Abstract: A sensor for determining the presence of an analyte in a test sample, said sensor comprising a nanoparticulate membrane comprising nanoparticles of at least one inorganic oxide of an element selected from Group IA, IIA, IIIA, IVA, IB, IIB, IIIB, IVAB, VB, VIB, VIII3 or VIIII3 of the Periodic Table, and wherein an oxidoreductase and an electrochemical activator are diffusibly dispersed in said nanoparticulate membrane.

Abstract: A device for sample tissue disruption and/or cell lysis comprising: a piezoelectric material; and at least a second material in contact with the piezoelectric material; and wherein the second material has an uneven surface on an opposite side to that in contact with the piezoelectric material. The device may be made by assembling at least three layers and membranes for the valves and pumps. The piezoelectric material is actuated by an external voltage source to generate cavitation, which disrupts tissue and/or lyses cells, in particular by a modulated alternative external voltage. The invention further provides a method of disrupting tissue and/or lysing cells in a device comprising the steps: loading a sample and reagents; actuating a piezoelectric material; obtaining disrupted tissue and/or lysed cells; and recovering the eluate.

Abstract: A micro-pump having a first layer, a second layer and an intermediate flexible layer is disclosed. The first layer and second layer may be of moldable plastics. The intermediate layer may be a substantially flat PDMS membrane layer having an inlet hole and an outlet hole. The first layer and the second layer are disposed on either side of the intermediate layer to define a pumping chamber that encloses an actuatable portion of the intermediate layer and valve seats that abut the inlet hole and the outlet hole of the intermediate layer. The actuatable portion is moveable to increase and reduce the volume of the pumping chamber to allow pressure to lift the respective intermediate layer portions surrounding the inlet hole and the outlet hole to thereby draw fluid and expel fluid from the pumping chamber respectively.

Abstract: An integrated coil assembly (10), a multi-phase linear motor having the integrated coil assembly (10) and a method (100) for forming the integrated coil assembly (10) are described. The integrated coil assembly (10) has multi-phase coils with each multi-phase coil (20) having a number of coil loops based upon the number of electrical phases of current required by the multi-phase linear motor. The coil loops of different multi-phase coils are interweaved at two opposing portions (11,12) and are substantially parallel at two other opposing portions (13,14). In the method (100), different wire dispensers wind coil loops for different electrical phase for each multi-phase coil (20). However, the same wire dispenser winds coil loops that are for the same electrical phase for different multi-phase coils (20). The coil loops for each multi-phase coil (20) are wound before the coil loops of another multi-phase coil (20) are wound.

Abstract: An integrated coil assembly (10), a multi-phase linear motor having the integrated coil assembly (10) and a method (100) for forming the integrated coil assembly (10) are described. The integrated coil assembly (10) has multi-phase coils with each multi-phase coil (20) having a number of coil loops based upon the number of electrical phases of current required by the multi-phase linear motor. The coil loops of different multi-phase coils are interweaved at two opposing portions (11,12) and are substantially parallel at two other opposing portions (13,14). In the method (100), different wire dispensers wind coil loops for different electrical phase for each multi-phase coil (20). However, the same wire dispenser winds coil loops that are for the same electrical phase for different multi-phase coils (20). The coil loops for each multi-phase coil (20) are wound before the coil loops of another multi-phase coil (20) are wound.