Patents by Inventor Hartmuth C. Kolb

Hartmuth C. Kolb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PSMA Imaging Agents
    Publication number: 20240425547
    Abstract: Compounds for targeting and agents for imaging, prostate-specific membrane antigen (PSMA) are disclosed. Methods of synthesizing compounds and imaging agents, as well as methods for imaging PSMA are also disclosed. The imaging agents disclosed are suitable for PET and SPECT imaging.
    Type: Application
    Filed: August 20, 2024
    Publication date: December 26, 2024
    Inventors: Eric Wang, Hartmuth C. Kolb, Anna Katrin Szardenings, Changhui Liu, Joseph C. Walsh, Gang Chen, Anjana Sinha, Dhanalakshmi Kasi, Chul Yu, Umesh B. Gangadharmath, Wei Zhang, Tieming Zhao, Vani P. Mocharla
  • PSMA Imaging Agents
    Publication number: 20240409580
    Abstract: Compounds for targeting and agents for imaging, prostate-specific membrane antigen (PSMA) are disclosed. Methods of synthesizing compounds and imaging agents, as well as methods for imaging PSMA are also disclosed. The imaging agents disclosed are suitable for PET and SPECT imaging.
    Type: Application
    Filed: August 20, 2024
    Publication date: December 12, 2024
    Inventors: Eric Wang, Hartmuth C. Kolb, Anna Katrin Szardenings, Changhui Liu, Joseph C. Walsh, Gang Chen, Anjana Sinha, Dhanalakshmi Kasi, Chul Yu, Umesh B. Gangadharmath, Wei Zhang, Tieming Zhao, Vani P. Mocharla
  • PSMA imaging agents
    Patent number: 12139554
    Abstract: Compounds for targeting and agents for imaging, prostate-specific membrane antigen (PSMA) are disclosed. Methods of synthesizing compounds and imaging agents, as well as methods for imaging PSMA are also disclosed. The imaging agents disclosed are suitable for PET and SPECT imaging.
    Type: Grant
    Filed: August 21, 2020
    Date of Patent: November 12, 2024
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Eric Wang, Hartmuth C. Kolb, Anna Katrin Szardenings, Changhui Liu, Joseph C. Walsh, Gang Chen, Anjana Sinha, Dhanalakshmi Kasi, Chul Yu, Umesh B. Gangadharmath, Wei Zhang, Tieming Zhao, Vani P. Mocharla
  • PSMA imaging agents
    Patent number: 12122851
    Abstract: Compounds for targeting and agents for imaging, prostate-specific membrane antigen (PSMA) are disclosed. Methods of synthesizing compounds and imaging agents, as well as methods for imaging PSMA are also disclosed. The imaging agents disclosed are suitable for PET and SPECT imaging.
    Type: Grant
    Filed: August 21, 2020
    Date of Patent: October 22, 2024
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Eric Wang, Hartmuth C. Kolb, Anna Katrin Szardenings, Changhui Liu, Joseph C. Walsh, Gang Chen, Anjana Sinha, Dhanalakshmi Kasi, Chul Yu, Umesh B. Gangadharmath, Wei Zhang, Tieming Zhao, Vani P. Mocharla
  • PSMA Imaging Agents
    Publication number: 20210032286
    Abstract: Compounds for targeting and agents for imaging, prostate-specific membrane antigen (PSMA) are disclosed. Methods of synthesizing compounds and imaging agents, as well as methods for imaging PSMA are also disclosed. The imaging agents disclosed are suitable for PET and SPECT imaging.
    Type: Application
    Filed: August 21, 2020
    Publication date: February 4, 2021
    Inventors: Eric Wang, Hartmuth C. Kolb, Anna Katrin Szardenings, Changhui Liu, Joseph C. Walsh, Gang Chen, Anjana Sinha, Dhanalakshmi Kasi, Chul Yu, Umesh B. Gangadharmath, Wei Zhang, Tieming Zhao, Vani P. Mocharla
  • PSMA Imaging Agents
    Publication number: 20210024574
    Abstract: Compounds for targeting and agents for imaging, prostate-specific membrane antigen (PSMA) are disclosed. Methods of synthesizing compounds and imaging agents, as well as methods for imaging PSMA are also disclosed. The imaging agents disclosed are suitable for PET and SPECT imaging.
    Type: Application
    Filed: August 21, 2020
    Publication date: January 28, 2021
    Inventors: Eric Wang, Hartmuth C. Kolb, Anna Katrin Szardenings, Changhui Liu, Joseph C. Walsh, Gang Chen, Anjana Sinha, Dhanalakshmi Kasi, Chul Yu, Umesh B. Gangadharmath, Wei Zhang, Tieming Zhao, Vani P. Mocharla
  • PSMA imaging agents
    Patent number: 10894807
    Abstract: Compounds for targeting and agents for imaging, prostate-specific membrane antigen (PSMA) are disclosed. Methods of synthesizing compounds and imaging agents, as well as methods for imaging PSMA are also disclosed. The imaging agents disclosed are suitable for PET and SPECT imaging.
    Type: Grant
    Filed: May 9, 2018
    Date of Patent: January 19, 2021
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Eric Wang, Hartmuth C. Kolb, Anna Katrin Szardenings, Changhui Liu, Joseph C. Walsh, Gang Chen, Anjana Sinha, Dhanalakshmi Kasi, Chul Yu, Umesh B. Gangadharmath, Wei Zhang, Tieming Zhao, Vani P. Mocharla
  • PSMA Imaging Agents
    Publication number: 20200377549
    Abstract: Compounds for targeting and agents for imaging, prostate-specific membrane antigen (PSMA) are disclosed. Methods of synthesizing compounds and imaging agents, as well as methods for imaging PSMA are also disclosed. The imaging agents disclosed are suitable for PET and SPECT imaging.
    Type: Application
    Filed: August 21, 2020
    Publication date: December 3, 2020
    Inventors: Eric Wang, Hartmuth C. Kolb, Anna Katrin Szardenings, Changhui Liu, Joseph C. Walsh, Gang Chen, Anjana Sinha, Dhanalakshmi Kasi, Chul Yu, Umesh B. Gangadharmath, Wei Zhang, Tieming Zhao, Vani P. Mocharla
  • Substrate based PET imaging agents
    Patent number: 10821196
    Abstract: The present application is directed to radiolabeled imaging agents comprising a radiolabel, and a substrate, pharmaceutical compositions comprising radiolabeled imaging agents, and methods of using the radiolabeled imaging agents. The present application is further directed to methods of preparing the radiolabeled imaging agent. Such imaging agents can used in imaging studies, such as Positron Emitting Tomography (PET) or Single Photon Emission Computed Tomography (SPECT).
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: November 3, 2020
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Hartmuth C. Kolb, Joseph C. Walsh, Kai Chen, Umesh B. Gangadharmath, Gang Chen, Vani P. Mocharla, Dhanalakshmi Kasi, Peter J. H. Scott, Qianwa Liang
  • System, device and method for preparing tracers and transferring materials during radiosynthesis
    Patent number: 10639608
    Abstract: A system, apparatus, and method for transferring chemical solutions and synthesizing a tracer. For transferring chemical solutions, the system comprises a primary container; a secondary container; a first line in communication with the primary container and the secondary container. The first line facilitates the flow of gas and/or liquid between the primary container and the secondary container. A valve located upstream of the secondary container and downstream of the primary container regulates flow within the first line; a second line in communication with the secondary container. For synthesizing a tracer, the system includes a source of a solution having a radionuclide. A first container has a tracer precursor and is in communication with the source of solution.
    Type: Grant
    Filed: April 12, 2012
    Date of Patent: May 5, 2020
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Umesh B. Gangadharmath, Joseph C. Walsh, Hartmuth C. Kolb, Ricardo Rodriguez, Arkadij M. Elizarov, Carroll Edward Ball
  • PSMA Imaging Agents
    Publication number: 20180258134
    Abstract: Compounds for targeting and agents for imaging, prostate-specific membrane antigen (PSMA) are disclosed. Methods of synthesizing compounds and imaging agents, as well as methods for imaging PSMA are also disclosed. The imaging agents disclosed are suitable for PET and SPECT imaging.
    Type: Application
    Filed: May 9, 2018
    Publication date: September 13, 2018
    Inventors: Eric Wang, Hartmuth C. Kolb, Anna Katrin Szardenings, Changhui Liu, Joseph C. Walsh, Gang Chen, Anjana Sinha, Dhanalakshmi Kasi, Chul Yu, Umesh B. Gangadharmath, Wei Zhang, Tieming Zhao, Vani P. Mocharla
  • PSMA imaging agents
    Patent number: 10011632
    Abstract: Compounds for targeting and agents for imaging, Prostate-specific membrane antigen (PSMA) are disclosed. Methods of synthesizing compounds and imaging agents, as well as methods for imaging PSMA are also disclosed. The imaging agents disclosed are suitable for PET and SPECT imaging.
    Type: Grant
    Filed: August 21, 2012
    Date of Patent: July 3, 2018
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Eric Wang, Hartmuth C. Kolb, Anna Katrin Szardenings, Changhui Liu, Joseph C. Walsh, Gang Chen, Anjana Sinha, Dhanalakshmi Kasi, Chul Yu, Umesh B. Gangadharmath, Wei Zhang, Tieming Zhao, Vani P. Mocharla
  • Formulation, apparatus and method for stabilizing radiopharmaceuticals
    Patent number: 9539350
    Abstract: A formulation for stabilizing a radiopharmaceutical. The formulation includes a radiopharmaceutical (or a pharmaceutically acceptable salt thereof), a gas which has oxygen, a stabilizer, and a solvent.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: January 10, 2017
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Hartmuth C. Kolb, Joseph C. Walsh, Vani P. Mocharla, Fanrong Mu, Umesh Gangadharmath
  • Formulation, apparatus and method for stabilizing radiopharmaceuticals
    Patent number: 9539349
    Abstract: A formulation for stabilizing a radiopharmaceutical. The formulation includes a radiopharmaceutical (or a pharmaceutically acceptable salt thereof), a gas which has oxygen, a stabilizer, and a solvent.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: January 10, 2017
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Hartmuth C. Kolb, Joseph C. Walsh, Vani P. Mocharla, Fanrong Mu, Umesh Gangadharmath
  • PSMA Imaging Agents
    Publication number: 20160304555
    Abstract: Compounds for targeting and agents for imaging, Prostate-specific membrane antigen (PSMA) are disclosed. Methods of synthesizing compounds and imaging agents, as well as methods for imaging PSMA are also disclosed. The imaging agents disclosed are suitable for PET and SPECT imaging.
    Type: Application
    Filed: August 21, 2012
    Publication date: October 20, 2016
    Inventors: Eric WANG, Hartmuth C. KOLB, Anna Katrin INGS, Changhui LIU, Joseph C. WALSH, Gang CHEN, Anjana SINHA, Dhanalakshmi KASI, Chul YU, Umesh B. GANGADHARMATH, Wei ZHANG, Tieming ZHAO, Vani P. MOCHARLA
  • Formulation, Apparatus and Method for Stabilizing Radiopharmaceuticals
    Publication number: 20160243267
    Abstract: A formulation for stabilizing a radiopharmaceutical. The formulation includes a radiopharmaceutical (or a pharmaceutically acceptable salt thereof), a gas which has oxygen, a stabilizer, and a solvent.
    Type: Application
    Filed: April 20, 2016
    Publication date: August 25, 2016
    Inventors: Hartmuth C. Kolb, Joseph C. Walsh, Vani P. Mocharla, Fanrong Mu, Umesh Gangadharmath
  • Formulation, Apparatus and Method for Stabilizing Radiopharmaceuticals
    Publication number: 20160228585
    Abstract: A formulation for stabilizing a radiopharmaceutical. The formulation includes a radiopharmaceutical (or a pharmaceutically acceptable salt thereof), a gas which has oxygen, a stabilizer, and a solvent.
    Type: Application
    Filed: April 20, 2016
    Publication date: August 11, 2016
    Inventors: Hartmuth C. Kolb, Joseph C. Walsh, Vani P. Mocharla, Fanrong Mu, Umesh Gangadharmath
  • Formulation, apparatus and method for stabilizing radiopharmaceuticals
    Patent number: 9345792
    Abstract: A formulation for stabilizing a radiopharmaceutical. The formulation includes a radiopharmaceutical (or a pharmaceutically acceptable salt thereof), a gas which has oxygen, a stabilizer, and a solvent.
    Type: Grant
    Filed: August 15, 2011
    Date of Patent: May 24, 2016
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Hartmuth C. Kolb, Joseph C. Walsh, Vani P. Mocharla, Fanrong Mu, Umesh B. Gangadharmath
  • Novel Substrate Based PET Imaging Agents
    Publication number: 20150182643
    Abstract: The present application is directed to radiolabeled imaging agents comprising a radiolabel, and a substrate, pharmaceutical compositions comprising radiolabeled imaging agents, and methods of using the radiolabeled imaging agents. The present application is further directed to methods of preparing the radiolabeled imaging agent. Such imaging agents can used in imaging studies, such as Positron Emitting Tomography (PET) or Single Photon Emission Computed Tomography (SPECT).
    Type: Application
    Filed: March 10, 2015
    Publication date: July 2, 2015
    Inventors: Hartmuth C. Kolb, Joseph C. Walsh, Kai Chen, Umesh B. Gangadharmath, Gang Chen, Vani P. Mocharla, Dhanalakshmi Kasi, Peter J.H. Scott, Qianwa Liang
  • Substrate based PET imaging agents
    Patent number: 9005577
    Abstract: The present application is directed to radiolabeled imaging agents comprising a radiolabel, and a substrate, pharmaceutical compositions comprising radiolabeled imaging agents, and methods of using the radiolabeled imaging agents. The present application is further directed to methods of preparing the radiolabeled imaging agent. Such imaging agents can used in imaging studies, such as Positron Emitting Tomography (PET) or Single Photon Emission Computed Tomography (SPECT).
    Type: Grant
    Filed: April 30, 2009
    Date of Patent: April 14, 2015
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Hartmuth C. Kolb, Joseph C. Walsh, Kai Chen, Umesh B. Gangadharmath, Gang Chen, Vani P. Mocharla, Dhanalakshmi Kasi, Peter J. H. Scott, Qianwa Liang