Patents by Inventor Guoan Zheng

Guoan Zheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160088205
    Abstract: Certain embodiments pertain to Multiplexed Fourier Ptychographic imaging systems and methods. In one example, the Multiplexed Fourier Ptychographic imaging system includes an LED array configured to illuminate a sequence of LED patterns for illuminating a sample being imaged. The system includes LED circuitry configured to independently control power to turn on multiple LEDs simultaneously in each LED pattern of the array. The system has a light detector that acquires a first set of lower resolution images of the sample each image acquired during exposure time during illumination by a unique LED pattern. The system uses the first set of lower resolution images to generate a second set of lower resolution images associated with each LED in the LED array and iteratively updates overlapping regions in the Fourier domain with the second set of lower resolution images to generate a higher resolution image.
    Type: Application
    Filed: December 4, 2015
    Publication date: March 24, 2016
    Inventors: Roarke W. Horstmeyer, Guoan Zheng, Changhuei Yang
  • Publication number: 20150317508
    Abstract: In one aspect, the present disclosure provides a system for Fourier ptychographic microscopy, the system comprising (i) an image capture apparatus including an objective lens, (ii) at least one processor, and (iii) data storage including program instructions stored thereon that when executed by the at least one processor, cause the system to: (a) capture, via the image capture apparatus, a plurality of initial images of an object, wherein each of the plurality of initial images of the object have a first resolution, and (b) process each of the plurality of initial images in Fourier space to generate a final image of the object having a second resolution, wherein the second resolution is greater than the first resolution.
    Type: Application
    Filed: April 30, 2015
    Publication date: November 5, 2015
    Inventors: Guoan Zheng, Siyuan Dong
  • Publication number: 20150160450
    Abstract: Certain aspects pertain to Fourier ptychographic imaging systems, devices, and methods that implement an embedded pupil function recovery
    Type: Application
    Filed: December 16, 2014
    Publication date: June 11, 2015
    Inventors: Xiaoze Ou, Jaebum Chung, Roarke Horstmeyer, Guoan Zheng, Changhuei Yang
  • Patent number: 9041938
    Abstract: A surface wave assisted system having an aperture layer with a surface and an aperture, and a plurality of grooves around the aperture. The plurality of grooves is configured to generate an optical transfer function at the aperture by inducing a surface wave for interfering with transmission of light of a range of spatial frequency.
    Type: Grant
    Filed: January 5, 2012
    Date of Patent: May 26, 2015
    Assignee: California Institute of Technology
    Inventors: Guoan Zheng, Xiquan Cui, Xin Heng, Changhuei Yang, Axel Scherer
  • Publication number: 20150054979
    Abstract: Certain aspects pertain to Fourier ptychographic imaging systems, devices, and methods such as, for example, high NA Fourier ptychographic imaging systems and reflective-mode NA Fourier ptychographic imaging systems.
    Type: Application
    Filed: August 22, 2014
    Publication date: February 26, 2015
    Inventors: Xiaoze Ou, Roarke Horstmeyer, Guoan Zheng, Changhuei Yang
  • Publication number: 20150036038
    Abstract: Certain aspects pertain to aperture-scanning Fourier ptychographic imaging devices comprising an aperture scanner that can generate an aperture at different locations at an intermediate plane of an optical arrangement, and a detector that can acquire lower resolution intensity images for different aperture locations, and wherein a higher resolution complex image may be constructed by iteratively updating regions in Fourier space with the acquired lower resolution images.
    Type: Application
    Filed: July 31, 2014
    Publication date: February 5, 2015
    Inventors: Roarke Horstmeyer, Guoan Zheng, Xiaoze Ou, Changhuei Yang
  • Patent number: 8946619
    Abstract: A Talbot-illuminated imaging system for focal plane tuning, the device comprising a Talbot element, a tunable illumination source, a scanning mechanism, a light detector, and a processor. The element generate san array of focused light spots at a focal plane. The tunable illumination source shifts the focal plane to a plane of interest by adjusting a wavelength of light incident the Talbot element. The scanning mechanism scans an object across an array of focused light spots in a scanning direction. The light detector determines time-varying light data associated with the array of focused light spots as the object scans across the array of light spots. The processor constructs an image of the object based on the time-varying data.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: February 3, 2015
    Assignee: California Institute of Technology
    Inventors: Jigang Wu, Shuo Pang, Zheng Li, Guoan Zheng, Changhuei Yang
  • Patent number: 8822894
    Abstract: A light-field pixel for detecting a wavefront, the light-field pixel comprises an aperture layer, a light detector layer, and a processor. The aperture layer has a non-conventional aperture and a non-conventional aperture. The non-conventional aperture has a higher gradient of transmission at normal incidence than the conventional aperture. The light detector is configured to measure a first intensity of light through the non-conventional aperture and a second intensity of light through the conventional aperture. The processor is configured to detect the wavefront based on the first intensity normalized by the second intensity.
    Type: Grant
    Filed: January 5, 2012
    Date of Patent: September 2, 2014
    Assignee: California Institute of Technology
    Inventors: Guoan Zheng, Changhuei Yang
  • Publication number: 20140133702
    Abstract: Methods of rapid distinction between growing cells and debris, which determine a time-lapse movie of specimen images, track features of each entity, and categorize each entity as growing cells or debris.
    Type: Application
    Filed: November 5, 2013
    Publication date: May 15, 2014
    Applicant: California Institute of Technology
    Inventors: Guoan Zheng, Samuel Yang, Seung Ah Lee, Shuo Pang, Changhuei Yang, Benjamin Judkewitz, Ying Min Wang
  • Publication number: 20140126691
    Abstract: Methods, systems, and devices of Fourier ptychographic X-ray imaging by capturing a plurality of variably-illuminated, low-resolution intensity X-ray images of a specimen and computationally reconstructing a high-resolution X-ray image of the specimen by iteratively updating overlapping regions in Fourier space with the variably-illuminated, low-resolution intensity X-ray images.
    Type: Application
    Filed: October 28, 2013
    Publication date: May 8, 2014
    Applicant: California Institute of Technology
    Inventors: Guoan Zheng, Changhuei Yang, Roarke Horstmeyer
  • Publication number: 20140118529
    Abstract: Systems, devices, and methods of Fourier ptychographic imaging by computationally reconstructing a high-resolution image by iteratively updating overlapping regions of variably-illuminated, low-resolution intensity images in Fourier space.
    Type: Application
    Filed: October 28, 2013
    Publication date: May 1, 2014
    Applicant: California Institute of Technology
    Inventors: Guoan Zheng, Changhuei Yang, Roarke Horstmeyer
  • Publication number: 20120267515
    Abstract: A Talbot-illuminated imaging system for focal plane tuning, the device comprising a Talbot element, a tunable illumination source, a scanning mechanism, a light detector, and a processor. The element generate san array of focused light spots at a focal plane. The tunable illumination source shifts the focal plane to a plane of interest by adjusting a wavelength of light incident the Talbot element. The scanning mechanism scans an object across an array of focused light spots in a scanning direction. The light detector determines time-varying light data associated with the array of focused light spots as the object scans across the array of light spots. The processor constructs an image of the object based on the time-varying data.
    Type: Application
    Filed: April 20, 2012
    Publication date: October 25, 2012
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Jigang Wu, Shuo Pang, Zheng Li, Guoan Zheng, Changhuei Yang
  • Publication number: 20120250027
    Abstract: A surface wave assisted system having an aperture layer with a surface and an aperture, and a plurality of grooves around the aperture. The plurality of grooves is configured to generate an optical transfer function at the aperture by inducing a surface wave for interfering with transmission of light of a range of spatial frequency.
    Type: Application
    Filed: January 5, 2012
    Publication date: October 4, 2012
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Guoan Zheng, Xiquan Cui, Xin Heng, Changhuei Yang, Axel Scherer
  • Publication number: 20120223217
    Abstract: An e-Petri dish comprising a transparent layer having a specimen surface and a light detector configured to sample a sequence of sub-pixel shifted projection images of a specimen located on the specimen surface. The sub-pixel shifted projection images associated with light from a plurality of illumination angles provided by an illumination source.
    Type: Application
    Filed: March 2, 2012
    Publication date: September 6, 2012
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Guoan Zheng, Samuel Yang, Seung Ah Lee, Shuo Pang, Changhuei Yang
  • Publication number: 20120223214
    Abstract: A light guided pixel having a guide layer and a light detector layer. The guide layer has a light guide. The light detector layer has a light detecting element that receives light channeled by the light guide. The light guide may include a filter for channeling emissions to the light detecting element.
    Type: Application
    Filed: March 2, 2012
    Publication date: September 6, 2012
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Seung Ah Lee, Guoan Zheng, Benjamin Judkewitz, Shuo Pang, Jigang Wu, Changhuei Yang
  • Publication number: 20120211644
    Abstract: A light-field pixel for detecting a wavefront, the light-field pixel comprises an aperture layer, a light detector layer, and a processor. The aperture layer has a non-conventional aperture and a non-conventional aperture. The non-conventional aperture has a higher gradient of transmission at normal incidence than the conventional aperture. The light detector is configured to measure a first intensity of light through the non-conventional aperture and a second intensity of light through the conventional aperture. The processor is configured to detect the wavefront based on the first intensity normalized by the second intensity.
    Type: Application
    Filed: January 5, 2012
    Publication date: August 23, 2012
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Guoan Zheng, Changhuei Yang
  • Patent number: 8189204
    Abstract: Embodiments of the present invention relate to a surface wave enabled darkfield aperture structure comprising an aperture layer, a aperture in the aperture layer and a plurality of grooves around the aperture. The aperture layer has a first and second surface. The plurality of grooves is in the first surface. A surface wave propagates along at least the first surface. The plurality of grooves is configured to generate a darkfield at the aperture by modifying the surface wave to cancel out direct transmission of a uniform incident light field received by the aperture.
    Type: Grant
    Filed: June 2, 2010
    Date of Patent: May 29, 2012
    Assignee: California Institute of Technology
    Inventors: Xiquan Cui, Xin Heng, Changhuei Yang, Axel Scherer, Demetri Psaltis, Guoan Zheng
  • Publication number: 20120098950
    Abstract: A scanning projective lensless microscope device comprises a specimen surface, a scanning illumination source with a light element, a light detector outside the specimen surface, and a processor. The scanning illumination source scans the light element to a plurality of scanning locations to provide illumination to an object on the specimen surface. The light detector samples a sequence of sub-pixel shifted projection object images corresponding to the plurality of scanning locations. The processor constructs a high resolution image of the object based on the sequence of sub-pixel shifted projection images and a motion vector of the projections at a plane of interest.
    Type: Application
    Filed: October 25, 2011
    Publication date: April 26, 2012
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Guoan Zheng, Samuel Yang, Seung Ah Lee, Changhuei Yang
  • Publication number: 20110234757
    Abstract: A super resolution optofluidic microscope device comprises a body defining a fluid channel having a longitudinal axis and includes a surface layer proximal the fluid channel. The surface layer has a two-dimensional light detector array configured to receive light passing through the fluid channel and sample a sequence of subpixel shifted projection frames as an object moves through the fluid channel. The super resolution optofluidic microscope device further comprises a processor in electronic communication with the two-dimensional light detector array. The processor is configured to generate a high resolution image of the object using a super resolution algorithm, and based on the sequence of subpixel shifted projection frames and a motion vector of the object.
    Type: Application
    Filed: March 23, 2011
    Publication date: September 29, 2011
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Guoan Zheng, Changhuei Yang, Samuel Yang, Seung Ah Lee
  • Publication number: 20110075254
    Abstract: Embodiments of the present invention relate to a surface wave enabled darkfield aperture structure comprising an aperture layer, a aperture in the aperture layer and a plurality of grooves around the aperture. The aperture layer has a first and second surface. The plurality of grooves is in the first surface. A surface wave propagates along at least the first surface. The plurality of grooves is configured to generate a darkfield at the aperture by modifying the surface wave to cancel out direct transmission of a uniform incident light field received by the aperture.
    Type: Application
    Filed: June 2, 2010
    Publication date: March 31, 2011
    Inventors: Xiquan Cui, Xin Heng, Changhuei Yang, Axel Scherer, Demetri Psaltis, Guoan Zheng