Patents by Inventor Heike Heckroth

Heike Heckroth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230227600
    Abstract: The present invention relates to polyphosphazenes, polyurethanes based on these polyphosphazenes, methods for their manufacture and hydrogels based on the polyurethanes. The invention further relates to the use of the hydrogels in medical, veterinary and agricultural applications. The terminal ends of the polyphosphazenes bear NCO-reactive hydrogen atoms for reaction with polyisocyanates.
    Type: Application
    Filed: June 21, 2021
    Publication date: July 20, 2023
    Inventors: Heike Heckroth, Frank Richter, Jan Suetterlin, Ian Teasdale, Oliver Brueggemann, Jan-Patrick Bachmann, Christoph Ulbricht, Susanne Kimeswenger, Florian Hartmann
  • Publication number: 20230220147
    Abstract: The present invention relates to polyphosphazenes, polyurethanes based on these polyphosphazenes, methods for their manufacture and hydrogels based on the polyurethanes. The invention further relates to the use of the hydrogels in medical, veterinary and agricultural applications. The terminal ends of the polyphosphazenes bear NCO-reactive hydrogen atoms for reaction with polyisocyanates.
    Type: Application
    Filed: June 21, 2021
    Publication date: July 13, 2023
    Inventors: Jan Suetterlin, Heike Heckroth, Frank Richter, Ian Teasdale, Oliver Brueggemann, Oliver Plavcan
  • Patent number: 11530149
    Abstract: The present invention relates to an aqueous composition comprising cells of at least one strain of a halophilic microorganism, and alkali sulfate in a concentration of at least 30 g/l based on the total volume of the aqueous composition. The present invention further relates to a method for treating a waste water, comprising obtaining or providing a waste water, contacting said waste water with cells of at least one strain of a halophilic microorganism, and thereby generating an aqueous composition comprising alkali sulfate in a concentration of at least 30 g/l, and incubating said aqueous composition under conditions which allow for the treatment of the waste water.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: December 20, 2022
    Assignee: Covestro Intellectual Property GMBH & Co. KG
    Inventors: Heike Heckroth, Rainer Weber, Christoph Herwig, Nicole Mahler
  • Publication number: 20220298043
    Abstract: The present invention relates to a method for reducing the content of at least one pollutant selected from the group consisting of nitrobenzene, formate, phenol, 4,4?-Methylenedianilinc (MDA) and aniline of hypersaline wastewater, said method comprising the steps of (a) providing a composition A comprising hypersaline wastewater and said at least one pollutant, and (b) contacting composition A with Haloferax mediterranei cells, thereby generating a composition B comprising said composition A and cells of said at least one halophilic microbial strain. The present invention further concerns a method for the production of chlorine and sodium hydroxide. Further encompassed by the present invention is a composition comprising hypersaline wastewater, said at least one pollutant, and Haloferax mediterranei cells.
    Type: Application
    Filed: December 12, 2018
    Publication date: September 22, 2022
    Inventors: Heike HECKROTH, Christoph HERWIG, Donya KAMRAVAMANESH, Nicole MAHLER
  • Publication number: 20220135459
    Abstract: The present invention relates to a method for reducing the amount of organic compounds in wastewater, comprising providing a wastewater comprising NaCl in a concentration of at least 6% (w/v), contacting said hypersaline wastewater with a halophilic microorganism, and reducing the 5 amount of organic compounds by said halophilic microorganism in the presence of at least one substrate which has been added to the wastewater and which allows for the growth of said halophilic microorganism, wherein the reduction of the amount of organic components is carried out as a continuous process in bioreactor.
    Type: Application
    Filed: December 12, 2018
    Publication date: May 5, 2022
    Inventors: Heike HECKROTH, Rainer WEBER, Christoph HERWIG, Nicole MAHLER
  • Patent number: 11247925
    Abstract: The present invention relates to a method for reducing the aniline content of hypersaline wastewater, said method comprising the steps of (a) providing a composition A comprising hypersaline wastewater and aniline, and (b) contacting composition A with cells of at least one halophilic microbial strain, thereby generating a composition B comprising said composition A and cells of said at least one halophilic microbial strain. The present invention further concerns a method for the production of chlorine and sodium hydroxide. Further encompassed by the present invention is a composition comprising hypersaline wastewater, aniline, and cells of at least one halophilic microbial strain.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: February 15, 2022
    Assignee: COVESTRO DEUTSCHLAND AG
    Inventors: Heike Heckroth, Christoph Herwig, Donya Kamravamanesh
  • Publication number: 20210053855
    Abstract: The present invention relates to an aqueous composition comprising cells of at least one strain of a halophilic microorganism, and alkali sulfate in a concentration of at least 30 g/l based on the total volume of the aqueous composition. The present invention further relates to a method for treating a waste water, comprising obtaining or providing a waste water, contacting said waste water with cells of at least one strain of a halophilic microorganism, and thereby generating an aqueous composition comprising alkali sulfate in a concentration of at least 30 g/l, and incubating said aqueous composition under conditions which allow for the treatment of the waste water.
    Type: Application
    Filed: March 5, 2019
    Publication date: February 25, 2021
    Applicant: Covestro Intellectual Property GmbH & Co. KG
    Inventors: Heike HECKROTH, Rainer WEBER, Christoph HERWIG, Nicole MAHLER
  • Patent number: 10722609
    Abstract: The present invention relates to a method that includes providing a formulation having an isocyanate-functional prepolymer and a curing component comprising an amino-functional aspartic ester of the general formula (I) applying the formulation to a cell tissue; and curing the formulation such that the loss of blood (haemostatic) or tissue fluids is staunched or leaks in cell tissues are sealed.
    Type: Grant
    Filed: June 25, 2019
    Date of Patent: July 28, 2020
    Assignee: Adhesys Medical GmbH
    Inventors: Heike Heckroth, Burkhard Köhler, Sebastian Dörr
  • Publication number: 20200223973
    Abstract: Polyurea systems comprising: (a) an amino-functional aspartic ester of the general formula (I) wherein X represents an n-valent organic radical derived from a corresponding n-functional primary amine X(NH2)n, R1 and R2 each independently represent an organic radical having no Zerevitinov active hydrogens and n represents an integer of at least 2; and (b) an isocyanate functional prepolymer having a residual monomer content of less than 1% by weight, the prepolymer prepared by reacting: (b1) an aliphatic isocyante; and (b2) a polyol component having a number average molecular weight of ?400 g/mol and an average OH functionality of 2 to 6, wherein the polyol component comprises one or more constituents selected from the group consisting of polyester polyols, polyester-polyether polyols and mixtures thereof; processes for making the same; postoperative adhesions barriers prepared therewith and dispensing systems for such polyurea systems.
    Type: Application
    Filed: March 25, 2020
    Publication date: July 16, 2020
    Inventors: Heike HECKROTH, Hartmut NEFZGER, Christian WAMPRECHT
  • Patent number: 10633481
    Abstract: Polyurea systems comprising: (a) an amino-functional aspartic ester of the general formula (I) wherein X represents an n-valent organic radical derived from a corresponding n-functional primary amine X(NH2)n, R1 and R2 each independently represent an organic radical having no Zerevitinov active hydrogens and n represents an integer of at least 2; and (b) an isocyanate functional prepolymer having a residual monomer content of less than 1% by weight, the prepolymer prepared by reacting: (b1) an aliphatic isocyante; and (b2) a polyol component having a number average molecular weight of ?400 g/mol and an average OH functionality of 2 to 6, wherein the polyol component comprises one or more constituents selected from the group consisting of polyester polyols, polyester-polyether polyols and mixtures thereof; processes for making the same; postoperative adhesions barriers prepared therewith and dispensing systems for such polyurea systems.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: April 28, 2020
    Assignee: Adhesys Medical GmbH
    Inventors: Heike Heckroth, Hartmut Nefzger, Christian Wamprecht
  • Publication number: 20200046875
    Abstract: The present invention relates to a method that includes providing a formulation having an isocyanate-functional prepolymer and a curing component comprising an amino-functional aspartic ester of the general formula (I) applying the formulation to a cell tissue; and curing the formulation such that the loss of blood (haemostatic) or tissue fluids is staunched or leaks in cell tissues are sealed.
    Type: Application
    Filed: June 25, 2019
    Publication date: February 13, 2020
    Applicant: Adhesys Medical GmbH
    Inventors: Heike Heckroth, Burkhard KÖHLER, Sebastian DÖRR
  • Publication number: 20190352205
    Abstract: The present invention relates to a method for reducing the aniline content of hypersaline wastewater, said method comprising the steps of (a) providing a composition A comprising hypersaline wastewater and aniline, and (b) contacting composition A with cells of at least one halophilic microbial strain, thereby generating a composition B comprising said composition A and cells of said at least one halophilic microbial strain. The present invention further concerns a method for the production of chlorine and sodium hydroxide. Further encompassed by the present invention is a composition comprising hypersaline wastewater, aniline, and cells of at least one halophilic microbial strain.
    Type: Application
    Filed: January 9, 2018
    Publication date: November 21, 2019
    Inventors: Heike Heckroth, Christopher HERWIG, Donya KAMRAVAMANESH
  • Patent number: 10391198
    Abstract: The present invention relates to a method that includes providing a formulation having an isocyanate-functional prepolymer and a curing component comprising an amino-functional aspartic ester of the general formula (I) applying the formulation to a cell tissue; and curing the formulation such that the loss of blood (haemostatic) or tissue fluids is staunched or leaks in cell tissues are sealed.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: August 27, 2019
    Assignee: Adhesys Medical GmbH
    Inventors: Heike Heckroth, Burkhard Köhler, Sebastian Dörr
  • Publication number: 20190218126
    Abstract: The present invention relates to a method for reducing the formate content of hypersaline wastewater with cells of the Halomonas sp. strain MA-C. The present invention further concerns a method for the production of chlorine and/or sodium hydroxide. Further en-compassed by the present invention is a composition comprising hypersaline wastewater and cells of the Halomonas sp. strain MA-C.
    Type: Application
    Filed: August 24, 2017
    Publication date: July 18, 2019
    Applicant: Covestro Deutschland AG
    Inventors: Heike HECKROTH, Christoph HERWIG, Donya KAMRAVAMANESH, Paul RUSCHITZKA
  • Publication number: 20190030206
    Abstract: The present invention relates to a method that includes providing a formulation having an isocyanate-functional prepolymer and a curing component comprising an amino-functional aspartic ester of the general formula (I) applying the formulation to a cell tissue; and curing the formulation such that the loss of blood (haemostatic) or tissue fluids is staunched or leaks in cell tissues are sealed.
    Type: Application
    Filed: October 1, 2018
    Publication date: January 31, 2019
    Inventors: Heike HECKROTH, Burkhard KÖHLER, Sebastian DÖRR
  • Publication number: 20180347055
    Abstract: The invention relates to an electrochemical process for preparing bis-O-alkyl-carbamates from primary amines with CO2 as carbonyl source and at least one alkyl halide with at least three carbon atoms in the alkyl group as alkylating agent.
    Type: Application
    Filed: November 25, 2015
    Publication date: December 6, 2018
    Inventors: Frank Richter, Heike Heckroth, Vinh Trieu, Marta Feroci, Gianpiero Forte, Achille Inesi, Isabella Chiarotto
  • Patent number: 10117963
    Abstract: The present invention relates to a method that includes providing a formulation having an isocyanate-functional prepolymer and a curing component comprising an amino-functional aspartic ester of the general formula (I) applying the formulation to a cell tissue; and curing the formulation such that the loss of blood (haemostatic) or tissue fluids is staunched or leaks in cell tissues are sealed.
    Type: Grant
    Filed: August 3, 2017
    Date of Patent: November 6, 2018
    Assignee: Adhesys Medical GmbH
    Inventors: Heike Heckroth, Burkhard Köhler, Sebastian Dörr
  • Publication number: 20170326268
    Abstract: The present invention relates to a method that includes providing a formulation having an isocyanate-functional prepolymer and a curing component comprising an amino-functional aspartic ester of the general formula (I) applying the formulation to a cell tissue; and curing the formulation such that the loss of blood (haemostatic) or tissue fluids is staunched or leaks in cell tissues are sealed.
    Type: Application
    Filed: August 3, 2017
    Publication date: November 16, 2017
    Inventors: Heike Heckroth, Burkhard KOHLER, Sebastian DORR
  • Patent number: 9764058
    Abstract: The present invention relates to a method that includes providing a formulation having an isocyanate-functional prepolymer and a curing component comprising an amino-functional aspartic ester of the general formula (I) applying the formulation to a cell tissue; and curing the formulation such that the loss of blood (haemostatic) or tissue fluids is staunched or leaks in cell tissues are sealed.
    Type: Grant
    Filed: July 4, 2009
    Date of Patent: September 19, 2017
    Assignee: Adhesys Medical GmbH
    Inventors: Heike Heckroth, Burkhard Köhler, Sebastian Dörr
  • Patent number: 9757492
    Abstract: The present invention relates to a process for producing a hydroxy amino polymer comprising the steps: a) Reaction of an H functional starter compound bearing at least one Zerewitinoff active H atom with an unsaturated, cyclical carboxylic acid anhydride and at least one alkylene oxide compound for obtaining a prepolymer bearing hydroxyl groups, b) Addition of a primary amine and/or of ammonia to the double bond(s) of the prepolymer bearing hydroxyl groups obtained according to step a) for obtaining the hydroxy amino polymer, wherein the ratio of added amino groups to hydroxyl groups in a hydroxy amino polymer is at least 0.6. Furthermore, the invention relates to a hydroxy amino polymer, which can be achieved according to this process as well as a polyurea/polyurethane system, which contains such a hydroxy amino polymer.
    Type: Grant
    Filed: January 10, 2017
    Date of Patent: September 12, 2017
    Assignee: Adhesys Medical GmbH
    Inventors: Heike Heckroth, Christoph Eggert, Jörg Hofmann, Klaus Lorenz, Edward Browne, Hartmut Nefzger