Patents by Inventor Heinz Kohler

Heinz Kohler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6406360
    Abstract: A device for cleaning the inner walls of vulcanizing molds that are divided into upper and lower partial molds by means of a blasting device/nozzle and a manipulating device, with the blasting device and the manipulating device being accommodated and encapsulated in an isolation hood that is provided with an adapter ring, and with the isolation hood being suspended on a movable boom and connectable to the outer circumference of a partial mold by means of the adapter ring.
    Type: Grant
    Filed: August 2, 2000
    Date of Patent: June 18, 2002
    Assignee: Continental Aktiengesellschaft
    Inventors: Nhu Vinh Nguyen, Martin Gonschior, Robert Pohlmann, Heinz Köhler, Marc Rapin, Karsten Wenzel, Leo Pontzen, Heinrich Schnell, Holger Brandt, Wolfgang Kuhr
  • Publication number: 20010047083
    Abstract: The present invention provides a monoclonal anti-idiotype antibody 3H1 that escapes immune tolerance and elicits a specific immune response to CEA in mice, rabbits, monkeys, and patients with advanced CEA-associated disease. This invention also provides compositions which can be used in the detection or treatment of CEA-associated tumors mimics a specific epitope on carcinoembryonic antigen and a hybridoma that produces 3H1.
    Type: Application
    Filed: February 28, 2001
    Publication date: November 29, 2001
    Inventors: Malaya Chatterjee, Heinz Kohler, Sunil K. Chatterjee, Kenneth A. Foon
  • Patent number: 6238667
    Abstract: A method of affinity cross-linking a peptide to an antibody by photo-chemically activating an azido compound in a peptide including said azido compound; adding an antibody to the photochemically activated peptide; and allowing the photochemically activated peptide and the antibody to react. The azido compound has an affinity for a hydrophobic structure in the variable domain of the antibody which binds to nucleotides or nucleosides, binding the peptide into a native binding pocket of the immunoglobulin (Ig) structure of an antibody. The site of cross-linking is located away from the antigen binding site in the Fv domain avoiding the compromise of antigen recognition. A composition of a peptide cross-linked to an antibody is also disclosed.
    Type: Grant
    Filed: May 4, 1998
    Date of Patent: May 29, 2001
    Inventor: Heinz Kohler
  • Patent number: 6057421
    Abstract: The amino acid sequences of variable heavy and variable light domains of murine monoclonal antibody 1F7 are reported. Methods of use for products containing these sequences in the diagnosis and the treatment of HIV infection and AIDS are also described.
    Type: Grant
    Filed: December 3, 1997
    Date of Patent: May 2, 2000
    Assignee: Immpheron, Inc.
    Inventors: Sybille Muller, Heinz Kohler
  • Patent number: 5977315
    Abstract: The present invention provides a monoclonal anti-idiotype antibody 3H1 that escapes immune tolerance and elicits a specific immune response to CEA in mice, rabbits, monkeys, and patients with advanced CEA-associated disease. This invention also provides compositions which can be used in the detection or treatment of CEA-associated tumors mimics a specific epitope on carcinoembryonic antigen and a hybridoma that produces 3H1.
    Type: Grant
    Filed: December 28, 1995
    Date of Patent: November 2, 1999
    Assignee: The Board of Trustees of the University of Kentucky
    Inventors: Malaya Chatterjee, Heinz Kohler, Sunil K. Chatterjee, Kenneth A. Foon
  • Patent number: 5800991
    Abstract: Sites on antibodies having affinity for photoaffinity compounds, in particular purine or azidopurine containing compounds are taught. Such photoaffinity sites are contained on a conserved region of different antibody molecules. These sites provide for the site-specific attachment of nucleotide photoaffinity compounds to antibodies, e.g., ATP- or GTP-analog photoaffinity compounds by photochemical means. These nucleotide photoaffinity compounds may additionally be attached to molecules having a desired therapeutic or diagnostic activity, and the resultant conjugates used as diagnostics or therapeutics.
    Type: Grant
    Filed: July 23, 1996
    Date of Patent: September 1, 1998
    Assignee: University of Kentucky Research Foundation
    Inventors: Boyd E. Haley, Heinz Kohler, Krishnan Rajagopalan, Gabriela Pavlinkova
  • Patent number: 5693764
    Abstract: Sites on antibodies having affinity for photoaffinity compounds, in particular purine or azidopurine containing compounds are taught. These sites provide for the site-specific attachment of nucleotide photoaffinity compounds to antibodies, e.g., ATP- or GTP-analog photoaffinity compounds by photochemical means. These nucleotide photoaffinity compounds may additionally be attached to molecules having a desired therapeutic or diagnostic activity, and the resultant conjugates used as diagnostics or therapeutics.
    Type: Grant
    Filed: April 18, 1996
    Date of Patent: December 2, 1997
    Assignee: The University of Kentucky Research Foundation
    Inventors: Boyd E. Haley, Heinz Kohler, Krishnan Rajagopalan, Gabriela Pavlinkova
  • Patent number: 5632953
    Abstract: A coke-fired cupola, including: a furnace shaft having a well at one end, a charging device connected to the shaft, a lower-mouth exhaust connected to the shaft below the charging device, and a furnace gas exhaust ring arranged at the shaft below the charging device and the lower-mouth exhaust. Additionally, at least one nozzle is connected to the shaft above the well. The at least one nozzle has a centrally run oxygen lance. A gas recirculating circuit is provided for connecting the furnace gas exhaust ring to the at least one nozzle. The gas recirculating circuit includes an exhaust device connected to the furnace gas exhaust ring, a recirculating gas ring connected to the at least one nozzle and a recirculating gas duct connected between the exhaust device and the recirculating gas ring.
    Type: Grant
    Filed: September 11, 1995
    Date of Patent: May 27, 1997
    Assignees: Hans U. Feustel, Joachim Mallon, Michael Schaaf
    Inventors: Hans U. Feustel, Joachim Mallon, Michael Schaaf, Edmund Wilms, Gerhard Neumann, Karl-Heinz Kohler, Ludwig Ruschitzka
  • Patent number: 5596081
    Abstract: Sites on antibodies having affinity for photoaffinity compounds, in particular purine or azidopurine containing compounds are taught. These sites provide for the site-specific attachment of nucleotide photoaffinity compounds to antibodies, e.g., ATP- or GTP-analog photoaffinity compounds by photochemical reaction. These nucleotide photoaffinity compounds may additionally be attached to molecules having a desired therapeutic or diagnostic activity, and the resultant conjugates used as diagnostics or therapeutics.
    Type: Grant
    Filed: March 11, 1994
    Date of Patent: January 21, 1997
    Assignee: University of Kentucky Research Foundation
    Inventors: Boyd E. Haley, Heinz Kohler, Krishnan Rajagopalan, Gabriela Pavlinkova
  • Patent number: 5556818
    Abstract: A substituted barium-neodymium-titanium-perovskite which has a defect structure and which has the following general composition:[A'.sub.al.sup.ml+ A".sub.a2.sup.n2+ . . . A.sup.n '.sub.an.sup.n.spsp.n.sup.+ .box-solid..sub.an+1 ] [B'.sub.b1.sup.m1+ B".sub.b2.sup.m2 + . . . B.sup.m '.sub.bm.sup.m.spsp.n.sup.+] O.sub.3,wherein the cations A'.sub.a1.sup.n1+ A".sub.a2.sup.n2+ . . . A.sup.n '.sub.an.sup.n.spsp.n.sup.+ at least comprise Ba.sup.2+, Nd.sup.3+ and, optionally, one or more cations of the group consisting of Cs.sup.1+, Rb.sup.1+, Tl.sup.1+, K.sup.1+, Pb.sup.2+, Ag.sup.1+, Sr.sup.2+, Na.sup.1+, Bi.sup.3+, La.sup.3+, Ca.sup.2+, Ce.sup.3+, Cd.sup.2+, Pr.sup.3+, Sm.sup.3+, Eu.sup.3+, Gd.sup.3+, Th.sup.4+, Tb.sup.3+, Mn.sup.2+, Li.sup.1+, Dy.sup.3+, U.sup.4+, Y.sup.3+, Fe.sup.2+, Ho.sup.3+, Ce.sup.4+, Co.sup.2+, Zn.sup.2+, Er.sup.3+, Tm.sup.3+, Yb.sup.3+, and/or Lu.sup.3+, and the cations B'.sub.b1.sup.m1+ B".sub.b2.sup.m2+ . . . B.sup.m '.sub.bm.sup.m.spsp.n.sup.+ at least comprise titanium Ti.sup.
    Type: Grant
    Filed: September 30, 1994
    Date of Patent: September 17, 1996
    Assignee: U.S. Philips Corporation
    Inventors: Heinz Kohler, Dieter Mateika, Sietse Oostra
  • Patent number: 5523208
    Abstract: A method for scanning nucleotide or DNA sequence data banks to identify genetic regions or genes coding for biologically interacting proteins.
    Type: Grant
    Filed: November 30, 1994
    Date of Patent: June 4, 1996
    Assignee: The Board of Trustees of The University of Kentucky
    Inventors: Heinz Kohler, J. Edwin Blalock
  • Patent number: 5234984
    Abstract: This invention relates to crystalline, thermoplastic moulding compounds of polyphenylene sulphide (PPS) and aliphatically saturated carboxylic acid esters. The moulding compounds have increased tracking resistance.
    Type: Grant
    Filed: July 23, 1990
    Date of Patent: August 10, 1993
    Assignee: Bayer Aktiengesellschaft
    Inventors: Karl-Heinz Kohler, Wolfgang Wehnert, Klaus Kraft, Erhard Tresper
  • Patent number: 5108823
    Abstract: Circuit boards having excellent electrical and mechanical properties are obtained when special mixtures of polyarylene sulfides and polycarbonates, polyaryl ethers, polyamides, polyesters or rubber elastomers are used as base plates for the wet-chemical deposition of the circuits and the boards are treated with an oxidizing agent before activation.
    Type: Grant
    Filed: January 2, 1990
    Date of Patent: April 28, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: Kirkor Sirinyan, Karl-Heinz Kohler, Klaus Reinking, Wolfgang Russeler, Wolfgang Wehnert
  • Patent number: 5093468
    Abstract: The invention relates to high molecular weight, substantially linear copolyarylene sulfides predominantly containing biphenylene sulfide units, which are produced by reaction of aromatic halogen compounds and halobiphenylenes with sulfur donors in dipolar aprotic solvents, and to their use for moldings, films and fibers exposed to high temperatures and--preferably in reinforced form--as injection molding compounds.
    Type: Grant
    Filed: September 4, 1990
    Date of Patent: March 3, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventor: Karl-Heinz Kohler
  • Patent number: 5064895
    Abstract: The invention relates to molding compounds of polyarylene sulfides (PAS), preferably polyphenylene sulfides (PPS), which have a low ion content and delayed crystallization and to their use as an encapsulating compound for active and passive electronic components.
    Type: Grant
    Filed: August 7, 1989
    Date of Patent: November 12, 1991
    Assignee: Bayer Aktiengesellschaft
    Inventors: Karl-Heinz Kohler, Klaus Reinking, Klaus Kraft
  • Patent number: 5032674
    Abstract: The invention relates to molding compounds of polyarylene sulfides (PAS), preferably polyphenylene sulfides (PPS), which have a low ion content and delayed crystallization and to their use as an encapsulating compound for active and passive electronic components.
    Type: Grant
    Filed: December 4, 1990
    Date of Patent: July 16, 1991
    Assignee: Bayer Aktiengesellschaft
    Inventors: Karl-Heinz Kohler, Klaus Reinking, Klaus Kraft
  • Patent number: 5001220
    Abstract: This invention relates to new high molecular weight, optionally branched co-polyarylene sulphides prepared by the reaction of halogenated aromatic compounds and dihalogenated phenyl-pyrazole-3-ones in a polar solvent with the addition of 0.2 to 100 mol %, based on the dihalogenated aromatic compound, of an amino acid to the reaction mixture, and to the use of these copolyarylene sulphides as embedding compounds for electronic parts.
    Type: Grant
    Filed: March 3, 1989
    Date of Patent: March 19, 1991
    Assignee: Bayer AG
    Inventors: Karl-Heinz Kohler, Klaus Reinking
  • Patent number: 4749755
    Abstract: Polyalkylene terephthalates which contain small quantities of aliphatic polycarbonate show improved fracture behavior, without a significant adverse effect on the strength and the flowability in the melt. Moreover, the compositions show improved behavior in hot-air ageing.
    Type: Grant
    Filed: May 30, 1986
    Date of Patent: June 7, 1988
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans-Josef Buysch, Norbert Schon, Wolfgang Richter, Rudolf Binsack, Karl-Heinz Kohler, Dieter Rempel
  • Patent number: 4686262
    Abstract: Block copolyesters based on polyalkylene terephthalates which contain polydiene blocks show an extremely low deformation even when they are processed into thin articles. They still have a crystallinity which is decreased by less than the ratio corresponding to the polydiene portion.
    Type: Grant
    Filed: December 14, 1981
    Date of Patent: August 11, 1987
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rudolf Binsack, Karl-Heinz Kohler, Ulrich Grigo, Leo Morbitzer, Ludwig Bottenbruch, Walter Heitz
  • Patent number: D472954
    Type: Grant
    Filed: January 17, 2002
    Date of Patent: April 8, 2003
    Assignee: ubd Urban Design Berlin GmbH
    Inventor: Karl-Heinz Köhler