Abstract: A recombinant fusion protein comprising a human erythropoietin peptide portion linked to an immunoglobulin peptide portion is described. The fusion protein has a prolonged half-life in vivo in comparison to naturally occurring or recombinant native human erythropoietin. In one embodiment of the invention, the protein has a half-life in vivo at least three fold higher than native human erythropoietin. The fusion protein also exhibits enhanced erythropoietic bioactivity in comparison to native human erythropoietin. In one embodiment, the fusion protein comprises the complete peptide sequence of a human erythropoietin (EPO) molecule and the peptide sequence of an Fc fragment of human immunoglobulin IgG1. The Fc fragment in the fusion protein includes the hinge region, CH2 and CH3 domains of human immunoglobulin IgG1. The EPO molecule may be linked directly to the Fc fragment to avoid extraneous peptide linkers and lessen the risk of an immunogenic response when administered in vivo.

Abstract: A recombinant fusion protein comprising a human erythropoietin peptide portion linked to an immunoglobulin peptide portion is described. The fusion protein has a prolonged half-life in vivo in comparison to naturally occurring or recombinant native human erythropoietin. In one embodiment of the invention, the protein has a half-life in vivo at least three fold higher than native human erythropoietin. The fusion protein also exhibits enhanced erythropoietic bioactivity in comparison to native human erythropoietin. In one embodiment, the fusion protein comprises the complete peptide sequence of a human erythropoietin (EPO) molecule and the peptide sequence of an Fc fragment of human immunoglobulin IgG1. The Fc fragment in the fusion protein includes the hinge region, CH2 and CH3 domains of human immunoglobulin IgG1. The EPO molecule may be linked directly to the Fc fragment to avoid extraneous peptide linkers and lessen the risk of an immunogenic response when administered in vivo.

Abstract: This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human interferon alpha 2b (HuIFN-?2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID No: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon therapy, such as viral diseases and cancer.

Abstract: A computer implemented bidding method for use in bidding on auction items that allows for a desired optimization of bid amounts. The method includes selecting a set of one or more biddable items offered at auction wherein for a biddable item the auction offers a ranking for one or more received bids according to bid amounts, determining the current bids for a set of the biddable items, determining a bid amount for a selected biddable item based on a given utility function to determine a set of rankings for achieving a desired optimized outcome from the bidding, and submitting a set of bid amounts.

Abstract: Solar component and devices containing the same are disclosed. The solar component includes coupling an upper member, a lower member, and at least two side members to form a cavity for housing a plurality of solar cells. Adjacent solar cells may have unused spaces thereby allowing apertures to be formed therethrough the upper member and the lower member. The apertures are capable of allowing air flow through the cavity thereby leading to reduced wind resistance of the solar component.

Abstract: Solar-powered device having a body for housing at least one energy storage module and at least one control module are disclosed. The body includes an opening formed by at least two recesses disposed about an upper surface of the body. At least one solar panel may be coupled to the upper surface of the body where the solar panel may be received by the recesses.

Abstract: A recombinant fusion protein comprising a human erythropoietin peptide portion linked to an immunoglobulin peptide portion is described. The fusion protein has a prolonged half-life in vivo in comparison to naturally occurring or recombinant native human erythropoietin. In one embodiment of the invention the protein has a half-life in vivo at least three fold higher than native human erythropoietin. The fusion protein also exhibits enhanced erythropoietic bioactivity in comparison to native human erythropoietin. In one embodiment, the fusion protein comprises the complete peptide sequence of a human erythropoietin (EPO) molecule and the peptide sequence of an Fc fragment of human immunoglobulin IgG1. The Fc fragment in the fusion protein includes the hinge region, CH2 and CH3 domains of human immunoglobulin IgG1. The EPO molecule may be linked directly to the Fc fragment to avoid extraneous peptide linkers and lessen the risk of an immunogenic response when administered in vivo.

Abstract: This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human interferon alpha 2b (HuIFN-?2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID No: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon therapy, such as viral diseases and cancer.

Abstract: A recombinant fusion protein comprising a human erythropoietin peptide portion linked to an immunoglobulin peptide portion is described. The fusion protein has a prolonged half-life in vivo in comparison to naturally occurring or recombinant native human erythropoietin. In one embodiment of the invention, the protein has a half-life in vivo at least three fold higher than native human erythropoietin. The fusion protein also exhibits enhanced erythropoietic bioactivity in comparison to native human erythropoietin. In one embodiment, the fusion protein comprises the complete peptide sequence of a human erythropoietin (EPO) molecule and the peptide sequence of an Fc fragment of human immunoglobulin IgG1. The Fc fragment in the fusion protein includes the hinge region, CH2 and CH3 domains of human immunoglobulin IgG1. The EPO molecule may be linked directly to the Fc fragment to avoid extraneous peptide linkers and lessen the risk of an immunogenic response when administered in vivo.

Abstract: A image verification method, medium, and apparatus using a local binary pattern (LBP) discriminant technique. The verification method includes generating a kernel fisher discriminant analysis (KFDA) basis vector by using the LBP feature of an input image, obtaining a Chi square inner product by using the LBP feature of an image registered in advance and a kernel LBP feature and projecting to a KFDA basis vector, obtaining a Chi square inner product by using the LBP feature of a query image and a kernel LBP feature and projecting to a KFDA basis vector, and obtaining the similarity degree of the target image and the query image that are obtained as Chi square inner product results, and projected to the KFDA basis vector. According to the method, medium, and apparatus, the KFDA based LBP shows superior performance over conventional LBP, KFDA, and biometric experimentation environment (BEE) baseline algorithms.

Abstract: A fusion protein having a non-immunoglobulin polypeptide having a cysteine residue proximal to the C terminal thereof, and an immunoglobulin component with a mutated hinge region is provided. The mutation comprises a point mutated site corresponding in position to the position in a native hinge region of the cysteine residue located nearest the cysteine residue of the non-Ig component. The distance from the cysteine residue of the non-immunoglobulin polypeptide and any remaining cysteine residues of the mutated hinge region is sufficient to prevent the formation of a disulphide bond therebetween.

Abstract: This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human interferon alpha 2b (HuIFN-?2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID No: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon therapy, such as viral diseases and cancer.

Abstract: An object pose normalization method and apparatus and an object recognition method are provided. The object pose normalization method includes: determining a pose of a non-frontal image of an object; performing smoothing transformation on the non-frontal image of the object, thereby generating a smoothed object image; and synthesizing a frontal image of the object by using the pose determination result and the smoothed object image. According to the method and apparatus, a front object image can be synthesized by using a non-frontal object image without causing an image distortion problem due to self-occlusion and non-rigid deformation.

Abstract: Object feature points are tracked in a video image, and detected feature points are affine-transformed. Then, it is determined whether the video image is a real object using characteristics of the affine-transformed feature points. Therefore, liveness detection resistant to spoofing can be performed without requiring user intervention and additional hardware.

Abstract: A method and apparatus for tracking an object, and a method and apparatus for calculating object pose information are provided. The method of tracking the object obtains object feature point candidates by using a difference between pixel values of neighboring frames. A template matching process is performed in a predetermined region having the object feature point candidates as the center. Accordingly, it is possible to reduce a processing time needed for the template matching process. The method of tracking the object is robust in terms of sudden changes in lighting and partial occlusion. In addition, it is possible to track the object in real time. In addition, since the pose of the object, the pattern of the object, and the occlusion of the object are determined, detailed information on action patterns of the object can be obtained in real time.

Abstract: Open loop transmit power calculations made by a wireless communication receiving device use only the portion of the received signal power that is due to the transmitting device serving the wireless device, rather than using the total received power from all transmitting devices. In one embodiment a discernable signal trait of, such as a preamble, is used to identify signal power from a serving transmitter. In some embodiments, open loop power control may also used to transmit power limits established from closed loop power control sessions, in order to minimize power fluctuations. Digitally scaling data values compensates for transmitter power level settings by adjusting data values prior to modulation such that the modulated waveform contains a different power level than the original data values would provide.

Abstract: The pilots of a wireless system are arranged to reduce inter-sector interference by establishing a systematic assignment of pilots across the system. In one embodiment, the pilots are differently coded and directionally positioned within a cell such that the same pilot from adjacent cells do not overlap. In one embodiment, Walsh codes are used to create the differently coded pilot signals.

Abstract: Offsets in the transmit clock in a wireless communication system are corrected by using data distributed over many frequencies. In the time domain the system uses separate copies of the same signal transmitted with a known spacing in terms of transmit clock signals. The variation of timing between the received signals yields an initial estimate that then is used in a closed loop tracking arrangement to yield and compensate for unpredictable rate changes caused by, for example, jitter, Doppler or thermal drift. The frequency offset for one channel can then be used to calculate the offset for other channels.

Abstract: A system and method are provided for automatic gain control (AGC) using an adaptive reference and a threshold. An adaptive reference allows for adjusting the target power based on variations in operating parameters and conditions, such as a change to a modulation schemes which requires a different signal to noise ratio (SNR) to maintain performance. A gain adjustment threshold allows for rapid AGC response while reducing the potential effects of hysteresis. AGC levels may be changed during symbol prefixes or suffixes, and avoided during a data portion of a signal. Embodiments allow for symbol-by symbol AGC changes in OFDM, OFDMA, and TDD systems.

Abstract: A face detection method where a cascaded weak classifier and a result of a previous stage are combined. The weak classifier is based on a modified double sigmoid function to precisely and effectively estimate each Haar feature. The face detection method includes a method of training a parameter of a new weak classifier.