Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: Disclosed are novel compounds of Formula I that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: This disclosure details a base station and client devices using dynamic spectrum access for communication within a frequency spectrum by selecting channels dynamically for efficient communication. This includes identifying active uplink and downlink channels from an available list and allocating them to multiple client devices based on their locations, with some devices sharing common active channels. A downlink channel is designated as a beaconing channel, used for beaconing with embedded information, including the coordinates of a region among a plurality of regions, available channels for the region, and a buffer slot in the channels, during a beaconing period occurring outside regular transmission times. Acknowledgments with medium access control (MAC) commands for an identified subset of client devices sharing an active channel are grouped and transmitted, with each message in the plurality of messages on the uplink channels followed by a downlink acknowledgment.

Abstract: The disclosure described herein configures a base station and client devices for communication using dynamic spectrum access within a frequency spectrum that includes selecting, from a list of available channels, a set of channels as active channels. The active channels include uplink channels and downlink channels. An uplink channel and a downlink channel are assigned to a plurality of client devices based on locations the client devices, wherein at least some client devices have active channels in common. Acknowledgements from the subset of client devices having the common active channel are grouped, the acknowledgements containing medium access control (MAC) commands specific to the subset of client devices, where each message of a plurality of messages on the uplink channels is followed by a downlink acknowledgement.

Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: The disclosure described herein configures a multi-narrowband transceiver for communication within the television white space (TVWS) frequency spectrum using a log periodic filter, wherein the log periodic filter comprises a plurality of filter elements each having a filter frequency increasing periodically in a same frequency increasing factor (K). Each filter of the plurality of filter elements is configured to filter out second harmonics in a defined frequency range. The disclosure determines a TVWS channel for the communication and switches to a filter element of the plurality of filter elements corresponding to the determined TVWS channel. Data is transmitted and/or received over the TVWS channel using the filter element, thereby allowing narrowband communication over the TVWS channel.

Abstract: Disclosed are novel compounds of Formula I that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: Disclosed are novel compounds of Formula I that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: The disclosure described herein configures a base station and client devices for communication using dynamic spectrum access within a frequency spectrum that includes selecting, from a list of available channels, a set of channels as active channels. The active channels include uplink channels and downlink channels. An uplink channel and a downlink channel are assigned to a plurality of client devices based on locations the client devices, wherein at least some client devices have active channels in common. Acknowledgements from the subset of client devices having the common active channel are grouped, the acknowledgements containing medium access control (MAC) commands specific to the subset of client devices, where each message of a plurality of messages on the uplink channels is followed by a downlink acknowledgement.

Abstract: The disclosure described herein configures a multi-narrowband transceiver for communication within the television white space (TVWS) frequency spectrum using a log periodic filter, wherein the log periodic filter comprises a plurality of filter elements each having a filter frequency increasing periodically in a same frequency increasing factor (K). Each filter of the plurality of filter elements is configured to filter out second harmonics in a defined frequency range. The disclosure determines a TVWS channel for the communication and switches to a filter element of the plurality of filter elements corresponding to the determined TVWS channel. Data is transmitted and/or received over the TVWS channel using the filter element, thereby allowing narrowband communication over the TVWS channel.

Abstract: The present disclosure provides compounds that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Abstract: The disclosure described herein configures a base station and client devices for communication using dynamic spectrum access within a frequency spectrum that includes selecting, from a list of available channels, a set of channels as active channels. The active channels include uplink channels and downlink channels, and the active channels are distributed among a plurality of base station radios of a base station. A different channel is assigned to different base station radios. At least one uplink channel and at least one downlink channel are assigned to a plurality of client devices based on locations the client devices, wherein at least some client devices have active channels in common. The client devices having the active channels in common are also grouped on shared channels and time slots assigned to the client devices in the group, thereby allowing narrowband communication over the channels by the client devices.

Abstract: The disclosure described herein configures a multi-narrowband transceiver for communication within the television white space (TVWS) frequency spectrum using a log periodic filter, wherein the log periodic filter comprises a plurality of filter elements each having a filter frequency increasing periodically in a same frequency increasing factor (K). Each filter of the plurality of filter elements is configured to filter out second harmonics in a defined frequency range. The disclosure determines a TVWS channel for the communication and switches to a filter element of the plurality of filter elements corresponding to the determined TVWS channel. Data is transmitted and/or received over the TVWS channel using the filter element, thereby allowing narrowband communication over the TVWS channel.

Abstract: The disclosure described herein configures a client device for communication using dynamic spectrum access within a frequency spectrum, such as television white space (TVWS), using a determined location of the client device based on location information, such as from a global positioning system. A dynamic spectrum access database of channels is accessed based on the location information. Available channels are determined for the client device from the channels based on the location information. A list of the available channels for use by the client device are transmitted to the client device, thereby allowing narrowband communication over the channels.

Abstract: The disclosure described herein configures a client device for communication using dynamic spectrum access within a frequency spectrum, such as television white space (TVWS), using a determined location of the client device based on location information, such as from a global positioning system. A dynamic spectrum access database of channels is accessed based on the location information. Available channels are determined for the client device from the channels based on the location information. A list of the available channels for use by the client device are transmitted to the client device, thereby allowing narrowband communication over the channels.