Patents by Inventor Helen Francis-Lang

Helen Francis-Lang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pfks as modifiers of the igfr pathway and methods of use
    Publication number: 20090142272
    Abstract: Human PFK genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of PFK are provided.
    Type: Application
    Filed: June 20, 2005
    Publication date: June 4, 2009
    Applicant: Exelixis, Inc.
    Inventors: Lori S. Friedman, Helen Francis-Lang, Annette L. Parks, Kenneth James Shaw, Lynn Margaret Bjerke, Timothy S. Heuer
  • MAP3Ks as modifiers of the p53 pathway and methods of use
    Publication number: 20090068186
    Abstract: Human MAP3K genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of MAP3K are provided.
    Type: Application
    Filed: April 18, 2007
    Publication date: March 12, 2009
    Applicant: Exelixis Inc.
    Inventors: Lori Friedman, Gregory D. Plowman, Marcia Belvin, Helen Francis-Lang, Danxi Li, Roel P. Funke
  • GALNTS AS MODIFIERS OF THE IGFR PATHWAY AND METHODS OF USE
    Publication number: 20090028844
    Abstract: Human MIGFR genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of MIGFR are provided.
    Type: Application
    Filed: June 20, 2005
    Publication date: January 29, 2009
    Applicant: EXELIXIS, INC.
    Inventors: Lori S. Friedman, Helen Francis-Lang, Annette L. Parks, Kenneth James Shaw, Timothy S. Heuer, Lynn Margaret Bjerke
  • P4HAS AS MODIFIERS OF THE IGFR PATHWAY AND METHODS OF USE
    Publication number: 20090025096
    Abstract: Human P4HA genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of P4HA are provided.
    Type: Application
    Filed: June 20, 2005
    Publication date: January 22, 2009
    Applicant: EXELIXIS, INC.
    Inventors: Lori S. Friedman, Helen Francis-Lang, Annette L. Parks, Kenneth James Shaw, Timothy S. Heuer, Lynn Margaret Bjerke
  • PDES AS MODIFIERS OF THE IGFR PATHWAYS AND METHODS OF USE
    Publication number: 20090013416
    Abstract: Human PDE genes are identified as modulators of the IGFR pathway and thus are therapeutic targets for disorders associated with defective IGFR function Methods for identifying modulators of IGFR comprising screening for agents that modulate the activity of PDE are provided
    Type: Application
    Filed: March 10, 2005
    Publication date: January 8, 2009
    Applicant: EXELIXIS, INC.
    Inventors: Lori Friedman, Helen Francis-Lang, Annette L. Parks, Kenneth James Shaw, Lynn Margaret Bjerke, Timothy S. Heuer
  • Plks as Modifiers of the Beta Catenin Pathway and Methods of Use
    Publication number: 20080274122
    Abstract: Human PLK genes are identified as modulators of the beta catenin pathway, and thus are therapeutic targets for disorders associated with defective beta catenin function. Methods for identifying modulators of beta catenin, comprising screening for agents that modulate the activity of PLK are provided.
    Type: Application
    Filed: November 23, 2004
    Publication date: November 6, 2008
    Applicant: EXELIXIS, INC.
    Inventors: Helen Francis-Lang, Christopher G. Winter, Richard Benn Abegania Ventura, Lynn Margaret Bjerke, Timothy S. Heuer
  • MARKs as Modifiers of the p53 Pathway and Methods of Use
    Publication number: 20080166709
    Abstract: Human MARK genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of MARK are provided.
    Type: Application
    Filed: January 28, 2007
    Publication date: July 10, 2008
    Applicant: EXELIXIS, INC.
    Inventors: Lori Friedman, Gregory D. Plowman, Marcia Belvin, Helen Francis-Lang, Danxi Li, Roel P. Funke, Mario N. Lioubin
  • SCDs As Modifiers of the p53 Pathway and Methods of Use
    Publication number: 20080102070
    Abstract: Human SCD genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of SCD are provided.
    Type: Application
    Filed: September 10, 2007
    Publication date: May 1, 2008
    Applicant: EXELIXIS, INC.
    Inventors: Marcia Belvin, Helen Francis-Lang, Lori Friedman, Gregory Plowman, Timothy Heuer
  • Sulfs as Modifiers of the Beta-Catenin Pathway and Methods of Use
    Publication number: 20080050313
    Abstract: Human SULF genes are identified as modulators of the beta catenin pathway, and thus are therapeutic targets for disorders associated with defective beta catenin function. Methods for identifying modulators of beta catenin, comprising screening for agents that modulate the activity of SULF are provided.
    Type: Application
    Filed: August 12, 2004
    Publication date: February 28, 2008
    Applicant: Exelixis, Inc.
    Inventors: Helen Francis-Lang, Christopher G. Winter, Richard Benn Abegania Ventura, HaiGuang Zhang, Timothy S. Heuer
  • Itpks as Modifiers of the Igfr Pathway and Methods of Use
    Publication number: 20070292349
    Abstract: Human MIGFR genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of MIGFR are provided.
    Type: Application
    Filed: January 27, 2005
    Publication date: December 20, 2007
    Applicant: Exelixis, Inc.
    Inventors: Lori Friedman, Helen Francis-Lang, Annette Parks, Kenneth Shaw, Lynn Bjerke, Timothy Heuer
  • Sppls as Modifiers of the P53 Pathway and Methods of Use
    Publication number: 20070286852
    Abstract: Human SPPL genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of SPPL are provided.
    Type: Application
    Filed: June 18, 2004
    Publication date: December 13, 2007
    Applicant: Exelixis, Inc.
    Inventors: Marcia Belvin, Helen Francis-Lang, Lori Friedman, Gregory Plowman, Monique Nicoll, Timothy Heuer
  • Man2as as Modifiers of the Igfr Pathway and Methods of Use
    Publication number: 20070264268
    Abstract: Human MIGFR genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of MIGFR are provided.
    Type: Application
    Filed: January 27, 2005
    Publication date: November 15, 2007
    Applicant: EXELIXIS, INC.
    Inventors: Lori Friedman, Helen Francis-Lang, Annette Parks, Kenneth Shaw, HaiGuang Zhang, Timothy Heuer
  • HPRP4s Modifiers of the p53 Pathway and Methods of Use
    Publication number: 20070160539
    Abstract: Human hPRP4 genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of hPRP4 are provided.
    Type: Application
    Filed: January 26, 2007
    Publication date: July 12, 2007
    Applicant: EXELIXIS, INC.
    Inventors: Lori Friedman, Gregory Plowman, Tak Hung, Helen Francis-Lang, Danxi Li, Roel Funke, Michael Costa
  • Lces as modifiers of the p53 pathway and methods of use
    Publication number: 20070134732
    Abstract: Human LCE genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of LCE are provided.
    Type: Application
    Filed: June 3, 2002
    Publication date: June 14, 2007
    Inventors: Marcia Belvin, Helen Francis-Lang, Danxi Li, Roel Funke
  • Prkcs as modifiers of the beta catenin pathway and methods of use
    Publication number: 20070128606
    Abstract: Human PRKC genes are identified as modulators of the beta catenin pathway, and thus are therapeutic targets for disorders associated with defective beta catenin function. Methods for identifying modulators of beta catenin, comprising screening for agents that modulate the activity of PRKC are provided.
    Type: Application
    Filed: August 13, 2004
    Publication date: June 7, 2007
    Applicant: EXELIXIS INC
    Inventors: Helen Francis-Lang, Christopher Winter, Richard Benn Ventura, Joanne Adamkewicz, Timothy Heuer
  • Ttbks as modifiers of the beta catenin pathway and methods of use
    Publication number: 20070128666
    Abstract: Human TBK genes are identified as modulators of the beta catenin pathway, and thus are therapeutic targets for disorders associated with defective beta catenin function. Methods for identifying modulators of beta catenin, comprising screening for agents that modulate the activity of TTBK are provided.
    Type: Application
    Filed: November 23, 2004
    Publication date: June 7, 2007
    Inventors: Helen Francis-Lang, Christopher Winter, Richard Ventura, HaiGuang Zhang, Timothy Heuer
  • Tkts as mondifiers of the beta-catenin pathway and methods of use
    Publication number: 20070020628
    Abstract: Human TKT genes are identified as modulators of the beta-catenin pathway, and thus are therapeutic targets for disorders associated with defective beta-catenin function. Methods for identifying modulators of beta-catenin, comprising screening for agents that modulate the activity of TKT are provided.
    Type: Application
    Filed: January 28, 2004
    Publication date: January 25, 2007
    Inventors: Helen Francis-Lang, Christopher Winter, Richard Ventura, Kim Lickteig
  • Ups as modifiers of the beta catenin pathway and methods of use
    Publication number: 20060246459
    Abstract: Human UP genes are identified as modulators of the beta catenin pathway, and thus are therapeutic targets for disorders associated with defective beta catenin function. Methods for identifying modulators of beta catenin, comprising screening for agents that modulate the activity of UP are provided.
    Type: Application
    Filed: August 12, 2004
    Publication date: November 2, 2006
    Inventors: Helen Francis-Lang, Christopher Winter, Richard Ventura, Kim Lickteig, Timothy Heuer
  • Facls as modifiers of the rb pathway and methods of use
    Publication number: 20060240433
    Abstract: Human FACL genes are identified as modulators of the RB pathway, and thus are therapeutic targets for disorders associated with defective RB function. Methods for identifying modulators of RB, comprising screening for agents that modulate the activity of FACL are provided.
    Type: Application
    Filed: January 28, 2004
    Publication date: October 26, 2006
    Inventors: Helen Francis-Lang, Kyle Edgar, Kim Lickteig
  • LIMKs as modifiers of p53 pathway and methods of use
    Publication number: 20060160764
    Abstract: Human LIMK genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of LIMK are provided.
    Type: Application
    Filed: March 17, 2006
    Publication date: July 20, 2006
    Applicant: Exelixis, Inc.
    Inventors: Lori Friedman, Gregory Plowman, Marcia Belvin, Helen Francis-Lang, Danxi Li, Roel Funke