Patents by Inventor Hashem Akhavan-Tafti

Hashem Akhavan-Tafti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200011824
    Abstract: Methods of producing luminescence by application of a time-varying electrical signal to an electroluminescent device are disclosed whereby the entire system remains at open circuit. At least one article, substance or material, the “object”, is employed to alter the electrical signal to the area of the electroluminescent device to a level sufficient to change light emission. Methods are disclosed to relate the light intensity thus produced to a property of the object thereby allowing a measurement of the property. The method may optionally use one or more additional circuit components.
    Type: Application
    Filed: April 5, 2019
    Publication date: January 9, 2020
    Inventors: Hashem AKHAVAN-TAFTI, Mojtaba AKHAVAN-TAFTI, Ali BOLANDI, Richard HANDLEY
  • Publication number: 20200011802
    Abstract: Methods and devices for the characterization of biological specimens by the use of electroluminescent materials. When placed in close proximity or direct contact to a biological specimen and an electrical signal is transmitted, electroluminescence is generated in response to the presence of the specimen. The electroluminescence produced can be in the form of an image of the specimen. The image is captured by an optical device that collects light and displays or otherwise processes the image according to the particular need or purpose. In general, the method requires preparing an electroluminescent assembly including the biological specimen, a dielectric layer, and a substrate, put together in any order. The method uses an electrical signal transmitted to the assembly. The device may be configured in a closed-circuit electrical configuration or it may be in a configuration where the EL assembly is at open circuit with respect to the power source.
    Type: Application
    Filed: August 2, 2019
    Publication date: January 9, 2020
    Inventors: Hashem AKHAVAN-TAFTI, Ali GHIASEDDIN
  • Publication number: 20200013329
    Abstract: Methods of producing luminescence by application of a time-varying electrical signal by a single wire or transmission medium to an electroluminescent device are disclosed whereby the entire system remains at open circuit. At least one substance, material or object is employed to enhance an electric field in the area of the electroluminescent device to a level sufficient to cause light emission. Methods are disclosed to relate the light intensity thus produced to a property of the electric field-enhancing substance, material or object thereby allowing a measurement of the property. The electric field-enhancing substance, material or object(s) can comprise part of the transmission medium or be placed on or near the electroluminescent device.
    Type: Application
    Filed: July 5, 2018
    Publication date: January 9, 2020
    Inventor: Hashem AKHAVAN-TAFTI
  • Patent number: 10259999
    Abstract: A method is presented for storage and on-demand release of nanoparticles. Nanoparticles produced by this method can be dried and stored for an extended period of time and subsequently released on-demand in a solvent of choice to form stable suspensions without the need for additional surfactants or stabilizers and without any loss in functionality or material properties. This method can be used to store various categories of nanomaterials including metals, metal oxides, metal chalcogenides, magnetic, polymeric and semiconductor nanoparticles.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: April 16, 2019
    Assignee: AhuraTech LLC
    Inventors: Hashem Akhavan-Tafti, Guoping Wang, Barry A. Schoenfelner
  • Patent number: 10241111
    Abstract: Methods of producing light in liquid media are provided using nanoparticles capable of generating electroluminescence when stimulated by an electrical signal. The nanoparticles are provided as a label on a target species or on a specific binding partner of the target species to be detected in a test method. The nanoparticle-labeled species are drawn into operable proximity to electrodes which, when energized by a power source, excite the nanoparticles to produce electroluminescence. Methods of performing binding assays are described using the disclosed methods.
    Type: Grant
    Filed: August 31, 2018
    Date of Patent: March 26, 2019
    Assignee: AhuraTech LLC
    Inventors: Hashem Akhavan-Tafti, Ali Ghiaseddin
  • Publication number: 20190011439
    Abstract: Methods of producing light in liquid media are provided using nanoparticles capable of generating electroluminescence when stimulated by an electrical signal. The nanoparticles are provided as a label on a target species or on a specific binding partner of the target species to be detected in a test method. The nanoparticle-labeled species are drawn into operable proximity to electrodes which, when energized by a power source, excite the nanoparticles to produce electroluminescence. Methods of performing binding assays are described using the disclosed methods.
    Type: Application
    Filed: August 31, 2018
    Publication date: January 10, 2019
    Inventors: Hashem AKHAVAN-TAFTI, Ali GHIASEDDIN
  • Patent number: 10159136
    Abstract: A method is presented for producing light using a liquid media. The method includes: hosting nanoparticles in a liquid media; disposing a pair of electrodes in direct contact with the liquid media; and generating an excitation signal between the electrodes in the pair of electrodes, thereby illuminating a portion of the nanoparticles.
    Type: Grant
    Filed: June 11, 2018
    Date of Patent: December 18, 2018
    Assignee: AhuraTech LLC
    Inventor: Hashem Akhavan-Tafti
  • Publication number: 20180295698
    Abstract: A method is presented for producing light using a liquid media. The method includes: hosting nanoparticles in a liquid media; disposing a pair of electrodes in direct contact with the liquid media; and generating an excitation signal between the electrodes in the pair of electrodes, thereby illuminating a portion of the nanoparticles.
    Type: Application
    Filed: June 11, 2018
    Publication date: October 11, 2018
    Inventor: Hashem AKHAVAN-TAFTI
  • Patent number: 10035193
    Abstract: A method is presented for synthesizing particles in the presence of a solid phase. Of note, sorption is used to associate a precursor(s) for synthesizing the particles onto or into the surface of a host structure prior to the chemical reaction that results in the particles being formed in or on surface of the host structure. Particles produced by this method can be stored for long durations and released on-demand in a solvent of choice to form stable suspensions without the need for any additional surfactants or stabilizers.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: July 31, 2018
    Assignee: AhuraTech LLC
    Inventors: Hashem Akhavan-Tafti, Guoping Wang, Barry A. Schoenfelner
  • Patent number: 10036708
    Abstract: Methods, reagents, kits and systems are disclosed for determining an analyte in a sample suspected of containing the analyte where all reagents are soluble in aqueous solution. One assay method includes treating a sample suspected of containing the analyte under conditions such that if the analyte is present, an activator is brought into reactive configuration with a chemiluminescent compound to activates it. The sample is also treated with an agent to reduce signal not related to analyte. Finally, the sample is treated with a trigger solution thereby producing light from the activated chemiluminescent compound. No reagents are associated with a surface or other solid phase.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: July 31, 2018
    Assignee: Beckman Coulter, Inc.
    Inventors: Hashem Akhavan-Tafti, Dean G. Binger, Ying Chen, Renuka De Silva, Terri McLernon, James Mendoza, Bruce H. Odegaard, Michael Salvati, Nir Shapir, Wenhua Xie
  • Patent number: 10021761
    Abstract: A method is presented for producing light using a liquid media. The method includes: hosting nanoparticles in a liquid media; disposing a pair of electrodes in direct contact with the liquid media; and generating an excitation signal between the electrodes in the pair of electrodes, thereby illuminating a portion of the nanoparticles.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: July 10, 2018
    Assignee: AhuraTech LLC
    Inventor: Hashem Akhavan-Tafti
  • Publication number: 20180132332
    Abstract: A method is presented for producing light using a liquid media. The method includes: hosting nanoparticles in a liquid media; disposing a pair of electrodes in direct contact with the liquid media; and generating an excitation signal between the electrodes in the pair of electrodes, thereby illuminating a portion of the nanoparticles.
    Type: Application
    Filed: August 21, 2017
    Publication date: May 10, 2018
    Applicants: AhuraTech LLC, AhuraTech LLC
    Inventor: Hashem Akhavan-Tafti
  • Publication number: 20180050393
    Abstract: A method is presented for synthesizing particles in the presence of a solid phase. Of note, sorption is used to associate a precursor(s) for synthesizing the particles onto or into the surface of a host structure prior to the chemical reaction that results in the particles being formed in or on surface of the host structure. Particles produced by this method can be stored for long durations and released on-demand in a solvent of choice to form stable suspensions without the need for any additional surfactants or stabilizers.
    Type: Application
    Filed: August 18, 2016
    Publication date: February 22, 2018
    Inventors: Hashem AKHAVAN-TAFTI, Guoping WANG, Barry A. SCHOENFELNER
  • Publication number: 20180051209
    Abstract: A method is presented for storage and on-demand release of nanoparticles. Nanoparticles produced by this method can be dried and stored for an extended period of time and subsequently released on-demand in a solvent of choice to form stable suspensions without the need for additional surfactants or stabilizers and without any loss in functionality or material properties. This method can be used to store various categories of nanomaterials including metals, metal oxides, metal chalcogenides, magnetic, polymeric and semiconductor nanoparticles.
    Type: Application
    Filed: August 18, 2016
    Publication date: February 22, 2018
    Inventors: Hashem AKHAVAN-TAFTI, Guoping WANG, Barry A. SCHOENFELNER
  • Patent number: 9756701
    Abstract: A method is presented for producing light using a liquid media. The method includes: suspending nanoparticles in a polar liquid media; disposing a pair of electrodes in direct contact with the liquid media; and generating an excitation signal between the electrodes in the pair of electrodes, thereby illuminating a portion of the nanoparticles.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: September 5, 2017
    Assignee: AhuraTech LLC
    Inventors: Hashem Akhavan-Tafti, Ehsan Yakhshi-Tafti, Barry A. Schoenfelner
  • Publication number: 20150212005
    Abstract: Methods, reagents, kits and systems are disclosed for determining an analyte in a sample suspected of containing the analyte where all reagents are soluble in aqueous solution. One assay method includes treating a sample suspected of containing the analyte under conditions such that if the analyte is present, an activator is brought into reactive configuration with a chemiluminescent compound to activates it. The sample is also treated with an agent to reduce signal not related to analyte. Finally, the sample is treated with a trigger solution thereby producing light from the activated chemiluminescent compound. No reagents are associated with a surface or other solid phase.
    Type: Application
    Filed: April 2, 2015
    Publication date: July 30, 2015
    Inventors: Hashem Akhavan-Tafti, Dean G. Binger, Ying Chen, Renuka De Silva, Terri McLernon, James Mendoza, Bruce H. Odegaard, Michael Salvati, Nir Shapir, Wenhua Xie
  • Patent number: 9029092
    Abstract: Methods, reagents, kits and systems are disclosed for determining an analyte in a sample suspected of containing the analyte where all reagents are soluble in aqueous solution. One assay method includes treating a sample suspected of containing the analyte under conditions such that if the analyte is present, an activator is brought into reactive configuration with a chemiluminescent compound to activates it. The sample is also treated with an agent to reduce signal not related to analyte. Finally, the sample is treated with a trigger solution thereby producing light from the activated chemiluminescent compound. No reagents are associated with a surface or other solid phase.
    Type: Grant
    Filed: February 26, 2010
    Date of Patent: May 12, 2015
    Assignee: Beckman Coulter, Inc.
    Inventors: Hashem Akhavan-Tafti, Dean G. Binger, Ying Chen, Renuka De Silva, Terri McLernon, James Mendoza, Bruce H. Odegaard, Michael Salvati, Nir Shapir, Wenhua Xie
  • Patent number: 8772501
    Abstract: The present invention provides fluorescent dyes that are based on firefly luciferin structure. These dyes are optimally excited at shorter wavelengths and have Stokes shift of at least 50 nm. The fluorescent dyes of the invention are useful for preparation of dye-conjugates, which can be used in detection of an analyte in a sample.
    Type: Grant
    Filed: January 24, 2013
    Date of Patent: July 8, 2014
    Assignee: Beckman Coulter, Inc.
    Inventors: Hashem Akhavan-Tafti, Renuka De Silva, Guoping Wang, Robert A. Eickholt, Ravinder Gupta, Lakshmi S. Kaanumalle
  • Publication number: 20130084652
    Abstract: Methods are disclosed for determining an analyte in a medium suspected of containing the analyte. One method comprises treating a medium suspected of containing an analyte under conditions such that the analyte, if present, causes a photosensitizer and a chemiluminescent compound to come into close proximity. The photosensitizer generates singlet oxygen and activates the chemiluminescent compound when it is in close proximity. Non-specific signal generated by singlet oxygen not in proximity is reduced or suppressed using a singlet oxygen quencher (SOQ). The activated chemiluminescent compound subsequently produces light. The amount of light produced is related to the amount of analyte in the medium. Use of Noise Modulation Agents significantly improves signal-to-noise ratios and assay sensitivity. Compositions and kits are also disclosed.
    Type: Application
    Filed: May 13, 2011
    Publication date: April 4, 2013
    Applicant: BECKMAN COULTER, INC.
    Inventors: Nir Shapir, Michael Salvati, Jeff Todtleben, Hashem Akhavan-Tafti, Richard S. Handley
  • Patent number: 8389298
    Abstract: Methods using chemiluminescent label compounds and chemiluminescent labeled conjugates are provided. The compounds comprise an acridan ring bearing an exocyclic ketene dithioacetal group and further contain a labeling substituent which permits attachment to compounds of interest. The novel chemiluminescent compounds and labeled conjugates are convenient to prepare, are highly stable, and generate chemiluminescence rapidly on demand. The compounds and conjugates are useful in assays of an analyte in a sample and in assays employing labeled specific binding pairs.
    Type: Grant
    Filed: March 19, 2010
    Date of Patent: March 5, 2013
    Assignee: Lumigen, Inc.
    Inventors: Hashem Akhavan-Tafti, Renuka De Silva, Wenhua Xie