Patents by Inventor Gyula Hadlaczky

Gyula Hadlaczky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of producing a cell carrying an excess of mammalian centromeres and the cell line carrying an excess of mammalian centromeres
    Patent number: 5891691
    Abstract: DNA fragments and methods for obtaining them are disclosed which when put into mammalian cells together with a dominant marker gene are able to form functional centromeres. The sequences can be used to generate probes for these centromeres. Cell lines containing the functional centromeres are also provided. Methods are taught for isolating mammalian centromeric DNA as well as for producing cell lines carrying an excess of mammalian centromeres linked to a dominant selectable marker gene.
    Type: Grant
    Filed: October 21, 1996
    Date of Patent: April 6, 1999
    Assignee: The Biological Research Center of the Hungarian Academy of Sciences
    Inventor: Gyula Hadlaczky
  • Method of producing a cell carrying an excess of mammalian centromeres
    Patent number: 5712134
    Abstract: DNA fragments and methods for obtaining them are disclosed which when put into mammalian cells together with a dominant marker gene are able to generate functional centromeres. The sequences can be used to form probes for these centromeres. Cell lines containing the functional centromeres are also provided. Methods are taught for isolating mammalian centromeric DNA as well as for producing cell lines carrying an excess of mammalian centromeres linked to a dominant selectable marker gene.
    Type: Grant
    Filed: January 19, 1995
    Date of Patent: January 27, 1998
    Assignee: The Biological Research Center of the Hungarian Academy of Sciences
    Inventor: Gyula Hadlaczky
  • Mammalian artificial chromosomes
    Patent number: 5288625
    Abstract: Non-human cell lines are disclosed which contain functional centromeres comprising human DNA sequences linked to a dominant marker gene. The centromeres are carried on stable chromosomes which carry no centromeres other than those comprising human DNA sequences. The cell lines can be used to isolate the chromosomes as well as for use in inserting genes into mammalian cells. Methods are taught for generating such cell lines from cell lines carrying dicentric chromosomes.
    Type: Grant
    Filed: September 13, 1991
    Date of Patent: February 22, 1994
    Assignee: Biologic Research Center of the Hungarian Academy of Sciences
    Inventor: Gyula Hadlaczky