Abstract: The present invention is directed to compounds of formula IIa These compounds are considered useful for the treatment of diseases associated with leucine-rich repeat kinase 2 (LRRK2) such as Parkinson's disease. Furthermore, the invention relates to pharmaceutical compositions comprising said compounds.

Abstract: Idling a hydraulic machine includes electronically controlled high and low-pressure valves, a control system arranged to control opening and closing of said valves, a first idle safety valve arrangement arranged between the first working chamber and a fluid sink with a pressure equal to or lower than the high pressure, operating the hydraulic machine in an empty cylinder idle mode, wherein the high and low-pressure valves are concurrently closed for at least a whole cycle of the varying volume, and releasing hydraulic fluid to the fluid sink only when fluid pressure in the working chamber increases above a set threshold and the empty cylinder mode is enabled, enabling the first idle safety valve arrangement when the hydraulic machine operates in the empty cylinder idle mode, and disabling when not.

Abstract: A hearing device cerumen filter device is disclosed comprising: a body having a first end and a second end, the body comprising an inner surface defining a cavity, and an outer surface having an outer cross-sectional diameter, where the outer surface comprises a first support member positioned at a first distance from the first end, where the first support member has a first cross-sectional diameter, and the outer surface comprising a second support member positioned at a second distance from the first end, where the second support member has a second cross-sectional diameter; a filter structure positioned within the cavity of the body; and a collar positioned at the second end of the body, the collar having a collar cross-sectional diameter.

Abstract: Detergent compositions including polypeptide variants and methods of cleaning and/or treatment of surfaces using such compositions, and fabric treatment compositions including polypeptide variants. The compositions may include surfactants: anionic, nonionic and/or cationic.

Abstract: The present disclosure relates to a wirelessly rechargeable hearing device having inductive charging circuitry comprising a receiver coil, which has a plurality of receiver coil windings surrounding a winding-free area. The hearing device further comprises a magnetic component configured to magnetically engage with another magnetic component comprised outside the hearing device and the magnetic component is further arranged within a volume that extends perpendicularly from the winding-free area. Further, the disclosure relates to a charger for the wirelessly rechargeable hearing device, where the charger comprises a magnetic component arranged within a volume that extends perpendicularly from a winding-free area defined by transmitter coil windings. Lastly, a system comprising the wirelessly rechargeable hearing device and the charger is disclosed.

Abstract: The present invention relates to a gelling composition to produce a plant-based food product. The composition comprises a mixture of plant-based protein, salts of alginate and a calcium source. In addition, the invention also relates to the plant-based food product containing the composition and the process of producing the same.

Abstract: An in-the-ear (ITE) part includes: a connector for coupling with a BTE part; a hollow earmould comprising a front end, a rear end, and a hollow cavity, wherein the front end of the earmould is configured to face a tympanic membrane of the user, the front end comprising a front opening, the front opening comprising a front filter, the rear end comprising a rear opening; a receiver in the hollow cavity; a sound passage extending between the front opening and the rear end; an active vent, wherein when the active vent is in an open state, the active vent provides a fluid connection through the sound passage, and wherein when the active vent is in a closed state, the active vent hinders the fluid connection through the sound passage; and a rear filter at the rear opening, or in the hollow cavity between the rear opening and the active vent.

Abstract: A method of configuring a custom insert of a charger, wherein the custom insert is for aligning a first charging element of a hearing device and a transmitter charging element of a charger, includes: obtaining a digital three-dimensional hearing device model comprising a representation of the first charging element; obtaining a digital three-dimensional charger model comprising a representation of the transmitter charging element; obtaining a digital three-dimensional insert model; obtaining a digital cavity representing a cavity in the custom insert; and creating a custom digital three-dimensional insert model based on the digital cavity and the digital three-dimensional insert model, such that the representation of the first charging element in the digital three-dimensional hearing device model and the representation of the transmitter charging element in the three-dimensional charger model, are aligned.

Abstract: A method of configuring a custom insert of a charger, wherein the custom insert is for aligning a first charging element of a hearing device and a transmitter charging element of a charger, includes: obtaining a digital three-dimensional hearing device model comprising a representation of the first charging element; obtaining a digital three-dimensional charger model comprising a representation of the transmitter charging element; obtaining a digital three-dimensional insert model; obtaining a digital cavity representing a cavity in the custom insert; and creating a custom digital three-dimensional insert model based on the digital cavity and the digital three-dimensional insert model, such that the representation of the first charging element in the digital three-dimensional hearing device model and the representation of the transmitter charging element in the three-dimensional charger model, are aligned.

Abstract: Provided is a hearing device comprising an earmould. The earmould comprises a front end, a rear end opposite the front end, and a middle part arranged in-between the front and a rear end. The front end comprises a front opening, and the rear end comprises a rear opening. The earmould is configured for the front end to be positioned facing a tympanic membrane of the user during use. The hearing device further comprises a receiver housing arranged at least partly within the earmould, and a supporting structure configured to hold the receiver housing in place within the earmould. At least part of the supporting structure comprises a material that is softer than the material used to make the middle part of the earmould.

Abstract: A hearing device includes: an earmould having a front end comprising a front opening, a rear end, and a middle part, the front end of the earmould configured to face a tympanic membrane, the front opening being in fluid communication with an outside of an ear canal; a receiver housing at least partly in the earmould, the receiver housing accommodating a receiver; a sound passage extending at least between the front opening and the rear end; an active vent between an end of the receiver housing and the front opening of the earmould, wherein when the active vent is in an open state, the active vent allows sound transmission through the sound passage, and wherein when the active vent is in a closed state, the active vent hinders the sound transmission; and a supporting structure configured to maintain the receiver housing in place with respect to the earmould.

Abstract: A method of manufacturing a charger insert part of a hearing instrument charger device comprising a charger casing having a receiving portion, and a first charger element, includes: obtaining a first virtual model of the rechargeable hearing instrument shaped or to be shaped to at least partly conform to a shape of a portion of an ear canal of a user, wherein the first virtual model comprises an allocated position for a second charger element; obtaining a second virtual model of the charger insert part for manufacturing the charger insert part, such that when the charger insert part is placed in the receiving portion, the first charger element will be in a relation with the second charger element; and shaping, by a manufacturing process, the charger insert part based on the second virtual model, the second virtual model being based on the first virtual model.

Abstract: A hearing instrument charger device for charging an individually shaped hearing instrument, includes: a charger casing; a charger power supply within the charger casing; a first charger coil connected to the charger power supply; charger electronics for controlling charging of the hearing instrument; and a holder configured for receiving the hearing instrument, the holder located within the charger casing; wherein the holder for the hearing instrument has a shape that is specific for the individually shaped hearing instrument, such that when the individually shaped hearing instrument is received in the holder, a second charger coil of the individually shaped hearing instrument is in an operative position for receiving charging power from the first charger coil of the hearing instrument charger device.

Abstract: The disclosure relates to a hearing aid for placement in an ear canal, the hearing aid having a proximal end and a distal end, the proximal end is inserted into the ear canal to face the tympanic membrane, the distal end is opposite. The hearing aid comprises a shell customized for the ear canal. The shell comprises an inner space configured for at least partly receiving a rechargeable battery, a charging arrangement, at least one microphone arrangement, and an integrated circuit. The hearing aid comprises a faceplate comprising an upper face and a lower face, the upper face being exposed at the distal end when the shell is placed in the user's ear canal. The faceplate is configured for closing the inner space, wherein the IC is arranged between the faceplate and the proximal end.

Abstract: A hearing aid for placement in an ear canal of a user, includes: a shell; a faceplate comprising an upper face, and a lower face, and a circumference, the upper face being exposed when the shell is placed in an ear of the user; a coil arranged at the faceplate; and a button arrangement comprising a plunger configured to control an integrated circuit arranged below the coil, the coil comprising one or more windings, the one or more windings being circumferential of an inner cavity of the coil with respect to a center or longitudinal axis of the coil, the button arrangement being configured such that the plunger in at least one position extends through the inner cavity of the coil for engaging the integrated circuit.

Abstract: The present invention is directed to a composition of colloidal microcrystalline cellulose, particularly for developing (uplifting) premium texture in various types of fermented or acidified milk products, preferably, yoghurt types, produced by using a colloidal microcrystalline cellulose and at least one other hydrocolloid, products made therewith and process for production of these products. The present invention is mainly directed to fermented or acidified milk products as yogurt type and ambient stable yogurt.

Abstract: A hearing instrument charger device for charging an individually shaped hearing instrument, includes: a charger casing; a charger power supply within the charger casing; a first charger coil connected to the charger power supply; charger electronics for controlling charging of the hearing instrument; and a holder configured for receiving the hearing instrument, the holder located within the charger casing; wherein the holder for the hearing instrument has a shape that is specific for the individually shaped hearing instrument, such that when the individually shaped hearing instrument is received in the holder, a second charger coil of the individually shaped hearing instrument is in an operative position for receiving charging power from the first charger coil of the hearing instrument charger device.

Abstract: A button structure for a hearing device, includes: a first microphone, the first microphone being configured to receive sound via a first microphone input; an elastic member comprising a first part and a second part, the first part comprising a user interface surface, the second part comprising a first opening, the first opening being aligned with the first microphone input; a switch component, wherein the user interface surface is configured to be operated by a user to activate the switch component; and an outer shielding comprising a shield opening and a second opening, wherein at least a portion of the first part of the elastic member extends through the shield opening, wherein the second opening of the outer shield is aligned with the first opening of the second part of the elastic member, and wherein the outer shielding is in contact with the elastic member to create a seal.

Abstract: The present disclosure relates to a wirelessly rechargeable in-ear hearing device, a charger for a wirelessly rechargeable in-ear hearing device, and a system comprising a wirelessly rechargeable in-ear hearing device and a charger for the wirelessly rechargeable in-ear hearing device.

Abstract: The invention relates to a hearing device. The hearing device comprises an outer shell, the outer shell defining an outer compartment. The hearing device further comprises a receiver, and a rechargeable battery electrically connected to the receiver. Finally, the hearing device comprises a sealed inner compartment arranged in the outer compartment, wherein the receiver and the rechargeable battery are both arranged in the sealed inner compartment.