Patents by Inventor Guohua Chen

Guohua Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220011563
    Abstract: The invention claims a microscopic imaging method of phase contrast (PC) and differential interference contrast (DIC) based on the transport of intensity equation (TIE). Firstly, three intensity images are captured along the optical axis; secondly, TIE is solved by deconvolution to obtain the quantitative phase; then, the intensity image under the DIC imaging mode is obtained according to the DIC imaging principle; finally, the corresponding phase image of PC imaging mode is obtained according to the PC imaging principle. The proposed approach can endow the bright-field microscope with the ability to realize PC and DIC imaging without complex modification of the traditional bright-field microscope. In other words, this method only needs to use the traditional bright-field microscope without adding any complex hardware. Through the PC and DIC algorithms, this method has the advantages of quantitative, high-speed, low-cost, simple structure, and less external interference.
    Type: Application
    Filed: July 5, 2019
    Publication date: January 13, 2022
    Applicant: NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chao ZUO, Qian CHEN, Jiasong SUN, Yuzhen ZHANG, Guohua GU
  • Patent number: 11179326
    Abstract: Methods and compositions for systemically or locally administering by implantation a beneficial agent to a subject are described, and include, for example, depot gel compositions that can be injected into a desired location and which can provide controlled release of a beneficial agent over a short duration of time. The compositions include a low molecular weight biocompatible polymer, a biocompatible solvent having low water miscibility that forms a viscous gel with the polymer and limits water uptake by the implant, and a beneficial agent.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: November 23, 2021
    Assignee: Durect Corporation
    Inventors: Guohua Chen, David T. Priebe
  • Publication number: 20210316993
    Abstract: A method for preparing functionalized graphene. (1) Flake graphite and a dienophile or a diene are mixed in an organic solvent uniformly to obtain a mixed solution. (2) In an inert atmosphere or under vacuum, the mixed solution obtained in step (1) is subjected to graphite exfoliation and Diels-Alder (DA) reaction in a mechanical exfoliation device to obtain a crude product. (3) The crude product obtained in step (2) is subjected to heat preservation to obtain the functionalized graphene.
    Type: Application
    Filed: June 25, 2021
    Publication date: October 14, 2021
    Inventors: Guohua CHEN, Jianfeng XU, Songlin CHEN
  • Publication number: 20210317327
    Abstract: Graphene-based conductive ink and a preparation thereof. The graphene-based conductive ink includes a modified graphene nanomaterial, a first solvent and an ink binder. The modified graphene nanomaterial is prepared by subjecting a mixture of sodium sulfanilate, a natural flake graphite and a second solvent to liquid phase exfoliation. The second solvent is a mixture of water and a second alcohol.
    Type: Application
    Filed: June 25, 2021
    Publication date: October 14, 2021
    Inventors: Guohua CHEN, Xinbin QIU, Feixiang LIU
  • Publication number: 20210311744
    Abstract: A microprocessor with a multistep-ahead branch predictor is shown. The branch predictor is coupled to an instruction cache and has an N-stage pipelined architecture, which is configured to perform branch prediction to control the instruction fetching of the instruction cache. The branch predictor performs branch prediction for (N-1) instruction-address blocks in parallel, wherein the (N-1) instruction-address blocks include a starting instruction-address block and (N-2) subsequent instruction-address blocks. The branch predictor is thereby ahead of branch prediction of the starting instruction-address block. The branch predictor stores reference information about branch prediction in at least one memory and performs a parallel search of the memory for the branch prediction of the (N-1) instruction-address blocks.
    Type: Application
    Filed: October 29, 2020
    Publication date: October 7, 2021
    Inventors: Fangong GONG, Mengchen YANG, Guohua CHEN
  • Publication number: 20210300762
    Abstract: A self-stabilized dispersed graphene nano-material and a preparation method thereof. The self-stabilized dispersed graphene nano-material is prepared by a liquid phase exfoliation with sodium p-aminobenzenesulfonate, a natural flake graphite and an alcohol-water mixed solvent, wherein sodium p-aminobenzenesulfonate is present on the surface of graphene by ?-? conjugation, physical adsorption and chemical grafting. The self-stabilized dispersed graphene nano-material has good water dispersion capacity, and excellent electrical conductivity, is easy for industrial production, and has enormous potential in graphene application.
    Type: Application
    Filed: July 23, 2020
    Publication date: September 30, 2021
    Inventors: Guohua Chen, Xinbin Qiu, Feixiang Liu
  • Patent number: 11110093
    Abstract: An injectable depot formulation includes a biocompatible polymer, an organic solvent combined with the biocompatible polymer to form a viscous gel, and a small molecule drug incorporated in the viscous gel such that the formulation exhibits an in vivo release profile having a Cmax to Cmin ratio of less than 200 and a lag time less than 0.2.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: September 7, 2021
    Assignee: INDIVIOR UK LIMITED
    Inventors: Andrew S. Luk, Gunjan H. Junnarkar, Guohua Chen
  • Publication number: 20210206644
    Abstract: The present disclosure discloses a substituted graphane material with a three-dimensional structure. The substituted graphane material comprises a planar substrate with a plurality of six-membered carbon rings comprising continuous sp3 hybrids, wherein an organic molecular ring is connected to the planar substrate due to a Diels-Alder (D-A) reaction.
    Type: Application
    Filed: March 4, 2021
    Publication date: July 8, 2021
    Inventors: Guohua CHEN, Songlin CHEN, Xiaomin ZHAO, Danqing CHEN, Lengshen HUANG, Yajing HUANG
  • Patent number: 11052231
    Abstract: Devices and methods for using and manufacturing microstructure arrays having at least a detachable distal area are described.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: July 6, 2021
    Assignee: Corium, Inc.
    Inventors: Zhongli Ding, Guohua Chen, Ashutosh Shastry, Robert Wade Worsham, Parminder Singh
  • Publication number: 20210044033
    Abstract: A bolt terminal mounted on a guide rail is provided. The bolt terminal comprises a housing (1), an integral nut (2), a screw (3), a connection component (4), and a wiring metal surface (5); one end of the screw is provided in the housing, the other end of the screw is located outside the housing, and the screw located outside the housing is to be connected to the integral nut fitted therewith; the wiring metal surface is provided on the interface between the screw and the housing; and the housing is to be connected to the guide rail via the connection component. The bolt terminal increases the requirement for powering the wirings, and the bolt terminal can be removed from the guide rail only by using a conventional screwdriver to lightly tap on a removal port. The screw is integrally connected to the housing by injection molding and thus there is no risk of the screw falling off, enabling higher reliability.
    Type: Application
    Filed: March 22, 2019
    Publication date: February 11, 2021
    Inventors: Tianhua Zhang, Guohua Chen, Michael Reineke
  • Publication number: 20200405630
    Abstract: A method and a drug delivery system for transdermally administering parathyroid hormone (PTH) in a pulsatile fashion are provided, where the drug delivery system comprises an array of microprojections each comprising PTH.
    Type: Application
    Filed: February 10, 2020
    Publication date: December 31, 2020
    Inventors: Parminder Singh, Danir Bayramov, Guohua Chen, Robert Wade Worsham
  • Publication number: 20200296903
    Abstract: A soil bed covering and planting apparatus is adapted to be carried along the length of a soil bed by a conveyer vehicle and includes a cover material reel configured to retain and supply a sheet of cover material, and a compaction roller configured to feed cover material over a soil bed and to press the cover material onto the soil bed. Two spike hammers are positioned adjacent to and at opposite sides of the compaction roller, each being configured to drive at least one spike through the cover material into the soil bed. An actuation structure is associated with each spike hammer and urges the spike hammer against a spike. A piercing assembly forms a series of holes in the sheet of cover material and engages with a drive structure that reciprocates the piercing assembly to drive one end of the piercing assembly through the sheet of cover material.
    Type: Application
    Filed: March 18, 2020
    Publication date: September 24, 2020
    Applicant: CGECHEN LIMITED
    Inventor: Guohua CHEN
  • Publication number: 20200237654
    Abstract: A microprojection array comprising an approximately planar base and a plurality of microprojections, wherein the array comprises a therapeutic agent that is poorly soluble in water or an aqueous solvent.
    Type: Application
    Filed: April 17, 2020
    Publication date: July 30, 2020
    Inventors: Zhongli DING, Guohua CHEN, Parminder SINGH
  • Publication number: 20200129425
    Abstract: Methods and compositions for systemically or locally administering by implantation a beneficial agent to a subject are described, and include, for example, depot gel compositions that can be injected into a desired location and which can provide controlled release of a beneficial agent over a short duration of time. The compositions include a low molecular weight biocompatible polymer, a biocompatible solvent having low water miscibility that forms a viscous gel with the polymer and limits water uptake by the implant, and a beneficial agent.
    Type: Application
    Filed: September 26, 2019
    Publication date: April 30, 2020
    Inventors: Guohua Chen, David T. Priebe
  • Patent number: D902630
    Type: Grant
    Filed: March 24, 2020
    Date of Patent: November 24, 2020
    Assignee: SHAOXING HUAQIN HOME TEXTILE CO., LTD.
    Inventor: Guohua Chen
  • Patent number: D903379
    Type: Grant
    Filed: August 21, 2020
    Date of Patent: December 1, 2020
    Assignee: SHAOXING HUAQIN HOME TEXTILE CO., LTD.
    Inventor: Guohua Chen
  • Patent number: D909094
    Type: Grant
    Filed: April 3, 2020
    Date of Patent: February 2, 2021
    Assignee: SHAOXING HUAQIN HOME TEXTILE CO., LTD.
    Inventor: Guohua Chen
  • Patent number: D914652
    Type: Grant
    Filed: December 15, 2020
    Date of Patent: March 30, 2021
    Assignee: SHENZHEN SIXPIPES TECHNOLOGY CO., LTD
    Inventor: Guohua Chen
  • Patent number: D920293
    Type: Grant
    Filed: November 26, 2020
    Date of Patent: May 25, 2021
    Assignee: SHENZHEN SIXPIPES TECHNOLOGY CO., LTD
    Inventor: Guohua Chen
  • Patent number: D925500
    Type: Grant
    Filed: January 13, 2021
    Date of Patent: July 20, 2021
    Assignee: SHENZHEN SIXPIPES TECHNOLOGY CO., LTD
    Inventor: Guohua Chen