Patents by Inventor Heike Heckroth

Heike Heckroth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8822479
    Abstract: The invention relates to 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolopyrimidines, process for their preparation, and their use for producing medicaments for improving learning and/or memory. The 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolopyrimidines are of the formula (I): with the variables as defined in the claims.
    Type: Grant
    Filed: November 19, 2010
    Date of Patent: September 2, 2014
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Martin Hendrix, Lars Bärfacker, Christina Erb, Frank-Thorsten Hafner, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • Patent number: 8809348
    Abstract: The invention relates to novel 6-arylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory.
    Type: Grant
    Filed: October 16, 2009
    Date of Patent: August 19, 2014
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Martin Hendrix, Lars Barfacker, Christine Erb, Frank-Thorsten Hafner, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • Publication number: 20140066981
    Abstract: The present invention relates to a polyurea system encompassing as component A) isocyanate-functional prepolymers obtainable by reaction of aliphatic isocyanates A1) with polyols A2), which can in particular have a number average molecular weight of ?400 g/mol and an average OH functionality of 2 to 6, as component B) amino-functional compounds of general formula (I) in which X is an organic residue comprising a tertiary amino function, having no Zerewitinoff active hydrogen, R1 is a CH2—COOR3 residue, in which R3 is an organic residue having no Zerewitinoff active hydrogen, a linear or branched C1 to C4 alkyl residue, a cyclopentyl or cyclohexyl residue or H, R2 is an organic residue having no Zerewitinoff active hydrogen, n is an integer ?2 or ?3, in particular for closing, binding, bonding or covering cell tissue, and to a metering system for the polyurea system according to the invention.
    Type: Application
    Filed: April 17, 2012
    Publication date: March 6, 2014
    Applicant: Bayer Intellectual Property GmbH
    Inventors: Heike Heckroth, Christoph Eggert
  • Publication number: 20140065091
    Abstract: The present invention relates to a polyurea system comprising as component A) isocyanate-functional prepolymers obtainable by reaction of aliphatic isocyanates A1) with polyols A2), which in particular can have a number-average molecular weight of ?400 g/mol and a mean OH functionality of from 2 to 6, as component B) an amino-functional compound of the general formula (I) in which X is an organic radical containing a secondary amino function, Y is an organic radical that contains a tertiary amino group and does not contain Zerewitinoff-active hydrogen, R1 is a CH2—COOR3 radical in which R3 is an organic radical that does not contain Zerewitinoff-active hydrogen, a linear or branched C1- to C4-alkyl radical, a cyclopentyl radical, a cyclohexyl radical or H, R2 is an organic radical that does not contain Zerewitinoff-active hydrogen, a is 1 or 2, b is 1 or 2, and a+b=2 or 3, for stemming the escape of blood, and to a metering system for the polyurea system according to the invention.
    Type: Application
    Filed: April 17, 2012
    Publication date: March 6, 2014
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Heike Heckroth, Christoph Eggert
  • Patent number: 8642605
    Abstract: The invention relates to novel 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory. The pyrazolopyrimidine compounds are within the formula (I) as described herein.
    Type: Grant
    Filed: September 15, 2011
    Date of Patent: February 4, 2014
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Martin Hendrix, Lars Bärfacker, Christina Erb, Frank-Thorsten Hafner, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • Publication number: 20130325062
    Abstract: The invention relates to a polyurea system comprising as component A) isocyanate-functional prepolymers which can be obtained by reacting aliphatic isocyanates A1) with polyols A2) that can have a number-average molecular weight of =400 g/mol and an average OH functionality of 2 to 6 in particular; and as component B) amino-functional aspartic acid esters of the general formula (I) in which X is an organic group containing a secondary amino function, R1, R2 are the same or different organic groups that do not have Zerewitinoff-active hydrogen, and n is a whole number of at least 2, in particular for sealing, bonding, gluing, or covering cell tissue. The invention also relates to a metering system for the polyurea system according to the invention.
    Type: Application
    Filed: February 6, 2012
    Publication date: December 5, 2013
    Applicant: Bayer Intellectual Property GmbH
    Inventors: Heike Heckroth, Christoph Eggert
  • Publication number: 20130317134
    Abstract: The present invention relates to a compound of formula (I) wherein R1, R2 each independently of the other are identical or different organic radicals which do not contain Zerewitinoff-active hydrogen, and R4, R5, R6 each independently of the others are saturated, linear or branched organic radicals which do not contain Zerewitinoff-active hydrogen and which are also optionally substituted in the chain by heteroatoms, for use in a polyurea system which is provided in particular for sealing, bonding, gluing or covering cell tissue. The invention further provides a polyurea system comprising the compound according to the invention, and a metering system for the polyurea system according to the invention.
    Type: Application
    Filed: February 6, 2012
    Publication date: November 28, 2013
    Applicant: Bayer Intellectual Property GmbH Creative Campus Monheim
    Inventors: Heike Heckroth, Christoph Eggert
  • Publication number: 20130136785
    Abstract: The invention relates to a wound dressing, comprising a liquid-absorbing substrate having active substance depots contained therein, wherein the active substance depots comprise particles of at least one active substance which are encapsulated in a silicone shell. The invention further relates to a wound dressing according to the invention for use as a means for treating wounds and to the use of a wound dressing according to the invention for producing a means for treating wounds.
    Type: Application
    Filed: February 8, 2011
    Publication date: May 30, 2013
    Applicant: Bayer Intellectual Property GmbH
    Inventors: Jan Schönberger, Michael Mager, Heike Heckroth, Doris Klee, Mona Wambach, Christoph Suschek
  • Patent number: 8431573
    Abstract: The invention relates to novel cyanopyrimidinones, process for their preparation, and the use thereof for producing medicaments for improving perception, concentration, learning and/or memory.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: April 30, 2013
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Martin Hendrix, Lars Bärfacker, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen
  • Publication number: 20130035235
    Abstract: The present invention relates to aqueous polyurethane dispersions for sealing teats of animal mammary glands.
    Type: Application
    Filed: December 6, 2010
    Publication date: February 7, 2013
    Applicant: Bayer Intellectual Property GmbH
    Inventors: Sebastian Dörr, Heike Heckroth, Jan Schönberger, Robrecht Froyman, Han-Robert Hehnen, Kristine Fraatz, Hans-Otto Werling
  • Publication number: 20120276382
    Abstract: The invention relates to an adhesive composite system comprising an adhesive layer of a tissue adhesive and a protective layer which is applied to the surface of the adhesive layer, said tissue adhesive being based on hydrophilic polyurethane polymers and the protective layer is water-proof. The invention also relates to a method for producing said adhesive composite system, to an adhesive composite system obtained according to said method, an adhesive composite system which can be used for covering, closing or gluing cellular tissue and to the use of the adhesive composite system for producing a product for covering, closing or gluing cellular tissue.
    Type: Application
    Filed: December 6, 2010
    Publication date: November 1, 2012
    Applicant: Bayer Intellectual Property GmbH
    Inventors: Sebastian Dörr, Heike Heckroth, Christoph Eggert
  • Publication number: 20120244107
    Abstract: The present invention relates to a hydrogel on the basis of polyurethane or polyurethane urea, said hydrogel comprising hydrolysable functional groups in the polymer chain, to a method for producing the hydrogel and to the use of the hydrogel as adhesion barriers.
    Type: Application
    Filed: October 7, 2010
    Publication date: September 27, 2012
    Applicant: Bayer MaterialScience AG
    Inventors: Heike Heckroth, Christoph Eggert, Hartmut Nefzger, Jörg Hofmann, Edward Browne, Klaus Lorenz
  • Publication number: 20120178847
    Abstract: The present invention relates to a polyurea system, the use of such a polyurea system for sealing, linking, gluing, or covering of cellular tissue, and a dosing system having two chambers for a polyurea system such as this. The polyurea system comprises as components: A) an isocyanate-functioning prepolymer, which can be derived by reacting aliphatic isocyanates with polyoles, and B) an amino-functioning ester of aspartic acid. According to the invention, water and/or tertiary amine is added to the system, in order to increase the reacting speed of the prepolymer with the amino-functioning ester of aspartic acid while decreasing the setting time at the same time.
    Type: Application
    Filed: July 6, 2010
    Publication date: July 12, 2012
    Applicant: Bayer MaterialScience AG
    Inventors: Heike Heckroth, Hartmut Nefzger, Christoph Eggert
  • Publication number: 20120010224
    Abstract: The invention relates to novel 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory.
    Type: Application
    Filed: September 15, 2011
    Publication date: January 12, 2012
    Inventors: Martin HENDRIX, Lars Bärfacker, Christina Erb, Frank-Thorsten Hafner, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • Patent number: 8088769
    Abstract: The invention relates to novel cyanopyrimidinones, process for their preparation, and the use thereof for producing medicaments for improving perception, concentration, learning and/or memory.
    Type: Grant
    Filed: December 31, 2004
    Date of Patent: January 3, 2012
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Martin Hendrix, Lars Bärfacker, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen
  • Publication number: 20110298335
    Abstract: The present invention relates to an electromechanical transducer, in particular an electromechanical sensor, actuator and/or generator, which exhibits a polymer element that is obtainable from a reaction mixture comprising a polyisocyanate or a polyisocyanate prepolymer or a mixture thereof and a compound with at least two isocyanate-reactive amino groups. Moreover, the present invention relates to a process for producing an electromechanical transducer of such a type and also to the use of a polymer element of such a type as an electromechanical element. Furthermore, the present invention relates to an electronic and/or electrical apparatus that includes an electromechanical transducer according to the invention, and also to the use of an electromechanical transducer according to the invention in an electronic and/or electrical apparatus.
    Type: Application
    Filed: July 17, 2009
    Publication date: December 8, 2011
    Applicant: BAYER MATERIALSCIENCE AG
    Inventors: Werner Jenninger, Sebastian Dörr, Joachim Wagner, Burkhard Köhler, Heike Heckroth, Mathias Matner
  • Patent number: 8058447
    Abstract: The present application relates to novel 4-chromenonyl-1,4-dihydropyridinecarbonitriles, processes for their preparation, pharmaceutical compositions containing them, and their use for the treatment and/or prophylaxis of diseases, especially cardiovascular disorders.
    Type: Grant
    Filed: July 14, 2006
    Date of Patent: November 15, 2011
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Alexander Kuhl, Peter Kolkhof, Heike Heckroth, Karl-Heinz Schlemmer, Ingo Flamme, Santiago Figueroa Perez, Heike Gielen-Haertwig, Rolf Grosser, Jens-Kerim Ergüden, Dieter Lang
  • Patent number: 8044060
    Abstract: Described are 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolo[3,4-d]pyrimidines of the formula (I): as defined herein, processes for their preparation and their use for producing medicaments for treating impairment of perception, concentration, learning and/or memory.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: October 25, 2011
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Martin Hendrix, Lars Bärfacker, Christina Erb, Frank-Thorsten Hafner, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • Publication number: 20110245351
    Abstract: The invention relates to novel rapidly-curing adhesives made from hydrophilic polyisocyanate prepolymers for application in surgery.
    Type: Application
    Filed: November 28, 2009
    Publication date: October 6, 2011
    Applicant: BAYER MATERIALSCIENCE AG
    Inventors: Heike Heckroth, Burkhard Köhler
  • Publication number: 20110207735
    Abstract: The invention relates to novel cyanopyrimidinones, process for their preparation, and the use thereof for producing medicaments for improving perception, concentration, learning and/or memory.
    Type: Application
    Filed: May 2, 2011
    Publication date: August 25, 2011
    Inventors: Martin HENDRIX, Lars BÄRFACKER, Heike Heckroth, Dagmar KARTHAUS, Adrian TERSTEEGEN