are determined based on query keywords (QKs) associated with search queries. A first search query having one or more query keywords represented by a first QKE. A first content keyword represented by a first CKE that matches the first QKE is identified. A new entry in a query-to-CK (query/CK) whitelist table to map the first search query to the first content keyword. The query/CK whitelist table includes a number of entries, each entry mapping a search query to one or more content keywords. The query/CK whitelist table is utilized to identify content items in response to a subsequent search query.

Abstract: According to one embodiment, in response to a content description describing a content item, an analysis is performed on the content description. An image having image content is identified that is related to the content description based on the analysis. One or more phrases are derived from the content description based on the analysis, the one or more phrases summarizing the content description. A list of content styles is determined based on a relationship between the image and the one or more phrases. A composite content item having the image and the one or more phrases therein is generated based on a selected content style selected from the list of content styles. The image and the one or more phrases are arranged according to a layout corresponding to the selected content style.