Abstract: Methods, systems, and apparatus, including computer-readable media, for environment monitoring and management. In some implementations, information indicating a planned usage level for usage of cloud computing services is accessed by a group of multiple computing environments over a period of time. Usage of cloud computing services is monitored for the group of multiple computing environments. A usage measure indicating an amount of usage of cloud computing services by the group of multiple computing environments is generated over the period of time. A cloud computing usage notification is generated based on the planned usage level and the usage measure. The cloud computing usage notification is provided for presentation by an electronic device.

Abstract: The present invention relates to phenyl [a]indole[2,3-g]quinolizine compounds represented by formula (I), a preparation method therefor, a pharmaceutical composition, and applications thereof. Specific applications are applications in the preparation of drugs for treating diseases related to a proprotein convertase subtilisin Kexin-9 (PCSK9), comprising the applications in the preparation of drugs for treating hyperlipemia, hypercholesterolemia, hypertriglyceridemia, fatty liver deformation, atherosclerosis, obesity and other metabolic diseases.

Abstract: A jet noise suppressor and an airplane are provided. The jet noise suppressor includes a nozzle with a front end, a back end, an interior surface, and an exterior surface, a plurality of struts, and a plurality of vents. Each strut includes a base and a distal end with the base of each strut coupled to the interior surface of the nozzle, and each vent corresponds to a respective strut and is formed within the interior surface of the nozzle between the front end of the nozzle and the base of the respective strut.

Abstract: The present invention includes methods for treating and/or immunizing against Haemophilus influenzae, including nontypeable H. influenzae (NTHi). The methods comprise administering a composition comprising H. influenzae proteins OppA and/or LapB.

Abstract: Disclosed is a method for synthesizing a novel chiral ligand, a metal chelate, a variety of non-natural amino acids, Maraviroc and a key intermediate thereof. In the invention, (R)-2-methyl proline is selected and used as a starting raw material, (S)-?3-amino acid is obtained by asymmetric resolution induced by using a nickel chelate, and Maraviroc is synthesized by using (S)-3-amino-3-phenylpropionic acid as a key intermediate with a high yield and the ee value reaching 98.2% or more. The method of the present invention has widely available materials, mild synthetic process conditions, is easy to control, and produces a product of a high optical purity.

Abstract: A ruler surface structure for clear marks display in a dim light mainly comprises a ruler surface and a brightening layer. The ruler surface is marked with marks which are characters or lines. The brightening layer is laid on the marks to enhance the display and identification effect of the marks. By using the different light sensitivities formed by the brightening layer on the marks and the other regions of the ruler surface, including the functions of light reflection or luminescence, the marks can be clearly displayed and identified in the dim light.

Abstract: A disclosed expansion socket may include a primary slot and a secondary slot, each mounted to a receiver printed circuit board and electrically coupled to a central processing unit via a computing bus. The primary slot may be dimensioned to receive a primary pinout disposed within a primary portion of an edge connector disposed on a connecting edge of a presenter printed circuit board. Likewise, the secondary slot may be positioned and dimensioned to receive a secondary pinout, disposed within a secondary portion of the edge connector, when the primary slot receives the primary portion of the edge connector. Furthermore, the primary pinout and the secondary pinout may each conform to a compact pinout specification that is more compact than a pinout specification defined for the computing bus. Various other systems and methods are also disclosed.

Abstract: Methods and systems are provided for automated graphical prescriptions with deep learning systems. In one embodiment, a method for a medical imaging system comprises acquiring, by the medical imaging system, localizer images of a subject, generating, by a trained neural network system, a graphical prescription using the localizer images, and performing, by the medical imaging system, a scan of the subject according to the graphical prescription. In this way, a desired region of interest of the subject may be accurately scanned with minimal input from an operator of the medical imaging system.

Abstract: A jet noise suppressor and an airplane are provided. The jet noise suppressor includes a nozzle with a front end, a back end, an interior surface, and an exterior surface, a plurality of struts, and a plurality of vents. Each strut includes a base and a distal end with the base of each strut coupled to the interior surface of the nozzle, and each vent corresponds to a respective strut and is formed within the interior surface of the nozzle between the front end of the nozzle and the base of the respective strut.

Abstract: A ruler surface structure for clear marks display in a dim light mainly comprises a ruler surface and a brightening layer. The ruler surface is marked with marks which are characters or lines. The brightening layer is laid on the marks to enhance the display and identification effect of the marks. By using the different light sensitivities formed by the brightening layer on the marks and the other regions of the ruler surface, including the functions of light reflection or luminescence, the marks can be clearly displayed and identified in the dim light.

Abstract: A disclosed expansion card may include a printed circuit board and a hardware accelerator. The hardware accelerator may be disposed on the printed circuit board and may include application-specific hardware circuitry designed to perform a computing task. The hardware accelerator may offload a portion of the computing task from a central processing unit of a computing device by executing, via the application-specific hardware circuitry, the portion of the computing task. The expansion card may also include an edge connector, disposed on a connecting edge of the printed circuit board, that may couple the hardware accelerator to the central processing unit via a computing bus. The edge connector may also include a primary pinout and a secondary pinout that may each conform to a compact pinout specification that may be more compact than a pinout specification defined for the computing bus. Various other systems and methods are also disclosed.

Abstract: Disclosed is a method for synthesizing a novel chiral ligand, a metal chelate, a variety of non-natural amino acids, Maraviroc and a key intermediate thereof. In the invention, (R)-2-methyl proline is selected and used as a starting raw material, (S)-?3-amino acid is obtained by asymmetric resolution induced by using a nickel chelate, and Maraviroc is synthesized by using (S)-3-amino-3-phenylpropionic acid as a key intermediate with a high yield and the ee value reaching 98.2% or more. The method of the present invention has widely available materials, mild synthetic process conditions, is easy to control, and produces a product of a high optical purity.

Abstract: The present invention relates to phenyl [a]indole[2,3-g]quinolizine compounds represented by formula (I), a preparation method therefor, a pharmaceutical composition, and applications thereof. Specific applications are applications in the preparation of drugs for treating diseases related to a proprotein convertase subtilisin Kexin-9 (PCSK9), comprising the applications in the preparation of drugs for treating hyperlipemia, hypercholesterolemia, hypertriglyceridemia, fatty liver deformation, atherosclerosis, obesity and other metabolic diseases.

Abstract: A computer-implemented sonic boom prediction method for use in designing a supersonic aircraft is disclosed herein. The method includes receiving physical parameters and performance parameters for a supersonic aircraft, generating a three-dimensional (3D) flow field around the supersonic aircraft for at least one airspeed using a CFD model in a first region of a near field bounded by a first radial distance and a propagation model in a second region of the near field bounded by the first radial distance and the second radial distance. The 3D flow field generated by the CFD model is used as a boundary condition for the propagation model. The method further includes estimating sonic boom signatures on a ground surface using a long distance sonic boom propagation model that incorporates the 3D flow field estimated by the propagation model as an initial condition. The parameters are adjusted to reduce estimated sonic boom signatures.

Abstract: The present disclosure concerns herbicide granules and powders containing a high-load of fluroxypyr-meptyl. The granules exhibit good storage stability and good herbicidal efficacy when added to water and applied by spray application to control unwanted plant growth.

Abstract: An information processing method and device are disclosed. The information processing method is applied to an information processing device in which a 3D map and a spatial topological structure management-based feature library created in advance for a certain environment are contained, and different users in the certain environment can determine their location. The method includes acquiring a first image taken by a first user; extracting one or more first feature points in the first image to obtain first feature descriptors; obtaining 3D locations of the first feature points based on 3D location of the first user, the first image, and the feature library; determining feature descriptors to be updated based on 3D location of the first user, the 3D locations of the first feature points, the first feature descriptors corresponding to the first feature points, and existing feature descriptors in the feature library; and updating the feature library.

Abstract: A controller that is operatively connected with a magnet assembly, which defines a target volume; and an image processor, which is configured to obtain calibration data from the controller; map B1 transmit intensity from the magnet assembly to the target volume, based on the calibration data; calculate a B1 transmit shading correction based at least on the map of B1 transmit intensity and on pulse sequence parameters; obtain k-space data of an imaging subject within the target volume from the controller operating the magnet assembly based on the pulse sequence parameters; develop an MR image from the k-space data; and apply the B1 transmit shading correction to the MR image.

Abstract: The present disclosure concerns herbicide granules and powders containing a high-load of fluroxypyr-meptyl. The granules exhibit good storage stability and good herbicidal efficacy when added to water and applied by spray application to control unwanted plant growth.

Abstract: A jet noise suppressor including a nozzle having a front end and an opposed rear end, spokes extending radially inward from the nozzle, the spokes defining vents, and a center-body connected to the spokes and in fluid communication with the vents, the center-body being positioned centrally within the nozzle and including a closed front end and an open rear end, wherein the front end of the nozzle entrains a first ambient airflow passing through the nozzle and exiting the rear end of the nozzle proximate a periphery of the nozzle, and wherein the vents entrain a second ambient airflow passing through the center-body and exiting the rear end of the nozzle proximate a center of the nozzle.