Abstract: Described herein is a DNA nanotechnology-based platform for the delivery of nucleic acids into cells. The delivery platform relies on compacting cargo mRNA and/or ssDNA into single folded nanostructures that act as the primary structural vehicle material for nanoparticle delivery to cells. The described compositions and methods provide an alternative to packaging mRNA or ssDNA into lipid nanoparticle vehicles, which have complex formulation properties. Also described herein are strategies for protecting mRNA and/or ssDNA cargo and helping these nucleic acid molecules escape the endosome into the cytoplasm using a cationic peptide-PEG coating.

Abstract: A storage device includes: a NAND chip array having a plurality of NAND chips; a ZONE switcher configured to control output of write data to a ZONE cache when a ZONE write command is received; the ZONE cache configured to cache the write data in a cache space corresponding to a ZONE among a plurality of zones; and a ZONE persistence controller configured to control storing, in parallel, the write data in at least two of the plurality of ZONEs cached in the ZONE cache in NAND chips of the NAND chip array corresponding to the plurality of ZONEs.

Abstract: A target volume monitoring method includes obtaining at least one two-dimensional slice image of a target object from an imaging apparatus, where any one of the at least one two-dimensional slice image includes a desired target volume of the target object; obtaining a three-dimensional reference image of the target object; and registering the at least one two-dimensional slice image with the three-dimensional reference image to obtain a registration result, so as to monitor a position of the desired target volume.

Abstract: A magnetic resonance imaging guided radiotherapy system and a magnetic resonance imaging apparatus. The radiotherapy system includes a rotating gantry, a treatment head, and a magnetic resonance imaging apparatus. The rotating gantry is rotatable about a preset rotation axis. The treatment head is rotatable along with rotation of the rotating gantry and configured to emit radiotherapy rays to a target object. The magnetic resonance imaging apparatus includes two magnet assemblies disposed opposite to each other on the rotating gantry in a circumferential direction of the rotating gantry and used to provide a magnetic field for imaging. The magnetic field for imaging has an overlapping region with the radiotherapy rays. A center axis of the magnet assemblies has a preset included angle with the rotation axis, and the closer to the center axis, the greater a distance between inner surfaces of the magnet assemblies disposed opposite to each other.

Abstract: A method for generating the multi-modality image, including obtaining a first modality image of an object to be radiotherapy, where the first modality image is an image generated for the object to be radiotherapy injected with a tracer; and performing a modality conversion on the first modality image to obtain the multi-modality image of the object to be radiotherapy.

Abstract: A heat dissipation system and a medical system are provided. The heat dissipation system includes a circulation pipeline and a cooling device. The circulation pipeline is configured for conveying a cooling medium to a medical system. The medical system includes at least two electric units, and the at least two electric units have different rated cooling temperatures. The cooling device is in communication with the circulation pipeline and is configured for adjusting a temperature of the cooling medium, so as to dissipate heat of the at least two electric units.

Abstract: A tool posture control device includes a plurality of airbags, a gas supply module and a controller. A tool is allowed to be disposed among the airbags. A gas supply module connects the airbags. The controller is electrically connected to the gas supply module and configured to control the gas supply module to provide a plurality of gas to the airbags respectively according to a target bending angle value of the tool.

Abstract: Techniques for inferring whether an event is occurring in 3D space based on 2D image data and for maintaining a camera's calibration are disclosed. An image of an environment is accessed. Input is received, where the input includes a 2D rule imposed against a ground plane. The 2D rule includes conditions indicative of an event. A bounding box is generated and encompasses a detected object. A point within the bounding box is projected from a 2D-space image plane of the image into 3D space to generate a 3D-space point. Based on the 3D-space point, a 3D-space ground contact point is generated. That 3D-space ground contact point is reprojected onto the ground plane of the image to generate a synthesized 2D ground contact point. A location of the synthesized 2D ground contact point is determined to satisfy the conditions.

Abstract: A method for quantifying a structural feature forecast error of a meteorological element based on a graphical similarity is based on the concept of graphical similarity to propose a normalized evaluation technique for a forecast error of a scalar meteorological element such as rainfall, radar reflectivity, temperature, visibility, or wind speed. The method can objectively and truly reflect the true capability of forecasting the meteorological element such as precipitation.

Abstract: Described herein are compositions comprising RNA origami (RNAOG) which include 5-fluorouracil (5FU) or analogues thereof are described which can be used to both directly treat a cancer by inhibiting a biochemical pathway overexpressed in a cancer cell and indirectly treat a cancer by inducing an anti-cancer immune response. Also described herein are methods of using said compositions for treating cancer, inducing an anti-cancer immune response, and/or killing a cancer cell.

Abstract: An identity recognition method, an apparatus, a computer device, and a storage medium are provided. The method includes: obtaining a signal to be identified which includes a millimeter wave signal and an audio signal; performing living feature detection based on the millimeter wave signal and the audio signal, and acquiring a living millimeter wave signal and a living audio signal; performing feature fusion of the living millimeter wave signal and the living audio signal, and acquiring a fusion response diagram of a living voice signal; and performing identity recognition based on the fusion response diagram of the living voice signal.

Abstract: Provided is a liquid crystal handwriting board. The liquid crystal handwriting board includes: a liquid crystal panel, a photosensitive assembly, and a control assembly; wherein the liquid crystal panel includes a first substrate and a second substrate that are opposite; the photosensitive assembly includes a plurality of photosensitive elements; and the control assembly is electrically connected to the liquid crystal panel and the photosensitive assembly, and is configured to determine position information of a pixel region for erasure by detecting position information of target light irradiated to the liquid crystal panel by the photosensitive assembly and supply a pixel voltage to the plurality of pixel electrodes in the pixel region for erasure, such that a voltage difference is present between the plurality of pixel electrodes in the pixel region for erasure and the common electrode.

Abstract: A filter includes an inductor and a capacitor. A first electrode of the capacitor is connected to a first terminal of the inductor. The filter further includes: a base substrate, having at least one functional hole; at least one heat dissipation column, arranged corresponding to the at least one functional hole, where the heat dissipation column is filled in the functional hole corresponding thereto; and a first conductive layer, located on a side of the base substrate. The first conductive layer includes a first conductive line, a first transfer line, and a second conductive layer. The second conductive layer includes a second conductive line and a third conductive line.

Abstract: A storage device includes: a NAND chip array having a plurality of NAND chips; a ZONE switcher configured to control output of write data to a ZONE cache when a ZONE write command is received; the ZONE cache configured to cache the write data in a cache space corresponding to a ZONE among a plurality of zones; and a ZONE persistence controller configured to control storing, in parallel, the write data in at least two of the plurality of ZONEs cached in the ZONE cache in NAND chips of the NAND chip array corresponding to the plurality of ZONEs.

Abstract: A method and device for configuring zones of a Zoned Namespace (ZNS) Solid State Drive (SSD) are provided. The method includes determining types of sizes of zones into which storage space of the ZNS SSD is to be divided and a number of zones having each type of size, and sending information indicating the types of the sizes of the zones and the number of zones having each type of size to the ZNS SSD such that the storage space of the ZNS SSD is divided into zones having different sizes.

Abstract: A nanostructure comprising: a) a base plate sheet comprising a single-duplex layer comprised of DNA origami configured in a planar arrangement, b) a pore configured within the center of the base plate sheet, and c) a multi-duplex layer-thick wall comprising a single-duplex layer comprised of DNA origami that extends downward from the base plate sheet on the periphery of the pore, wherein the base plate sheet comprises a single-stranded DNA region on the bottom surface for lipid membrane anchor modification.

Abstract: The present disclosure provides a method and apparatus for image guidance, a medical device and a computer-readable storage medium. The method for image guidance includes: controlling an imaging mechanism to rotate around a patient positioning mechanism; acquiring a first image in response to that the imaging mechanism is rotated to any one of the capturing angles, the first image being a medical image of the patient captured by the imaging mechanism at a first capturing angle, and the first capturing angle being a capturing angle to which the imaging mechanism is currently rotated; performing, after a second image corresponding to the first image is acquired, image guidance using a combination of the first image and the second image as an indicator of a current position state of the patient.

Abstract: Disclosed is a method for manufacturing a display panel. The method includes: providing a display back plate, wherein the display back plate is provided with a light emitting side; attaching a protective film on the light emitting side of the display back plate, wherein the protective film comprises a transparent adhesive layer disposed on the display back plate and a heavy release film disposed on a side, distal from the display back plate, of the transparent adhesive layer; treating the transparent adhesive layer; and removing the heavy release film, and attaching a functional layer on a side, distal from the display back plate, of the transparent adhesive layer.

Abstract: An image processing method includes: obtaining a guidance image, the guidance image being an image generated based on an image-guided radiation therapy system; and performing image processing on the guidance image to generate a target image, the target image being a computed tomography simulation image corresponding to the guidance image.