Patents by Inventor Gudrun Lange
Gudrun Lange has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8853496Abstract: The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from protists belonging to the family Blepharismidae, as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.Type: GrantFiled: December 23, 2010Date of Patent: October 7, 2014Assignee: Bayer CropScience AGInventors: Fabien Poree, Bernd Laber, Nathalie Knittel-Ottleben, Gudrun Lange, Arno Schulz, Ruediger Hain
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Patent number: 8847017Abstract: The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from bacteria belonging to the subfamily Synechococcoideae, as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.Type: GrantFiled: December 23, 2010Date of Patent: September 30, 2014Assignee: Bayer CropScience AGInventors: Fabien Poree, Bernd Laber, Nathalie Knittel-Ottleben, Gudrun Lange, Arno Schulz, Ruediger Hain
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Patent number: 8847018Abstract: The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from bacteria belonging to the genus Rhodococcus as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.Type: GrantFiled: December 23, 2010Date of Patent: September 30, 2014Assignee: Bayer CropScience AGInventors: Fabien Poree, Bernd Laber, Nathalie Knittel-Ottleben, Gudrun Lange, Arno Schulz, Ruediger Hain
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Publication number: 20140259213Abstract: The present invention relates to an isolated nucleic acid comprising a nucleotide sequence encoding a mutated HPPD protein, wherein said mutated HPPD protein has HPPD activity, wherein in said mutated HPPD protein at least one amino acid has been replaced so that the resulting amino acid sequence comprises at least one amino acid selected from certain amino acids at specific positions important for conferring an increased HPPD inhibitor tolerance. The present invention also relates to proteins encoded by the nucleic acid of the invention, to chimeric genes, plant cells comprising the nucleic acid of the invention operably linked to a plant-expressible promoter and optionally a transcription termination and polyadenylation region, plants essentially consisting of the plant cells of the invention and methods of obtaining transgenic plants.Type: ApplicationFiled: March 7, 2013Publication date: September 11, 2014Applicant: BAYER CROPSCIENCE AGInventors: Gudrun Lange, Fabien Poree, Bernd Laber, Joerg Freigang, Arno Schultz
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Patent number: 8688387Abstract: The present invention relates to the determination of intra- or intermolecular interaction between molecules in aqueous solution, the method comprising the steps of: (a) determining the dehydration of all atoms in the intermolecular interface, (b) adding the vacuum hydrogen bond energy, and (c) further adding the change in the free enthalpy of the interacting partners upon their interaction. The obtained results can be used for the prediction if and to what extent two molecules of various origin fit to each other.Type: GrantFiled: February 6, 2012Date of Patent: April 1, 2014Assignees: Bayer CropScience AG, Universitaet HamburgInventors: Gudrun Lange, Robert Klein, Juergen Albrecht, Matthias Rarey, Ingo Reulecke
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Patent number: 8457748Abstract: This invention relates to the use of vagus nerve stimulation for the treatment of fibromyalgia which comprises applying a therapeutic stimulation signal from a stimulus generator, when activated, to at least some of plural electrodes implanted in stimulating relation of the patient's vagus nerve and activating the stimulus generator to generate the therapeutic stimulation signal to alleviate the pain under treatment.Type: GrantFiled: February 6, 2009Date of Patent: June 4, 2013Assignee: University of Medicine and Dentistry of New JerseyInventor: Gudrun Lange
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Publication number: 20120202699Abstract: The present invention relates to the determination of intra- or intermolecular interaction between molecules in aqueous solution, the method comprising the steps of: (a) determining the dehydration of all atoms in the intermolecular interface, (b) adding the vacuum hydrogen bond energy, and (c) further adding the change in the free enthalpy of the interacting partners upon their interaction. The obtained results can be used for the prediction if and to what extent two molecules of various origin fit to each other.Type: ApplicationFiled: February 6, 2012Publication date: August 9, 2012Applicants: UNIVERSITAET HAMBURG, BAYER CROPSCIENCE AGInventors: Gudrun Lange, Robert Klein, Juergen Albrecht, Matthias Rarey, Ingo Reulecke
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Publication number: 20110263424Abstract: The present invention relates to novel oxaspirocyclic spirophenyl-substituted tetramic acid and tetronic acid derivatives of the formula (I) in which W, X, Y, Z, A, B, D, Q1, Q2, and G have the meanings given above, to a plurality of processes for their preparation and to their use as pesticides and/or herbicides. The invention also provides selective herbicidal compositions comprising, firstly, oxaspirocyclic spirophenyl-substituted tetramic acid and tetronic acid derivatives and, secondly, a crop plant compatibility-improving compound. The invention furthermore relates to increasing the activity of crop protection compositions comprising compounds of the formula (I) by addition of ammonium salts or phosphonium salts and, if appropriate, penetrants.Type: ApplicationFiled: July 22, 2008Publication date: October 27, 2011Applicant: Bayer CropScience AGInventors: Thomas Bretschneider, Reiner Fischer, Gudrun Lange, Stefan Lehr, Christian Arnold, Dieter Feucht, Eva-Maria Franken, Martin Jeffrey Hills, Heinz Kehne, Olga Malsam, Christopher Hugh Rosinger, Jan Dittgen, Ulrich Gorgens, Isolde Hauser-Hahn
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Publication number: 20110197309Abstract: The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from bacteria belonging to the subfamily Synechococcoideae, as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.Type: ApplicationFiled: December 23, 2010Publication date: August 11, 2011Applicant: Bayer CropScience AGInventors: Fabien Poree, Bernd Laber, Nathalie Knittel-Ottleben, Gudrun Lange, Arno Schulz, Ruediger Hain
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Publication number: 20110197308Abstract: The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from bacteria belonging to the genus Kordia, as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.Type: ApplicationFiled: December 23, 2010Publication date: August 11, 2011Applicant: Bayer CropScience AGInventors: Fabien Poree, Bernd Laber, Nathalie Knittel-Ottleben, Gudrun Lange, Arno Schulz, Ruediger Hain
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Publication number: 20110197310Abstract: The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from bacteria belonging to the genus Rhodococcus as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.Type: ApplicationFiled: December 23, 2010Publication date: August 11, 2011Applicant: Bayer CropScience AGInventors: Fabien Poree, Bernd Laber, Nathalie Knittel-Ottleben, Gudrun Lange, Arno Schulz, Ruediger Hain
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Publication number: 20110197307Abstract: The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from Euryarchaeota belonging to the family Picrophilaceae, as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.Type: ApplicationFiled: December 23, 2010Publication date: August 11, 2011Applicant: Bayer CropScience AGInventors: Fabien Poree, Bernd Laber, Nathalie Knittel-Ottleben, Gudrun Lange, Arno Schulz, Ruediger Hain
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Publication number: 20110191897Abstract: The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from protists belonging to the family Blepharismidae, as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.Type: ApplicationFiled: December 23, 2010Publication date: August 4, 2011Applicant: Bayer CropScience AGInventors: Fabien Poree, Bernd Laber, Nathalie Knittel-Ottleben, Gudrun Lange, Arno Schulz, Ruediger Hain
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Publication number: 20100273664Abstract: The present invention relates to the determination of intra- or intermolecular interaction between molecules in aqueous solution, said method comprising the steps of: (a) determining the dehydration (?Gdehydration) of all atoms in the intermolecular interface, (b) adding the vacuum hydrogen bond energy (?H-bond), and (c) further adding the change in the free enthalpy of the interacting partners upon their interaction. The obtained results can be used for the prediction if and to what extent two molecules of various origin fit to each other.Type: ApplicationFiled: October 20, 2007Publication date: October 28, 2010Applicants: BAYER CROPSCIENCE AG, UNIVERSITAET HAMBURGInventors: Gudrun Lange, Robert Klein, Juergen Albrecht, Matthias Rarey, Ingo Reulecke
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Publication number: 20090264959Abstract: This invention relates to the use of vagus nerve stimulation for the treatment of fibromyalgia which comprises applying a therapeutic stimulation signal from a stimulus generator, when activated, to at least some of plural electrodes implanted in stimulating relation of the patient's vagus nerve and activating the stimulus generator to generate the therapeutic stimulation signal to alleviate the pain under treatment.Type: ApplicationFiled: February 6, 2009Publication date: October 22, 2009Inventor: Gudrun Lange