Abstract: Embodiments disclosed herein provide compositions, methods, and uses for respiratory syncytial viruses (RSV) and immunogenic compositions thereof. Certain embodiments provide RSV having a mutated NS1 protein, where the mutation causes the uncoupling of the NS1 protein's replication and type I interferon (IFN) antagonist functions. In some embodiments, this uncoupling can produce virions capable of inducing a strong, long-lasting innate immune response while maintaining its ability to replicate in vitro. Also provided are methods for amplifying RSV in host cells, wherein amplified RSV has mutated NS1 protein in which the protein's replication and IFN antagonistic functions are uncoupled. In certain embodiments, the amplified RSV having mutated NS1 protein is formulated into immunogenic compositions, including vaccines. Other embodiments provide methods for inducing an effective immune response against RSV infection in a subject.

Abstract: A vehicle power supply device that includes a control unit that performs at least a quick charging control which causes the first voltage converter to perform the charging operation and causes the second voltage converter to perform the charging operation, and a charging/discharging control which causes the first voltage converter to perform the charging operation and causes the second voltage converter to perform the discharging operation.

Abstract: An image processing method includes: performing an equirectangular projection on a first fisheye image and a second fisheye image to obtain a first equirectangular image and a second equirectangular image; swapping positions of a left-half image of the second equirectangular image and a right-half image of the second equirectangular image to obtain a third equirectangular image; rotating the first equirectangular image and the third equirectangular image by 90 degrees in a spherical coordinate system to obtain a first rotated image and a second rotated image; stitching the first rotated image and the second rotated image to obtain a stitched image; and rotating the stitched image by ?90 degrees in the spherical coordinate system to obtain a panoramic image.

Abstract: A baby cry detection circuit includes a signal capturing circuit, a characteristics capturing circuit and a determination circuit. When a strength of a voice signal is greater than a threshold, the signal capturing circuit captures the voice signal to generate a voice segment signal. A time period of a voice segment corresponding to the voice segment signal is within a predetermined range. The characteristics retrieving circuit, coupled to the signal capturing circuit, captures a plurality of characteristic values of the voice segment signal. The determination circuit, coupled to the characteristics capturing circuit, determines whether the voice segment corresponding to the voice segment signal is a baby cry according to the characteristic values.

Abstract: A feedback photoplethysmography measuring device is provided, including: a measuring device that measures a human body to obtain a photoplethysmography signal; an analog/digital conversion unit that converts the photoplethysmography signal measured by the measuring device to a photoplethysmography value which is a digital value; a variation-degree calculation unit that calculates a photoplethysmography variation value according to the photoplethysmography value converted by the analog/digital conversion unit; and a feedback emitted light amplitude adjustment unit that controls the measuring device according to a plurality of preset control values or the adjusted photoplethysmography variation value calculated by the variation-degree calculation unit, and adjusts the photoplethysmography variation value to a minimum variation value.

Abstract: A flip-chip image-sensor package includes a substrate, a coverglass, a conductive layer, and an image sensor. The substrate has an aperture therethrough and a first region and a second region each at least partially surrounding the aperture. The aperture has a first width defined by a boundary of the first region, and a second width defined by a boundary of the second region, wherein the second width exceeds the first width. The coverglass spans the aperture and is located on a top surface of the first region. The conductive layer adjoins the substrate. The image sensor is located beneath the coverglass and is electrically connected to the conductive layer.

Abstract: A method for facilitating a data update is performed. The method includes by a source communication apparatus initiating the data update, establishing a communication link with a target communication apparatus by periodically polling, and transmitting encrypted update data to the target communication apparatus through the interface module. The method further includes by the target communication apparatus after the encrypted update data is completely received operating by executing a first set of instructions in the first storage space and when the data update concludes operating by executing a second set of instructions in the second storage space.

Abstract: An apparatus and a method for noninvasive and caffless blood pressure measurement are provided. The apparatus includes: a photoplethysmography (PPG) amplitude calculation unit, a time difference calculation unit, a velocity calculation unit, and a calculation unit. The method includes the following steps: calculating amplitude differences between characteristic points of a PPG waveform; calculating differences between a time point of a peak of an electrocardiography (ECG) waveform and a time point of each of the characteristic points of the PPG waveform; calculating differences between time points of the characteristic points of the PPG waveform; performing calculation according to the length of a hand and an ECG-PPG time difference to obtain a pulse wave velocity (PWV); and performing calculation according to the PWV, one of the characteristic point amplitude difference, and one of the characteristic point time difference to obtain a systolic/diastolic blood pressure estimate.

Abstract: The present invention provides a method of determining and treating amyotrophic lateral sclerosis (ALS) in a subject, comprising the following steps: (1) measuring a concentration of an autoantibody against high mobility group box 1 protein (HMGB1) in a biological sample from the subject; and (2) administering an effective amount of ALS-treating drug to the subject whose measured concentration of the autoantibody against HMGB1 is higher than 0.874 ?g/ml.

Abstract: A continuous autofocus system includes an image generation portion including a lens, an autofocus voice coil motor for translating the lens with respect to an image sensor capable of generating image data. The autofocus system further includes a driver IC for controlling the autofocus voice coil motor based on the image data, wherein the image data is directly transmitted to the driver IC thereby continuously maintaining a focused image generated by the image generation portion.

Abstract: The present invention provides a method of determining and treating amyotrophic lateral sclerosis (ALS) in a subject, comprising the following steps: (1) measuring a concentration of an autoantibody against high mobility group box 1 protein (HMGB1) in a biological sample from the subject; and (2) administering an effective amount of ALS-treating drug to the subject whose measured concentration of the autoantibody against HMGB1 is higher than 0.874 ?g/ml.

Abstract: A signal-strength enhancing structure for use in a mobile communication device, includes a mobile casing having an accommodation plate for receiving the mobile communication device thereon and a lateral portion extending outwardly from a periphery confining the accommodation plate to enclose the mobile communication device at least partially once placed on the accommodation plate; and a metal element connected to the mobile communication device via a gap-coupled device.

Abstract: A continuous autofocus system includes an image generation portion including a lens, an autofocus voice coil motor for translating the lens with respect to an image sensor capable of generating image data. The autofocus system further includes a driver IC for controlling the autofocus voice coil motor based on the image data, wherein the image data is directly transmitted to the driver IC thereby continuously maintaining a focused image generated by the image generation portion.

Abstract: A method for locating faults in a power network includes reading power network information stored in a database in a data reading step. A power network matrix is created based on the power network information in a power network creating step. A fault current vector is created in a fault current vector creating step. In a fault locating step, a backward substitution is carried out on the fault current vector and the power network matrix to obtain a detection zone vector, and the fault can be located. The fault locating speed of the power network is, thus, increased.

Abstract: Provided is a method for diagnosis of schizophrenia, which comprises: detecting G72 gene product in a body fluid sample from a subject by an assay to determine G72 expression level; comparing said G72 expression level to a baseline G72 expression; and relating the G72 expression level to the patient's risk of schizophrenia by assigning an increased risk of schizophrenia when said G72 expression level is greater than said baseline G72 expression. Through detecting G72 expression level in a peripheral sample, the method can be simply performed by an in vitro assay and accurately predict or diagnose a subject with schizophrenia.

Abstract: A method for determining a signal transmission mode of a plurality of fault indicators includes a data retrieval step, a mode setting step, a number setting step, an analysis step, a first determination step, a calculation step, a second determination step and a mode number increasing step. Based on the above step, the method is able to determine a preferred number of times the fault signals are required to be transmitted between the plurality of fault indicators when a predetermined transmission success rate is met, reducing the energy consumption and prolonging the service life of the indicators.

Abstract: Provided is a method for diagnosis of schizophrenia, which comprises: detecting G72 gene product in a body fluid sample from a subject by an assay to determine G72 expression level; comparing said G72 expression level to a baseline G72 expression; and relating the G72 expression level to the patient's risk of schizophrenia by assigning an increased risk of schizophrenia when said G72 expression level is greater than said baseline G72 expression. Through detecting G72 expression level in a peripheral sample, the method can be simply performed by an in vitro assay and accurately predict or diagnose a subject with schizophrenia.

Abstract: Provided is a method for diagnosis of schizophrenia, which comprises: detecting G72 gene product in a body fluid sample from a subject by an assay to determine G72 expression level; comparing said G72 expression level to a baseline G72 expression; and relating the G72 expression level to the patient's risk of schizophrenia by assigning an increased risk of schizophrenia when said G72 expression level is greater than said baseline G72 expression. Through detecting G72 expression level in a peripheral sample, the method can be simply performed by an in vitro assay and accurately predict or diagnose a subject with schizophrenia.

Abstract: A signal-strength enhancing structure for use in a mobile communication device, includes a mobile casing having an accommodation plate for receiving the mobile communication device thereon and a lateral portion extending outwardly from a periphery confining the accommodation plate to enclose the mobile communication device at least partially once placed on the accommodation plate; and a metal element connected to the mobile communication device via a gap-coupled device.