Patents by Inventor Gunter Fuhr
Gunter Fuhr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240027977Abstract: The invention relates to a method implemented in a control system of a machine for processing input values in an overall system with a working level and an evaluation level comprising inputting first input values to the working level and determining first output values; forming first situation data; inputting the first situation data to the evaluation level and determining first evaluations indicating whether the first situation data satisfy predetermined first conditions; influencing the determination of the first output values based on the first evaluations; inputting second input values to the working level and determining second output values, wherein the determination of the second output values is influenced by the first output values; forming second situation data; inputting the second situation data to the evaluation level and determining second evaluations indicating whether the second situation data satisfy predetermined second conditions, the determining of the second evaluations being influenceType: ApplicationFiled: November 19, 2021Publication date: January 25, 2024Inventors: Heiko ZIMMERMANN, GüNTER FUHR, Antonie FUHR
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Publication number: 20220292331Abstract: Provided are methods in a system of at least a second and a third artificial intelligence unit, comprising: inputting first input values to at least one second artificial intelligence unit, and obtaining output values based on the input values from the at least one second artificial intelligence unit; at least temporarily storing situation data, the situation data comprising first input values and/or second output values of the at least one second unit; using the situation data as input values of the third artificial intelligence unit, the third artificial intelligence unit generating third output values in response to the input values; and checking whether the second output values of the at least one second unit satisfy one or more predetermined conditions based on the third output values. Also provided is a system for carrying out such a method.Type: ApplicationFiled: March 9, 2020Publication date: September 15, 2022Applicants: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V., UNIVERSITÄT DES SAARLANDESInventors: Heiko ZIMMERMANN, Günter FUHR, Antonie FUHR
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Publication number: 20220245429Abstract: Provided is a method in a system of at least two artificial intelligence units, comprising inputting input values to at least a first artificial intelligence unit and a second artificial intelligence unit; obtaining first output values of the first artificial intelligence unit; forming one or more modulation functions based on the output values of the first artificial intelligence unit; applying the formed one or more modulation functions to one or more parameters of the second artificial intelligence unit, the one or more parameters influencing the processing of input values and the obtaining of output values in the second artificial intelligence unit; and finally obtaining second output values of the second artificial intelligence unit.Type: ApplicationFiled: March 9, 2020Publication date: August 4, 2022Applicants: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V., UNIVERSITÄT DES SAARLANDESInventors: Heiko ZIMMERMANN, Günter FUHR, Antonie FUHR
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Patent number: 9375514Abstract: The invention relates to methods for producing three-dimensional multicellular tissue and organ culture systems using multicellular mammalian cell aggregates, these systems themselves and their use for various medical purposes, in particular implantations.Type: GrantFiled: May 9, 2005Date of Patent: June 28, 2016Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V.Inventors: Charli Kruse, Gunter Fuhr
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Patent number: 8584473Abstract: The invention relates to a cooling apparatus, especially for cryogenically preserving biological samples, comprising a duct (5) for delivering a coolant (3) to a cooling chamber (1), a heater (6) that has an adjustable first heating performance (P2) for heating the coolant (3) delivered to the cooling chamber (1), a first temperature sensor (8-10) for measuring the temperature (T2-T4) in the cooling chamber (1), a second temperature sensor (7) for measuring the temperature (T1) of the coolant (3) delivered to the cooling chamber (1), and a regulator (11) for regulating the temperature. Said regulator (11) is embodied as a multiple regulator which detects several temperatures (T1-T4) as control variables and/or adjusts several heating performances (P1, P2) as manipulated variables. The invention further relates to a corresponding operating method.Type: GrantFiled: October 6, 2004Date of Patent: November 19, 2013Assignee: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung, e.V.Inventors: Uwe Schon, Heiko Zimmermann, Gunter Fuhr
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Patent number: 8298822Abstract: Disclosed is a method for forming epithelial cells. Said method comprises the steps of aggregating stem cells from differentiated exocrine gland tissue to obtain an organoid body and differentiating at least one portion of the organoid body or a tissue body grown therefrom to obtain epithelial cells. Also disclosed is a cultivation device, particularly for forming differential epithelial cells.Type: GrantFiled: April 1, 2005Date of Patent: October 30, 2012Assignee: Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung E.V.Inventors: Charli Kruse, Gunter Fuhr, Thilo Wedel
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Patent number: 8283132Abstract: The invention relates to a method for treating a biological cell (1) including a cytoskeleton (3) enveloped by a cell membrane (2). The method includes the following steps: the biological cell (1) and a tool (10) are mutually oriented such that the tool (10) comes into contact with the biological cell (1); the tool (10) and the biological cell (1) are displaced in relation to each other; and a gap is formed in the molecular composite of the cell membrane (2) of the biological cell (1). During the displacement of the tool (10), the cytoskeleton (3) of the biological cell (1) has a state of equilibrium. The invention also relates to a cell manipulator for carrying out the inventive method.Type: GrantFiled: November 2, 2005Date of Patent: October 9, 2012Assignee: Fraunhofer-Gesellschaft zur Foerderung der Angewandten Forshung e.V.Inventors: Günter Fuhr, Hagen Thielecke
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Patent number: 8241906Abstract: The invention relates to a cell carrier (10) for receiving a biological sample. The carrier comprises a magnetic element (20) and a floor element (30) that forms a stable support (31) that can be displaced on a solid base surface in at least one direction. The invention also relates to a manipulation device for biological samples and to a method for manipulating biological samples.Type: GrantFiled: February 25, 2005Date of Patent: August 14, 2012Assignee: Fraunhofer-Gesellschaft zur Forderung der Angewandten Forschung E.V.Inventor: Gunter Fuhr
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Patent number: 7984616Abstract: A cryostorage device (100) is described that includes at least one data storage device (200) and at least one sample receptacle device (300) with at least one sample chamber (301, 302, etc.) for the uptake of a suspension sample, the at least one sample chamber (301, 302, etc.) being connected to the data storage device (200) and having a elongated, hollow shape that extends from an inlet end (320) over a predetermined length to an outlet end (330) and being attached to the at least one data storage device (200) in a flexible and movably hanging manner.Type: GrantFiled: April 20, 2005Date of Patent: July 26, 2011Assignee: Fraunhofer-Gesellschaft zur Forderung der Angewandten Forschung E.V.Inventors: Günter Fuhr, Heiko Zimmermann
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Patent number: 7634917Abstract: The invention relates to a cryoapparatus for freezing and/or thawing a sample (1), especially in the cryopreservation of a biological sample (1), with a coolable cooling space (3) and with a sample container (10) arranged in the cooling space (3) for temporarily receiving the sample (1) when freezing or thawing the sample (1). It is suggested that the sample container (10) can be tempered separately from the cooling space. Furthermore, the invention includes an associated operating method.Type: GrantFiled: September 30, 2005Date of Patent: December 22, 2009Assignee: Fraunhofer-Gesellschaft zur Forderung der Angewandten Forschung E.V.Inventors: Günter Fuhr, Heiko Zimmermann, Young-Joo Oh, Uwe Schön
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Patent number: 7596957Abstract: The invention relates to a device and method for handling a probe, in particular, for treating, examining, inserting or extracting a cryoprobe. According to the invention, said probe is surrounded by an ambient gas, during handling, and an air-conditioning device (33) cools, dries and/or at least partially replaces the ambient gas by a protective gas, in order to prevent deterioration of the probe by the ambient gas during handling.Type: GrantFiled: July 19, 2004Date of Patent: October 6, 2009Assignee: Fraunhofer-Gesellschaft zur Forderung der Angewandten Forschung e.V.Inventors: Günter Fuhr, Uwe Schön, Heiko Zimmermann, Young-Joo Oh
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Publication number: 20090226994Abstract: The present invention relates to a method and device for non-intrusively manipulating suspended particles and/or cells and/or viruses, which are supplied to a micro-chamber or to a micro-channel (46) of a substrate, said micro-chamber or micro-channel (46) having at least a bottom wall as well as lateral walls. At least one acoustic wave (41) is applied via at least one acoustic transducer (42, 44) from outside of said substrate to an inner volume of said micro-chamber or micro-channel (46), a frequency of said acoustic wave (41) being selected to generate a standing and/or stationary acoustic wave in said volume. In the present method and device the acoustic wave (41) is applied laterally to said volume. The present device and method allow an efficient coupling of energy into the channels as well as an improved control of standing and/or stationary acoustic wave fields along the channels.Type: ApplicationFiled: July 7, 2005Publication date: September 10, 2009Applicant: FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V.Inventors: Robert Lemor, Christian Günther, Günter Fuhr, Martin Wiklund, Hans Hertz
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Publication number: 20090148880Abstract: The invention relates to a method for treating a biological cell (1) including a cytoskeleton (3) enveloped by a cell membrane (2). The method includes the following steps: the biological cell (1) and a tool (10) are mutually oriented such that the tool (10) comes into contact with the biological cell (1); the tool (10) and the biological cell (1) are displaced in relation to each other; and a gap is formed in the molecular composite of the cell membrane (2) of the biological cell (1). During the displacement of the tool (10), the cytoskeleton (3) of the biological cell (1) has a state of equilibrium. The invention also relates to a cell manipulator for carrying out the inventive method.Type: ApplicationFiled: November 2, 2005Publication date: June 11, 2009Applicant: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.Inventors: Günter Fuhr, Hagen Thielecke
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Patent number: 7458285Abstract: The invention relates to a sample receiving device (100), particularly for the cryoconservation of at least one sample, including a bundle (10) consisting of a plurality of hose-shaped flexible sample chambers (11, 12, . . . ) and a holding device (20) with which the bundle (10) of the sample chambers is joined. The holding device (20) has a plurality of holding frames (21, 22, . . . ) which are arranged in a longitudinal direction of the bundle (10).Type: GrantFiled: June 23, 2004Date of Patent: December 2, 2008Assignee: Fraunhofer-Gesellschaft zur Foerderung der Angewandten Forschung e.V.Inventors: Günter Fuhr, Heiko Zimmermann, Thomas Fixemer
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Patent number: 7439075Abstract: A method of discharging a fluid flow with suspended microparticles from a fluidic microsystem (10) is described, whereby the fluid flow converges with at least one output flow to form a discharge flow at the end of a discharge channel (14) of the microsystem, and the discharge flow is delivered through a conduction element (19). A microsystem with a flow output device for implementation of this method is also described.Type: GrantFiled: February 8, 2001Date of Patent: October 21, 2008Assignee: Perkinelmer Cellular Technologies Germany GmbHInventors: Gunter Fuhr, Stephen Graham Shirley, Torsten Muller, Thomas Schnelle, Rolf Hagedorn
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Publication number: 20080193420Abstract: Disclosed is a method for forming epithelial cells. Said method comprises the steps of aggregating stem cells from differentiated exocrine gland tissue to obtain an organoid body and differentiating at least one portion of the organoid body or a tissue body grown therefrom to obtain epithelial cells. Also disclosed is a cultivation device, particularly for forming differential epithelial cells.Type: ApplicationFiled: April 1, 2005Publication date: August 14, 2008Inventors: Charli Kruse, Gunter Fuhr, Thilo Wedel
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Publication number: 20080193421Abstract: The invention relates to methods for producing three-dimensional multicellular tissue and organ culture systems using multicellular mammalian cell aggregates, these systems themselves and their use for various medical purposes, in particular implantations.Type: ApplicationFiled: May 9, 2005Publication date: August 14, 2008Applicant: FRAUNHOFER GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDInventors: Charli Kruse, Gunter Fuhr
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Publication number: 20080113400Abstract: Methods are described for the cultivation of stem cells (2, 3, 5), comprising the steps: Introduction of cell material comprising at least one stem cell (2, 3, 5) of a donor organism into a host egg (4) with a nutrient reservoir, and cultivation of the cell material in the host egg (4), a cell culture, and a cell culture device for carrying out the method.Type: ApplicationFiled: May 9, 2005Publication date: May 15, 2008Inventors: Charli Kruse, Gunter Fuhr
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Publication number: 20080064034Abstract: The invention relates to methods for testing substances using multicellular in vitro test systems, in particular systems that resemble organs, and to devices and kits for carrying out said methods.Type: ApplicationFiled: March 2, 2005Publication date: March 13, 2008Applicant: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDInventors: Charli Kruse, Günter Fuhr
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Publication number: 20080038806Abstract: The invention relates to a cell carrier (10) for receiving a biological sample. Said carrier comprises a magnetic element (20) and a floor element (30) that forms a stable support (31) that can be displaced on a solid base surface in at least one direction. The invention also relates to a manipulation device for biological samples and to a method for manipulating biological samples.Type: ApplicationFiled: February 25, 2005Publication date: February 14, 2008Inventor: Gunter Fuhr