Patents by Inventor Hagen-Heinrich Hennies

Hagen-Heinrich Hennies has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Saturated and unsaturated heteroarylcycloalkylmethyl amines as anti-depressants
    Publication number: 20060025456
    Abstract: Saturated and unsaturated heteroarylcycloalkylmethyl-amine compounds corresponding to formula I, processes for their preparation, pharmaceutical formulations comprising these compounds and the use of saturated and unsaturated heteroarylcycloalkylmethyl-amines for the preparation of pharmaceutical formulations. pharmaceutical formulations and related methods of treatment or prophylaxis of certain condition, especially depression and/or pain, are also disclosed.
    Type: Application
    Filed: June 20, 2005
    Publication date: February 2, 2006
    Applicant: Gruenenthal GmbH
    Inventors: Petra Bloms-Funke, Claudia Puetz, Ivars Graudums, Achim Kless, Carsten Griebel, Hagen-Heinrich Hennies, Dagmar Kaulartz, Sabine Reinardy, Derek Saunders, Klaus Schiene, Bernd Sundermann, Werner Englberger, Oswald Zimmer
  • Substituted 5-aminomethyl-1H-pyrrole-2-carboxamides
    Publication number: 20050288342
    Abstract: 5-aminomethyl-1H-pyrrole-2-carboxylic acid amide compounds corresponding to formula I and processes for the production thereof. Pharmaceutical preparations containing these compounds and the use of these compounds for the production of pharmaceutical preparations and in related treatment methods.
    Type: Application
    Filed: June 20, 2005
    Publication date: December 29, 2005
    Applicant: Gruenenthal GmbH
    Inventors: Beatrix Merla, Corinna Sundermann, Utz-Peter Jagusch, Werner Englberger, Hagen-Heinrich Hennies, Babette-Yvonne Kögel
  • Pharmaceutical preparations containing substituted 2,5-diaminomethyl-1H-pyrroles
    Publication number: 20050272782
    Abstract: Pharmaceutical preparations containing substituted 2,5-diaminomethyl-1H-pyrrole compounds corresponding to formula I, and the use of these compounds for the production of pharmaceutical preparations and in related treatment methods.
    Type: Application
    Filed: June 20, 2005
    Publication date: December 8, 2005
    Applicant: Gruenenthal GmbH
    Inventors: Beatrix Merla, Corinna Sundermann, Utz-Peter Jagusch, Werner Englberger, Hagen-Heinrich Hennies
  • Substituted C-imidazo[1,2-a]pyridin-3yl-methylamines
    Publication number: 20050239823
    Abstract: Novel C-imidazo[1,2-?]pyridin-3-yl-methylamine compounds corresponding to formula I, wherein R1-R6 have the meanings provided in the description. Pharmaceutical compositions containing these compounds are also provided, as well as methods of using these compounds for treating or inhibiting various illnesses or other conditions.
    Type: Application
    Filed: April 8, 2005
    Publication date: October 27, 2005
    Applicant: Gruenenthal Gmbh
    Inventors: Stefan Oberboersch, Bernd Sundermann, Corinna Sundermann, Hagen-Heinrich Hennies
  • Substituted C-imiadazol[1,2-a] pyridin-3-yl-methylamines
    Publication number: 20050239822
    Abstract: Substituted C-imidazo [1,2-a]pyridine-3-yl methylamines and physiologically acceptable salts thereof, a method for the production thereof, pharmaceutical compositions containing these compounds, and pharmaceutical uses thereof, e.g., as NO synthase inhibitors.
    Type: Application
    Filed: April 7, 2005
    Publication date: October 27, 2005
    Applicant: Gruenenthal GmbH
    Inventors: Hagen-Heinrich Hennies, Corinna Sundermann, Bernd Sundermann, Stefan Oberboersch
  • Use of substituted gamma-lactone compounds as pharmaceutical preparations
    Patent number: 6943181
    Abstract: The invention relates to the use of substituted gamma-lactone compounds in the production of medicines for treating migraines, septic shock, neurodegenerative diseases, such as multiple sclerosis, Parkinsons, Alzheimers or Huntingtons disease, inflammations and related pain, cerebral ischaemia, diabetes, meningitis, arteriosclerosis, cancer, mycosis, or for healing wounds.
    Type: Grant
    Filed: January 5, 2004
    Date of Patent: September 13, 2005
    Assignee: Grunenthal GmbH
    Inventors: Corinna Sundermann, Bernd Sundermann, Michael Przewosny, Hagen-Heinrich Hennies
  • 2-Pyrrolidin-2-yl-[1,3,4]-oxadiazole compounds and their use as anti-depressants
    Publication number: 20050187260
    Abstract: Substituted 2-pyrrolidin-2-yl compounds corresponding to formula I a method for their production, pharmaceutical compositions containing them, and methods of using them, especially for treating pain and/or depression.
    Type: Application
    Filed: February 28, 2005
    Publication date: August 25, 2005
    Applicant: Gruenenthal GmbH
    Inventors: Hagen-Heinrich Hennies, Corinna Sundermann, Helmut Buschmann, Bernd Sundermann
  • Substituted 4-aminocyclohexanols
    Publication number: 20050187220
    Abstract: Substituted 4-aminocyclohexanols, processes for their preparation, pharmaceutical compositions comprising these compounds and to the use of substituted 4-aminocyclohexanols in the preparation of pharmaceutical compositions for the treatment of various indications, especially pain as well as the treatment of these indications.
    Type: Application
    Filed: September 23, 2004
    Publication date: August 25, 2005
    Applicant: Gruenenthal GmbH
    Inventors: Bernd Sundermann, Hagen-Heinrich Hennies, Werner Englberger, Babette-Yvonne Koegel
  • 1-Phenyl-2-dimethylaminomethyl cyclohexane compounds and therapies for depressive symptoms, pain and incontinence
    Publication number: 20050182131
    Abstract: The invention relates to metabolites of [2-(3-methoxyphenyl)-cyclohexylmethyl]-dimethylamine as free bases and/or in the form of physiologically acceptable salts, corresponding medicaments, the use of [2-(3-methoxyphenyl)-cyclohexylmethyl]-dimethylamine and the metabolites thereof for producing a medicament used for treating depression, and related methods of treating depression.
    Type: Application
    Filed: January 19, 2005
    Publication date: August 18, 2005
    Applicant: Gruenenthal GmbH
    Inventors: Elmar Friderichs, Wolfgang Strassburger, Ulrich Jahnel, Derek Saunders, Hagen-Heinrich Hennies, Werner Englberger, Helmut Buschmann, Joerg Holenz, Oswald Zimmer
  • N, N'-disubstituted piperazine compounds and their use as analgesics
    Publication number: 20050026926
    Abstract: N,N?-disubstituted piperazine compounds, processes for the production thereof, and pharmaceutical preparations containing these compounds. The use of N,N?-disubstituted piperazine compounds for the production of pharmaceutical preparations and in related methods of treatment.
    Type: Application
    Filed: June 14, 2004
    Publication date: February 3, 2005
    Applicant: Gruenenthal GmbH
    Inventors: Heinz Uragg, Corinne Maul, Helmut Buschmann, Bernd Sundermann, Hagen-Heinrich Hennies
  • Pharmaceutical preparations comprising substituted beta-aminoalcohols
    Publication number: 20050020691
    Abstract: Pharmaceutical compositions containing substituted aminoalcohols, the use of preparations containing substituted aminoalcohols for treatment of conditions such as pain, emesis, neurotropic conditions, cardiovascular diseases, urinary incontinence, diarrhea, pruritus, alcohol or drug dependency, inflammation, depression, decreased vigilance, or depressed libido, as well as 2-(aminomethyl)cycloalkane-1-ol compounds and a process for their preparation.
    Type: Application
    Filed: June 14, 2004
    Publication date: January 27, 2005
    Applicant: Gruenenthal GmbH
    Inventors: Heinz Uragg, Corinna Maul, Helmut Buschmann, Bernd Sundermann, Hagen-Heinrich Hennies
  • Substituted 2-pyrrolidine-2-yl-1H-indole compounds
    Publication number: 20050014815
    Abstract: Novel 2-pyrrolidin-2-yl-1H-indole compounds corresponding to formula (I) wherein R1, R2, R3 and R4 have the meanings given in the description, and pharmaceutical compositions containing these compounds, as well as processes for the preparation of such compounds and intermediate products of this process, and related methods of treatment.
    Type: Application
    Filed: June 7, 2004
    Publication date: January 20, 2005
    Applicant: GRUENENTHAL GMBH
    Inventors: Corinna Sundermann, Bernd Sundermann, Helmut Buschmann, Hagen-Heinrich Hennies
  • Substituted 4-aminocyclohexanols
    Publication number: 20040236104
    Abstract: Substituted 4-aminocyclohexanols, methods of producing the same, pharmaceuticals containing these compounds, the use of substituted 4-aminocyclohexanols for producing pharmaceutical compositions for the treatment of various indications, in particular pain, and for related treatment methods.
    Type: Application
    Filed: January 16, 2004
    Publication date: November 25, 2004
    Applicant: Gruenenthal Gmbh
    Inventors: Bernd Sundermann, Hagen-Heinrich Hennies, Werner Englberger, Stephan Wnendt
  • Substituted 4-aminocyclohexanol compounds
    Publication number: 20040214822
    Abstract: 4-aminocyclohexanol compounds, processes for their preparation, pharmaceutical formulations comprising these compounds and the use of substituted 4-aminocyclohexanol compounds for the preparation of pharmaceutical formulations and for the treatment of diverse indications, including, without limitation, pain.
    Type: Application
    Filed: January 16, 2004
    Publication date: October 28, 2004
    Applicant: Gruenenthal GmbH
    Inventors: Bernd Sundermann, Hagen-Heinrich Hennies, Babette-Yvonne Koegel, Stephan Wnendt
  • Substituted 1-oxa-2,8-diaza-spiro[4,5]dec-2-ene derivatives and related treatment methods
    Publication number: 20040192916
    Abstract: Substituted 1-oxa-2,8-diaza-spiro[4,5]dec-2-ene compounds and processes for their production, the use thereof for producing pharmaceutical compositions, pharmaceutical compositions containing these compounds and methods of treatment using these compounds.
    Type: Application
    Filed: December 24, 2003
    Publication date: September 30, 2004
    Applicant: Gruenenthal GmbH
    Inventors: Heinrich Helmut Buschmann, Guenter Werner Englberger, Tieno Germann, Hagen-Heinrich Hennies, Corinna Maul, Bernd Sundermann, Joerg Holenz
  • Use of substituted gamma-lactone compounds as pharmaceutical preparations
    Publication number: 20040176394
    Abstract: The invention relates to the use of substituted gamma-lactone compounds in the production of medicines for treating migraines, septic shock, neurodegenerative diseases, such as multiple sclerosis, Parkinsons, Alzheimers or Huntingtons disease, inflammations and related pain, cerebral ischaemia, diabetes, meningitis, arteriosclerosis, cancer, mycosis, or for healing wounds.
    Type: Application
    Filed: January 5, 2004
    Publication date: September 9, 2004
    Inventors: Corinna Maul Sundermann, Bernd Sundermann, Michael Przewosny, Hagen-Heinrich Hennies
  • Substituted cyclohexane-1,4-diamine compounds
    Publication number: 20040162287
    Abstract: Substituted cyclohexane-1,4-diamine compounds, methods for production thereof, pharmaceutical compositions comprising these compounds and methods of treatment using these compounds.
    Type: Application
    Filed: November 10, 2003
    Publication date: August 19, 2004
    Applicant: GRUENENTHAL GmbH
    Inventors: Bernd Sundermann, Hagen-Heinrich Hennies, Werner Englberger, Babette-Yvonne Koegel
  • Utilization of substituted imidazo[1,2-a]-pyridine compounds in pharmaceutical formulations
    Publication number: 20040142961
    Abstract: Methods of using pharmaceutical formulations with imidazo[1,2-a]-pyridine compounds as active ingredients to inhibit nitric oxide synthase are disclosed. Treatments of certain conditions using imidazo[1,2-a]-pyridine compounds are also disclosed.
    Type: Application
    Filed: October 3, 2003
    Publication date: July 22, 2004
    Inventors: Corinna Sundermann, Hagen-Heinrich Hennies, Bernd Sundermann
  • Utilization of substituted imidazo [1,2-A]-pyridin-3-yl-amide and imidazo [1,2-A]-pyridin-3-yl-amine compounds in pharmaceutical formulations
    Publication number: 20040122044
    Abstract: Methods of using pharmaceutical formulations with imidazo[1,2-a]-pyridin-3-yl-amide or -amine compounds as active ingredients to inhibit nitric oxide synthase are disclosed. Treatments of certain conditions using imidazo[1,2-a]-pyridin-3-yl-amide or -amine compounds are also disclosed, as are processes for preparing imidazo[1,2-a]-pyridin-3-yl-amide or -amine compounds.
    Type: Application
    Filed: October 3, 2003
    Publication date: June 24, 2004
    Inventors: Corinna Maul, Hagen-Heinrich Hennies, Bernd Sundermann
  • Tert -butyl-(7-methyl-imidazol [1,2-a]pyridin-3-yl)-amine derivatives
    Patent number: 6703404
    Abstract: A Tert.-butyl-(7-methyl-imidazo[1,2-a]pyridin-3-yl)-amine derivatives of Formula I: wherein the pharmaceutically acceptable salts, methods of making and method of use, in particular for the treatment of migraine.
    Type: Grant
    Filed: April 8, 2002
    Date of Patent: March 9, 2004
    Assignee: Gruenenthal GmbH
    Inventors: Corinna Maul, Bernd Sundermann, Hagen-Heinrich Hennies, Johannes Schneider, Matthias Gerlach