Abstract: The present invention provides a mobile communication system sub-network comprising a macrocell base station, and a plurality of small cell base stations, the plurality of small cell base stations being in wireless communication with the macrocell base station, wherein each small cell base station is either in direct connection with the macrocell base station or is in connection with the macrocell base station via one or more other small cell base stations, wherein the macrocell base station is arranged to configure a UE device having a RRC connection to the macrocell base station with candidate small cell base station information for enabling the UE device to switch autonomously between small cell base stations, and wherein the macrocell base station is arranged to configure the small cell base stations with small cell base station configuration information.

Abstract: Disclosed herein are novel pharmaceutical formulations of a neurokinin-1 (NK-1) receptor antagonist suitable for parenteral administration including intravenous administration. Also included are formulations including both the NK-1 receptor antagonist and dexamethasone sodium phosphate. The pharmaceutical formulations are stable oil-in-water emulsions for non-oral treatment of emesis and are particularly useful for treatment of subjects undergoing highly emetogenic cancer chemotherapy.

Abstract: The disclosed computer-implemented method may include displaying vehicle environment awareness. In some embodiments, a visualization system may display an abstract representation of a vehicle's physical environment via a mobile device and/or a device embedded in the vehicle. For example, the visualization may use a voxel grid to represent the environment and may alter characteristics of shapes in the grid to increase their visual prominence when the sensors of the vehicle detect that an object is occupying the space represented by the shapes. In some embodiments, the visualization may gradually increase and reduce the visual prominence of shapes in the grid to create a soothing wave effect. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: The present invention provides a method of enabling a provision of public warning system, PWS, messages to a user equipment, UE, device via a non-3GPP radio network, the method comprising establishing an internet protocol security, IPSec, tunnel connection from the UE device to a non-3GPP interworking function, N3IWF, via a non-3GPP, N3GPP, radio access technology, requesting from a first core network, CN, entity a provision of public warning system, PWS, messages; and providing the first CN entity with information about a location of the UE device.

Abstract: A compound (as represented by formula I) serving as an Src homology region 2-containing protein tyrosine phosphatase 2 (SHP2) inhibitor, as well as a pharmaceutical composition thereof, a preparation method therefor, and a use in treating an SHP2 mediation diseases. The compounds of formula I exerts an effect by means of participating in the regulation of multiple processes such as cell proliferation, apoptosis, migration, and angiogenesis.

Abstract: The present invention relates to a novel compound, which has cancer therapeutic activity. The present invention also relates to a preparation method for the compound and a pharmaceutical composition comprising the compound.

Abstract: An analog-to-digital converting device includes N-stage first analog-to-digital converters (ADCs), a second ADC, a first calibration circuit, a data recovery circuit and an output circuit. The N-stage first ADCs has a first sampling frequency that is (N+1)/N times of a second sampling frequency, and converts an input signal into first quantized outputs. The second ADC has the second sampling frequency, and converts the input signal into a second quantized output. The first calibration circuit calibrates offsets of the first quantized outputs and the second quantized output to generate third quantized outputs and a fourth quantized output. The data recovery circuit outputs, by the second sampling frequency, one of the third quantized outputs as a fifth quantized output, and subtracts the fifth quantized output from the fourth quantized output to generate output data. The output circuit generates an output signal according to the third quantized outputs and the output data.

Abstract: Disclosed herein are novel pharmaceutical formulations of a neurokinin-1 (NK-1) receptor antagonist suitable for parenteral administration including intravenous administration. Also included are formulations including both the NK-1 receptor antagonist and dexamethasone sodium phosphate. The pharmaceutical formulations are stable oil-in-water emulsions for non-oral treatment of emesis and are particularly useful for treatment of subjects undergoing highly emetogenic cancer chemotherapy.

Abstract: The disclosed computer-implemented method may include displaying vehicle environment awareness. In some embodiments, a visualization system may display an abstract representation of a vehicle's physical environment via a mobile device and/or a device embedded in the vehicle. For example, the visualization may use a voxel grid to represent the environment and may alter characteristics of shapes in the grid to increase their visual prominence when the sensors of the vehicle detect that an object is occupying the space represented by the shapes. In some embodiments, the visualization may gradually increase and reduce the visual prominence of shapes in the grid to create a soothing wave effect. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: The present disclosure provides a food processor, including: a cup body; a cup cover detachably connected to an upper end of the cup body, the cup cover including a pumping opening communicating with an inner cavity of the cup body, and being provided with a cover handle; and a vacuum pumping device detachably connected to the cup cover, the vacuum pumping device including a pumping hole and an exhaust hole, the pumping hole being configured to communicate with the pumping opening after the vacuum pumping device is mounted on the cup cover. The food processor has a simplified vacuum pumping structure, improving the use convenience of the food processor.

Abstract: The present disclosure provides a spiral blade, a grinding component and a food processor. The spiral blade includes: a spiral blade body, and the spiral blade body includes a feeding area used for feeding, a grinding area connected with the feeding area and a discharging area connected with the grinding area; and a plurality of spiral ribs are arranged on the grinding area, and a cleaning structure is arranged on the discharging area. The spiral blade is applied to the food processor and is only used for grinding food rather than extruding juice and discharging residues, therefore its structure is relatively simple, meanwhile, as a cleaning structure is arranged on the discharging area, the cleaning structure can be used for pushing the crushed food to a predetermined area.

Abstract: In one embodiment, a method includes generating a simulated sensor based on performance features associated with a sensor. The method includes determining a placement indicator specifying a location and orientation of the simulated sensor on a vehicle in a virtual environment associated with the vehicle. The method includes simulating, based on the performance features associated with the sensor, behavior of one or more emissions originating from the simulated sensor in the virtual environment. For each emission, the simulating includes determining an interaction of the emission with one or more simulated objects in the virtual environment. The method includes providing a representation of a capability of the sensor based on the simulated behavior of the emissions.

Abstract: Methods and apparatus determine offcut angle of a crystalline sample using electron channeling patterns (ECPs), wherein backscattered electron intensity exhibits angular variation dependent on crystal orientation. A zone axis normal to a given crystal plane follows a circle as the sample is azimuthally rotated. On an ECP image presented with tilt angles as axes, the radius of the circle is the offcut angle of the sample. Large offcut angles are determined by a tilt technique that brings the zone axis into the ECP field of view. ECPs are produced with a scanning electron beam and a monolithic backscattered electron detector; or alternatively with a stationary electron beam and a pixelated electron backscatter diffraction detector. Applications include strain engineering, process monitoring, detecting spatial variations, and incoming wafer inspection. Methods are 40× faster than X-ray diffraction. 0.01-0.1° accuracy enables semiconductor applications.

Abstract: Provided is a method for treatment of lung squamous cell carcinoma (LUSC) by administering to an individual in need of treatment one or more inhibitors of the RTK-Ras signaling pathway. The LUSC cells may carry a mutation in a KMT2D gene. The inhibitors of the RTK-Ras signaling pathway are SHP2 inhibitors or epidermal growth factor receptor (EGFR) inhibitors. Combinations of the SHP2 inhibitors and EGFR inhibitors can be used.

Abstract: Disclosed herein are novel pharmaceutical formulations of a neurokinin-1 (NK-1) receptor antagonist suitable for parenteral administration including intravenous administration. Also included are formulations including both the NK-1 receptor antagonist and dexamethasone sodium phosphate. The pharmaceutical formulations are stable oil-in-water emulsions for non-oral treatment of emesis and are particularly useful for treatment of subjects undergoing highly emetogenic cancer chemotherapy.

Abstract: An analog to digital converter (ADC) device includes ADC circuits, a calibration circuit and a controlling circuit. The ADC circuits are configured to generate first quantized outputs according to clock signals. The calibration circuit is configured to perform at least one error operation according to the first quantized outputs to generate second quantized outputs, and is configured to analyze time difference information of the clock signals according to the second quantized outputs to generate adjustment signals. The controlling circuit is configured to analyze the first quantized outputs to generate at least one control signal to the calibration circuit, wherein the at least one control signal is configured to control the calibration circuit to selectively perform the at least one error operation and selectively analyze the time difference information of the clock signals.

Abstract: Methods and apparatus determine offcut angle of a crystalline sample using electron channeling patterns (ECPs), wherein backscattered electron intensity exhibits angular variation dependent on crystal orientation. A zone axis normal to a given crystal plane follows a circle as the sample is azimuthally rotated. On an ECP image presented with tilt angles as axes, the radius of the circle is the offcut angle of the sample. Large offcut angles are determined by a tilt technique that brings the zone axis into the ECP field of view. ECPs are produced with a scanning electron beam and a monolithic backscattered electron detector; or alternatively with a stationary electron beam and a pixelated electron backscatter diffraction detector. Applications include strain engineering, process monitoring, detecting spatial variations, and incoming wafer inspection. Methods are 40× faster than X-ray diffraction. 0.01-0.1° accuracy enables semiconductor applications.

Abstract: An analog to digital converter (ADC) device includes ADC circuits, a calibration circuit and a skew adjusting circuit. The ADC circuits convert an input signal according to clock signals, to generate first quantized outputs. The calibration circuit calibrates the first quantized outputs to generate second quantized outputs. The skew adjusting circuit includes an estimating circuit and a feedback circuit. The estimating circuit analyzes the second quantized outputs to generate detection signals, wherein the detection signals are related to time difference information of the clock signals. The skew adjusting circuit outputs the detection signals as adjustment signals, wherein the adjustment signals are configured to reduce a clock skew of the ADC circuits. The feedback circuit analyzes the detection signals generated by the estimating circuit, to generate a feedback signal to the estimating circuit, wherein the estimating circuit is configured to adjust the detection signals according to the feedback signal.

Abstract: An image sensor includes a semiconductor substrate having a first surface and a second surface, a pixel element isolation film extending through an interior of the semiconductor substrate and defining a plurality of active pixels in the semiconductor substrate, and a dummy element isolation film extending through the interior of the semiconductor substrate and extending along at least one side of the active pixels in a plan view and defining a plurality of dummy pixels in the semiconductor substrate. The pixel element isolation film may have a first end that is substantially coplanar with the first surface and has a first width in a first direction parallel to the first surface, and the dummy element isolation film has a first end that is substantially coplanar with the first surface and has a second width that is greater than the first width of the pixel element isolation film.