Patents by Inventor Hatim T. Allawi

Hatim T. Allawi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11859254
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as gastric cancer.
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: January 2, 2024
    Assignees: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, Exact Sciences Corporation
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney, Hatim T. Allawi
  • Publication number: 20230416840
    Abstract: Provided herein is technology for prostate cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of prostate cancer.
    Type: Application
    Filed: May 24, 2023
    Publication date: December 28, 2023
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney, Brian A. Dukek, Matthew T. Gettman, Hatim T. Allawi
  • Patent number: 11821039
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer.
    Type: Grant
    Filed: May 12, 2020
    Date of Patent: November 21, 2023
    Assignees: Mayo Foundation for Medical Education and Research, Exact Sciences Corporation
    Inventors: David A. Ahlquist, John B. Kisiel, William R. Taylor, Tracy C. Yab, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi
  • Publication number: 20230357852
    Abstract: Provided herein is technology for cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of non-Hodgkin lymphoma (NHL) and NHL subtypes (e.g., diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, mantle cell lymphoma, marginal zone lymphoma, peripheral T-cell lymphoma).
    Type: Application
    Filed: August 18, 2021
    Publication date: November 9, 2023
    Inventors: John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist, William R. Taylor, Hatim T. Allawi, Viatcheslav E. Katerov
  • Patent number: 11746384
    Abstract: Provided herein is technology relating compositions and methods for detecting tissue cell-specific DNA, such as epithelial cell-specific DNA, in blood or blood products from a subject. The technology also relates to use of tissue cell-specific DNAs as internal controls for methylation assays.
    Type: Grant
    Filed: October 28, 2019
    Date of Patent: September 5, 2023
    Assignee: EXACT SCIENCES CORPORATION
    Inventors: Hatim T. Allawi, Graham P. Lidgard
  • Patent number: 11702704
    Abstract: Provided herein is technology for ovarian cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of ovarian cancer and sub-types of ovarian cancer (e.g., clear cell ovarian cancer, endometrioid ovarian cancer, mucinous ovarian cancer, serous ovarian cancer).
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: July 18, 2023
    Assignees: Mayo Foundation for Medical Education and Research, Exact Sciences Corporation
    Inventors: William R. Taylor, John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist, Hatim T. Allawi, Michael W. Kaiser
  • Patent number: 11697853
    Abstract: Provided herein is technology for prostate cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of prostate cancer.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: July 11, 2023
    Assignees: Mayo Foundation for Medical Education and Research, Exact Sciences Corporation
    Inventors: David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney, Brian A. Dukek, Matthew T. Gettman, Hatim T. Allawi
  • Publication number: 20230190243
    Abstract: The invention relates to cell sampling devices. In particular, the present invention relates to ingestible cell sampling devices for sampling cells in a subject, and methods of use for detecting abnormalities in a subject using the same.
    Type: Application
    Filed: April 16, 2021
    Publication date: June 22, 2023
    Inventors: Robert F. Eisele, Michael E. Williams, Prasad G. Iyer, Paul Marrione, Hatim T. Allawi, Graham P. Lidgard, Maria Giakoumopoulos, William R. Taylor, Tracy C. Yab, Douglas W. Mahoney, John B. Kisiel, David A. Ahlquist
  • Publication number: 20230151433
    Abstract: Provided herein is technology for primary cutaneous melanoma screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of primary cutaneous melanoma.
    Type: Application
    Filed: May 4, 2021
    Publication date: May 18, 2023
    Inventors: David A. Ahlquist, John B. Kisiel, William R. Taylor, Douglas W. Mahoney, Calise K. Berger, Hatim T. Allawi, Viatcheslav Katerov
  • Publication number: 20220403471
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting neoplasms such as lung cancer.
    Type: Application
    Filed: August 27, 2020
    Publication date: December 22, 2022
    Inventors: Scott Morris, David Mallery, Hatim T. Allawi, Graham P. Lidgard, Maria Giakoumopoulos, Michael W. Kaiser, David A. Ahlquist, William R. Taylor, Douglas W. Mahoney
  • Publication number: 20220349009
    Abstract: Provided herein is technology for screening for esophageal disorders, including but not limited to, Barrett's esophagus (BE). In particular, provided herein are methods, compositions, and related uses for detecting the presence or absence of esophageal disorders from a biological sample.
    Type: Application
    Filed: April 22, 2022
    Publication date: November 3, 2022
    Inventors: William R. Taylor, Tracy C. Yab, Douglas W. Mahoney, John B. Kisiel, David A. Ahlquist, Hatim T. Allawi, Graham P. Lidgard, Maria Giakoumopoulos
  • Publication number: 20220340959
    Abstract: Provided herein is technology relating compositions and methods for analysis of methylated DNA from a subject. The technology also relates to use of endogenous methylated DNAs as internal controls for marker gene methylation assays.
    Type: Application
    Filed: May 10, 2022
    Publication date: October 27, 2022
    Inventors: Hatim T. Allawi, Graham P. Lidgard
  • Publication number: 20220243278
    Abstract: Provided herein is technology for screening multiple types of cancer from a biological sample, and particularly, but not exclusively, to methods, compositions, and related uses for simultaneously detecting the presence of multiple types of cancer (e.g., liver cancer, esophageal cancer, lung cancer, ovarian cancer, pancreatic cancer, gastric cancer, bladder cancer, breast cancer, cervical cancer, colorectal cancer, prostate cancer, renal cancer, and uterine cancer) from a biological sample (e.g., stool sample, tissue sample, organ secretion sample, CSF sample, saliva sample, blood sample, plasma sample or urine sample).
    Type: Application
    Filed: January 28, 2022
    Publication date: August 4, 2022
    Inventors: William R. Taylor, Hatim T. Allawi, Viatcheslav E. Katerov, John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist
  • Patent number: 11365451
    Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: June 21, 2022
    Assignees: Mayo Foundation for Medical Education and Research, Exact Sciences Corporation
    Inventors: David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi
  • Patent number: 11345949
    Abstract: Provided herein is technology relating compositions and methods for analysis of methylated DNA from a subject. The technology also relates to use of endogenous methylated DNAs as internal controls for marker gene methylation assays.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: May 31, 2022
    Assignee: Exact Sciences Corporation
    Inventors: Hatim T. Allawi, Graham P. Lidgard
  • Publication number: 20220162709
    Abstract: Provided herein is technology for pancreatic ductal adenocarcinoma (PDAC) screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of PDAC.
    Type: Application
    Filed: April 3, 2020
    Publication date: May 26, 2022
    Inventors: William R. Taylor, John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist, Hatim T. Allawi
  • Publication number: 20220136035
    Abstract: The present invention provides synthetic DNA strands that find use as process controls in DNA processing and nucleic acid testing methods. In particular, provided herein are synthetic methylated DNA strands of known composition for use as control molecules in DNA testing, e.g., of mutations and/or methylation of DNA isolated from non-fish samples, such as human samples.
    Type: Application
    Filed: November 18, 2021
    Publication date: May 5, 2022
    Inventors: Hatim T. Allawi, Graham P. Lidgard, Brian Aizenstein, Melissa M. Gray
  • Publication number: 20220119862
    Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
    Type: Application
    Filed: November 5, 2021
    Publication date: April 21, 2022
    Inventors: Hatim T. Allawi, William G. Weisburg, Graham P. Lidgard, Michael W. Kaiser, Abram M. Vaccaro, Gracie Shea
  • Publication number: 20220106644
    Abstract: Provided herein is technology for endometrial cancer (EC) screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of endometrial cancer and various subtypes of endometrial cancer.
    Type: Application
    Filed: January 24, 2020
    Publication date: April 7, 2022
    Inventors: William R. Taylor, John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist, Hatim T. Allawi, Maria Giakoumopoulos
  • Publication number: 20220071605
    Abstract: The invention relates to cell sampling devices. In particular, the present invention relates to ingestible cell sampling devices for sampling cells in a subject, and methods of use for detecting abnormalities in a subject using the same. Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer.
    Type: Application
    Filed: April 16, 2021
    Publication date: March 10, 2022
    Inventors: Robert F. Eisele, Michael E. Williams, Prasad G. Iyer, Paul Marrione, Hatim T. Allawi, Graham P. Lidgard, Maria Giakoumopoulos, William R. Taylor, Tracy C. Yab, Douglas W. Mahoney, John B. Kisiel, David A. Ahlquist