Patents by Inventor Hariharan Subramanian

Hariharan Subramanian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12201385
    Abstract: A surgical system includes a shaft having a distal end and a proximal end, the proximal end including a grip, a sensor attached to the distal end of the shaft, at least one visual indicator disposed at the distal end of the shaft, and a controller coupled to the sensor and the at least one visual indicator, the controller actuating the at least one visual indicator according to a signal received from the sensor.
    Type: Grant
    Filed: August 1, 2022
    Date of Patent: January 21, 2025
    Assignee: Briteseed, LLC
    Inventors: Jonathan Gunn, Hariharan Subramanian, Steve McPhilliamy
  • Patent number: 12196770
    Abstract: Cell deposition and staining apparatuses and methods are disclosed herein. In particular, the deposition and staining apparatuses disclosed herein provide low-volume, automated bench top systems for depositing and staining cellular samples on a cytological slide. An example deposition and staining apparatus includes a housing having an access door; a substrate processing holder located within the housing configured to hold one or more substrates and/or one or more substrate cartridges, wherein the substrate processing holder is accessible when the access door is in an open configuration; at least one opening located at least partially above at least a portion of the substrate processing holder; a spray nozzle configured to dispense a gaseous substance into the substrate processing area; a user interface configured receive an input from a user, and in response to receiving the input, cause execution of a pre-programmed protocol; and a waste and/or reagent holder element.
    Type: Grant
    Filed: June 13, 2023
    Date of Patent: January 14, 2025
    Assignees: NanoCytomics, LLC, Northwestern University
    Inventors: Hariharan Subramanian, Michael Verleye, Micah Litow, Justin R. Derbas, Sergey Rozhok, John Hart, Chester Henderson, Rebecca Bartel, Nathan Ray, Anthony White
  • Patent number: 12158475
    Abstract: Systems and methods that enable automated spray deposition of biological specimens carried on microscope slides are described herein. Aspects of the technology are directed, for example, to automated specimen deposition systems and methods of generating high-quality, reproducible specimen-bearing microscope slides in automated processing systems.
    Type: Grant
    Filed: February 6, 2023
    Date of Patent: December 3, 2024
    Assignees: NanoCytomics, LLC, Northwestern University
    Inventors: Jarema Czarnecki, Justin Derbas, Sergey Rozhok, Hariharan Subramanian, Parvathi Viswanathan
  • Patent number: 12108944
    Abstract: A system and method for compensation of angular distortions in a system utilizing light emitters and light sensors disposed on non-parallel jaws may include determining a first point at a first side of a region of interest and a second point at a second side of the region of interest, determining a linear curve including the first and second points, and utilizing the linear curve to remove the angular distortion from the region of interest between the first and second points. A system and method for compensation of angular distortions may alternatively include modeling a non-pulsatile illumination pattern according to the intensities of individual emitters, comparing the pattern according to the model against a non-pulsatile illumination pattern detected using the light sensors, and varying the intensities of the individual emitters based on the comparison until angular distortion has been removed.
    Type: Grant
    Filed: February 27, 2023
    Date of Patent: October 8, 2024
    Assignee: Briteseed, LLC
    Inventors: Amal Chaturvedi, Hariharan Subramanian
  • Publication number: 20240307084
    Abstract: A surgical system used to determine the presence of a vessel within a region proximate to a working end of a surgical instrument includes at least one light emitter disposed at the working end of the surgical instrument, and at least one light sensor disposed at the working end of the surgical instrument and configured to receive light emitted from the at least one light emitter and reflected from the region, the at least one light sensor adapted to generate a signal comprising a non-pulsatile component. The system also includes a controller coupled to the at least one light sensor, the controller an analyzer configured to differentiate between types of nonvascular tissue within the region proximate to the working end of the surgical instrument based on the non-pulsatile component.
    Type: Application
    Filed: May 21, 2024
    Publication date: September 19, 2024
    Inventors: Amal Chaturvedi, Hariharan Subramanian, Jonathan Gunn, Shetha Shukair, Paul Le Rolland
  • Publication number: 20240288122
    Abstract: Aspects of the disclosure are directed to an optimization model for storing liquid hydrogen to power fuel cells in data centers. The optimization model can be based on hydrogen fuel consumption rates in the data center, refueling rates from vendors, refueling response time, storage tank area constraints in the data center, and/or logistical refueling constraints. The optimization model can allow for providing sufficient fuel within a constrained space for backup power in the data center, such as when an emergency arises.
    Type: Application
    Filed: February 24, 2023
    Publication date: August 29, 2024
    Inventors: Dhruv Gupta, Hariharan Subramanian, Priya Chhiba, Varun Sakalkar
  • Patent number: 12066364
    Abstract: Automated cell staining systems and methods are disclosed herein. In particular, the staining systems disclosed herein provide low-volume, automated bench top staining systems for staining biological samples contained on a cytological slide.
    Type: Grant
    Filed: October 3, 2022
    Date of Patent: August 20, 2024
    Assignees: NanoCytomics, LLC, Northwestern University
    Inventors: Sergey Rozhok, Justin R. Derbas, Jarema Czarnecki, Hariharan Subramanian
  • Publication number: 20240230689
    Abstract: Cell deposition and staining apparatuses and methods are disclosed herein. In particular, the deposition and staining apparatuses disclosed herein provide low-volume, automated bench top systems for depositing and staining cellular samples on a cytological slide. An example deposition and staining apparatus includes a housing having an access door; a substrate processing holder located within the housing configured to hold one or more substrates and/or one or more substrate cartridges, wherein the substrate processing holder is accessible when the access door is in an open configuration; at least one opening located at least partially above at least a portion of the substrate processing holder; a spray nozzle configured to dispense a gaseous substance into the substrate processing area; a user interface configured receive an input from a user, and in response to receiving the input, cause execution of a pre-programmed protocol; and a waste and/or reagent holder element.
    Type: Application
    Filed: June 13, 2023
    Publication date: July 11, 2024
    Inventors: Hariharan Subramanian, Michael Verleye, Micah Litow, Justin R. Derbas, Sergey Rozhok, John Hart, Chester Henderson, Rebecca Bartel, Nathan Ray, Anthony White
  • Publication number: 20240183869
    Abstract: An apparatus for depositing and staining a cellular sample, includes a slide processing module comprising a specimen input port (SIP) dock configured to receive a SIP consumable comprising the cellular sample, and position the SIP consumable such that a spray nozzle of the SIP consumable and an air nozzle of the slide processing module are aligned prior to a deposition operation, and a user interface configured receive an input from a user that configures the deposition operation and a staining operation, and an auxiliary systems module, coupled to the slide processing module, comprising a chassis including a removable storage container configured to hold a plurality of bottles comprising one or more of a reagent, a buffer solution, or an ethanol-based fixative, and an electronics subsystem configured to execute, based on the input from the user, a pre-programmed protocol for the deposition operation and the staining operation.
    Type: Application
    Filed: March 31, 2022
    Publication date: June 6, 2024
    Inventors: Hariharan SUBRAMANIAN, John W. HART, Tamara S. SWANSON, Alexander L. BLUESTONE, Margaux HAYES, Michael HENNING, Derek GURBAN, Nick BOOKER, Nick MOUSKOS, Chester HENDERSON, Rebecca BARTEL, Matthew TURNER
  • Patent number: 11992235
    Abstract: A surgical system used to determine the presence of a vessel within a region (102) proximate to a working end (104) of a surgical instrument (106) includes at least one light emitter (110) disposed at the working end (104) of the surgical instrument (106), and at least one light sensor (112) disposed at the working end (104) of the surgical instrument (106) and configured to receive light emitted from the at least one light emitter (110) and reflected from the region (102), the at least one light sensor (112) adapted to generate a signal comprising a first pulsatile component and a second non-pulsatile component.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: May 28, 2024
    Assignee: Briteseed, LLC
    Inventors: Amal Chaturvedi, Hariharan Subramanian, Jonathan Gunn, Shetha Shukair, Paul Le Rolland
  • Patent number: 11969258
    Abstract: A surgical system includes at least one light emitter generating light at a first intensity and an array of light sensors including a least one row of light sensors, individual light sensors in the row of light sensors adapted to generate a signal including a non-pulsatile component. The system also includes a controller coupled to the array of light sensors, the controller including an analyzer to determine the magnitudes of the non-pulsatile components at the individual light sensors in the row of light sensors, to determine if the non-pulsatile component transitions from a higher magnitude to a lower magnitude and from a lower magnitude to a higher magnitude, and if so, to determine if the first intensity should be changed to a second intensity.
    Type: Grant
    Filed: July 17, 2020
    Date of Patent: April 30, 2024
    Assignee: Briteseed, LLC
    Inventors: Amal Chaturvedi, Hariharan Subramanian, Jonathan Gunn, Mayank Vijayvergia, Shetha Shukair, Paul Le Rolland
  • Publication number: 20240133905
    Abstract: Cell deposition and staining apparatuses and methods are disclosed herein. In particular, the deposition and staining apparatuses disclosed herein provide low-volume, automated bench top systems for depositing and staining cellular samples on a cytological slide. An example deposition and staining apparatus includes a housing having an access door; a substrate processing holder located within the housing configured to hold one or more substrates and/or one or more substrate cartridges, wherein the substrate processing holder is accessible when the access door is in an open configuration; at least one opening located at least partially above at least a portion of the substrate processing holder; a spray nozzle configured to dispense a gaseous substance into the substrate processing area; a user interface configured receive an input from a user, and in response to receiving the input, cause execution of a pre-programmed protocol; and a waste and/or reagent holder element.
    Type: Application
    Filed: June 12, 2023
    Publication date: April 25, 2024
    Inventors: Hariharan Subramanian, Michael Verleye, Micah Litow, Justin R. Derbas, Sergey Rozhok, John Hart, Chester Henderson, Rebecca Bartel, Nathan Ray, Anthony White
  • Patent number: 11943104
    Abstract: At a network-accessible service, a request is received from a client to enable access by a migration facilitator to a configuration record collection of the client. A response to a migration candidate identification query is generated using the configuration record collection and transmitted to the facilitator. An indication of a proposal associated with migrating at least a portion of the client's computing environment to a different computing environment with assistance from the facilitator is provided to the client.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: March 26, 2024
    Assignee: Amazon Technologies, Inc.
    Inventors: Hariharan Subramanian, David Samuel Zipkin
  • Publication number: 20240072272
    Abstract: An energy system may include data center computer equipment, a data center power system configured to simultaneously provide power for operation of the data center equipment and power for cooling the data center equipment, fuel cells configured to provide power to the data center power system, an on-site battery storage configured to provide backup power and power conditioning to the fuel cells, an on-site hydrogen storage to provide fuel to the fuel cells, and an excess heat recovery connection configured to transfer a liquid from the data center power system to provide cooling to the fuel cells.
    Type: Application
    Filed: May 18, 2023
    Publication date: February 29, 2024
    Inventors: Priya Chhiba, Thomas Kowalski, Varun Sakalkar, Angad Sandhu, Hariharan Subramanian
  • Patent number: 11916840
    Abstract: Aspects of the present disclosure include methods, apparatuses, and computer readable media for receiving at least one TP packet, computing a current data rate or an end time of a low throughput phase, determining if TP is in the low throughput phase, aggregating the at least one received TP packet or an ACK relating to the at least one received TP packet in response to determining that the TP is not in the low throughput phase, and transmitting the ACK to a sending device.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: February 27, 2024
    Assignee: QUALCOMM Incorporated
    Inventors: Prachi Agrawal, Arnaud Meylan, Vandit Pinal Desai, Rajashekar Chilla, Prasad Gadde, Hariharan Subramanian, Vamsi Dokku, Ryan Michael Chapman, Subash Abhinov Kasiviswanathan, Sean Nicholas Tranchetti, Raul Martinez, Conner Austin Huff
  • Publication number: 20240023889
    Abstract: A surgical system includes at least one light emitter and an array of light sensors disposed at the working end of the surgical instrument, individual light sensors in the array of light sensors adapted to generate a signal comprising a non-pulsatile component. The system also includes a controller coupled to the array of light sensors, the controller including an analyzer configured to determine a curve of the non-pulsatile components of the signals of each of the individual light sensors in the array of light sensors, to identify a plurality of regions of interest along the curve, to determine one or more regions of interest of the plurality of regions of interest to consider further based on one or more measures of closeness between the plurality of regions of interest, and to determine if one or more of the one or more regions of interest are more likely to be associated with a vessel or a tissue based on one or more parameters.
    Type: Application
    Filed: July 7, 2021
    Publication date: January 25, 2024
    Inventors: Venkata Akshay Bhargav Krishna Vadali, Hariharan Subramanian
  • Publication number: 20240027481
    Abstract: Systems and methods that enable automated spray deposition of biological specimens carried on microscope slides are described herein. Aspects of the technology are directed, for example, to automated specimen deposition systems and methods of generating high-quality, reproducible specimen-bearing microscope slides in automated processing systems.
    Type: Application
    Filed: February 6, 2023
    Publication date: January 25, 2024
    Inventors: Jarema Czarnecki, Justin Derbas, Sergey Rozhok, Hariharan Subramanian, Parvathi Viswanathan
  • Publication number: 20230288300
    Abstract: Automated cell staining systems and methods are disclosed herein. In particular, the staining systems disclosed herein provide low-volume, automated bench top staining systems for staining biological samples contained on a cytological slide.
    Type: Application
    Filed: October 3, 2022
    Publication date: September 14, 2023
    Inventors: Sergey Rozhok, Justin R. Derbas, Jarema Czarnecki, Hariharan Subramanian
  • Patent number: 11723600
    Abstract: A surgical system used to determine if a vessel is within a region proximate to a working end of a surgical instrument includes at least one light emitter configured to emit light of two different wavelengths. The system also includes at least one light sensor disposed opposite the at least one light emitter, the at least one light sensor configured to detect light at the two different wavelengths and to provide a signal having a pulsatile and a non-pulsatile component for each wavelength. The system further includes a controller coupled to the at least one light sensor and configured to determine and indicate if the vessel is a ureter within the region proximate to the working end of the surgical instrument based on a ratio and a symmetry of a dip in the non-pulsatile component.
    Type: Grant
    Filed: September 5, 2018
    Date of Patent: August 15, 2023
    Assignee: Briteseed, LLC
    Inventors: Shetha Shukair, Amal Chaturvedi, Hariharan Subramanian
  • Patent number: 11719712
    Abstract: Cell deposition and staining apparatuses and methods are disclosed herein. In particular, the deposition and staining apparatuses disclosed herein provide low-volume, automated bench top systems for depositing and staining cellular samples on a cytological slide. An example deposition and staining apparatus includes a housing having an access door; a substrate processing holder located within the housing configured to hold one or more substrates and/or one or more substrate cartridges, wherein the substrate processing holder is accessible when the access door is in an open configuration; at least one opening located at least partially above at least a portion of the substrate processing holder; a spray nozzle configured to dispense a gaseous substance into the substrate processing area; a user interface configured receive an input from a user, and in response to receiving the input, cause execution of a pre-programmed protocol; and a waste and/or reagent holder element.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: August 8, 2023
    Assignees: NANOCYTOMICS, LLC, NORTHWESTERN UNIVERSITY
    Inventors: Hariharan Subramanian, Michael Verleye, Micah Litow, Justin R. Derbas, Sergey Rozhok, John Hart, Chester Henderson, Rebecca Bartel, Nathan Ray, Anthony White