Patents by Inventor Guangwu Chen

Guangwu Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ABIOTIC STRESS TOLERANT PLANTS AND METHODS
    Publication number: 20190177742
    Abstract: Isolated polynucleotides and polypeptides, and recombinant DNA constructs are useful for conferring improved drought tolerance, and/or for regulating flowering time. Compositions (such as plants or seeds) comprise these recombinant DNA constructs; and methods utilize these recombinant DNA constructs. The recombinant DNA constructs comprise a polynucleotide operably linked to a promoter that is functional in a plant, wherein said polynucleotides encode drought tolerance polypeptides and/or flowering time-regulating polypeptide.
    Type: Application
    Filed: June 29, 2017
    Publication date: June 13, 2019
    Applicants: PIONEER OVERSEAS CORPORATION, SINOBIOWAY BIO-AGRICULTURE GROUP CO., LTD.
    Inventors: GUANGWU CHEN, CHENGFENG DU, YANG GAO, SHANGWU LIANG, GUIHUA LU, GUANFAN MAO, XUGUANG TAN, CHANGGUI WANG, GUOKUI WANG
  • FLOWERING TIME-REGULATING GENES AND RELATED CONSTRUCTS AND APPLICATIONS THEREOF
    Publication number: 20190136247
    Abstract: Isolated polynucleotides and polypeptides, and recombinant DNA constructs useful for regulating plant heading date or flowering time are provided. Compositions (such as plants or seeds) comprising these recombinant DNA constructs, and methods utilizing these recombinant DNA constructs are also provided. The recombinant DNA constructs comprise a polynucleotide operably linked to a promoter that is functional in a plant, wherein said polynucleotides encode flowering time-regulating polypeptides.
    Type: Application
    Filed: March 30, 2017
    Publication date: May 9, 2019
    Applicants: PIONEER OVERSEAS CORPORATION, SINOBIOWAY BIO-AGRICULTURE GROUP CO., LTD.
    Inventors: GUANGWU CHEN, YANG GAO, SHANGWU LIANG, GUIHUA LU, GUANFAN MAO, CHAO SONG, XUGUANG TAN, CHANGGUI WANG
  • C—glycolipids with enhanced Th-1 profile
    Patent number: 8883745
    Abstract: The invention is directed to novel synthetic C-glycolipids that selectively induce a ThI-type immune response characterized by enhanced IL-12 secretion and increased activation of dendritic cells. The compounds of the invention are thereby useful in treating infections, cancers, cell proliferative disorders, and autoimmune diseases, both directly and as adjuvants.
    Type: Grant
    Filed: May 22, 2007
    Date of Patent: November 11, 2014
    Assignees: New York University, The Aaron Diamond Aids Research Center For The City Of New York, Research Foundation Of The City University Of New York
    Inventors: Moriya Tsuji, Guangwu Chen, Richard W. Franck, Guangli Yang
  • Synthetic C-glycolipid and its use for treating cancer, infectious diseases, and autoimmune diseases
    Patent number: 8252909
    Abstract: The invention is directed to compounds of formula (I) wherein X is O or NH; R? is a hydrocarbon chain; R3 and R4 are hydrogen, OH or a monosaccharide; R5 is hydrogen or a monosaccharide; Q? is optionally present and may be a C1-10 hydrocarbon; X? is optionally present and may be O, S or NR8; and Q3 may be a hydrocarbon or hydrogen. The invention is also directed to the use of the compounds for treating cancer, infectious diseases and autoimmune diseases. The invention is also directed to syntheses of the compounds of formula (I).
    Type: Grant
    Filed: July 29, 2005
    Date of Patent: August 28, 2012
    Assignees: New York University, The Research Foundation of the City University of New York
    Inventors: Moriya Tsuji, Guangwu Chen, Richard Franck, Guangli Yang
  • C-GLYCOLIPIDS WITH ENHANCED TH-1 PROFILE
    Publication number: 20100233207
    Abstract: The invention is directed to novel synthetic C-glycolipids that selectively induce a ThI-type immune response characterized by enhanced IL-12 secretion and increased activation of dendritic cells. The compounds of the invention are thereby useful in treating infections, cancers, cell proliferative disorders, and autoimmune diseases, both directly and as adjuvants.
    Type: Application
    Filed: May 22, 2007
    Publication date: September 16, 2010
    Applicants: New York University, Research Foundation of the City University of New York, The Aaron Diamond AIDS Research Center for the City of New York, Inc.
    Inventors: Moriya Tsuji, Guangwu Chen, Richard W. Franck, Guangli Yang
  • Synthetic C-glycolipid and its use for treating cancer, infectious diseases and autoimmune diseases
    Patent number: 7273852
    Abstract: The invention is directed to compounds of formula (I) wherein X is O or NH; R? is a hydrocarbon chain; R3 and R4 are hydrogen, OH or a monosaccharide; R5 is hydrogen or a monosaccharide; Q? is optionally present and may be a C1-10 hydrocarbon; X? is optionally present and may be O, S or NR8; and Q3 may be a hydrocarbon or hydrogen. The invention is also directed to the use of the compounds for treating cancer, infectious diseases and autoimmune diseases. The invention is also directed to syntheses of the compounds of formula (I).
    Type: Grant
    Filed: June 13, 2003
    Date of Patent: September 25, 2007
    Assignee: The Research Foundation of the City University of New York
    Inventors: Moriya Tsuji, Guangwu Chen, Richard Franck, Guangli Yang
  • Synthetic C-glycolipid and its use for treating cancer, infectious diseases, and autoimmune diseases
    Publication number: 20060019246
    Abstract: The invention is directed to compounds of formula (I) wherein X is O or NH; R? is a hydrocarbon chain; R3 and R4 are hydrogen, OH or a monosaccharide; R5 is hydrogen or a monosaccharide; Q? is optionally present and may be a C1-10 hydrocarbon; X? is optionally present and may be O, S or NR8; and Q3 may be a hydrocarbon or hydrogen. The invention is also directed to the use of the compounds for treating cancer, infectious diseases and autoimmune diseases. The invention is also directed to syntheses of the compounds of formula (I).
    Type: Application
    Filed: July 29, 2005
    Publication date: January 26, 2006
    Applicants: New York University, Research Foundation of the City University of New York
    Inventors: Moriya Tsuji, Guangwu Chen, Richard Franck, Guangli Yang
  • Novel synthetic C-glycolipids, their synthesis and use to treat infections, cancer and autoimmune diseases
    Publication number: 20050222048
    Abstract: The invention is directed to novel compounds of formulae (I), (II) and (III): wherein X is O or NH; R3 is OH or a monosaccharide and R4 is hydrogen, or R3 is hydrogen and R4 is OH or a monosaccharide; R5 is hydrogen or a monosaccharide; and pharmaceutically acceptable salts or esters thereof. The invention is also directed to the use of the compounds both directly and as immune adjuvants for treating cancer, infectious diseases and autoimmune diseases. The invention is also directed to syntheses of the intermediates which can be used to make these novel compounds.
    Type: Application
    Filed: March 31, 2005
    Publication date: October 6, 2005
    Applicants: The Research Foundation of The City University of New York, New York University
    Inventors: Moriya Tsuji, Richard Franck, Guangwu Chen