Abstract: The present invention relates:—to 2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo-[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide dihydrochloride salt of formula (II): or a tautomer, solvate or hydrate thereof;—to methods of preparing said dihydrochloride salt;—to said dihydrochloride salt for the treatment and/or prophylaxis of a disease;—to the use of said dihydrochloride salt for the preparation of a medicament for the treatment and/or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, more particularly for the treatment or prophylaxis of a cancer, particularly lung cancer, in particular non-small cell lung carcinoma, colorectal cancer, melanoma, pancreatic cancer, hepatocyte carcinoma, pancreatic cancer, hepatocyte carcinoma or breast cancer;—to a pharmaceutical composition comprising said dihydrochloride salt; and—to a pharmaceutical combination comprising said dihydrochloride salt in combination with one or more further pharmaceutical agent

Abstract: The present invention relates to 2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo-[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide dihydrochloride salt of formula (II): or a tautomer, solvate or hydrate thereof; and to its use for the treatment of non-Hodgkin's lymphoma.

Abstract: The present invention relates to 2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo-[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide dihydrochloride salt of formula (II): or a tautomer, solvate or hydrate thereof; and to its use for the treatment of non-Hodgkin's lymphoma.

Abstract: Disclosed are a method and a device for plasma treating workpieces (5). Said workpiece is inserted into a chamber (7) of a treatment station (3), which can be at least partly evacuated, and is positioned within the treatment station by means of a holding element. In order to simultaneously supply at least two chambers with at least one operating means, a flow of the operating means is branched at least once so as to form at least two partial flows (55).

Abstract: The present invention relates:—to 2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo-[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide dihydrochloride salt of formula (II): or a tautomer, solvate or hydrate thereof;—to methods of preparing said dihydrochloride salt;—to said dihydrochloride salt for the treatment and/or prophylaxis of a disease;—to the use of said dihydrochloride salt for the preparation of a medicament for the treatment and/or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, more particularly for the treatment or prophylaxis of a cancer, particularly lung cancer, in particular non-small cell lung carcinoma, colorectal cancer, melanoma, pancreatic cancer, hepatocyte carcinoma, pancreatic cancer, hepatocyte carcinoma or breast cancer;—to a pharmaceutical composition comprising said dihydrochloride salt; and to a pharmaceutical combination comprising said dihydrochloride salt in combination with one or more further pharmaceutical agent

Abstract: A device for plasma treatment of workpieces. The workpiece is placed into a chamber of a processing station that can be at least partially evacuated. The plasma chamber is bounded by a chamber floor, a chamber cover, and a side chamber wall. The plasma chamber is coupled to a device for feeding and/or discharging process gases in a controlled manner. The plasma chamber is further disposed on a rotatable plasma wheel supported on a static base. At least one process gas channel is disposed in the region of the base, bounded at least in regions by a cover. The cover is implemented as part of the plasma wheel and includes at least one connection opening to the process gas channel. The connection opening can be coupled to an inner chamber by a connecting channel and at least one control valve.

Abstract: The device serves for the plasma treatment of workpieces. The workpiece is placed in the chamber of a treatment station which can at least partially be evacuated. The plasma chamber is defined by a chamber bottom, a chamber cover, as well as a lateral chamber wall, and has a positionable gas lance. The gas lance is constructed at least partially of a dielectric.

Abstract: The present invention relates to substituted heterocycles, processes for their preparation, and their use in medicaments, especially for the treatment of inflammatory disease, i.e. asthma, or cancer.

Abstract: The invention relates to a method and a device which are used for the plasma treatment of work pieces. Said work piece is inserted into an at least partially evacuatable chamber of a treatment station (3) and the work piece is positioned inside the treatment station of retaining elements. At least one operating agent is at least partially impinged upon by a transporting device (44) which is displaced together with the treatment station on a closed and rotating transport path.

Abstract: A rollover protection device includes a cassette housing which guides an extendable rollover bar. The cassette housing includes guidances for the rollover bar. The rollover bar is a single shell or multi-shell form part made of fibre reinforced plastic and has shell edge regions which at least partially extend parallel to the extension direction. The cassette housing is a hollow profile made from high strength material and is closed around the rollover bar and the guidance. The guidance is a plastic form part engaging at a shell edge region, is secured within the hollow profile and protrudes from the hollow profile at least downwards.

Abstract: The use of a compound of formula (I) or a salt thereof, where the symbols have the meanings given in the description, for the control of phytopathogenic mircroorganisms of harmful animals.

Abstract: A hollow moulded part 16? made from plastic material containing fibres has at least two hollow chambers 6, 7, 8 between which at least one web 15s provided which bounds the hollow chambers together with outer wall parts 2, 3. The hollow moulded part 16? is a one piece pressed moulded part 1 of a fibre compound plastic material K containing endless fibres in a plastic material matrix. The web 15 also contains endless fibres 14a or 14b. The endless fibres 14a directly extend between the outer wall parts 2, 3 around the hollow chambers 6, 7, 8. The endless fibres 14b are displaced from each other wall part 2, 3 into the web 15 and are anchored to each other.

Abstract: A rollover protection device includes a cassette housing which guides an extendable rollover bar. The cassette housing includes guidances for the rollover bar. The rollover bar is a single shell or multi-shell form part made of fibre reinforced plastic and has shell edge regions which at least partially extend parallel to the extension direction. The cassette housing is a hollow profile made from high strength material and is closed around the rollover bar and the guidance. The guidance is a plastic form part engaging at a shell edge region, is secured within the hollow profile and protrudes from the hollow profile at least downwards.

Abstract: A vehicle body (F) for a passenger car convertible, which has an integrated crosswise partition panel (T) behind the seat anchors (S), on which two retractable roll bars (B) are arranged next to one another, and which vehicle body includes on the back side of the partition panel (T) that is turned away from the seat anchors, exclusively in the upper area of the partition panel, a module carrier (M), which reinforces the partition panel, and which is oriented crosswise to the longitudinal direction of the vehicle, and which extends across the width of the interior of the vehicle body, and which is mounted on the partition panel, which positions the two roll bars (B) on the back side of the partition panel, so that the module carrier and the partition panel together form bar guides (G), whereby the module carrier (M), with the two roll bars (B), is one pre-mounted modular unit (E).

Abstract: The present invention relates to substituted heterocycles, processes for their preparation, and their use in medicaments, especially for the treatment of inflammatory disease, i.e. asthma, or cancer.

Abstract: Disclosed are a method and a device for plasma treating workpieces (5). Said workpiece is inserted into a chamber (4) of a treatment station (17), which can be at least partly evacuated, and at least one part (18) of the treatment station is moved relative to another part (27, 35) thereof in order to help manipulate the workpieces. The movement is carried out in such a way that a shell-shaped chamber wall (18) is positioned relative to a floor (35) of the chamber and relative to a chamber lid (27).

Abstract: A rollover protection device for the passengers of a vehicle having a body and a lateral bulkhead includes a structural unit adapted to be mounted on one side of the vehicle body lateral bulkhead. The structural unit includes at least one extendible rollover bar, and a module beam being connectable in a force transmitting fashion with the lateral bulkhead and the vehicle body. The module beam extends crosswise to the longitudinal direction of the vehicle in an upper region of the lateral bulkhead, and at least one force transmission member contains the at least one rollover bar. The at least one force transmission member supports the module beam at the vehicle body bottom.

Abstract: Disclosed are a method and a device for plasma treating workpieces (5). Said workpiece is inserted into a chamber (7) of a treatment station (3), which can be at least partly evacuated, and is positioned within the treatment station by means of a holding element. In order to simultaneously supply at least two chambers with at least one operating means, a flow of the operating means is branched at least once so as to form at least two partial flows (55).

Abstract: The invention relates to a method and a device which are used for the plasma treatment of work pieces. Said work piece is inserted into an at least partially evacuatable chamber of a treatment station (3) and the work piece is positioned inside the treatment station of retaining elements. At least one operating agent is at least partially impinged upon by a transporting device (44) which is displaced together with the treatment station on a closed arid rotating transport path.

Abstract: A vehicle body (F) for a passenger car convertible, which has an integrated crosswise partition panel (T) behind the seat anchors (S), on which two retractable roll bars (B) are arranged next to one another, and which vehicle body includes on the back side of the partition panel (T) that is turned away from the seat anchors, exclusively in the upper area of the partition panel, a module carrier (M), which reinforces the partition panel, and which is oriented crosswise to the longitudinal direction of the vehicle, and which extends across the width of the interior of the vehicle body, and which is mounted on the partition panel, which positions the two roll bars (B) on the back side of the partition panel, so that the module carrier and the partition panel together form bar guides (G), whereby the module carrier (M), with the two roll bars (B), is one pre-mounted modular unit (E).