Abstract: Provided is a sulfonamide derivate represented by the general formula (I), a preparation method thereof, a pharmaceutical composition containing said derivative, and the use thereof as a therapeutic agent, especially as a Lysine Acetyl Transferase (KAT) inhibitor and the use of same in the preparation of a medicament for the treatment and/or prevention of cancer.

Abstract: An integrated development environment (IDE) for uses a generative artificial intelligence (AI) model to generate industrial control code in accordance with functional requirements provided to the industrial IDE system as natural language prompts. The system's generative AI model leverages both a code repository storing sample control code and a document repository that stores device or software manuals, program instruction manuals, functional specification documents, or other technical documents. These repositories are synchronized by digitizing selected portions of document text from the document repository into control code for storage in the code repository, as well as contextualizing control code from the code repository into text-based documentation for storage in the document repository.

Abstract: Provided are a fused bicyclic derivative, a pharmaceutically acceptable salt, a crystal form thereof and a preparation method therefor. Specifically, provided are a hydrochloride, a mesylate, an acetate and a tartrate of the compound of formula (I), and a preparation method therefor and a crystal form thereof.

Abstract: An X-ray measurement system with high signal resolution is provided. The X-ray measurement system includes an X-ray generator, an X-ray optical element group, a multi-dimensional X-ray detector and a processing device. The X-ray generator is configured to generate an incident X-ray beam. X-ray optics are used to guide the incident X-ray beam to a to-be-tested sample. The multi-dimensional X-ray detector is used to receive the measurement X-ray generated by irradiating the incident X-ray beam on the to-be-tested sample. The multi-dimensional X-ray detector includes an insulation layer, a plurality of first electrode layers, a photodiode layer, an X-ray conversion material layer made of amorphous selenium, and a second electrode layer. The processing device is configured to collect a to-be-tested X-ray signal and generate a plurality of measurement results that include a plurality of mode signals of different orders.

Abstract: A new class of weakly coordinating anions (WCA) based on silicates is disclosed. Facile tuning of sterics and solubility of the disclosed WCA may be achieved via variation of R groups. The anions support a range of cations employed in chemical reactivity, including ether-free alkali cations, Ag+, Ph3C+, Fc+, [NiI(COD)2]+. In one aspect, [Pd(dppe)(NCMe)Me]+ may be generated by salt metathesis or protonation of a metal-alkyl bond, showcasing the ability of the anions to support applications in coordination chemistry and catalysis. Electrochemical studies on the [Bu4N]+ variant show an exceptionally wide stability window for the MeSiF24? anion of 7.5 V in MeCN. CV experiments demonstrate reversible Mg deposition and stripping.

Abstract: An anode material, a preparation method thereof, and a battery provided. The anode material includes a secondary particle, the secondary particle includes a plurality of agglomerated primary particles, and a primary particle of the plurality of primary particles includes an active material doped with iron element and nickel element, where the iron element accounts for a mass content of A ppm in the anode material, the nickel element accounts for a mass content of B ppm in the anode material, and 9.2?A/B?20. In the anode material provided, hardness of the nano-silicon is strengthened, thereby improving stability of the nano-silicon particles, reducing volume change of the anode material, and improving cycling stability of the battery.

Abstract: This invention pertains to the field of plant extraction and separation technology and provides a polysaccharide compound, GLP-4, with a defined molecular structure, effective in treating emphysema and pulmonary fibrosis, and exhibiting antitumor effects. The molecular formula is: (C162H270O135)n. The polysaccharide compound is obtained by extracting from a residue of Ganoderma lucidum processed with alkaline solution under high temperature and high pressure, followed by column chromatographic separation. The polysaccharide compound features excellent water solubility and is readily absorbed by the human body. The polysaccharide compound shows superior efficacy in treating emphysema and pulmonary fibrosis compared to pirfenidone and is also effective for patients with advanced cancer (those who are no longer surgical candidates, with a life expectancy of only three to six months, and still eligible for chemotherapy).

Abstract: An off-road vehicle includes a frame; front and rear wheels; a front suspension assembly; a front torsion bar assembly, a rear suspension assembly and a rear torsion bar assembly. The front suspension assembly comprises a front lower rocker arm, a front upper rocker arm, and a front wheel shaft support assembly mounted between the front lower and the front upper rocker arms. The front torsion bar assembly is located above the front upper rocker arm, and is movably connected to the front upper rocker arm. The rear suspension assembly comprises a rear lower rocker arm, a rear upper rocker arm, a control arm assembly, and a rear wheel shaft support assembly mounted between the rear lower and rear upper rocker arms. The rear torsion bar assembly is located between the rear upper and lower rocker arms, and is movably connected to the rear upper rocker arm.

Abstract: The present disclosure relates to an in-plane two-dimensional translational optical actuator. The in-plane two-dimensional translational optical actuator includes a fixed plate, a translational plate, i elastic assemblies located between the fixed plate and the translational plate and with two ends connected to the fixed plate and the translational plate respectively, and j electromagnetic drive assemblies fixed between the fixed plate and the translational plate. Each elastic assembly is composed of elastic elements of the same or different quantities, and at least one elastic assembly in the i elastic assemblies has two or more elastic elements. The j electromagnetic drive assemblies are disposed in a plane in two different directions, and used to drive the translational plate to move relative to the fixed plate within a plane where the translational plate is located in two different directions, so as to achieve two-dimensional translation of the translational plate.

Abstract: A wave-resistant photovoltaic float used in a water environment, which includes multiple photovoltaic carriers and a photovoltaic module. The photovoltaic carrier includes an upper component and a lower component, which are integrally formed. The upper component is smaller than the lower component in terms of length and width. The lower component of the photovoltaic carrier is a flat-shaped floating structure. A hollow portion is provided in the middle of the lower component, and acts as a suction cup.

Abstract: A method for predicting a structure of a protein complex includes: obtaining an initial coordinate of each amino acid residue in a target protein complex, and obtaining a target residue pair feature, a first multiple sequence alignment (MSA) feature and a second MSA feature of each protein monomer in the target protein complex; and inputting the initial coordinate of each amino acid residue, and the target residue pair feature, the first MSA feature and the second MSA feature of each protein monomer into an N-level fold iteration network layer, and obtaining a target coordinate of each amino acid residue by predicting a torsion angle, a position transformation at residue level and a position transformation at monomer chain level of each amino acid residue via the N level fold iteration network layer, to obtain a predicted structure of the protein complex.

Abstract: A user equipment including a transceiver and a processor is disclosed. The processor is configured to determine a sidelink control information (SCI) format payload size based on resource pool configuration for the UE for inter-UE coordination with a second UE. The processor is configured to determine, based on the determined SCI format payload size, an SCI format including a number of message elements identifying attributes of a number of resources being used by the UE over a predetermined time period. The processor is configured to encode and transmit, to the second UE, the SCI format for the IUC for resource selection by the second UE.

Abstract: The present application provides a command configuration method, a command configuration unit, a display processor unit, and an electronic device and relates to the field of data transmission. The command configuration unit comprises: a readable data channel including a buffer and a selector, the buffer being configured with a plurality of buffer regions; and a plurality of command interfaces, each of the command interfaces being configured to correspond to a different one of the buffer regions, respectively. Each of the command interfaces is configured to be connected to the image processing module. The selector is configured to receive the readable data and store the readable data in a corresponding buffer region according to the identification information. Each of the command interfaces is configured to acquire the readable data from the corresponding buffer region and configure the image processing module based on the configuration command in the readable data.

Abstract: A method includes selecting one or more candidate installation positions in a bottom area below a central horizontal line of the refrigerant heat exchanger, determining one or more highest risk leakage points each corresponding to one of the one or more candidate installation positions and reflecting a refrigerant leakage position in the refrigerant heat exchanger with a lowest probability of being detected by the refrigerant sensor installed at the corresponding candidate installation position, calculating one or more leakage limit distances each corresponding to one of the one or more highest risk leakage points, determining a target highest risk leakage point corresponding to a target leakage limit distance that is a smallest one of the one or more leakage limit distances, determining a target installation position based at least on the target highest risk leakage point, and installing the refrigerant sensor at the target installation position.

Abstract: A scalpel includes a blade and a handle, where the blade includes an outer blade, an inner blade, and a sheath. A distal end of the outer blade and a distal end of the inner blade are sequentially arranged from a distal end to a proximal end of the blade. The outer blade, the inner blade and the sheath are coaxial. The inner blade and the outer blade are configured to be capable of moving relatively in an axial direction or rotating relatively around a central axis. The inner blade includes an electrode. The electrode is connected to a radiofrequency generation apparatus. The electrode covers a cross-section of the distal end of the inner blade or covers a non-radial cross-sectional groove edge of an inner blade groove. The interior of the inner blade or an inner channel of the inner blade can be connected to a negative pressure apparatus.

Abstract: Improved method and apparatus for signaling of reference pictures used for temporal prediction. The signaling schemes and construction process for different reference picture lists in HEVC Working Draft 5 (WD5) are improved.

Abstract: The present application relates to an anode material and a lithium-ion battery. The anode material includes an active material including a porous matrix and a silicon matrix. At least a portion of the silicon matrix is distributed in pores of the porous matrix. In the infrared spectrum obtained by testing the anode material using an infrared spectrometer, there are a stretching vibration peak of SiH2 bond at a wave number of 2090 cm?1 and a stretching vibration peak of SiH bond at a wave number of 2000 cm?1. A ratio Z of an area of the stretching vibration peak of the SiH2 bond to an area of the stretching vibration peak of the SiH bond is in a range from 0.01 to 5.0. Within the above defined range, it indicates that the silicon matrix in the anode material mainly exists in the form of SiH bonds.

Abstract: Provided are anode material and battery. The anode material includes a carbon material and silicon material. The anode material has pores. An average shape coefficient of the anode material is F0, and 0.65?F0<1. The average shape coefficient F0 of the anode material is obtained through the following manners: ten anode material particles are randomly acquired, a cross-sectional area Sn and a circumference Cn of each anode material particle are measured, Fn=4*?*Sn/Cn2, where n is selected from natural numbers from 1 to 10, an average value of shape coefficients Fn of the 10 particles is calculated, and the average value is recorded as the average shape coefficient F0 of the anode material.

Abstract: Computer implemented method for converting PDF documents into human readable and machine parsable HTML code. The method includes the use of a machine learning algorithm in order to automatically annotate the HTML code, said algorithm being trained with a set of manually annotated HTML code examples.

Abstract: Provided are material and preparation method thereof, and battery. The anode material includes an active substance. Surface compactness of the anode material is ?, and ??80%. ? is measured by the following test methods: the anode material with mass of m1 g is soaked in a hydrofluoric acid solution with a mass fraction of 20% for 1 hour, then washed and dried to obtain m2 g of a material, and the surface compactness of the anode material is obtained through calculated, where ?=m2/m1×100%.