Abstract: An injector including a syringe arranged along a longitudinal axis, a removable cover for removable engagement with the syringe and a cover removal assembly including an outer portion which is engagable by a user and is movable axially in a cover disengagement direction along an axial travel path with respect to the longitudinal axis and an inner portion which includes at least one engagement portion which is engagable with the removable cover, whereby axial movement of the inner portion in the cover disengagement direction removes the removable cover from the syringe, at least one of the outer portion and the inner portion being configured such as to provide an axially floating lost motion engagement between the outer portion and the inner portion.

Abstract: A syringe assembly, comprising a syringe barrel having a forward end and a rearward end and being arranged along a longitudinal axis; a restricting element, moveably supported onto a portion of the syringe assembly and positionable in one of an injection disabling position and an injection enabling position in different operative orientations of the syringe assembly; a plunger rod assembly displaceable within the syringe barrel and operatively coupled with the restricting element; the plunger rod assembly having a restricting feature adapted to cooperate with the restricting element, such that when the restricting element in the injection disabling position, the plunger rod assembly is permitted to be displaced axially forwardly only up to a certain longitudinal extent relative to the syringe barrel and when the restricting element is in the injection enabling position, the plunger rod assembly is permitted to be further displaced axially forwardly relative to the syringe barrel.

Abstract: A syringe assembly, comprising a syringe barrel having a forward end and a rearward end and being arranged along a longitudinal axis; a restricting element, moveably supported onto a portion of the syringe assembly and positionable in one of an injection disabling position and an injection enabling position in different operative orientations of the syringe assembly; a plunger rod assembly displaceable within the syringe barrel and operatively coupled with the restricting element; the plunger rod assembly having a restricting feature adapted to cooperate with the restricting element, such that when the restricting element in the injection disabling position, the plunger rod assembly is permitted to be displaced axially forwardly only up to a certain longitudinal extent relative to the syringe barrel and when the restricting element is in the injection enabling position, the plunger rod assembly is permitted to be further displaced axially forwardly relative to the syringe barrel.

Abstract: A dual chamber syringe, comprising a syringe barrel having a forward end, a rearward end and at least one bypass protrusion arranged along the longitudinal extent of the syringe barrel; a finger grip element coupled to the rearward end of the syringe barrel, the finger grip comprises at least one protrusion extending radially inwardly from an inner surface thereof; a plunger rod operatively coupled with the finger grip element; a guiding track is formed on the plunger rod and comprises a helical track portion and a longitudinal track portion; and wherein upon relative displacement of the plunger rod and said finger grip element, the at least one protrusion is guided along the guiding track.

Abstract: A dual chamber injection system, comprising a guiding element arranged along a longitudinal axis and configured to at least partially contain a medicament container, the guiding element defines an inner surface and at least one protrusion extending radially inwardly therefrom; a plunger rod assembly, comprising a plunger outer portion arranged along the longitudinal axis and a plunger inner portion arranged concentrically within the plunger outer portion and having at least one guiding groove arranged on an outer surface of the plunger inner portion; the plunger outer portion is disposed externally relative to the guiding element; the plunger inner portion is at least partially received into the guiding element; and wherein the plunger rod assembly is displaceable relative to the guiding element and the displacement is guided by engagement of the at least one protrusion with the at least one guiding groove.

Abstract: A medical container, comprising a barrel having an inner surface partially treated with a friction reducing agent, the barrel having at least one substance chamber and wherein the at least one substance chamber defines a portion of the inner surface, which is not treated with the friction reducing agent.

Abstract: An automatically retracting safety needle assembly configured to receive a syringe. The assembly has distal and proximal ends, and comprises: a housing, with internal housing (IH), and a base wall. A moving sleeve (MOS): at least partially within the IH; having a flange wall; axially movable. A biasing element (BE), within the IH, biasing the MOS proximally. A syringe, receiving a plunger rod; movable axially within the IH, and coupled to the MOS. An activation fork (AF), partially disposed within the IH. AF has a guiding arm coupled with the IH and the MOS; preventing motion of the MOS during non-deployment state. An automatic retraction mechanism, retracting the syringe after injection. Deployment: advance plunger rod and the AF axially (distally), until AF guiding arm allows proximal movement of the MOS, retracting the syringe. Distal advancement of plunger rod is constant without an abrupt increase in resistive force; allowing safe disposal.

Abstract: A dual chamber syringe, comprising a syringe barrel having a forward end, a rearward end and at least one bypass protrusion arranged along the longitudinal extent of the syringe barrel; a finger grip element coupled to the rearward end of the syringe barrel, the finger grip comprises at least one protrusion extending radially inwardly from an inner surface thereof; a plunger rod operatively coupled with the finger grip element; a guiding track is formed on the plunger rod and comprises a helical track portion and a longitudinal track portion; and wherein upon relative displacement of the plunger rod and said finger grip element, the at least one protrusion is guided along the guiding track.

Abstract: A dual chamber syringe, comprising a syringe barrel having a forward end, a rearward end and at least one bypass protrusion arranged along the longitudinal extent of the syringe barrel; a finger grip element coupled to the rearward end of the syringe barrel, the finger grip comprises at least one protrusion extending radially inwardly from an inner surface thereof; a plunger rod operatively coupled with the finger grip element; a guiding track is formed on the plunger rod and comprises a helical track portion and a longitudinal track portion; and wherein upon relative displacement of the plunger rod and said finger grip element, the at least one protrusion is guided along the guiding track.

Abstract: An automatically retracting safety needle assembly configured to receive a syringe. The assembly has distal and proximal ends, and comprises: a housing, with internal housing (IH), and a base wall. A moving sleeve (MOS): at least partially within the IH; having a flange wall; axially movable. A biasing element (BE), within the IH, biasing the MOS proximally. A syringe, receiving a plunger rod; movable axially within the IH, and coupled to the MOS. An activation fork (AF), partially disposed within the IH. AF has a guiding arm coupled with the IH and the MOS; preventing motion of the MOS during non-deployment state. An automatic retraction mechanism, retracting the syringe after injection. Deployment: advance plunger rod and the AF axially (distally), until AF guiding arm allows proximal movement of the MOS, retracting the syringe. Distal advancement of plunger rod is constant without an abrupt increase in resistive force; allowing safe disposal.

Abstract: A syringe assembly, comprising a syringe barrel having a forward end and a rearward end and being arranged along a longitudinal axis; a restricting element, moveably supported onto a portion of the syringe assembly and positionable in one of an injection disabling position and an injection enabling position in different operative orientations of the syringe assembly; a plunger rod assembly displaceable within the syringe barrel and operatively coupled with the restricting element; the plunger rod assembly having a restricting feature adapted to cooperate with the restricting element, such that when the restricting element in the injection disabling position, the plunger rod assembly is permitted to be displaced axially forwardly only up to a certain longitudinal extent relative to the syringe barrel and when the restricting element is in the injection enabling position, the plunger rod assembly is permitted to be further displaced axially forwardly relative to the syringe barrel.

Abstract: Exemplary embodiments provide a needle shield remover that reliably engages with a distal cap of an automatic injection device and with one or more needle shields coupled to a syringe of the device. When a user removes the distal cap, the needle shield remover reliably removes the needle shields (e.g., a soft needle shield and a rigid needle shield) from the syringe, thereby exposing the injection needle for performing an injection. In an exemplary assembly method, a needle shield remover is engaged to a needle shield coupled to a syringe, prior to insertion of the syringe and needle shield remover assembly into a housing of the device. This exemplary assembly method allows visual inspection, outside the housing of the device, to ensure that the needle shield remover is correctly and reliably engaged to the needle shield before the syringe and needle shield remover assembly is inserted into the housing.

Abstract: A dual chamber syringe, comprising a syringe barrel having a forward end, a rearward end and at least one bypass protrusion arranged along the longitudinal extent of the syringe barrel; a finger grip element coupled to the rearward end of the syringe barrel, the finger grip comprises at least one protrusion extending radially inwardly from an inner surface thereof; a plunger rod operatively coupled with the finger grip element; a guiding track is formed on the plunger rod and comprises a helical track portion and a longitudinal track portion; and wherein upon relative displacement of the plunger rod and said finger grip element, the at least one protrusion is guided along the guiding track.

Abstract: An injector including a syringe arranged along a longitudinal axis, a removable cover for removable engagement with the syringe and a cover removal assembly including an outer portion which is engagable by a user and is movable axially in a cover disengagement direction along an axial travel path with respect to the longitudinal axis and an inner portion which includes at least one engagement portion which is engagable with the removable cover, whereby axial movement of the inner portion in the cover disengagement direction removes the removable cover from the syringe, at least one of the outer portion and the inner portion being configured such as to provide an axially floating lost motion engagement between the outer portion and the inner portion.

Abstract: An injector including a syringe arranged along a longitudinal axis, a removable cover for removable engagement with the syringe and a cover removal assembly including an outer portion which is engagable by a user and is movable axially in a cover disengagement direction along an axial travel path with respect to the longitudinal axis and an inner portion which includes at least one engagement portion which is engagable with the removable cover, whereby axial movement of the inner portion in the cover disengagement direction removes the removable cover from the syringe, at least one of the outer portion and the inner portion being configured such as to provide an axially floating lost motion engagement between the outer portion and the inner portion.

Abstract: Exemplary embodiments provide a needle shield remover that reliably engages with a distal cap of an automatic injection device and with one or more needle shields coupled to a syringe of the device. When a user removes the distal cap, the needle shield remover reliably removes the needle shields (e.g., a soft needle shield and a rigid needle shield) from the syringe, thereby exposing the injection needle for performing an injection. In an exemplary assembly method, a needle shield remover is engaged to a needle shield coupled to a syringe, prior to insertion of the syringe and needle shield remover assembly into a housing of the device. This exemplary assembly method allows visual inspection, outside the housing of the device, to ensure that the needle shield remover is correctly and reliably engaged to the needle shield before the syringe and needle shield remover assembly is inserted into the housing.

Abstract: Exemplary embodiments provide a needle shield remover that reliably engages with a distal cap of an automatic injection device and with one or more needle shields coupled to a syringe of the device. When a user removes the distal cap, the needle shield remover reliably removes the needle shields (e.g., a soft needle shield and a rigid needle shield) from the syringe, thereby exposing the injection needle for performing an injection. In an exemplary assembly method, a needle shield remover is engaged to a needle shield coupled to a syringe, prior to insertion of the syringe and needle shield remover assembly into a housing of the device. This exemplary assembly method allows visual inspection, outside the housing of the device, to ensure that the needle shield remover is correctly and reliably engaged to the needle shield before the syringe and needle shield remover assembly is inserted into the housing.

Abstract: The disclosure relates to needle shielding devices which cover injector needle to prevent accidental needle pricks and reduce user fear, before, during and following injection. More particularly, the disclosure relates to sheathed needle actuation devices configured to provide a predetermined force-distance profile on the shield during injection.

Abstract: A device for delivering an active agent to a tissue (100), comprising; a housing (10) including a reservoir (20) for containing said active agent; a delivery tip (35) being in fluid communication with said reservoir; and, a delivery mechanism (40) capable of delivering a predetermined amount of said active agent and releasing the same upon contact between said delivery tip and said tissue.

Abstract: Exemplary embodiments provide a needle shield remover that reliably engages with a distal cap of an automatic injection device and with one or more needle shields coupled to a syringe of the device. When a user removes the distal cap, the needle shield remover reliably removes the needle shields (e.g., a soft needle shield and a rigid needle shield) from the syringe, thereby exposing the injection needle for performing an injection. In an exemplary assembly method, a needle shield remover is engaged to a needle shield coupled to a syringe, prior to insertion of the syringe and needle shield remover assembly into a housing of the device. This exemplary assembly method allows visual inspection, outside the housing of the device, to ensure that the needle shield remover is correctly and reliably engaged to the needle shield before the syringe and needle shield remover assembly is inserted into the housing.