Patents by Inventor Heinrich Kladders

Heinrich Kladders has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200215275
    Abstract: A nebulizer for nebulizing a liquid from a container includes a fluid pump for withdrawing the liquid in doses from the container and pressurizing the respective doses for nebulization. The nebulizer includes in addition an air pump with a piston/cylinder arrangement for pumping air into the container to pressurize the liquid in the container to help withdrawing the liquid from the container.
    Type: Application
    Filed: July 23, 2018
    Publication date: July 9, 2020
    Applicant: Boehringer lngelheim International GmbH
    Inventors: Heinrich KLADDERS, Thomas WABNITZ, Herbert GRAESSL, Andree JUNG, Gilbert WUTTKE
  • Publication number: 20200179620
    Abstract: A nebulizer for nebulizing a liquid from a container, where the nebulizer includes a fluid pump for withdrawing the liquid in doses from the container and pressurizing the respective doses for nebulization. The container includes an air pump with a piston/cylinder arrangement to pressurizing the liquid in the container to help withdrawing the liquid from the container. A control valve limits the air pressure acting on the liquid.
    Type: Application
    Filed: July 23, 2018
    Publication date: June 11, 2020
    Applicant: Boehringer lngelheim International GmbH
    Inventors: Gilbert WUTTKE, Herbert GRAESSL, Heinrich KLADDERS
  • Patent number: 10220165
    Abstract: The invention relates to a capsule for receiving a preferably powdered pharmaceutical preparation and an inhaler in which, for inhalation, the preparation is expelled from the capsule through at least one hole. A capsule according to the invention comprises as capsule elements a capsule cap and a capsule body, at least one of which comprises at least one prefabricated hole. Systems according to the invention comprising inhalers and capsules are described, in which the prefabricated hole in the capsule is sealed off in the transporting state of the system and is open in the usage state. The hole is exposed by actuation of a pushing or pulling mechanism. Prior to this the hole is closed off by part of the capsule itself or by a capsule receptacle belonging to the inhaler. In one embodiment the capsule may be present in two different states, for example in different insertion positions of the capsule elements. In the first state the prefabricated hole is closed off and in the second it is exposed.
    Type: Grant
    Filed: May 21, 2012
    Date of Patent: March 5, 2019
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Stephen Terence Dunne, Jens Besseler, Jessica Frentzel-Beyme, Holger Holakovsky, Heinrich Kladders, Claudius Weiler, Ole Zumblick
  • Publication number: 20170209892
    Abstract: A nebulizer for nebulizing a liquid from a container is proposed. The nebulizer comprises a liquid pump for withdrawing the liquid in doses from the container and pressurizing the respective doses for nebulization. The nebulizer comprises in addition an air pump for temporarily pressurizing the liquid in the container to help withdrawing the liquid from a collapsible bag in the container.
    Type: Application
    Filed: January 20, 2017
    Publication date: July 27, 2017
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Heinrich KLADDERS, Matthias HAUSMANN
  • Patent number: 9364841
    Abstract: An inhaler including a pre-inserted cartridge (100) is proposed. The cartridge contains liquid (103) which is preferably pressurized to a low pressure. The cartridge is connected via an aerosol valve (106) with the inhaler. The liquid is further pressurized by a pump (117) of the inhaler to a high pressure and atomized.
    Type: Grant
    Filed: February 18, 2009
    Date of Patent: June 14, 2016
    Assignee: BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG
    Inventors: Stephen T. Dunne, Heinrich Kladders
  • Patent number: 8905017
    Abstract: A reservoir and a nebulizer having such a reservoir are proposed. The reservoir comprises a closure for a fluid chamber with a medicament formulation that is formed by two closure members welded together. The closure comprises a particle barrier for preventing the ingress into the fluid chamber of any weld particles that may potentially be formed during the welding of the two closure members. The fluid chamber is preferably broadened in the shape of a beaver tail and is sealed lengthways with an additional strip of material.
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: December 9, 2014
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Matthias Hausmann, Carsten Henning, Heinrich Kladders
  • Publication number: 20140182587
    Abstract: The invention relates to a capsule for receiving a preferably powdered pharmaceutical preparation and an inhaler in which, for inhalation, the preparation is expelled from the capsule through at least one hole. A capsule according to the invention comprises as capsule elements a capsule cap and a capsule body, at least one of which comprises at least one prefabricated hole. Systems according to the invention comprising inhalers and capsules are described, in which the prefabricated hole in the capsule is sealed off in the transporting state of the system and is open in the usage state. The hole is exposed by actuation of a pushing or pulling mechanism. Prior to this the hole is closed off by part of the capsule itself or by a capsule receptacle belonging to the inhaler. In one embodiment the capsule may be present in two different states, for example in different insertion positions of the capsule elements. In the first state the prefabricated hole is closed off and in the second it is exposed.
    Type: Application
    Filed: May 21, 2012
    Publication date: July 3, 2014
    Applicant: Boehringer Ingelheim international GmbH
    Inventors: Stephen Terence Dunne, Jens Besseler, Jessica Frentzel-Beyme, Holger Holakovsky, Heinrich Kladders, Claudius Weiler, Ole Zumblick
  • Patent number: 8584669
    Abstract: An inhaler (1) is proposed (see FIG. 1), for the inhalation of a formulation (2) from capsules (3) that each contain one dose of the formulation. The capsules are preferably each emptied in a capsule chamber (4) by being set in motion by a stream of air flowing through the capsule chamber. The stream of air can be generated by the inhalation of a user or patient and/or can be generated actively generated by the inhaler. For simple handling, the inhaler has a means for, in particular, automatic filling, emptying and/or cleaning of the capsule chamber, if the latter is used more than once. Alternatively, the inhaler has a large number of capsule chambers that each preferably already contain a capsule and re preferably used just once.
    Type: Grant
    Filed: April 11, 2007
    Date of Patent: November 19, 2013
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Jens Besseler, Hubert Kunze, Achim Moser, Ralf Thoemmes, Gilbert Wuttke, Dieter Hochrainer, Heinrich Kladders, Christoph Dworzak, Josef Eckert, Antonio Lanci, Markus Mast, Elmar Mock, Andre Klopfenstein
  • Patent number: 8539947
    Abstract: An inhaler for inhaling powdered medicaments from capsules, having: a lower part which is cup-shaped, a plate latched to the lower part to close off the lower part, a capsule holder arranged on the underside of the plate, a mouthpiece that can be latched to the top of plate, and an actuating member for interacting with at least one pin for piercing a capsule in the capsule holder, where the actuating member includes a larger outer actuating member and a smaller inner actuating member, the outer actuating member forms a user-operated push-button, the inner actuating member contacts and holds the pin below a suspension element of the outer actuating member from the plate, and the point of application of force by the user onto push-button is lower than the inner actuating member.
    Type: Grant
    Filed: July 17, 2008
    Date of Patent: September 24, 2013
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Rolf Kuhn, Burkhard Peter Metzger, Torsten Kuehn, Heinrich Kladders, Joern-Eric Schulz
  • Patent number: 8528548
    Abstract: An inhaler (1) is proposed for inhaling a preparation (2) from a carrier (3) and/or through a delivery channel (16) as depicted in exemplary FIG. 1. The carrier or delivery channel is preferably flexible, flat, band-shaped, strip-shaped, thread-like, blister-like and/or film-like and can be set in vibration by a stream of air (5). The carrier or delivery channel is preferably set in vibration by a separate element (6), which for its part is set in motion or vibration by the stream of air. Alternatively, or in addition, the inhaler has a pump (10) with a telescopic pump chamber (20) for generating a stream of air for expelling and/or dispersing a preparation.
    Type: Grant
    Filed: August 17, 2007
    Date of Patent: September 10, 2013
    Assignee: Boehringer Ingelheim International GmbH
    Inventor: Heinrich Kladders
  • Patent number: 8205613
    Abstract: A preferably pulverulent formulation to be dosed is received in a dosing chamber having a partly gas-permeable wall. The introduction and discharge of the formulation is achieved by means of a pumping device that alternately generates a negative pressure and an excess pressure in the dosing chamber. The dosing chamber can also be displaced between a receiving position and a discharge position by means of a piston, the piston controlling the negative and excess pressure in the dosing chamber. Furthermore, the size of the dosing chamber is adjustable.
    Type: Grant
    Filed: August 17, 2007
    Date of Patent: June 26, 2012
    Assignee: Boehringer Ingelheim International GmbH
    Inventor: Heinrich Kladders
  • Publication number: 20120132198
    Abstract: A reservoir and a nebuliser having such a reservoir are proposed. The reservoir comprises a closure for a fluid chamber with a medicament formulation that is formed by two closure members welded together. The closure comprises a particle barrier for preventing the ingress into the fluid chamber of any weld particles that may potentially be formed during the welding of the two closure members. The fluid chamber is preferably broadened in the shape of a beaver tail and is sealed lengthways with an additional strip of material.
    Type: Application
    Filed: March 12, 2010
    Publication date: May 31, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Matthias Hausmann, Carsten Henning, Heinrich Kladders
  • Patent number: 8001965
    Abstract: The invention relates to a novel capsule for receiving an active substance to be administered by inhalation, which is preferably intended for use in a powder inhaler operating on the Bernoulli principle.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: August 23, 2011
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Heinrich Kladders, Burkhard Metzger, Dieter Hochrainer
  • Publication number: 20110168175
    Abstract: An inhaler including a pre-inserted cartridge (100) is proposed. The cartridge contains liquid (103) which is preferably pressurized to a low pressure. The cartridge is connected via an aerosol valve (106) with the inhaler. The liquid is further pressurized by a pump (117) of the inhaler to a high pressure and atomized.
    Type: Application
    Filed: February 18, 2009
    Publication date: July 14, 2011
    Applicant: BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG
    Inventors: Stephen T. Dunne, Heinrich Kladders
  • Patent number: 7963955
    Abstract: Foil bags are used as a primary packaging for liquids, the bags permitting the liquid to be taken therefrom without the application of a considerable amount of force. A container is provided for a medicinal liquid, the container being gas-tight and liquid-tight so that it is storable over many months. The container includes a collapsible foil bag on which a flange, which is stable in respect of shape, is disposed. The flange is designed for fitting onto a discharge connection member. The container can be disposed in a casing which is stable in respect of shape. The medicinal liquid does not come into contact with air and is protected from the effect of light. The medicinal liquid may be dispensed from the foil bag in many partial quantities over a prolonged period of time, with a respective partial amount thereof being converted into an aerosol by means of an atomizer.
    Type: Grant
    Filed: January 12, 2004
    Date of Patent: June 21, 2011
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Bernhard Freund, Dieter Hochrainer, Heinrich Kladders, Bernd Zierenberg, Joachim Eicher, Johannes Geser, Martin Essing, Holger Reinecke
  • Patent number: 7950388
    Abstract: A nebuliser and a container in each case with an aeration device are proposed, the aeration device being designed for the direct aeration of a liquid space in the container. The container comprises a rigid, gas-tight outer case and a closure, which is opened by connecting or inserting a delivery element. A long storage life and long service life with low loss of fluid or solvent are thereby provided in the form of a simple and inexpensive construction.
    Type: Grant
    Filed: June 26, 2006
    Date of Patent: May 31, 2011
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Hubert Kunze, Matthias Hausmann, Jens Besseler, Carsten Henning, Heinrich Kladders, Florian Witte, Johannes Geser, Markus Mast, Antonino Lanci, Christoph Dworzak, Elmar Mock
  • Patent number: 7878193
    Abstract: The invention relates to a novel capsule for receiving an active substance to be administered by inhalation, which is preferably intended for use in a powder inhaler operating on the Bernoulli principle.
    Type: Grant
    Filed: January 14, 2004
    Date of Patent: February 1, 2011
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Heinrich Kladders, Burkhard Metzger, Dieter Hochrainer
  • Publication number: 20100275917
    Abstract: The present invention relates to a method, a device, and a control program for the fluid-tight sealing of capsules containing medicaments, wherein the capsules consist of at least one capsule body and a capsule cap which are set one into the other telescopically and provided with a tight band in the abutment region on the exterior side of the capsule, wherein the capsule components are filled with gas which has a changed temperature and/or a changed pressure in relation to the environment, and wherein a reduction of the difference in pressure in the capsule occurs via gaps between capsule body and capsule cap after the capsule components have been placed one inside the other. The capsules produced via the method according to the invention are disposable capsules and preferably contain a single dose of an orally administered pharmaceutical formulation in the form of a powder or a liquid.
    Type: Application
    Filed: July 17, 2008
    Publication date: November 4, 2010
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Rolf Kuhn, Burkhard Peter Metzger, Torsten Kuehn, Heinrich Kladders, Joern-Eric Schulz
  • Patent number: 7802568
    Abstract: For meteredly dispensing a liquid over a period of several months from a container which can be stored over a long period of time, the need is for a container which is practically diffusion-tight and in which the liquid does not come into contact with the ambient atmosphere. The cartridge according to the invention is a three-shell container comprising a collapsible bag which contains the liquid, a container which is stable in respect of shape and a stiff metal casing. The cartridge can be releasably connected to a dispensing device. The cartridge can be provided with a micro-opening with which the time for pressure equalisation between the cartridge and the ambient atmosphere can be adjusted. The cartridge is suitable for aqueous and for alcoholic liquids which contain a pharmaceutically active substance. The liquid in the cartridge is protected from external influences. The cartridge can be used in an atomiser for producing an inhalable aerosol for the treatment of illnesses.
    Type: Grant
    Filed: September 23, 2005
    Date of Patent: September 28, 2010
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Joachim Eicher, Johannes Geser, Matthias Hausmann, Michael Schyra, Gilbert Wuttke, Andreas Fiol, Heinrich Kladders, Dieter Hochrainer, Bernd Zierenberg
  • Publication number: 20100059051
    Abstract: The invention relates to an inhaler (1) for inhaling a formulation (2), said inhaler comprising a filiform support (4) for metering and/or conveying the formulation.
    Type: Application
    Filed: August 17, 2007
    Publication date: March 11, 2010
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventor: Heinrich Kladders