Patents by Inventor Hansjorg Eibl

Hansjorg Eibl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10251838
    Abstract: The invention relates to stereospecific lipids for the locoregional therapy with long-term circulating stimuli-sensitive nanocarrier systems. A preferred embodiment thereof is a thermosensitive liposome for treating tumors, especially urinary bladder tumors and other localized tumors.
    Type: Grant
    Filed: June 18, 2014
    Date of Patent: April 9, 2019
    Assignee: THERMOSOME GMBH
    Inventor: Hansjörg Eibl
  • Publication number: 20160136092
    Abstract: The invention relates to stereospecific lipids for the locoregional therapy with long-term circulating stimuli-sensitive nanocarrier systems. A preferred embodiment thereof is a thermosensitive liposome for treating tumors, especially urinary bladder tumors and other localized tumors.
    Type: Application
    Filed: June 18, 2014
    Publication date: May 19, 2016
    Applicant: THERMOSOME GmbH
    Inventor: Hansjörg Eibl
  • Patent number: 9326989
    Abstract: The invention relates to the use of oleyl phosphocholine and oleyl-phospho-(N.N.-dimethyl-N-ethyl)-ethyl-ammonium for the long-term and continuous treatment of serious illnesses, such as cancer, leishmaniasis, ehrlichiosis, multiple sclerosis and psoriasis, in addition to other indications mentioned in the application.
    Type: Grant
    Filed: March 26, 2008
    Date of Patent: May 3, 2016
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventor: Hansjörg Eibl
  • Patent number: 8828972
    Abstract: The invention relates to novel medicament formulations containing, as active ingredients, alkylphosphocholines and the like, alkyl-alkanediol-phosphocholines and the like, and (ether)lysolecithins and the like, in different forms of embodiment. The active ingredients are integral constituents of liposomes, also containing cholesterol and the like and a negative charge carrier. The medicament formulations are especially suitable for the treatment and/or prophylaxis of cancer, protozoan diseases such as leishmaniasis and amoebic diseases, acariasis and diseases caused by arthropods, and bacterial diseases, such as ehrlichiosis. Ocular diseases accompanied by uncontrolled cellular processes can also be advantageously influenced.
    Type: Grant
    Filed: October 19, 2005
    Date of Patent: September 9, 2014
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Hansjörg Eibl, Susanne Christine Wieland-Berghausen, Jean Steffan
  • Patent number: 8273727
    Abstract: The present invention relates to novel phosphoric triesters which comprise apolar lipid structures.
    Type: Grant
    Filed: September 2, 2009
    Date of Patent: September 25, 2012
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventor: Hansjörg Eibl
  • Publication number: 20120027812
    Abstract: The invention relates to ophthalmological implants which comprise alkylphosphocholines. Implants of this type may in particular advantageously be used for the prophylaxis of aftercataract.
    Type: Application
    Filed: February 8, 2010
    Publication date: February 2, 2012
    Inventors: Kirsten Eibl-Lindner, Anselm Kampik, Hansjörg Eibl
  • Publication number: 20100260683
    Abstract: The invention relates to a thermolabile liposome with controlled release temperature for the liposome content, which is essentially formed by at least one phosphatidyl choline with a main transition temperature ranging from 0 to 80° C. and 2 to 15 percent by weight of phosphatidyl oligoglycerin.
    Type: Application
    Filed: June 29, 2010
    Publication date: October 14, 2010
    Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENCHAFTEN E.V.
    Inventors: Hansjorg EIBL, Lars LINDNER
  • Publication number: 20100254909
    Abstract: The invention relates to a thermolabile liposome with a controlled release temperature for the liposome content, in particular a liposome which is stable at 37° C. in serum and with a controlled release temperature of between 40 and 80° C.
    Type: Application
    Filed: June 17, 2010
    Publication date: October 7, 2010
    Inventors: Hansjorg EIBL, Lars H. Lindner
  • Publication number: 20100144676
    Abstract: The invention relates to the use of oleyl phosphocholine and oleyl-phospho-(N.N.-dimethyl-N-ethyl)-ethyl-ammonium for the long-term and continuous treatment of serious illnesses, such as cancer, leishmaniasis, ehrlichiosis, multiple sclerosis and psoriasis, in addition to other indications mentioned in the application.
    Type: Application
    Filed: March 26, 2008
    Publication date: June 10, 2010
    Applicant: Max-Planck-Gesellschaft zur Foerderung Der Wissenschaften e.V.
    Inventor: Hansjörg Eibl
  • Publication number: 20100086583
    Abstract: The present invention relates to novel phosphoric triesters which comprise apolar lipid structures.
    Type: Application
    Filed: September 2, 2009
    Publication date: April 8, 2010
    Applicant: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventor: Hansjörg EIBL
  • Publication number: 20090324704
    Abstract: The present invention relates to lipid-analogous phosphoric acid compounds and in particular phosphoric triesters, phosphoric diester amides and phosphoric diesters. These are preferably cationic phospholipids preferably having at least one free hydroxyl group.
    Type: Application
    Filed: June 25, 2007
    Publication date: December 31, 2009
    Applicant: Max-Planck-Gesellschaft zur Foerderung Der Wissenschaften e.V.
    Inventor: Hansjörg Eibl
  • Publication number: 20090312440
    Abstract: The invention concerns a pharmaceutical preparation which improves penetration of active substances through the tissue membrane or barrier of the target organ.
    Type: Application
    Filed: January 21, 2009
    Publication date: December 17, 2009
    Applicants: Max-Planck-Gesellschaft Zur Foerderung Der Wissenshaften E.V., Genzyme Corporation
    Inventors: Hansjorg EIBL, Peter Hoffman
  • Publication number: 20080003277
    Abstract: The invention concerns a pharmaceutical preparation which improves penetration of active substances through the tissue membrane or barrier of the target organ.
    Type: Application
    Filed: March 12, 2007
    Publication date: January 3, 2008
    Applicants: Max-Planck-Gesellschaft Zur Foerderung Der Wissenshaften E.V., Genzyme Corporation
    Inventors: Hansjorg Eibl, Peter Hoffmann
  • Publication number: 20060165767
    Abstract: The invention relates to a thermolabile liposome with a controlled release temperature for the liposome content, in particular a liposome which is stable at 37° C. in serum and with a controlled release temperature of between 40 and 80° C.
    Type: Application
    Filed: September 12, 2003
    Publication date: July 27, 2006
    Inventors: Hansjorg Eibl, Lars Lindner
  • Publication number: 20060039963
    Abstract: The present invention relates to novel phosphoric triesters which comprise apolar lipid structures.
    Type: Application
    Filed: October 1, 2003
    Publication date: February 23, 2006
    Applicant: Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V.
    Inventor: Hansjorg Eibl
  • Publication number: 20040146535
    Abstract: The invention concerns a pharmaceutical preparation which improves penetration of active substances through the tissue membrane or barrier of the target organ.
    Type: Application
    Filed: November 12, 2003
    Publication date: July 29, 2004
    Inventors: Hansjorg Eibl, Peter Hoffmann
  • Publication number: 20040137048
    Abstract: The invention relates to a thermolabile liposome with controlled release temperature for the liposome content, which is essentially formed by at least one phosphatidyl choline with a main transition temperature ranging from 0 to 80° C. and 2 to 15 percent by weight of phosphatidyl oligoglycerin.
    Type: Application
    Filed: March 8, 2004
    Publication date: July 15, 2004
    Inventors: Hansjorg Eibl, Lars Lindner
  • Patent number: 6649780
    Abstract: Cationic lipids are provided which are useful in the preparation of liposomes and other lipid vesicle carriers. The lipids of the invention are particularly useful as carriers of nucleic acids and other negatively charged substances, for delivery to cells.
    Type: Grant
    Filed: December 17, 1999
    Date of Patent: November 18, 2003
    Assignees: Valentis, Inc., Max-Planck-Gesellschaft zur Foerderung der Wissaschaften B.V.
    Inventors: Hansjörg Eibl, Jinkang Wang, Yi Lin Zhang
  • Publication number: 20030199476
    Abstract: The invention relates to drug formulations for stimulating leukopoiesis and for treating tumor diseases and protozoal diseases, and acariasis and diseases caused by arthropods, which formulations are characterized in that they comprise an effective mixture composed of a) at least one phospholipid compound of the formula I: 1
    Type: Application
    Filed: May 23, 2003
    Publication date: October 23, 2003
    Inventor: Hansjorg Eibl
  • Patent number: 6506393
    Abstract: The invention concerns a new pharmaceutical agent for oral or topical administration in the treatment of protozoal diseases, in particular of leishmaniasis, which contains as the active substance one or several compounds having the general formula I in which R1 is a saturated or monounsaturated or polyunsaturated hydrocarbon residue with 12 to 20 C atoms and R2, R3 and R4 denote independently of one another hydrogen, a C1-C5 alkyl group, a C3-C6 cycloalkyl group or a C1-C5 hydroxyalkyl group whereby two of the residues R2, R3 and R4 can together form a C2-C5 alkylene group which, if desired, can be substituted with an —O—, —S— or NR5 group, in which R5 is hydrogen, a C1-C5 alkyl group, a C3-C6 cycloalkyl group or a C1-C5 hydroxyalkyl group as well as, if desired the usual pharmaceutical auxiliary, diluting, carrier or/and filling substances.
    Type: Grant
    Filed: March 7, 2001
    Date of Patent: January 14, 2003
    Assignees: Zentaris AG, Max-Planck Gesellschaft zur Forderung der Wissenchaften e.V.
    Inventors: Hansjörg Eibl, Clemens Unger, Jürgen Engel