Abstract: Provided herein are small molecules that bind to ASH1L and inhibit ASH1L activity, and methods of use thereof for the treatment of disease, including acute leukemia, solid cancers and other diseases dependent on activity of ASH1L.

Abstract: A method of animating a digital character according to facial expressions of a user, comprising the steps of, (a) obtaining a 2D image and 3D depth map of the face of the user, (b) determining expression parameters for a user expression model so that a facial expression of the user-specific expression model represents the face of the user shown in the 2D image and 3D depth map (c) using the expression parameters and an animation prior to determine animation parameters usable to animate a digital character, wherein the animation prior is a sequence of animation parameters which represent predefined animations of a digital character (d) using the animation parameters to animate a digital character so that the digital character mimics the face of the user.

Abstract: An intelligent identification and warning method for an uncertain object of a production line in a digital twin environment, includes: establishing a model library for uncertain physical objects from a non-production line system; adding attribute data to the uncertain physical objects from the non-production line system; importing an established model library and added attribute data for the uncertain physical objects from the non-production line system into a model library of an existing DT production line system; performing auto-detection on an uncertain physical object entering a production line system; performing auto-detection on an actual size of the uncertain physical object entering the production line system; warning a danger for an unsafe object by means of voice prompting, system alarming and information pushing; matching a corresponding three-dimensional (3D) model in the established model library for a safe object; and loading a matched 3D model to the DT production line system.

Abstract: The present disclosure relates to methods, apparatuses, and systems for road warning. In one example method, when using a vehicle to travel, a user may be indicated in advance that a dangerous road exists based on a driving intention of the vehicle and a distance from the dangerous road. The vehicle can start advance warning when it is determined that a driving intention probability of the vehicle to the dangerous road is not less than a specified threshold.

Abstract: A material completeness detection method configured to detect whether materials of a target object in a physical production line are complete, includes: inputting an image of the target object in the physical production line into a material completeness detection algorithm to acquire a first detection result; inputting a virtual model of the target object in a virtual production line into the material completeness detection algorithm to acquire a second detection result, where the virtual production line is a DT of the physical production line; and acquiring a material completeness detection result of the target object based on the first detection result and the second detection result. The embodiments of the present disclosure can realize efficient and accurate material completeness detection.

Abstract: Systems and methods are presented for identifying individuals through facial recognition, voice recognition, or the like, recalling past recorded conversations with the identified individuals, and recording and inventorying conversations with the individuals with mobile devices. In some embodiments, a method is presented. The method may include identifying, at a device, an individual through facial recognition, voice recognition, or a unique RFID. The method may also include recording a conversation with the identified individual, and recalling past relevant recorded conversations based on the identification of the individual, and transmitting the recording of the conversation to a display system configured to display the recording of the event.

Abstract: The present disclosure provides a task migration method, apparatus, electronic device and storage medium, and relates to the technical field of data processing. The method may include: obtaining a task submitted by a user; in the case that the task is a Hadoop task and it is determined that task conversion is to be performed, converting Hadoop parameters in the task into parameters recognizable by a Spark; and injecting a conversion result into a predetermined kit and submitting the predetermined kit to a Spark cluster. The solution of the present disclosure may be applied to reduce the user's workload and enhance the processing efficiency etc.

Abstract: A temperature and pressure sensor includes: a substrate, a first sensing resistor, and a second sensing resistor. The substrate has multiple pressure sensing areas and multiple temperature sensing areas. Two opposite surfaces of each pressure sensing area are respectively provided with the first sensing resistors which are constituted as a pressure detection circuit. When the substrate is stressed and deformed, the first sensing resistors of the pressure sensing area may generate different deformations and different resistance changes, so that a change of an electrical signal is caused and pressure information is output. At least one surface of the temperature sensing area is provided with a first sensing resistor and a second sensing resistor which are constituted as a temperature detection circuit. The pressure detection circuit and the temperature detection circuit may detect pressure and temperature separately and independently.

Abstract: Embodiments of this application disclose a packet processing method and a related apparatus. The method includes: A network device receives n first packets sent by a terminal device, where each first packet includes one first sequence number field, and the first packet is an air interface packet. The network device determines a sending sequence of n second packets based on values of first sequence number fields of the n first packets, where each of the n second packets corresponds to one first packet. The network device sends the n second packets to a management platform or an application server based on the sending sequence.

Abstract: A method for lateral control of a vehicle includes: determining a target steering wheel rotation angle based on a target trajectory of the vehicle and a vehicle pose; determining a steering wheel rotation angle compensation according to the target steering wheel rotation angle and steering data of the vehicle; and controlling steering of the vehicle according to the target steering wheel rotation angle and the steering wheel rotation angle compensation, such that an actual steering angle of the vehicle is consistent with the target steering wheel rotation angle.

Abstract: A method includes providing medical images of a subject for selecting a target image from thereamong, building a 3D image model based on the medical images and the target image with a surgical target site assigned, performing image registration to superimpose the 3D image model on a real-time image of the subject so as to result in a combined image, determining a virtual entry site located on the combined image, connecting the surgical target site and the virtual entry site with a straight line, generating a guiding path extending from the virtual entry site, in a direction away from the surgical target site and along the straight line, and displaying the guiding path for guiding a surgical instrument.

Abstract: A method of clustering spatial data includes receiving a point cloud comprised of a plurality of points defined within three-dimensional (3D) space. The method further includes selecting one or more adaptable clustering parameters and traversing each of the plurality of points in the point cloud and selectively adding each of the points to one or more clusters based on the selected clustering parameters associated with each point.

Abstract: A modified Ni—Ti—Ta dielectric material for multi-layer ceramic capacitor (MLCC) and a low-temperature preparation method thereof are provided. By using characteristics that radii of the Cu2+ ion and (Al½Nb½)4+ ion are close to those of Ni and Ti elements, respectively, Cu2+, Al3+ and Nb5+ ions are introduced into a Ni0.5Ti0.5TaO4 matrix for partial substitution, a negative temperature coefficient of dielectric constant of -220±30 ppm/°C is provided while a sintering temperature is significantly reduced, and deterioration factors of loss caused by sintering aids is reduced, so that the dielectric material applied to radio frequency MLCC with low loss, low cost and good process stability is prepared.

Abstract: There is provided a battery assembly and a medical capsule. The battery assembly comprises: a battery pack comprising at least two batteries connected in series, and a plurality of connectors electrically connected to the battery pack, comprising a positive electrode connector electrically connected to a positive electrode of the battery pack, a negative electrode connector electrically connected to a negative electrode of the battery pack, and an intermediate connector electrically connected to a positive electrode of one of any two adjacent batteries and a negative electrode of the other one of the two adjacent batteries. The battery assembly of the present invention can selectively output the total voltage of the battery pack or output part of the voltage of the battery pack through the plurality of connectors.

Abstract: The present invention provides a method and system for acquiring operating parameters of a photographic lens, including: a control circuit and a storage unit that are configured in the photographic lens, where the control circuit acquires an operating parameter of the photographic lens by using a focusing ring position sensor, a zoom ring position sensor, an aperture ring position sensor, an accelerometer and a gyro sensor; and the control circuit is further connected to a camera or an external data reading device by using a communication interface, to output the operating parameter after data encapsulation in real time.

Abstract: A method of animating a digital character according to facial expressions of a user, comprising the steps of, (a) obtaining a 2D image and 3D depth map of the face of the user, (b) determining expression parameters for a user expression model so that a facial expression of the user-specific expression model represents the face of the user shown in the 2D image and 3D depth map (c) using the expression parameters and an animation prior to determine animation parameters usable to animate a digital character, wherein the animation prior is a sequence of animation parameters which represent predefined animations of a digital character (d) using the animation parameters to animate a digital character so that the digital character mimics the face of the user.

Abstract: Provided are an electronic device, a wireless communication method and a non-transitory computer-readable storage medium. The electronic device comprises a processing circuit, and the processing circuit is configured: to perform a first uplink data transmission to a first transmission point within a channel occupation time after the electronic device successfully accesses an unlicensed frequency band; and to perform a second uplink data transmission to a second transmission point on the basis of an acknowledgement message from the second transmission point in the vicinity of the first transmission point within the remaining time after the first uplink data transmission is completed in the channel occupation time, wherein the acknowledgement message is transmitted to the electronic device by the second transmission point in response to an additional transmission request transmitted to the second transmission point by the first transmission point after completion of the first uplink data transmission.

Abstract: The invention discloses a “line elimination” immunochromatographic strip and its application in CRISPR nucleic acid detection. The invention provides a kit, including the following: 1) Immunochromatographic strip, the immunochromatographic strip includes a sample pad containing a colloidal gold-labeled antibody, an NC membrane containing a T line and a C line, and a absorbent pad in sequence in the flow direction of the sample; the T line is formed by streptavidin; the C line is formed by a secondary antibody of the colloidal gold-labeled antibody; 2) a CRISPR reaction system, the CRISPR reaction system includes a reporter RNA, a crRNA and a Cas protein; the Cas protein is the Cas protein in the class II type V or VI CRISPR system. The experiments of the invention have proved that by combining the CRISPR nucleic acid detection system, the strip in the kit can realize the detection of various specific nucleic acids (pathogens, genes mutations, drug resistance mutations, etc.

Abstract: A hybrid strain sensing system and the method of making such a system provides a thin semiconductor film with strain sensors and signal processing circuits integrated deposited thereon. The semiconductor film may be further processed and then mounted onto a substrate to be used for strain, force, or other related measurements. The system combines the high sensitivity of a semiconductor strain gauge with the high level of integration of semiconductor integrated circuits (IC)s. Both are highly desirable features for applications where miniaturization and/or flexibility are important requirements.

Abstract: An automatic biological sample library, includes a frame, an upper computer, a control system, a liquid nitrogen tank, an insulated chamber, a transfer container, a rotary-disk rotating module, a basket lifting module, a tray shoveling module, a tube picking module and a transfer module. The rotary-disk rotating module, the basket lifting module, the tray shoveling module, the tube picking module and the transfer module are electrically connected to the control system.