Abstract: Among the various aspects of the present disclosure is the provision of sigma-1 compounds, their radioligands, and related methods of use. The present teachings include compositions for compounds that target the sigma-1 receptor, as well as their radioligands. The present teachings also include a method to assess treatment efficacy of a sigma-1 modulator in a subject in need, which can include acquiring medical images after administration of a sigma-1 radioligand, characterizing sigma-1 expression from the acquired images, and assessing treatment efficacy of a sigma-1 modulator in the subject based on the assessed sigma-1 expression. The methods can assess treatment efficacy in neurological diseases, including but not limited to Alzheimer's disease.

Abstract: This disclosure relates generally to CT x-ray imaging systems and methods, and particularly to an inverse geometry with tetrahedron beams. Specifically, a dose efficient and controllable inverse geometry tetrahedron beam CT imaging is disclosed. The disclosed CT geometry includes a linear array of x-ray sources perpendicular to a rotation axis of the CT system and rotates together with a linear detector array extended parallel to the rotation axis. The x-ray emission from each of the sources is collimated into a fan-shaped beams projected to the linear detector array. The intensity of each beam is dynamically adjusted and controlled during the rotation of the source array and the detector array. Such a configuration provides control of x-ray intensity over a selected region of interest in a target object during the rotation even if the region of interest is off from the rotation axis, with efficient dose control.

Abstract: The present disclosure relates to a method for calibrating an articulated robot, a computer device and a non-temporary computer-readable storage medium. The method includes: acquiring desired trajectory information regarding a desired trajectory of the end-effector; acquiring load information regarding a load subjected by the articulated robot, the load including a gravity load, an inertial load and an external load; obtaining, based on the desired trajectory information, joint position data indicating a joint position of the articulated robot; obtaining, based on the joint position data and the load information, end position change data indicating an end position change of the end-effector; and compensating, based on the end position change data, a position error of the end-effector according to a predetermined compensation strategy.

Abstract: The embodiments of the present application discloses a lithium-ion battery and an electrical apparatus. The lithium-ion battery includes an electrolyte solution. The electrolyte solution includes a metal ion, a Stokes radius of the metal ion is smaller than that of a lithium ion, a CB value of the lithium-ion battery satisfies: 1.06?CB?1.32, and the CB value is a ratio of a capacity of a negative-electrode active material per unit area to a capacity of a positive-electrode active material per unit area.

Abstract: A parallel robot includes a base, a moving platform, a plurality of branch chains, a plurality of driving devices, a plurality of transmission devices, a plurality of force/torque sensors, and a control device. The transmission device includes an output end. Each branch chain includes a first end connected to the output end and a second end connected to the moving platform. The driving device is configured to drive the transmission device to move. The force/torque sensor is configured to sense the force and/or torque between the driving device and the output end. The control device is configured to adjust a power of the driving device according to the force and/or torque sensed by the force/torque sensor, a target force or displacement to be loaded on the moving platform, and a preset rule until the force and/or torque sensed by the force/torque sensor matches the target force or displacement.

Abstract: Embodiments of the present application disclose a lithium-ion battery and an electric device. The lithium-ion battery includes an electrolyte including a metal ion, where a reduction potential of the metal ion is higher than a reduction potential of a lithium ion; and a low CB value region, where a CB value of the lithium ion in the low CB value region satisfies: 0<CB<1, and the CB value is a ratio of a capacity of a negative electrode active material per unit area to a capacity of a positive electrode active material per unit area. The lithium-ion battery provided in the present application can effectively solve the problem of lithium deposition in the low CB value region.

Abstract: A method for determining an external force applied to a robotic arm, wherein the robotic arm includes a plurality of links, a plurality of joints and a plurality of 6-DOF force and torque sensors. In the method, inertial property parameters and motion state parameters of each link are determined. An inertial force and an inertial torque at the center of mass of a target link are determined. Forces and torques between the two ends of the target link and the corresponding joints are acquired respectively by the 6-DOF force and torque sensors. The external force applied to the target link is determined according to the inertial force and the inertial torque at the center of mass of the target link, and the forces and the torques between the two ends of the target link and the corresponding joints.

Abstract: The present application provides a real-time interactive video generation method and system, relates to the field of deep learning technology, including acquiring training data including interactive information and video data corresponding to the interactive information; preprocessing the training data to obtain target training data; performing model training including a model pre-training process and a video pre-generation process based on the target training data, wherein the model pre-training process includes a training of a low-resolution image reconstruction model and a training of a super-resolution model, and the video pre-generation process includes performing a pre-generation of a video based on an interactive video generation model to complete a training of the interactive video generation model, the trained interactive video generation model having the low-resolution image reconstruction model and the super-resolution model, the trainings of which have been completed; and generating an interactive

Abstract: Disclosed is a permanent magnetic levitation buffer roller and a control system. The permanent magnetic levitation buffer roller comprises a roller, a permanent magnetic drum, a magnetic base, a positioner, and a release ring. The permanent magnetic drum is fixedly mounted on two ends of the roller. The roller is located on the magnetic base. The magnetic base is magnetically cooperated with the permanent magnetic drum. One side of the magnetic base away from the roller is fixedly provided with an axial rod. The positioner is slidably mounted on the axial rod. One side of the positioner facing the permanent magnetic drum is uniformly provided with at least one air nozzle. At least one release groove is circumferentially disposed on an edge of the release ring. The control system comprises the permanent magnetic levitation buffer roller, a monitoring device, and a control device.

Abstract: A testing device for mechanical properties of a spray anchor net support system, comprising a main frame (100), a lifting and transporting mechanism (200), a mechanical testing mechanism, a testing platform (500), and a monitoring mechanism (600). The lifting and transporting mechanism (200) is arranged on the main frame (100): the testing platform (500) comprises a mold set and a support assembly to be tested (530); the mold set is movably arranged on the main frame (100), and said support assembly (530) is arranged at the bottom end of the mold set, the mechanical testing mechanism is arranged corresponding to said support assembly (530) and is used for implementing a dynamic impact property test or a static mechanical property test on said support assembly (530); and the monitoring mechanism (600) is communicatively connected to the testing platform (500).

Abstract: The present application provide a wind turbine blade lifting device based on an offshore wind turbine unit, including: a clamping assembly and an adjusting assembly, where the clamping assembly includes a clamping box and a plurality of clamping base members, the clamping box is internally provided with a fixing plate, and the plurality of clamping base members are independently provided on both sides of the clamping box; the clamping base members penetrate through a sidewall of the clamping box and extend into the clamping box and are detachably connected to the adjusting assembly provided in the clamping box; the adjusting assembly includes a conveying member, a hydraulic barrel, and a fixing barrel, the conveying member is provided at bottom of the fixing plate, both sides of the conveying member are detachably connected to the plurality of clamping base members, respectively.

Abstract: A projection device includes a housing and a light engine, a circuit board, and a fan that are arranged in the housing. The bottom wall of the housing is provided with an air inlet hole facing the light engine and an air outlet hole. A first gap is formed between a bottom side of the light engine and the bottom wall of the housing, and in communication with the air inlet hole. The circuit board is arranged on a top side of the light engine. A second gap is formed between the circuit board and the light engine, and in communication with the air inlet hole. The fan is configured to drive cooling airflow entering the housing from the air inlet hole to respectively flow through the first gap and the second gap and then flow towards the first radiator, and to be discharged from the air outlet hole.

Abstract: In one aspect, the disclosure relates to compounds methods for treating or preventing diseases associated with aberrant condensation of a biomolecule in a subject, the method including at least the step of contacting one or more cells in the subject with a fusion protein that includes a J domain protein and a targeting molecule, wherein the targeting molecule binds the biomolecule. In one aspect, the biomolecule can be a target protein that may be mutated and/or include one or more intrinsically disordered regions. In another aspect, the targeting molecule can be a nanobody, but other targeting molecules are also contemplated. In still another aspect, the disclosed method is useful for treating and/or preventing cancers such as blood cancers and non-small cell lung cancer. Also disclosed are methods for disrupting condensates in cell culture.

Abstract: A lead-wire frame structure for packaging and a sensor package structure, which are applied to the field of sensor preparation. The lead-wire frame structure comprises: a bonding-pad component and a plurality of pin components, wherein the bonding-pad component is provided with an inward recess in a plane direction of a coplane which is formed by the bonding-pad component and the plurality of pin components. In the plane direction, arc-shaped packaging interfaces for offsetting stresses are formed in an aligned manner on an inner contour of the recess and an outer contour of the recess in the bonding-pad component. In the present application, the bonding-pad component is provided with the inward recess in the plane direction, and the aligned packaging interfaces of the inner contour of the recess and the outer contour of the recess arc designed to be of arc-shaped structures, which can offset internal and external stresses.

Abstract: The present application provides a real-time interactive video generation method and system, relates to the field of deep learning technology, including acquiring training data including interactive information and video data corresponding to the interactive information; preprocessing the training data to obtain target training data; performing model training including a model pre-training process and a video pre-generation process based on the target training data, wherein the model pre-training process includes a training of a low-resolution image reconstruction model and a training of a super-resolution model, and the video pre-generation process includes performing a pre-generation of a video based on an interactive video generation model to complete a training of the interactive video generation model, the trained interactive video generation model having the low-resolution image reconstruction model and the super-resolution model, the trainings of which have been completed; and generating an interactive

Abstract: A method and a system for generating real-time target video are provided, the method includes: acquiring training data including interactive information and video data corresponding to the interactive information; preprocessing the training data to obtain target training data; where the preprocessing includes: performing down-sampling processing on the video data to obtain a plurality of frames of low-resolution images; performing model training to a preset model based on the target training data; the model training includes a model pre-training process and a video pre-generation process, the model pre-training process includes a training of a low-resolution image reconstruction model and a training of a super-resolution model, and the video pre-generation process includes: performing video pre-generation based on the target training data and an interactive video generation model to complete training to the interactive video generation model; and, obtaining an interactive target video through the trained inte

Abstract: Various systems, methods, and devices are described for utilizing artificial intelligence (AI) bot (e.g., a chatbot) to fetch or create content associated with a third-party platform based on an input associated with an electronic device. In an example, systems and methods of AI bot fetching or creating content may include receiving an input, via a user device. The input may be textual, audible, or any other suitable method. Based on the input, one or more content items may be fetched or created. The machine learning model may be utilized to determine context associated with the input. The machine leaning model may determine a number of content items associated with the input and data sources related to the retrieval generators. A result may be presented to a user, where the result may comprise the one or more content items determined.

Abstract: The present application discloses a four-terminal resistance testing structure. A test key includes a resistor string formed by connecting two or more tested resistors in series. Two ends of each tested resistor are respectively provided with one first pad. At least one of the two first pads of each tested resistor is shared as the first pad of an adjacent tested resistor. Each tested resistor includes two force terminals and two sense terminals. The two force terminals are formed by the first pads at the two ends of the tested resistor, and each of the two sense terminals is composed of a pad located at a position adjacent to the corresponding force terminal. The present application can reduce the number of pads and thus save the area on the premise of ensuring the measurement accuracy.

Abstract: Provided is a communication system based on end-to-end data encryption. The system includes a domain controller, an actuator, and a sensor. The sensor is configured to sense vehicle state information and transmit the vehicle state information as sensed to the domain controller through an end-to-end communication protection protocol; and the domain controller is configured to acquire a control instruction based on the vehicle state information as received, and transmit a corresponding control instruction to a corresponding actuator through the end-to-end communication protection protocol. The end-to-end communication protection protocol is additionally provided with a cyclic code that is variable and configured to encrypt information for communication.