Patents by Inventor Hee-sung Park
Hee-sung Park has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250060275Abstract: A shock fatigue testing device for a powertrain mount includes: a main frame having a guide support vertically extending from a base plate and a mounting plate coupled to the guide support; a first mount jig mounted to the mounting plate and configured to support the upper portion of a mount member; a second mount jig mounted to a lower portion of the mount member and configured to support the lower portion of the mount member; a weight portion fixed to the second mount jig and configured to apply a load to the mount member; and a vibration portion configured to continuously provide vibration to the base plate to vibrate the weight portion using the main frame, the first mount jig, and the second mount jig as media.Type: ApplicationFiled: January 11, 2024Publication date: February 20, 2025Applicants: HYUNDAI MOTOR COMPANY, KIA CORPORATIONInventors: Woon Ki Cho, Jung Ho Park, Jong Hwan Jang, Ji Hyeon Lee, Hee Sung Lee, Moon Joon Kim, Soon Ju Kim, Jin Young Lee
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Publication number: 20250062883Abstract: Provided is a method for processing a physical resource block in a wireless communication system. The method includes identifying, by a distributed unit, user equipment (UE) connected to each of a plurality of radio units (RUs) and acquiring connection information, generating, by the distributed unit, physical resource block allocation information on a resource block area allocated to each of the plurality of RUs based on the connection information, distributing, by a fronthaul multiplexer (FHM), the resource block area allocated to each of the plurality of RUs based on the physical resource block allocation information, and transmitting, by each of the plurality of RUs, a radio signal to at least one UE based on the distributed physical resource block area.Type: ApplicationFiled: November 7, 2024Publication date: February 20, 2025Applicant: HFR, INC.Inventors: Jai Seo PARK, Hee Sung SHIN, Kyong Mo MIN
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Publication number: 20240384213Abstract: A bioreactor for suspension cells is provided. The bioreactor for suspension cells may comprise: a frame unit; a driving unit mounted on the frame unit, and a cell culture unit including a housing having an inner space filled with a medium containing suspension cells, and a plurality of supports disposed in multiple stages in the inner space to be spaced at intervals from each other, the cell culture unit having one end axially coupled to the driving unit.Type: ApplicationFiled: September 15, 2022Publication date: November 21, 2024Applicant: AMOGREENTECH CO., LTD.Inventors: Seon Ho JANG, Kyoung Ku HAN, In Yong SEO, Seoung Hoon LEE, Jae Kyung SONG, Song Hee KOO, Hee Sung PARK, Hyeong Tak NOH, Ji Young KIM, Su Yeon LEE, Seung Min CHO
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Publication number: 20230303957Abstract: A cell culture device is provided. A cell culture device according to an exemplary embodiment of the present invention includes: a body including a culture space having an upper surface and lower surface that are open; a planar culture plate that is fixed to the body so as to cover the open lower surface of the culture space and forms a culture surface on which cells are cultured, the surface forming the culture surface being modified to allow the cells to easily attach to the culture surface; and a cover member that is fixed to the body so as to cover the open upper surface of the culture space.Type: ApplicationFiled: June 9, 2021Publication date: September 28, 2023Inventors: Kyoung Ku HAN, Seon Ho JANG, Jae Kyung Song, Hee Sung PARK
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Publication number: 20230227761Abstract: A cell culture device is provided. A cell culture device according to an exemplary embodiment of the present invention includes: a main body comprising a culture space having one surface that is open; and a surface-modified sheet-type culture plate which is fixed to the main body to cover the opened one surface of the culture space, and thus forms a culture surface on which cells are cultured, and which forms the culture surface so that the cells can be attached to the culture surface.Type: ApplicationFiled: June 9, 2021Publication date: July 20, 2023Inventors: Kyoung Ku HAN, Seon Ho JANG, Jae Kyung Song, Hee Sung PARK
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Publication number: 20230174910Abstract: A cell culture device is provided. The cell culture device according to an exemplary embodiment of the present invention comprises: a body which includes a plurality of culture spaces formed therethrough in the height direction; and a plate-shaped cover member which is fixed to the bottom surface of the body while covering the open bottom portions of the culture spaces to thus form a culture surface where cells are cultured, and is surface-modified so as to allow the cells to be effectively attached to the culture surface.Type: ApplicationFiled: May 28, 2021Publication date: June 8, 2023Applicant: AMOGREENTECH CO., LTD.Inventors: Kyoung Ku HAN, Seon Ho JANG, Jae Kyung SONG, Hee Sung PARK
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Publication number: 20230080853Abstract: A method for manufacturing a fiber assembly for providing a binding surface to a bio-substance is provided. A fiber assembly for providing a binding surface to a bio-substance according to an embodiment of the present invention is manufactured by a method comprising the steps of: (1) preparing a fiber assembly in which a plurality of fibers is accumulated; and (2) performing modification to provide the fiber surface with a carboxyl group reactive to an amine group present in a bio-substance. According to the method, a bio-substance can be easily introduced at a high content into the fiber assembly. In addition, bio-substances that are conjugated therebetween and adsorbed through physical adsorption, etc. are remarkably reduced in the introduction procedure of bio-substances, whereby bio-substances can be availed with high precision and reliability in applications employing bio-substances.Type: ApplicationFiled: February 17, 2021Publication date: March 16, 2023Applicant: AMOGREENTECH CO., LTD.Inventors: SeonHo JANG, Hee Sung PARK, Sung Il KIM, Seam MUN, Song Hee KOO, Su Yeon LEE, Ji Young KIM, In Yong SEO, Seoung Hoon LEE, Chan KIM
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Publication number: 20220389362Abstract: A cell culture apparatus is provided. A cell culture apparatus according to one exemplary embodiment of the present invention comprises: a cell culture part comprising an accommodation space in which a plurality of supports for cell culture are disposed; a medium supply part for storing a predetermined amount of medium to be supplied to the cell culture part, and maintaining a predetermined carbon dioxide concentration of the medium stored therein by using carbon dioxide introduced from the outside through a gas supply port; and a pump, which interconnects the cell culture part and the medium supply part so as to circulate, in the cell culture part, a medium stored in the medium supply part.Type: ApplicationFiled: October 12, 2020Publication date: December 8, 2022Inventors: Hee Sung PARK, In Yong SEO, Seoung Hoon LEE, Seon Ho JANG, Su Yeon LEE, Ji Young KIM, Hyo Jung LEE
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Publication number: 20220389360Abstract: A cell culture device is provided. A cell culture device according to an exemplary embodiment of the present invention comprises: a housing which has a plurality of through-holes formed through at least one surface thereof to allow carbon dioxide to be introduced thereinto from the outside and includes an inner space filled with a medium for culturing cells; a plurality of supporters which are arranged in the inner space in multiple steps while being spaced at an interval from each other so as to culture cells and are provided in a plate-shape having a predetermined area; and a porous member which is attached to one surface of the housing so as to cover the plurality of through-holes, prevents the medium filled in the inner space from leaking to the outside, and allows carbon dioxide to be introduced into the inner space from the outside.Type: ApplicationFiled: October 12, 2020Publication date: December 8, 2022Inventors: Hee Sung PARK, In Yong SEO, Seoung Hoon LEE, Kyung Gu HAN, Seon Ho JANG, Jae Yun KIM, Su Yeon LEE, Ji Young KIM, Hyo Jung LEE
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Publication number: 20220340852Abstract: Provided is a cell culture sheet. A cell culture sheet according to an embodiment of the present invention includes: a fiber web which has a 3-dimensional network structure formed through the accumulation of support fibers having an average diameter of at most 1.5 ?m, and has a basis weight of 1 to 15 g/m2; and a functional coating layer which is coated on the support fibers exposed on at least one surface of the fiber web, and has a function of promoting one or more of the adhesion, movement, proliferation, and differentiation of cells. Accordingly, cell adhesion is improved due to the large specific surface area and the surface morphology suitable for cells, and the adhered cells are stably supported. Moreover, the cells can be cultured at high density at a high culture efficiency, and can be cultured and recovered without agglomeration caused by forming a thin film.Type: ApplicationFiled: September 7, 2020Publication date: October 27, 2022Applicant: AMOLIFESCIENCE CO., LTD.Inventors: Seon Ho JANG, In Yong SEO, Kyoung Ku HAN, Dong Sik SEO, Hee Sung PARK, Su Yeon LEE, Hyo Jung LEE, Ji Young KIM, Chan KIM, Seoung Hoon LEE
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Publication number: 20220002654Abstract: A large-scale cell culture system is provided.Type: ApplicationFiled: November 14, 2019Publication date: January 6, 2022Applicant: AMOGREENTECH CO., LTD.Inventors: Seon Ho JANG, Kyung Gu HAN, In Yong SEO, Dong Sik SEO, Hee Sung PARK
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Publication number: 20220002651Abstract: Provided is a cell culture sheet for a large-capacity incubator. A cell culture sheet according to one embodiment of the present invention is a cell culture sheet provided in a large-capacity incubator having a plurality of sheets disposed to be spaced apart at predetermined intervals therein, wherein the cell culture sheet has an area of 100 cm2 or more and a bending depth of 0.5 cm or less. As such, even when the culture sheets are closely placed in a limited volume of space, there is little sagging or shape deformation in a specific direction to prevent the occurrence of contact with adjacent culture sheets, thereby preventing a decrease in cell culture volume due to a dead space. Furthermore, since the flow of a cell culture fluid due to the occurrence of contact can be minimized or prevented, a large capacity of cells can be stably and smoothly cultivated such that the cell culture sheet is very suitable for a large-capacity incubator and can be widely applied to the cell culture industry.Type: ApplicationFiled: November 14, 2019Publication date: January 6, 2022Applicant: AMOGREENTECH CO., LTD.Inventors: Seon Ho JANG, Hee Sung PARK, Kyung Gu HAN, Dong Sik SEO, Song Hee KOO, Ji Young KIM, Hyo Jung LEE, Su Yeon LEE, In Yong SEO, Seoung Hoon LEE, Chan KIM
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Patent number: 11123402Abstract: An anticancer composition includes cervical cancer-derived autocrine motility factor (AMF) as an effective component. The cervical cancer-derived AMF has an excellent effect of inhibiting the proliferation of liver cancer, pancreatic cancer, breast cancer, lung cancer, prostate cancer, and colon cancer, and inducing cell death. The composition can be used as an anticancer therapeutic agent.Type: GrantFiled: June 4, 2018Date of Patent: September 21, 2021Assignee: DAEGU CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATIONInventor: Hee Sung Park
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Publication number: 20210275631Abstract: An anticancer composition includes cervical cancer-derived autocrine motility factor (AMF) as an effective component. The cervical cancer-derived AMF has an excellent effect of inhibiting the proliferation of liver cancer, pancreatic cancer, breast cancer, lung cancer, prostate cancer, and colon cancer, and inducing cell death. The composition can be used as an anticancer therapeutic agent.Type: ApplicationFiled: June 4, 2018Publication date: September 9, 2021Inventor: Hee Sung PARK
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Patent number: 10905107Abstract: The present invention relates to a mouse (Mus musculus) in which expression and site-specific modification of a target protein is temporally and spatially controlled, and a method for producing the same and the use thereof, and more particularly to a transgenic mouse in which expression of a target protein having a modification attached to a specific position is temporally and spatially controlled as a result of incorporation of an unnatural amino acid. In the mouse according to the present invention, in which site-specific modification of a target protein is temporally and spatially controllable, expression of the target protein having the site-specific modification attached thereto is controllable depending on the timing and/or position of introduction of an unnatural amino acid. Thus, the mouse according to the present invention is useful for studies on the in vivo functions of cellular proteins, various human diseases including cancers and neurodegenerative disorders, new drug discovery, and the like.Type: GrantFiled: September 5, 2017Date of Patent: February 2, 2021Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Hee-Sung Park, Aerin Yang
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Publication number: 20200385742Abstract: Nucleic acids encoding mutant elongation factor proteins (EF-Sep), phosphoseryl-tRNA synthetase (SepRS), and phosphoseryl-tRNA (tRNASep) and methods of use in site specific incorporation of phosphoserine into & protein or polypeptide are described. Typically, SepRS preferentially aminoacylates tRNASepwith O-phosphoserine and the tRNASep recognizes at least one codon such as a stop codon. Due to the negative charge of the phosphoserine, Sep-tRNASep does not bind elongation factor Tu (EF-Tu). However, mutant EF-Sep proteins are disclosed that bind Sep-tRNASep and protect Sep-tRNASep from deacylation. In a preferred embodiment the nucleic acids are on vectors and are expressed in cells such as bacterial cells, archeaebacterial cells, and eukaryotic cells.Type: ApplicationFiled: January 17, 2020Publication date: December 10, 2020Inventors: Hee-Sung Park, Dieter Soll
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Patent number: 10723760Abstract: A method for producing a site-specifically modified protein based on new carbon-carbon bond formation is disclosed, including the following three steps (marking, activation, and coupling steps): (a) marking of the modification site by incorporating a specific amino acid into a selected position of a target protein; (b) activation of the marked site; and (c) coupling of various post-translational modification (PTM) moieties or other chemical groups onto the activated site to obtain a site-specifically modified protein. The method for producing a site-specifically modified protein can incorporate desired diverse chemical groups including post-translational modification (PTM) moieties into a designated site in a target protein through a new carbon-carbon bond. Furthermore, the modified protein having a site-specific PTM exhibits the same chemical and functional properties as that of a target protein present in cells.Type: GrantFiled: August 31, 2017Date of Patent: July 28, 2020Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Hee-Sung Park, Hee-Yoon Lee, Aerin Yang, Sura Ha
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Patent number: 10678420Abstract: Disclosed is an electronic device. The present electronic device comprises a display, and a processor configured to display, through the display, a UI based on use patterns of a plurality of devices connected to a same network, wherein the UI comprises a device axis and a time axis, and provides information related to use of at least one device in a region where the device axis and the time axis intersect each other.Type: GrantFiled: September 21, 2016Date of Patent: June 9, 2020Assignee: Samsung Electronics Co., LtdInventors: Yu-ri Choi, Hee-sung Park, Se-rin Ko, Dong-seok Kim, Jeong-pyo Lee, Seung-hyun Cho
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Patent number: 10538773Abstract: Nucleic acids encoding mutant elongation factor proteins (EF-Sep), phosphoseryl-tRNA synthetase (SepRS), and phosphoseryl-tRNA (tRNASep) and methods of use in site specific incorporation of phosphoserine into a protein or polypeptide are described. Mutant EF-Sep proteins are disclosed that bind Sep-tRNASep and protect Sep-tRNASep from deacylation. In a preferred embodiment the nucleic acids are on vectors and are expressed in cells such as bacterial cells, archeaebacterial cells, and eukaryotic cells. Proteins or polypeptides containing phosphoserine produced by the methods described herein can be used for a variety of applications such as research, antibody production, protein array manufacture and development of cell-based screens for new drug discovery.Type: GrantFiled: February 22, 2017Date of Patent: January 21, 2020Assignee: Yale UniversityInventors: Hee-Sung Park, Dieter Soll
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Publication number: 20180292962Abstract: Disclosed is an electronic device. The present electronic device comprises a display, and a processor configured to display, through the display, a UI based on use patterns of a plurality of devices connected to a same network, wherein the UI comprises a device axis and a time axis, and provides information related to use of at least one device in a region where the device axis and the time axis intersect each other.Type: ApplicationFiled: September 21, 2016Publication date: October 11, 2018Inventors: Yu-ri CHOI, Hee-sung PARK, Se-rin KO, Dong-seok KIM, Jeong-pyo LEE, Seung-hyun CHO