Patents by Inventor Hailiang Chen

Hailiang Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240133175
    Abstract: A top-down construction method for a multi-storey basement with a full steel structure is provided, including: S1, constructing a diaphragm wall permanent structure; S2. conducting an open excavation, then constructing a first layer structural beam and slab; S3. conducting an underground excavation on an underground second layer earthwork, then constructing structural beam and slab and vertical shear wall on underground first layer; S4. excavating earthworks from an underground third layer to an underground N?1 layer, and constructing structural beams and slabs and vertical shear walls; S5. conducting the underground excavation on an underground N layer earthwork, and constructing a two-span structural steel beam; S6. conducting the underground excavation on earthworks of bottom plate layer, constructing remaining structural beams and slabs and vertical shear wall; S7. conducting the underground excavation on earthworks of bearing platform and water collection well; S8.
    Type: Application
    Filed: October 17, 2023
    Publication date: April 25, 2024
    Inventors: Xiuyi Wang, Xiaolu Deng, Caihui Wu, Bin Chen, Hailiang Peng, Weimin Wen
  • Patent number: 11386164
    Abstract: A computer implemented method for searching electronic documents, and associated system and computer program product. The method includes receiving an input representing an example-based search query and processing the input. The method also includes determining, for each of the electronic documents, a relevance score between the input and the corresponding electronic document. The determination is based on, at least, textual similarity between the input and the corresponding electronic document, topical similarity between the input and the corresponding electronic document, as well as linkage relationship in a linkage network of the plurality of electronic documents. The method also includes determining, based on the determined relevance scores, a search result containing one or more of the electronic documents. The search results will be provided to the user.
    Type: Grant
    Filed: May 13, 2020
    Date of Patent: July 12, 2022
    Assignees: City University of Hong Kong, The University of Hong Kong
    Inventors: Jianliang Zhao, Hailiang Chen, Ruiyun Xu
  • Publication number: 20210357455
    Abstract: A computer implemented method for searching electronic documents, and associated system and computer program product. The method includes receiving an input representing an example-based search query and processing the input. The method also includes determining, for each of the electronic documents, a relevance score between the input and the corresponding electronic document. The determination is based on, at least, textual similarity between the input and the corresponding electronic document, topical similarity between the input and the corresponding electronic document, as well as linkage relationship in a linkage network of the plurality of electronic documents. The method also includes determining, based on the determined relevance scores, a search result containing one or more of the electronic documents. The search results will be provided to the user.
    Type: Application
    Filed: May 13, 2020
    Publication date: November 18, 2021
    Inventors: Jianliang Zhao, Hailiang Chen, Ruiyun Xu
  • Patent number: 11136030
    Abstract: The present disclosure provides a method and a device for controlling a vehicle. The vehicle is in a vehicle queue, the vehicle queue includes n vehicles {vehicle 0, vehicle 1, . . . , vehicle n?1} arranged in order along a traveling direction, the method is performed by a computing device of the vehicle i, i is from 1 to n?1. A vehicle-following subsystem model is established based on the relative speed and the relative vehicle distance error between the vehicle i and a vehicle i?1, and the acceleration of the vehicle i, a state trajectory of the vehicle-following subsystem model on a ?v-?R plane is determined, a plurality of division graphs of the vehicle i?1 in a plurality of travelling phases are combined to obtain a switching control graph for the vehicle i, and the travelling phase of the vehicle i is adjusted.
    Type: Grant
    Filed: January 19, 2020
    Date of Patent: October 5, 2021
    Assignee: TSINGHUA UNIVERSITY
    Inventors: Shengbo Li, Bo Cheng, Keqiang Li, Hongbo Gao, Xiaoxue Zhang, Renjie Li, Zhitao Wang, Hailiang Chen, Jianqiang Wang, Yugong Luo, Diange Yang
  • Patent number: 10941150
    Abstract: Disclosed in the present invention are a salt type and crystal type of 4H-pyrazolo[1, 5-alpha]benzimidazole compound and the preparation method and intermediate thereof. The 4H-pyrazolo[1,5-alpha]benzimidazole compound has the structure of Compound 2.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: March 9, 2021
    Assignees: HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE INC., HUMANWELL HEALTHCARE (GROUP) CO., LTD.
    Inventors: Xuehai Wang, Charles Z. Ding, Jie Shen, Shuhui Chen, Lie Li, Gang Li, Yong Xu, Cailin Wang, Ronghua Tu, Jimeng Wang, Yang YuE, Biao Deng, Hailiang Chen, Hui Liu, Wenjie Sun, Cong Wang, Lu Huang, Zheng Wang, Weidong Li
  • Patent number: 10888616
    Abstract: This invention relates to ready-to-use and safe solution compositions of glucagon suitable for administration by manual injection or by an insulin pump or other injection device to treat hypoglycemia. Said compositions comprise glucagon, an acid, anti-gelling polyol, a stabilizing-salt, viscosity reducer and an antioxidant, have a final pH between about 2 and 5, and is gel-free, chemically-stable, and pump-able.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: January 12, 2021
    Assignee: LATITUDE PHARMACEUTICALS, INC.
    Inventors: Hailiang Chen, Andrew Xian Chen, Norman Keith Orida
  • Publication number: 20200339159
    Abstract: An automatic driving track obtaining method and apparatus are provided. The method includes: obtaining a driving style coefficient of a driver of a vehicle A (S101); calculating a cost function of the driver of the vehicle A based on the driving style coefficient of the driver of the vehicle A (S102), where the cost function is used to represent costs paid when the vehicle A travels from an initial node to a current node in a driving track of the vehicle A; and obtaining the driving track of the vehicle A on a first three-dimensional spatial-temporal map through calculation according to the cost function (S103). The driving track obtained by using the method and the apparatus can match driving styles of all drivers. This improves driver satisfaction on the driving track, and lessens a running-in period in which the driver performs automatic driving.
    Type: Application
    Filed: July 9, 2020
    Publication date: October 29, 2020
    Inventors: Haiyan ZHONG, Shengbo LI, Jieyun DING, Bo CHENG, Long XIN, Yang GUAN, Hailiang CHEN
  • Patent number: 10747759
    Abstract: A system and a method for conducting a textual data search includes receiving a search query associated with a search topic; analyzing the search query to determine at least one attribute of the search topic; processing the at least one attribute and a plurality of articles in a database; and identifying one or more results being relevant to the search topic in the plurality of articles in the database.
    Type: Grant
    Filed: June 23, 2017
    Date of Patent: August 18, 2020
    Assignee: City University of Hong Kong
    Inventors: Ruiyun Xu, Hailiang Chen, J. Leon Zhao
  • Publication number: 20200180624
    Abstract: The present disclosure provides a method and a device for controlling a vehicle. The vehicle is in a vehicle queue, the vehicle queue includes n vehicles {vehicle 0, vehicle 1, . . . , vehicle n?1} arranged in order along a traveling direction, the method is performed by a computing device of the vehicle i, i is from 1 to n?1. A vehicle-following subsystem model is established based on the relative speed and the relative vehicle distance error between the vehicle i and a vehicle i?1, and the acceleration of the vehicle i, a state trajectory of the vehicle-following subsystem model on a ?v-?R plane is determined, a plurality of division graphs of the vehicle i?1 in a plurality of travelling phases are combined to obtain a switching control graph for the vehicle i, and the travelling phase of the vehicle i is adjusted.
    Type: Application
    Filed: January 19, 2020
    Publication date: June 11, 2020
    Inventors: Shengbo LI, Bo CHENG, Keqiang LI, Hongbo GAO, Xiaoxue ZHANG, Renjie LI, Zhitao WANG, Hailiang CHEN, Jianqiang WANG, Yugong LUO, Diange YANG
  • Patent number: 10662174
    Abstract: Provided are a series of BTK inhibitors, and specifically disclosed are a compound, pharmaceutically acceptable salt thereof, tautomer thereof or prodrug thereof represented by formula (I), (II), (III) or (IV).
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: May 26, 2020
    Assignee: HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC.
    Inventors: Xuehai Wang, Chengde Wu, Yong Xu, Chunli Shen, Li'e Li, Guoping Hu, Yang Yue, Jian Li, Diliang Guo, Nengyang Shi, Lu Huang, Shuhui Chen, Ronghua Tu, Zhongwen Yang, Xuwen Zhang, Qiang Xiao, Hua Tian, Yanping Yu, Hailiang Chen, Wenjie Sun, Zhenyu He, Jie Shen, Jing Yang, Jing Tang, Wen Zhou, Jing Yu, Yi Zhang, Quan Liu
  • Publication number: 20190375756
    Abstract: Disclosed in the present invention are a salt type and crystal type of 4H-pyrazolo[1, 5-alpha]benzimidazole compound and the preparation method and intermediate thereof.
    Type: Application
    Filed: August 22, 2019
    Publication date: December 12, 2019
    Inventors: Xuehai WANG, Charles Z. DING, Jie SHEN, Shuhui CHEN, Lie LI, Gang LI, Yong XU, Cailin WANG, Ronghua TU, Jimeng WANG, Yang YUE, Biao DENG, Hailiang CHEN, Hui LIU, Wenjie SUN, Cong WANG, Lu HUANG, Zheng WANG, Weidong LI
  • Patent number: 10428073
    Abstract: Disclosed in the present invention are a salt type and crystal type of 4H-pyrazolo[1,5-alpha]benzimidazole compound and a preparation method and intermediate thereof.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: October 1, 2019
    Assignees: Hubei Bio-Pharmaceutical Industrial Technological Institute Inc., Humanwell Healthcare (Group) Co., Ltd.
    Inventors: Xuehai Wang, Charles Z. Ding, Jie Shen, Shuhui Chen, Lie Li, Gang Li, Yong Xu, Cailin Wang, Ronghua Tu, Jimeng Wang, Yang Yue, Biao Deng, Hailiang Chen, Hui Liu, Wenjie Sun, Cong Wang, Lu Huang, Zheng Wang, Weidong Li
  • Patent number: 10369101
    Abstract: The present application provides parenteral compositions of diclofenac or its pharmaceutically acceptable salt and methods for making and using such compositions. Some of the compositions of the present application has one or more following properties: (1) ready to be injectable, (2) in the form of an oil-in-water emulsion, (3) stable under appropriate storage conditions, (4) containing therapeutically effective amount of diclofenac or its pharmaceutically acceptable salt, (5) sterilizable by filtration (6) containing components acceptable by regulatory agencies (e.g. the FDA), (7) containing low oil content and thus not exacerbating hyerlipidemia, and (8) is neither hyperallergenic nor vein irritating.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: August 6, 2019
    Assignee: LATITUDE PHARMACEUTICALS INC.
    Inventors: Franklin Okumu, Andrew X. Chen, Hailiang Chen
  • Publication number: 20180373754
    Abstract: A system and a method for conducting a textual data search includes receiving a search query associated with a search topic; analyzing the search query to determine at least one attribute of the search topic; processing the at least one attribute and a plurality of articles in a database; and identifying one or more results being relevant to the search topic in the plurality of articles in the database.
    Type: Application
    Filed: June 23, 2017
    Publication date: December 27, 2018
    Inventors: RUIYUN XU, HAILIANG CHEN, J. LEON ZHAO
  • Publication number: 20180258093
    Abstract: Disclosed in the present invention are a salt type and crystal type of 4H-pyrazolo[1, 5-alpha]benzimidazole compound and the preparation method and intermediate thereof.
    Type: Application
    Filed: September 29, 2016
    Publication date: September 13, 2018
    Inventors: Xuehai WANG, Charles Z. DING, Jie SHEN, Shuhui CHEN, Lie LI, Gang LI, Yong XU, Cailin WANG, Ronghua TU, Jimeng WANG, Yang YUE, Biao DENG, Hailiang CHEN, Hui LIU, Wenjie SUN, Cong WANG, Lu HUANG, Zheng WANG, Weidong LI
  • Publication number: 20180236079
    Abstract: This invention relates to ready-to-use and safe solution compositions of glucagon suitable for administration by manual injection or by an insulin pump or other injection device to treat hypoglycemia. Said compositions comprise glucagon, an acid, anti-gelling polyol, a stabilizing-salt, viscosity reducer and an antioxidant, have a final pH between about 2 and 5, and is gel-free, chemically-stable, and pump-able.
    Type: Application
    Filed: February 22, 2018
    Publication date: August 23, 2018
    Applicant: Latitude Pharmaceuticals, Inc.
    Inventors: Hailiang CHEN, Andrew Xian CHEN, Norman Keith ORIDA
  • Patent number: 9856262
    Abstract: Disclosed is a series of analogs of 4H-pyrazolo[1,5-?]benzimidazole compound as PARP inhibitors. In particular, disclosed in the invention is a compound as shown by formula (I) or a pharmaceutically acceptable salt thereof as a PARP inhibitor.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: January 2, 2018
    Assignees: Hubei Bio-Pharmaceutical Industrial Technological Institute Inc., Humanwell Healthcare (Group) Co., Ltd., Medshine Discovery Inc.
    Inventors: Xuehai Wang, Zhaozhong Ding, Yong Xu, Shuhui Chen, Lie Li, Gang Li, Ronghua Tu, Cailin Wang, Yang Yue, Zhibo Zhang, Hailiang Chen, Wenjie Sun, Lu Huang
  • Publication number: 20170313683
    Abstract: Provided are a series of BTK inhibitors, and specifically disclosed are a compound, pharmaceutically acceptable salt thereof, tautomer thereof or prodrug thereof represented by formula (I), (II), (III) or (IV).
    Type: Application
    Filed: July 14, 2017
    Publication date: November 2, 2017
    Inventors: Xuehai Wang, Chengde Wu, Yong Xu, Chunli Shen, Li'e Li, Guoping Hu, Yang Yue, Jian Li, Diliang Guo, Nengyang Shi, Lu Huang, Shuhui Chen, Ronghua Tu, Zhongwen Yang, Xuwen Zhang, Qiang Xiao, Hua Tian, Yanping Yu, Hailiang Chen, Wenjie Sun, Zhenyu He, Jie Shen, Jing Yang, Jing Tang, Wen Zhou, Jing Yu, Yi Zhang, Quan Liu
  • Publication number: 20170246109
    Abstract: The present invention provides a clear depot comprising at least one hydrophilic water-soluble pharmaceutically active agent selected from the group consisting of vancomycin, gentamicin, a pharmaceutically acceptable salt thereof and a mixture thereof, water, a phospholipid, an oil, optionally a pH adjusting agent, and a viscosity modifying agent selected from the group consisting of ethanol, isopropanol, and a mixture thereof, wherein the water present in the depot is no more than about 4 wt % relative to the total weight of the depot and the depot has a pH of between about 3 and about 6, method of making and administering same.
    Type: Application
    Filed: May 15, 2017
    Publication date: August 31, 2017
    Inventors: Hailiang CHEN, Andrew Xian CHEN, Dushyanth SURAKANTI, Franklin OKUMU
  • Publication number: 20170189532
    Abstract: The present invention is directed to compositions and methods of preparation of phospholipid depots that are injectable through a fine needle.
    Type: Application
    Filed: October 28, 2016
    Publication date: July 6, 2017
    Applicant: Latitude Pharmaceuticals Inc.
    Inventors: Andrew Xian Chen, Hailiang Chen