Patents by Inventor Hailing Jin

Hailing Jin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240306649
    Abstract: The disclosure provides stable antimicrobial (e.g., antibacterial or antifungal or both) peptides (SAMPs) that may be used in methods of preventing or treating a bacterial disease (e.g., a Liberibacter disease, such as citrus greening disease (also called Huanglongbing (HLB)) or potato Zebra Chip disease, and other bacterial diseases such as those caused by Agrobacterium tumefaciens (also known as Rhizobium radiobacter) and Pseudomonas syringae) in plants (e.g., citrus plants or potato plants). SAMPs disclosed herein may be heat stable, as well as stable in plant extracts and/or in plant lysates (e.g., citrus lysates).
    Type: Application
    Filed: March 19, 2024
    Publication date: September 19, 2024
    Inventors: Hailing JIN, Chien Yu Huang
  • Publication number: 20240268396
    Abstract: Compositions comprising an antifungal RNA and a lipid vesicle are provided, wherein the antifungal RNA comprises a double-stranded RNA, a small RNA, or a small RNA duplex. The lipid vesicle may be, for example, a plant-derived vesicle or an artificial vesicle containing a tertiary amine cationic lipid. For example, the RNA may target a dicer-like (DCL) gene or a long terminal repeat (LTR) region of a fungal pathogen such as Botrytis or Verticillium. Methods for increasing pathogen resistance in plants are also described.
    Type: Application
    Filed: June 16, 2022
    Publication date: August 15, 2024
    Inventor: Hailing Jin
  • Patent number: 11963533
    Abstract: The disclosure provides stable antimicrobial (e.g., antibacterial or antifungal or both) peptides (SAMPs) that may be used in methods of preventing or treating a bacterial disease (e.g., a Liberibacter disease, such as citrus greening disease (also called Huanglongbing (HLB)) or potato Zebra Chip disease, and other bacterial diseases such as those caused by Agrobacterium tumefaciens (also known as Rhizobium radiobacter) and Pseudomonas syringae) in plants (e.g., citrus plants or potato plants). SAMPs disclosed herein may be heat stable, as well as stable in plant extracts and/or in plant lysates (e.g., citrus lysates).
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: April 23, 2024
    Assignee: The Regents of The University of California
    Inventors: Hailing Jin, Chien Yu Huang
  • Publication number: 20240124887
    Abstract: The present disclosure provides methods and compositions for increasing resistance of plants to a disease caused by infection with bacteria of a Liberibacter species.
    Type: Application
    Filed: February 9, 2022
    Publication date: April 18, 2024
    Applicant: The Regents of the University of California
    Inventors: Hailing Jin, Chien Yu Huang
  • Publication number: 20240109941
    Abstract: The disclosure provides stable antimicrobial (e.g., antibacterial or antifungal or both) peptides (SAMPs) that can be used in methods of preventing or treating a bacterial disease (e.g., a Liberibacter disease, such as citrus greening disease (also called Huanglongbing (HLB)) or potato Zebra Chip disease, and other bacterial diseases such as those caused by Agrobacterium tumefaciens (also known as Rhizobium radiobacter) and Pseudomonas syringae) in plants (e.g., citrus plants or potato plants).
    Type: Application
    Filed: October 10, 2020
    Publication date: April 4, 2024
    Inventors: Hailing Jin, Chien Yu Huang
  • Publication number: 20240084302
    Abstract: The disclosure provides RNAi strategies for targeting a fungal tetraspanin protein.
    Type: Application
    Filed: August 7, 2023
    Publication date: March 14, 2024
    Inventor: Hailing Jin
  • Patent number: 11746355
    Abstract: The present invention relates to pathogen-resistant plants. In one aspect, plants comprising a heterologous expression cassette are provided, wherein the expression cassette comprises a polynucleotide that inhibits expression of a fungal pathogen gene and wherein the plant has increased resistance to a fungal pathogen or multiple pathogens compared to a control plant lacking the expression cassette. In another aspect, contacting a plant or a plant part with double stranded RNAs or small RNAs that inhibit expression of a fungal target gene or genes from multiple pathogens, wherein the plant has increased resistance to a pathogen or multiple pathogens compared to control plants that has not been contacted with the RNAs. Methods of making and cultivating pathogen-resistant plants are also provided.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: September 5, 2023
    Assignee: The Regents of The University of California
    Inventor: Hailing Jin
  • Patent number: 11085051
    Abstract: The present invention relates to methods of increasing pathogen resistance in a plant or a part of a plant. In one aspect, the method comprises contacting the plant or the part of the plant with a double-stranded RNA or a small RNA duplex that targets a fungal dicer-like (DCL) gene, wherein the plant or the part of the plant has increased resistance to a fungal pathogen compared to a control plant or control plant part that has not been contacted with the double-stranded RNA or small RNA duplex.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: August 10, 2021
    Assignee: The Regents of the University of California
    Inventor: Hailing Jin
  • Publication number: 20210186028
    Abstract: The disclosure provides stable antimicrobial (e.g., antibacterial or antifungal or both) peptides (SAMPs) that may be used in methods of preventing or treating a bacterial disease (e.g., a Liberibacter disease, such as citrus greening disease (also called Huanglongbing (HLB)) or potato Zebra Chip disease, and other bacterial diseases such as those caused by Agrobacterium tumefaciens (also known as Rhizobium radiobacter) and Pseudomonas syringae) in plants (e.g., citrus plants or potato plants). SAMPs disclosed herein may be heat stable, as well as stable in plant extracts and/or in plant lysates (e.g., citrus lysates).
    Type: Application
    Filed: October 23, 2018
    Publication date: June 24, 2021
    Inventors: Hailing JIN, Chien Yu HUANG
  • Patent number: 11015207
    Abstract: Provided are pathogen-resistant plants comprising a heterologous expression cassette, the expression cassette comprising a promoter operably linked to a polynucleotide that is complementary to, or mediates destruction, of a plant immunity suppressing sRNA of a pathogen, wherein the plant is less susceptible to the pathogen compared to a control plant lacking the expression cassette. Methods of making and cultivating pathogen-resistant plants are also provided.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: May 25, 2021
    Assignee: The Regents of the University of California
    Inventor: Hailing Jin
  • Patent number: 10962820
    Abstract: The embodiments of the present disclosure provide a display substrate and a display device, which relate to the field of display technologies, to solve the problem that a saw-toothed display effect occurs at an edge of an AA area when displaying if the edge of the AA area is non-linear. The display substrate includes a black matrix. The display substrate is provided with a display area, and at least a part of an edge of the display area has an irregular edge having a concave-convex shape. The display area has a plurality of subpixels arranged in a matrix form, and has a vision weakening area close to the irregular edge. In the vision weakening area, the black matrix includes a light shielding block located in the subpixel.
    Type: Grant
    Filed: July 19, 2018
    Date of Patent: March 30, 2021
    Assignees: BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Dawei Wang, Jiaqiang Wang, Rui Liu, Jian Ren, Jingfei Mu, Yanchao Zhang, Yanming Wang, Hailing Jin, Xiujun Cai
  • Publication number: 20210062247
    Abstract: The present invention provides compositions and methods for detecting Candidatus liberibacter infection and Huanglongbing disease in a citrus plant by detecting the expression of small RNAs such as miRNA and siRNA. The invention also provides methods for treating Huanglongbing disease in a citrus plant by contacting the plant with a phosphorus containing solution.
    Type: Application
    Filed: November 2, 2020
    Publication date: March 4, 2021
    Inventor: Hailing JIN
  • Publication number: 20200340003
    Abstract: The present invention relates to pathogen-resistant plants. In one aspect, plants comprising a heterologous expression cassette are provided, wherein the expression cassette comprises a polynucleotide that inhibits expression of a fungal pathogen gene and wherein the plant has increased resistance to a fungal pathogen or multiple pathogens compared to a control plant lacking the expression cassette. In another aspect, contacting a plant or a plant part with double stranded RNAs or small RNAs that inhibit expression of a fungal target gene or genes from multiple pathogens, wherein the plant has increased resistance to a pathogen or multiple pathogens compared to control plants that has not been contacted with the RNAs. Methods of making and cultivating pathogen-resistant plants are also provided.
    Type: Application
    Filed: October 4, 2018
    Publication date: October 29, 2020
    Inventor: Hailing Jin
  • Patent number: 10724049
    Abstract: The present invention relates to pathogen-resistant plants. In one aspect, plants comprising a heterologous expression cassette are provided, wherein the expression cassette comprises a polynucleotide that inhibits expression of a fungal pathogen dicer-like (DCL) gene and wherein the plant has increased resistance to a fungal pathogen compared to a control plant lacking the expression cassette. Methods of making and cultivating pathogen-resistant plants are also provided.
    Type: Grant
    Filed: July 24, 2015
    Date of Patent: July 28, 2020
    Assignee: The Regents of the University of California
    Inventor: Hailing Jin
  • Publication number: 20190235307
    Abstract: The embodiments of the present disclosure provide a display substrate and a display device, which relate to the field of display technologies, to solve the problem that a saw-toothed display effect occurs at an edge of an AA area when displaying if the edge of the AA area is non-linear. The display substrate includes a black matrix. The display substrate is provided with a display area, and at least a part of an edge of the display area has an irregular edge having a concave-convex shape. The display area has a plurality of subpixels arranged in a matrix form, and has a vision weakening area close to the irregular edge. In the vision weakening area, the black matrix includes a light shielding block located in the subpixel.
    Type: Application
    Filed: July 19, 2018
    Publication date: August 1, 2019
    Inventors: Dawei WANG, Jiaqiang WANG, Rui LIU, Jian REN, Jingfei MU, Yanchao ZHANG, Yanming WANG, Hailing JIN, Xiujun CAI
  • Publication number: 20190078116
    Abstract: Provided are pathogen-resistant plants comprising a heterologous expression cassette, the expression cassette comprising a promoter operably linked to a polynucleotide that is complementary to, or mediates destruction, of a plant immunity suppressing sRNA of a pathogen, wherein the plant is less susceptible to the pathogen compared to a control plant lacking the expression cassette. Methods of making and cultivating pathogen-resistant plants are also provided.
    Type: Application
    Filed: September 24, 2018
    Publication date: March 14, 2019
    Inventor: Hailing Jin
  • Patent number: 10119148
    Abstract: The present invention relates to pathogen-resistant plants comprising a heterologous expression cassette, the expression cassette comprising a promoter operably linked to a polynucleotide that is complementary to, or mediates destruction, of a plant immunity suppressing sRNA of a pathogen, wherein the plant is less susceptible to the pathogen compared to a control plant lacking the expression cassette. Methods of making and cultivating pathogen-resistant plants are also provided.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: November 6, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventor: Hailing Jin
  • Publication number: 20180142253
    Abstract: The present invention relates to methods of increasing pathogen resistance in a plant or a part of a plant. In one aspect, the method comprises contacting the plant or the part of the plant with a double-stranded RNA or a small RNA duplex that targets a fungal dicer-like (DCL) gene, wherein the plant or the part of the plant has increased resistance to a fungal pathogen compared to a control plant or control plant part that has not been contacted with the double-stranded RNA or small RNA duplex.
    Type: Application
    Filed: April 27, 2016
    Publication date: May 24, 2018
    Inventor: Hailing JIN
  • Publication number: 20180066308
    Abstract: The present invention provides compositions and methods for detecting Candidatus Liberibacter infection and Huanglongbing disease in a citrus plant by detecting the expression of small RNAs such as miRNA and siRNA. The invention also provides methods for treating Huanglongbing disease in a citrus plant by contacting the plant with a phosphorus containing solution.
    Type: Application
    Filed: August 4, 2017
    Publication date: March 8, 2018
    Inventor: Hailing JIN
  • Patent number: 9758836
    Abstract: The present invention provides compositions and methods for detecting Candidatus Liberibacter infection and Huanglongbing disease in a citrus plant by detecting the expression of small RNAs such as miRNA and siRNA. The invention also provides methods for treating Huanglongbing disease in a citrus plant by contacting the plant with a phosphorus containing solution.
    Type: Grant
    Filed: March 7, 2012
    Date of Patent: September 12, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventor: Hailing Jin