Abstract: The present invention relates i.a. to a recombinant avian coronavirus spike protein or fragment thereof comprising a mutation at amino acid position 267 to Cysteine. Further, the present invention relates to an immunogenic composition comprising an avian coronavirus with such spike protein.

Abstract: A device for transporting a medium includes at least one channel which extends in an axial direction and through which the medium is guided. The channel is enclosed by an electrically conductive inner envelope that is connected to a first potential equalization conductor. An electrically conductive outer envelope is provided between the channel and an electrically conductive outer casing and is connected to an electrically conductive second potential equalization conductor. Arranged between the channel and the outer envelope is an electrically insulating intermediate layer which is produced from heat-insulating material.

Abstract: A toothbrush head having a bristle surface with tufts of bristles extending therefrom comprising: first tufts of a mixture of co-extruded bristles and unitary bristles located adjacent to the distal end of the bristle surface; second tufts comprising a mixture of co-extruded bristles and unitary bristles located adjacent to the proximal end of the bristle surface; third tufts comprising tapered bristles located adjacent to the widthways opposite sides of the bristle surface; and fourth tufts comprising a mixture of co-extruded bristles and tapered bristles longer than the co-extruded bristles located as a cluster of fourth tufts widthways between the third tufts and longitudinally between the first and second tufts.

Abstract: A toothbrush head having a bristle surface with tufts of bristles extending therefrom comprising: first tufts of a mixture of co-extruded bristles and unitary bristles located adjacent to the distal end of the bristle surface; second tufts comprising a mixture of co-extruded bristles and unitary bristles located adjacent to the proximal end of the bristle surface; third tufts comprising tapered bristles located adjacent to the widthways opposite sides of the bristle surface; and fourth tufts comprising a mixture of co-extruded bristles and tapered bristles longer than the co-extruded bristles located as a cluster of fourth tufts widthways between the third tufts and longitudinally between the first and second tufts.

Abstract: A toothbrush head with bristles comprising tapered and non-tapered bristles, in which the non-tapered bristles extend to two different lengths from the face, being a first greater length LN1 and a second shorter length LN2. In a preferred embodiment non-tapered bristles are combined with tapered bristles in tufts which are inclined in opposite directions away from and towards the grip handle.

Abstract: A toothbrush wherein longitudinally between its neck region and the grip handle is a an undulating region of transverse limbs integrally linked by folds with troughs between the limbs, the troughs containing a thermoplastic elastomer material bonded to the plastic material of said limbs with a ShoreA hardness of 60-70. Specific structures and dimensions of limbs and folds are disclosed.

Abstract: A toothbrush wherein longitudinally between its neck region and the grip handle is a an undulating region of transverse limbs integrally linked by folds with troughs between the limbs, the troughs containing a thermoplastic elastomer material bonded to the plastic material of said limbs with a ShoreA hardness of 60-70. Specific structures and dimensions of limbs and folds are disclosed.

Abstract: A toothbrush with a cleaning zone with bristles, and with a deformable element by which the cleaning zone can be adapted to the shape of the tooth surface by the cleaning force, where the deformable element comprises flexible wings tapering in a wedge shape toward the cleaning zone and with guide elements between them, at least one of the wings and/or guide element is made of a compressible elastic material.

Abstract: A toothbrush head having a bristle carrier, and bristles held in bristle holders, the bristle holders being connected to the bristle carrier by resilient connectors which cause the holders to move resiliently as brushing pressure is applied to the bristles and also cause the bristle holders to rotate. A suitable form of connector follows a conical surface between the bristle holder and bristle carrier.

Abstract: A toothbrush wherein longitudinally between its neck region and the grip handle is a an undulating region of transverse limbs integrally linked by folds with troughs between the limbs, the troughs containing a thermoplastic elastomer material bonded to the plastic material of said limbs with a ShoreA hardness of 60-70. Specific structures and dimensions of limbs and folds are disclosed.

Abstract: A toothbrush head comprising a flexible bristle carrier such as an elastomer or gel pad or flexibly linked segments, on which bristles are mounted, with a support which supports the carrier at its base near the handle and at the opposite tip part, leaving the carrier unsupported thereby in a region longitudinally between these parts, the carrier being flexible such that it can deform under the forces of toothbrushing so that both its longitudinal and widthways sections become distorted. Preferably the support is also flexible.

Abstract: A filling shoe for rotary tablet presses, comprising a filling shoe housing with at least one discharge opening for a starting product which is to be compressed and with a seal for sealing the gap between the die plate and filling shoe housing, which seal can be fastened exchangeably to a bottom wall of the filling shoe housing. In order to make it possible to achieve shorter downtimes when changing the seals, the seal in the mounted state is fastened to the bottom wall by means of magnetic force. Changing the seal can then take place, if appropriate even without any further aids, by overcoming the magnetic holding force and replacing the seal with a new seal. The invention also relates to the seal for sealing the gap, which seal can be fastened according to the invention by means of magnetic elements.

Abstract: A toothbrush in which at least some of the bristles are linked together at their ends proximate to the head by a web in the toothbrush head, with a pad of a resilient elastomeric material adjacent to the web. When pressure is applied to the bristles this pressure is communicated to the web, and the web bears upon the pad, and communicates the pressure to the pad of elastomeric material. By the toothbrush excessive pressure between the teeth and the bristles during toothbrushing may be relieved.

Abstract: A toothbrush head in which the fixed ends of the bristles are embedded in a mass of a polyurethane gel material incorporated in the head. Typical nylon materials as used for toothbrush bristles are found to bind with polyurethane gels so that advantageously holders for the bristles need not be used. A moulding process is also provided for making the toothbrush head.

Abstract: A brush head, in particular a toothbrush, with a base carrier (1) formed from a soft elastic material in which connecting elements comprising separate support rings (2) separated from one another and bearing a plurality of bristle tufts (4) are embedded, each of the rings having a bristle tuft threaded through. Preferably the bristle tuft can move axially in the support ring and is supported resiliently by the soft elastic material.