Patents by Inventor H. Michael Shepard

H. Michael Shepard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF
    Publication number: 20250197832
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Application
    Filed: March 5, 2025
    Publication date: June 19, 2025
    Inventors: Ge WEI, H. Michael SHEPARD, Qiping ZHAO, Robert James CONNOR
  • PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF
    Publication number: 20250197835
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Application
    Filed: March 5, 2025
    Publication date: June 19, 2025
    Inventors: Ge WEI, H. Michael SHEPARD, Qiping ZHAO, Robert James Cannor
  • PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF
    Publication number: 20250197833
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Application
    Filed: March 5, 2025
    Publication date: June 19, 2025
    Inventors: Ge Wei, H. Michael Shepard, Qiping Zhao, Robert James Connor
  • PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF
    Publication number: 20250197836
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Application
    Filed: March 5, 2025
    Publication date: June 19, 2025
    Inventors: Ge WEI, H. Michael Shepard, Qiping Zhao, Robert James Connor
  • PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF
    Publication number: 20250197834
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Application
    Filed: March 5, 2025
    Publication date: June 19, 2025
    Inventors: Ge Wei, H. Michael Shepard, Qiping Zhao, Robert James Connor
  • PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF
    Publication number: 20250154488
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Application
    Filed: June 28, 2024
    Publication date: May 15, 2025
    Inventors: Ge WEI, H. Michael SHEPARD, Qiping ZHAO, Robert James CONNOR
  • PH20 polypeptide variants, formulations and uses thereof
    Patent number: 12264345
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Grant
    Filed: July 19, 2024
    Date of Patent: April 1, 2025
    Assignee: HALOZYME, INC.
    Inventors: Ge Wei, H. Michael Shepard, Qiping Zhao, Robert James Connor
  • PH20 POLYPEPTIDE VARIANTS, FORMULATIONS AND USES THEREOF
    Publication number: 20250051747
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Application
    Filed: October 22, 2024
    Publication date: February 13, 2025
    Inventors: Ge Wei, H. Michael Shepard, Qiqing Zhao, Robert James Connor
  • PH20 polypeptide variants, formulations and uses thereof
    Patent number: 12195773
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Grant
    Filed: May 9, 2024
    Date of Patent: January 14, 2025
    Assignee: HALOZYME, INC.
    Inventors: Ge Wei, H. Michael Shepard, Qiping Zhao, Robert James Connor
  • PH20 polypeptide variants, formulations and uses thereof
    Patent number: 12152262
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Grant
    Filed: June 23, 2023
    Date of Patent: November 26, 2024
    Assignee: HALOZYME, INC.
    Inventors: Ge Wei, H. Michael Shepard, Qiping Zhao, Robert James Connor
  • PH20 polypeptide variants, formulations and uses thereof
    Patent number: 12123035
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Grant
    Filed: December 19, 2022
    Date of Patent: October 22, 2024
    Assignee: Halozyme, Inc.
    Inventors: Ge Wei, H. Michael Shepard, Qiping Zhao, Robert James Connor
  • PH20 polypeptide variants, formulations and uses thereof
    Patent number: 12110520
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Grant
    Filed: December 19, 2022
    Date of Patent: October 8, 2024
    Assignee: Halozyme, Inc.
    Inventors: Ge Wei, H. Michael Shepard, Qiping Zhao, Robert James Connor
  • PH20 polypeptide variants, formulations and uses thereof
    Patent number: 12104185
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Grant
    Filed: March 8, 2024
    Date of Patent: October 1, 2024
    Assignee: Halozyme, Inc.
    Inventors: Ge Wei, H. Michael Shepard, Qiping Zhao, Robert James Connor
  • PH20 polypeptide variants, formulations and uses thereof
    Patent number: 12104184
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Grant
    Filed: December 19, 2022
    Date of Patent: October 1, 2024
    Assignee: Halozyme, Inc.
    Inventors: Ge Wei, H. Michael Shepard, Qiping Zhao, Robert James Connor
  • PH20 Polypeptide Variants, Formulations and Uses Thereof
    Publication number: 20240318158
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Application
    Filed: May 9, 2024
    Publication date: September 26, 2024
    Inventors: Ge WEI, H. Michael SHEPARD, Qiping Zhao, Robert James CONNOR
  • PH20 polypeptide variants, formulations and uses thereof
    Patent number: 12091692
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Grant
    Filed: May 21, 2021
    Date of Patent: September 17, 2024
    Assignee: HALOZYME, INC.
    Inventors: Ge Wei, H. Michael Shepard, Qiping Zhao, Robert James Connor
  • PH20 polypeptide variants with a modification at position 309 of the PH20 polypeptide and a method of making thereof
    Patent number: 12077791
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Grant
    Filed: June 22, 2023
    Date of Patent: September 3, 2024
    Assignee: HALOZYME, INC.
    Inventors: Ge Wei, H. Michael Shepard, Qiping Zhao, Robert James Connor
  • PH20 polypeptide variants, formulations and uses thereof
    Patent number: 12060590
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Grant
    Filed: December 19, 2022
    Date of Patent: August 13, 2024
    Assignee: HALOZYME, INC.
    Inventors: Ge Wei, H. Michael Shepard, Qiping Zhao, Robert James Connor
  • PH20 polypeptide variants, formulations and uses thereof
    Patent number: 12054758
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Grant
    Filed: December 15, 2022
    Date of Patent: August 6, 2024
    Assignee: HALOZYME, INC.
    Inventors: Ge Wei, H. Michael Shepard, Qiping Zhao, Robert James Connor
  • PH20 polypeptide variants, formulations and uses thereof
    Patent number: 12049652
    Abstract: Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
    Type: Grant
    Filed: December 12, 2022
    Date of Patent: July 30, 2024
    Assignee: HALOZYME, INC.
    Inventors: Ge Wei, H. Michael Shepard, Qiping Zhao, Robert James Connor