Patents by Inventor Haidong Dong

Haidong Dong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DISTINGUISHING ANTAGONISTIC AND AGONISTIC ANTI B7-H1 ANTIBODIES
    Publication number: 20170089918
    Abstract: Materials and methods for distinguishing agonistic anti-B7-H1 antibodies from antagonistic anti-B7-H1 antibodies, and for treating subjects diagnosed with clinical conditions such as cancer, pathogenic infection, or autoimmune disease.
    Type: Application
    Filed: May 21, 2015
    Publication date: March 30, 2017
    Applicant: Mayo Foundation for Medical Education and Research
    Inventor: Haidong Dong
  • METHODS FOR TREATING CANCER IN PATIENTS WITH ELEVATED LEVELS OF BIM
    Publication number: 20160251437
    Abstract: Materials and methods for treating cancer especially in patients identified as having elevated levels of Bim are disclosed. Specifically, the disclosure provides a method for treating a mammal having cancer, the method comprises: (a) identifying said mammal as containing an elevated level of Bim, and (b) administering to said mammal an anti-B7-H1 antibody, an anti-PD-1 antibody, an anti-CD80 antibody, or a fusion protein comprising a portion of PD 1 or a portion of CD80, under conditions wherein the interaction of naturally occurring B7-H1 with PD-1 or CD80 in said mammal is reduced after said administering.
    Type: Application
    Filed: September 3, 2014
    Publication date: September 1, 2016
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Haidong Dong, Susan M. Harrington, Eugene D. Kwon, Christopher J. Krco, Xin Liu
  • METHODS AND MATERIALS FOR TREATING CANCER
    Publication number: 20160176967
    Abstract: This document provides methods and materials involved in treating cancer. For example, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells having the potential to exert anti-cancer effects are provided. In addition, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells and administering a PD-1 inhibitor to such a mammal are provided.
    Type: Application
    Filed: February 26, 2016
    Publication date: June 23, 2016
    Inventors: Haidong Dong, Eugene D. Kwon, Svetomir N. Markovic, Christopher J. Krco
  • B7-H1 AND SURVIVIN IN CANCER
    Publication number: 20160154000
    Abstract: Methods of determining prognosis of a subject with cancer by assessing expression of B7-H1 and survivin in combination.
    Type: Application
    Filed: February 9, 2016
    Publication date: June 2, 2016
    Inventors: Eugene D. Kwon, John C. Cheville, Amy Krambeck, Susan M. Harrington, Robert H. Thompson, Haidong Dong, Christine M. Lohse, Alexander S. Parker
  • B7-H1 AND B7-H4 IN CANCER
    Publication number: 20160153996
    Abstract: Methods of determining prognosis of a subject with cancer or determining risk of cancer progression by assessing expression of B7-H4, or B7-H1 and B7-H4 in combination.
    Type: Application
    Filed: February 9, 2016
    Publication date: June 2, 2016
    Inventors: Eugene D. Kwon, John C. Cheville, Amy Krambeck, Susan M. Harrington, Robert H. Thompson, Lieping Chen, Haidong Dong, Christine M. Lohse
  • Methods and materials for treating cancer
    Patent number: 9302005
    Abstract: This document provides methods and materials involved in treating cancer. For example, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells having the potential to exert anti-cancer effects are provided. In addition, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells and administering a PD-1 inhibitor to such a mammal are provided.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: April 5, 2016
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Haidong Dong, Eugene D. Kwon, Svetomir N. Markovic, Christopher J. Krco
  • Soluble B7-H1
    Publication number: 20150111232
    Abstract: This document features methods of evaluating mammals by assessing expression of B7-H1 in a body fluid.
    Type: Application
    Filed: November 25, 2014
    Publication date: April 23, 2015
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Eugene D. Kwon, Haidong Dong, Xavier Frigola Baro, Brant A. Inman
  • B7-H1 AND B7-H4 IN CANCER
    Publication number: 20140335541
    Abstract: Methods of determining prognosis of a subject with cancer or determining risk of cancer progression by assessing expression of B7-H4, or B7-H1 and B7-H4 in combination.
    Type: Application
    Filed: July 10, 2014
    Publication date: November 13, 2014
    Inventors: Eugene D. Kwon, John C. Cheville, Amy Krambeck, Susan M. Harrington, Robert H. Thompson, Lieping Chen, Haidong Dong, Christine M. Lohse
  • B7-H1 AND SURVIVIN IN CANCER
    Publication number: 20140329248
    Abstract: Methods of determining prognosis of a subject with cancer by assessing expression of B7-H1 and survivin in combination.
    Type: Application
    Filed: July 10, 2014
    Publication date: November 6, 2014
    Inventors: Eugene D. Kwon, John C. Cheville, Amy Krambeck, Susan M. Harrington, Robert H. Thompson, Haidong Dong, Christine M. Lohse, Alexander S. Parker
  • METHODS AND MATERIALS FOR TREATING CANCER
    Publication number: 20140271674
    Abstract: This document provides methods and materials involved in treating cancer. For example, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells having the potential to exert anti-cancer effects are provided. In addition, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells and administering a PD-1 inhibitor to such a mammal are provided.
    Type: Application
    Filed: February 27, 2014
    Publication date: September 18, 2014
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Haidong Dong, Eugene D. Kwon, Svetomir N. Markovic, Christopher J. Krco
  • B7-H1 AND SURVIVIN IN CANCER
    Publication number: 20100015642
    Abstract: Methods of determining prognosis of a subject with cancer by assessing expression of B7-H1 and survivin in combination.
    Type: Application
    Filed: January 5, 2007
    Publication date: January 21, 2010
    Inventors: Eugene D. Kwon, John C. Cheville, Amy Krambeck, Susan Kuntz, Robert H. Thompson, Haidong Dong, Christine M. Lohse, Alexander S. Parker
  • B7-H1 AND B7-H4 IN CANCER
    Publication number: 20090215084
    Abstract: Methods of determining prognosis of a subject with cancer or determining risk of cancer progression by assessing expression of B7-H4, or B7-H1 and B7-H4 in combination.
    Type: Application
    Filed: January 5, 2007
    Publication date: August 27, 2009
    Inventors: Eugene D. Kwon, John C. Cheville, Amy Krambeck, Susan Kuntz, Robert H. Thompson, Lieping Chen, Haidong Dong, Christine M. Lohse
  • Soluble B7-H1
    Publication number: 20090176317
    Abstract: This document features methods of evaluating mammals by assessing expression of B7-H4 in the vasculature.
    Type: Application
    Filed: October 20, 2008
    Publication date: July 9, 2009
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Eugene D. Kwon, Haidong Dong, Xavier Frigola Baro, Brant A. Inman