Patents by Inventor Hagen Jaedicke
Hagen Jaedicke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7687632Abstract: Process for the preparation of substituted pyridine derivatives of formula (I) comprising reaction of a ?-?-unsaturated carbonyl compound of formula (II) R3—C(O)—C(R1)?C(R2)-G with a Wittig reagent or Horner-Wadsworth-Emmons reagent in the presence of a base and optionally subsequent cyclization.Type: GrantFiled: December 22, 2004Date of Patent: March 30, 2010Assignee: Dow AgroSciences LLCInventors: Joachim Gebhardt, Norbert Götz, Hagen Jaedicke, Guido Mayer, Michael Rack
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Patent number: 7488828Abstract: 4-Trifluoromethyl-2(1H)-pyridinone is prepared by reaction of 4-alkoxy-1,1,1-trifluorobut-3-en-2-one or 4,4-dialkoxy-1,1,1-trifluorobutan-2-one with a trialkyl phosphonoacetate followed by cyclization.Type: GrantFiled: June 24, 2005Date of Patent: February 10, 2009Assignee: Dow AgroSciences LLCInventors: Christopher Thomas Hamilton, Michael Frederick Gullo, Michael Allen Gonzalez, Gary Alan Roth, David Bruce Gorman, Joachim Gebhardt, Norbert Götz, Hagen Jaedicke, Guido Mayer, Michael Rack
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Publication number: 20070249837Abstract: Process for the preparation of substituted pyridine derivatives of formula (I) comprising reaction of a ?-?-unsaturated carbonyl compound of formula (II) R3—C(O)—C(R1)?C(R2)-G ??(II) with a Wittig reagent or Horner-Wadsworth-Emmons reagent in the presence of a base and if subsequent cyclization.Type: ApplicationFiled: December 22, 2004Publication date: October 25, 2007Inventors: Joachim Gebhardt, Norbert Gotz, Hagen Jaedicke, Guido Mayer, Michael Rack
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Patent number: 6740774Abstract: A process for preparing N-acyl derivatives of the formula I, in which the substituents independently of one another have the following meanings: X is CH(OR3)2, COOR3; R1 is hydrogen, C1-C12-alkyl, aryl, unsubstituted or substituted; R2 is hydrogen, C1-C12-alkyl, aryl, unsubstituted or substituted; R3 is C1-C12-alkyl, which comprises reacting a carboxamide R1—CONH2 of the formula II with a glyoxal monoacetal derivative of the formula III, in the presence of a carboxylic acid R4—COOH of the formula IV where R4=C1-C12-alkyl, where the substituents R1 to R3 are as defined above, is described.Type: GrantFiled: August 16, 2000Date of Patent: May 25, 2004Assignee: BASF AktiengesellschaftInventors: Joachim Paust, Hansgeorg Ernst, Reinhard Kaczmarek, Hagen Jaedicke
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Patent number: 6476253Abstract: The present invention relates to a process for preparing monoacetylated hydroquinone compounds of the formula I, to the novel final products of the process and to a process for preparing the precursors.Type: GrantFiled: October 3, 2000Date of Patent: November 5, 2002Assignee: BASF AktiengesellschaftInventors: Karin Schein, Kai-Uwe Baldenius, Wolfgang Siegel, Rainer Stürmer, Detlef Ruff, Hagen Jaedicke
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Publication number: 20020127252Abstract: The invention relates to the use of chroman derivatives of the formula I, 1Type: ApplicationFiled: December 17, 2001Publication date: September 12, 2002Inventors: Klaus Kramer, Hagen Jaedicke, Axel Jentzsch
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Patent number: 6365758Abstract: A process for preparing tocopheryl esters or tocotrienyl esters by acid-catalyzed esterification of a tocopherol or a tocotrienol in a solvent while stirring at elevated temperature, which comprises a) carrying out the esterification with the appropriate carboxylic acid, b) carrying out the esterification with from 2.5 to 6 mol of the carboxylic acid in an aliphatic, cycloaliphatic or aromatic hydrocarbon boiling in the range from 80 to 200° C., or else with from 1.0 to 2.5 mol of the carboxylic acid in a mixture consisting of an aliphatic or cycloaliphatic hydrocarbon boiling in the range from 80 to 200° C.Type: GrantFiled: January 26, 1998Date of Patent: April 2, 2002Assignee: BASF AktiengesellschaftInventors: Joanna Linda von dem Bussche-Hünnefeld, Hagen Jaedicke, Guido Harms, Harald Laas
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Patent number: 6348593Abstract: A process for preparing folic acid, which comprises reacting a tetraalkoxypropanol of the general formula I, in which the substituents R are C1-C4-alkyl, with triaminopyrimidone of the formula II and p-aminobenzoyl-L-glutamic acid of the formula IIIType: GrantFiled: February 3, 2000Date of Patent: February 19, 2002Assignee: BASF AktiengesellschaftInventors: Jörg Botzem, Hagen Jaedicke, Michael John, Joachim Paust
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Patent number: 6329554Abstract: Process for the continuous preparation of unsaturated ketones of the formula I where the dashed line can be an additional C—C bond, R1 is an alkyl, and R2 is an aliphatic hydrocarbon having from 1 to 37 carbons, a cycloalkyl or a cycloalkylalkyl, by reacting an unsaturated alcohol of the formula II with an alkyl acetoacetate of the formula III where R3 is an alkyl having from 1 to 5 carbons, in the presence or organic aluminum compounds as catalyst.Type: GrantFiled: September 7, 1999Date of Patent: December 11, 2001Assignee: BASF AktiengesellschaftInventors: Carsten Oost, Manfred Stroezel, Heinz Etzrodt, Dietmar Weller, Bernhard Bockstiegel, Klaus Reimer, Gerd Kaibel, Hagen Jaedicke
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Patent number: 6307106Abstract: An improved process for preparing lower unsaturated ketones by reacting the corresponding &agr;,&bgr;-unsaturated alcohols with alkyl acetoacetates in a Carroll reaction in the presence of from 0.1 to 5 mol %, based on the alkyl acetoacetate to be reacted, of an organic aluminum compound as catalyst with elimination and continuous removal by distillation of the alkanol eliminated during the reaction from the alkyl acetoacetate in a reactor system with a fitted fractionation column, wherein A an &agr;,&bgr;-unsaturated alcohol which boils below 140° C. is introduced, in the absence of effective amounts of a solvent, together with the organic aluminum compound into the reaction vessel, B a reaction temperature which is as constant as possible between 170° C. and 250° C.Type: GrantFiled: November 15, 1999Date of Patent: October 23, 2001Assignee: BASF AktiengesellschaftInventors: Carsten Oost, Manfred Stroezel, Heinz Etzrodt, Dietmar Weller, Gerd Kaibel, Hagen Jaedicke
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Patent number: 6300524Abstract: The present invention relates to an improved process for preparing higher unsaturated ketones by reacting the corresponding &agr;,&bgr;-unsaturated alcohols with alkyl acetoacetates in a Carroll reaction , in a reactor system with fitted fractionation column, wherein A the &agr;,&bgr;-unsaturated alcohol is introduced into the reaction vessel together with the organic aluminum compound in the absence of effective amounts of a solvent, and the alkyl acetoacetate is metered into this mixture, B a reaction temperature which is as constant as possible at between 175° C. and 220° C., preferably between 180° C. and 200° C., is adjusted and C during the reaction the content of alkyl acetoacetate in the reaction mixture is adjusted to a value which is as constant as possible at between 1 and 3% by weight.Type: GrantFiled: November 15, 1999Date of Patent: October 9, 2001Assignee: BASF AktiengesellschaftInventors: Carsten Oost, Manfred Stroezel, Heinz Etzrodt, Dietmar Weller, Udo Rheude, Gerd Kaibel, Thomas Krug, Luise Spiske, Hagen Jaedicke
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Patent number: 6096907Abstract: A process for preparing chromanol derivatives of the formula I ##STR1## where n is from 1 to 10,R.sup.1, R.sup.2,R.sup.3, R.sup.4 independently of one another are hydrogen or C.sub.1 -C.sub.4 alkyl,R.sup.5 is hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.6 -C.sub.10 aryl, C.sub.7 -C.sub.18 aralkyl, C.sub.7 -C.sub.18 alkylaryl, C.sub.1 -C.sub.22 acyl, or a group protecting the hydroxyl,by reduction of the corresponding 4-oxochromanol derivatives of the formula II ##STR2## comprises reacting the 4-oxochromanol derivatives of the formula II with metallic zinc in the presence of an acid or an acid mixture.Compounds of the formula I having C.sub.1 -C.sub.22 acyl as radical R.sup.5 can also be prepared by the above-described reduction of the compounds of the formula II with hydrogen as radical R.sup.5 and simultaneous or subsequent esterification.Type: GrantFiled: September 14, 1999Date of Patent: August 1, 2000Assignee: BASF AktiengesellscahftInventors: Kai-Uwe Baldenius, Bernhard Bockstiegel, Hagen Jaedicke, Detlef Ruff, Carsten Siedenbiedel, Rainer Sturmer
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Patent number: 6051741Abstract: A process for preparing .gamma.,.delta.-unsaturated ketones of the general formula I ##STR1## by reacting an allyl alcohol of the general formula II ##STR2## in which R.sup.1 is H or a hydrocarbon radical having 1 to 20 carbon atoms, with diketene or an alkyl acetoacetate of the general formula III ##STR3## in which R.sup.2 is alkyl having 1 to 4 carbon atoms in an unmodified or modified Carroll reaction in the presence of an aluminum catalyst, wherein aluminum compounds which are stable liquids at room temperature, or a mixture of such aluminum compounds, which comprise at least one radical formed from an alkyl acetoacetate and 1 or 2 alkoxy radicals, or else comprise exclusively radicals formed from alkyl acetoacetates, which are esterified with sec-butanol or isobutanol, or else are esterified with at least two different alcohols, are used as aluminum catalyst.Type: GrantFiled: October 8, 1998Date of Patent: April 18, 2000Assignee: BASF AktiengesellschaftInventors: Heinz Etzrodt, Dietmar Weller, Carsten Oost, Hagen Jaedicke, Manfred Stroezel, Bernhard Bockstiegel, Lothar Laupichler, Klaus Reimer
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Patent number: 5874635Abstract: A process for preparing .gamma.,.delta.-unsaturated ketones bya) reacting vinylcarbinols or propargyl alcohols with alkyl acetoacetates or diketene andb) thermally rearranging the resulting acetoacetates in the presence or absence of an aluminum catalyst to .gamma.,.delta.-unsaturated ketones (Carroll reaction),wherein step a) and/or step b) is carried out in a cyclic carbonate of the formula I or a .gamma.-lactone of the formula II ##STR1## where R.sup.1, R.sup.2 and R.sup.3 are H, or lower alkyl and R.sup.4 is H, lower alkyl, phenyl or methoxymethyl, as solvent.Type: GrantFiled: November 5, 1997Date of Patent: February 23, 1999Assignee: BASF AktiengesellschaftInventors: Heinz Etzrodt, Manfred Stroezel, Dietmar Weller, Hagen Jaedicke
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Patent number: 5468883Abstract: A process for preparing dl-.alpha.-tocopherol or dl-.alpha.-tocopheryl acetate by acid-catalyzed reaction of 2,3,5-trimethylhydroquinone (TMH) with phytol or isophytol in a solvent at elevated temperature, with or without subsequent esterification of the resulting tocopherol with acetic anhydride, entails the reaction being carried out in the presence of a mixture of ortho-boric acid and certain aliphatic di- or tricarboxylic acids, preferably in the presence of a mixture of ortho-boric acid and oxalic acid.Type: GrantFiled: September 9, 1994Date of Patent: November 21, 1995Assignee: BASF AktiengesellschaftInventors: Paul Grafen, Hans Kiefer, Hagen Jaedicke
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Patent number: 5344995Abstract: An improved process for preparing cyclic acetals of 3-formyl-2-butenyltriphenylphosphonium chloride by acetalization of 3-formyl-2-butenyl acetate with an aliphatic 1,3-diol, conversion of the resulting 4-acetoxy acetal into the corresponding 4-hydroxy acetal, Vilsmeier chlorination to give the corresponding 4-chloro acetal and subsequent reaction with triphenylphosphine entails carrying out the first 3 steps in an aliphatic or cycloaliphatic hydrocarbon or mixture of hydrocarbons with 6-8 carbons and the reaction with triphenylphosphine in an alkanol with 1-3 carbons and/or in aliphatic or cycloaliphatic hydrocarbon with 6-8 carbons or a corresponding mixture of hydrocarbons. The process is particularly advantageous when conversion of the 4-acetoxy acetal into the 4-hydroxy acetal is carried out with an aqueous alkali metal hydroxide solution in the presence of phase-transfer catalysts, and the first three, or all four, reaction stages are carried out in the same C.sub.6 -C.sub.8 -hydrocarbon.Type: GrantFiled: July 6, 1993Date of Patent: September 6, 1994Assignee: BASF AktiengesellschaftInventors: Wolfgang Krause, Joachim Paust, Walter Dobler, Hagen Jaedicke
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Patent number: 5276209Abstract: An improved process for the preparation of polyenes by the Julia reaction comprises carrying out the allylation of the anion of an allyl aryl sulfone generated a strong base, and the elimination of arylsulfinic acid to form a double bond in the same inert polar solvent which is immiscible with water, preferably in a ketone of the formula IR.sup.1 --CO--R.sup.2 (I)where R.sup.1 and R.sup.2 are each straight-chain or branched alkyl of 2 to 4 carbons, or R.sup.1 and R.sup.2 together are tetramethylene or pentamethylene. The process is particularly important for the preparation of vitamin A derivatives. In the preparation of vitamin A aldehyde, for example, it is advantageous to use the same alkali metal alcoholate as strong base in both stages so that the conversion can be carried out as one-pot reaction.Type: GrantFiled: July 17, 1992Date of Patent: January 4, 1994Assignee: BASF AktiengesellschaftInventors: Hagen Jaedicke, Klaus Kaiser, Manfred Hamm
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Patent number: 5128151Abstract: Powdered and/or granulated menadione sodium bisulfite formulations additionally contain a physiologically tolerated organic or inorganic acid.The novel formulations possess good water solubility and stability.Type: GrantFiled: January 7, 1988Date of Patent: July 7, 1992Assignee: Basf AktiengesellschaftInventors: Hans Kiefer, Wolfgang Buehler, Joachim U. Schneider, Hagen Jaedicke
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Patent number: 4921711Abstract: An animal feed or drinking water contains a biocidally or biostatically active amount of not less than one formic acid ester of 1,2-propanediol.Type: GrantFiled: November 14, 1986Date of Patent: May 1, 1990Assignee: BASF AktiengesellschaftInventors: Hans Kiefer, Hansjoerg Bipp, Fritz Fink, Hagen Jaedicke, Dieter M. Poralla
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Patent number: 4736040Abstract: 1,2-Benzisothiazolones and their alkali metal salts are prepared by reacting 2,2'-dithiodibenzamides in the presence of oxygen or oxygen donors in an aqueous alkaline medium to which a water-soluble organic solvent may be added and, if desired, freeing the benzisothiazolones from the alkali metal salts with acid.Type: GrantFiled: January 2, 1986Date of Patent: April 5, 1988Assignee: BASF AktiengesellschaftInventors: Peter Tonne, Hagen Jaedicke